nitrofen has been researched along with Disease Models, Animal in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (11.11) | 18.2507 |
| 2000's | 55 (32.16) | 29.6817 |
| 2010's | 82 (47.95) | 24.3611 |
| 2020's | 15 (8.77) | 2.80 |
| Authors | Studies |
|---|---|
| Hirako-Takamura, S; Iitani, Y; Imai, K; Ito, Y; Kajiyama, H; Kotani, T; Miki, R; Miura, M; Moriyama, Y; Nakano-Kobayashi, T; Tano, S; Toyokuni, S; Tsuda, H; Ushida, T | 1 |
| Kahnamoui, S; Keijzer, R; Khoshgoo, N; Patel, D; Wagner, R | 1 |
| Deprest, J; Derraugh, G; Gosemann, JH; Keijzer, R; Lacher, M; Lieckfeldt, P; Markel, M; Min, SAL; Mookherjee, N; Pascoe, CD; Patel, D; Peukert, N; Piyadasa, H; Riedel, J; Stefanovici, C; Tse, WH; Wagner, R | 1 |
| Antounians, L; Biouss, G; Figueira, RL; Gandhi, S; Khalaj, K; Montalva, L; Wales, M; Zani, A | 1 |
| Fauza, DO; Kycia, I; Labuz, DF; Whitlock, AE; Zurakowski, D | 1 |
| Takayasu, H | 1 |
| Aptekmann, AO; Keijzer, R; Leon, N; Miyake, Y; Mourin, M; Patel, D; Tse, WH; Wang, JQ; Yamataka, A | 1 |
| Ai, X; Amonkar, GM; Bankoti, K; Buchmiller, TL; Donahoe, PK; High, FA; Keijzer, R; Lerou, PH; Shui, JE; Tse, WH; Wagner, R; Wang, W; Zalieckas, JM; Zani, A | 1 |
| Ferrer-Marquez, F; Lampe, K; Martinez, L; Oria, M; Peiro, JL; Romero-Lopez, M; Varela, MF; Watanabe-Chailland, M | 1 |
| Asosingh, K; Bazeley, P; Erzurum, SC; Robertson, JO | 1 |
| Ai, X; Amonkar, GM; Bode, LM; Dylong, F; Gosemann, JH; Höxter, B; Keijzer, R; Lacher, M; Lieckfeldt, P; Mayer, S; Miyake, Y; Moormann, M; Peukert, N; Riedel, J; Sturm, K; Tse, WH; Wagner, R | 1 |
| Day, C; Eastwood, P; Iwasiow, B; Keijzer, R; Khoshgoo, N; Mulhall, D; Visser, R; Zhu, F | 1 |
| Hirako-Takamura, S; Imai, K; Ito, Y; Kajiyama, H; Kikkawa, F; Kobayashi, T; Kotani, T; Miki, R; Miura, M; Moriyama, Y; Sumigama, S; Tachi, A; Tano, S; Tsuda, H; Ushida, T | 1 |
| Chalphin, AV; Fauza, DO; Kycia, I; Labuz, DF; Lazow, SP; Tracy, SA; Zurakowski, D | 1 |
| Agopsowicz, K; Garcia, E; Hitt, MM; Jay, DA; Luna, I; Persad, KL; Persad, S; West, FG | 1 |
| Lim, T; Nakamura, H; Puri, P; Zimmer, J | 1 |
| Bair, H; Harting, MT; Jin, D; Lu, J; Olson, SD; Zhaorigetu, S | 1 |
| Friedmacher, F; Puri, P; Takahashi, T; Zimmer, J | 7 |
| Antounians, L; Belfiore, A; Ma, Q; Pellerito, O; Stasiewicz, M; Tzanetakis, A; Zani, A | 1 |
| Montalva, L; Zani, A | 1 |
| Alvarez, L; Corcionivoschi, N; Friedmacher, F; Gosemann, JH; Hofmann, A; Kuebler, JF; Lacher, M; Puri, P; Rittinghausen, S; Suttkus, A; Zimmer, J | 1 |
| Ahmed, M; Alabed, Y; Ayasolla, K; Benveniste, H; Miller, EJ; Nasim, M; Ochani, K; Orner, D; Patel, H; Perveen, S; Salerno, M; Vaska, P; Zagloul, N; Zuo, Z | 1 |
| Antounians, L; Montalva, L; Zani, A | 1 |
| Deprest, J; Jimenez, J; Müller, C; Nguyen, TM; Rendin, LE; Toelen, J; Westergren-Thorsson, G | 1 |
| Dingemann, J; Doi, T; Gosemann, JH; Nakazawa, N; Puri, P; Ruttenstock, EM | 1 |
| Friedmacher, F; Fujiwara, N; Gosemann, JH; Hofmann, A; Kutasy, B; Puri, P; Takahashi, H | 1 |
| Friedmacher, F; Fujiwara, N; Gosemann, JH; Hofmann, A; Puri, P; Takahashi, H | 1 |
| Alvarez, LA; Corcionivoschi, N; Friedmacher, F; Fujiwara, N; Gosemann, JH; Puri, P | 1 |
| Duess, JW; Friedmacher, F; Kutasy, B; Puri, P | 1 |
| Friedmacher, F; Gosemann, JH; Hofmann, AD; Hunziker, M; Puri, P; Takahashi, H | 1 |
| Gallindo, RM; Garcia, PV; Gonçalves, FL; Nassr, AC; Pereira, LA; Sbragia, L; Schmidt, AF; Zuliani, CC | 1 |
| Di Bernardo, J; Hershenson, MB; Kunisaki, SM; Maiden, MM | 1 |
| Friedmacher, F; Kutasy, B; Paradisi, F; Pes, L; Puri, P | 2 |
| Duess, JW; Friedmacher, F; Gosemann, JH; Hofmann, AD; Hunziker, M; Puri, P; Takahashi, H | 1 |
| Friedmacher, F; Hofmann, AD; Puri, P; Takahashi, H; Takahashi, T | 2 |
| Alatas, FS; Esumi, G; Kinoshita, Y; Kuda, M; Nagata, K; Taguchi, T; Yamaza, T; Yanagi, Y; Yuniartha, R | 1 |
| Kutasy, B; Paradisi, F; Pes, L; Puri, P; Takahashi, H | 1 |
| Aoi, S; Fumino, S; Furukawa, T; Higuchi, K; Kimura, K; Kimura, O; Masumoto, K; Sakai, K; Tajiri, T; Wakao, J | 1 |
| Gómez-Meda, BC; Lemus-Varela, Mde L; Melnikov, V; Ornelas-Aguirre, JM; Soliz, A; Torres-Mendoza, BM; Zamora-Perez, AL; Zúñiga-González, GM | 1 |
| Gotoh, C; Hagiwara, K; Jimbo, T; Masumoto, K; Ono, K; Sasaki, T; Shinkai, T; Takayasu, H; Tanaka, H; Uesugi, T; Urita, Y | 1 |
| Gittes, GK; Potoka, DA; Rhodes, J; Saxena, D; Zhang, G | 1 |
| Aras-López, R; Martínez, L; Tovar, JA | 1 |
| Duess, JW; Hofmann, AD; Puri, P; Takahashi, T; Zimmer, J | 1 |
| Friedmacher, F; Kutasy, B; Puri, P; Takahashi, H; Takahashi, T | 1 |
| Coyle, D; Doi, T; Friedmacher, F; Kutasy, B; Paradisi, F; Pes, L; Puri, P | 1 |
| Hirako, S; Imai, K; Kikkawa, F; Kotani, T; Li, H; Mano, Y; Nakano, T; Sumigama, S; Toyokuni, S; Tsuda, H | 1 |
| He, TZ; Ji, Y; Jiang, J; Li, TM; Liu, M; Xiao, B; Xu, C | 1 |
| Hofmann, AD; Puri, P; Takahashi, T; Zimmer, J | 2 |
| Hagiwara, K; Masumoto, K; Takayasu, H | 1 |
| Deprest, JA; Klaritsch, P; Mayer, S; Sbragia, L; Till, H; Toelen, J | 1 |
| Clugston, RD; Greer, JJ; Zhang, W | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, E | 8 |
| Doi, T; Puri, P; Sugimoto, K | 1 |
| Aras, R; Bret, M; Cuesta, E; Luis, AL; Martinez, L; Pederiva, F; Tovar, JA | 1 |
| Dingemann, J; Doi, T; Lukosiūte, A; Puri, P; Ruttenstock, E | 1 |
| Doi, T; Puri, P | 1 |
| Celik, Y; Cigdem, MK; Kizil, G; Kizil, M; Nergiz, Y; Onen, A | 1 |
| Lopez, RA; Martinez, L; Pederiva, F; Rodriguez, JI; Tovar, JA | 1 |
| Eaton, F; Morgan, B; Reiss, I; Thébaud, B; Tibboel, D; van der Horst, IW | 1 |
| Farmer, D; Gonçalves, FL; Nassr, AC; Pereira, LA; Sbragia, L; Schmidt, AF | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, E; Sugimoto, K | 2 |
| Burgos, CM; Eklöf, AC; Fagerström-Billai, F; Frenckner, B; Nord, M; Uggla, AR | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, EM | 3 |
| Burgos, CM; Didon, L; Eklöf, AC; Frenckner, B; Nord, M; Roos, A | 1 |
| Doi, T; Murphy, P; Puri, P; Sato, H; Takayasu, H | 1 |
| Esumi, G; Kinoshita, Y; Masumoto, K; Nagata, K; Nonaka, K; Taguchi, T; Teshiba, R; Yamaza, H | 1 |
| Dingemann, J; Doi, T; Lukošiūtė, A; Puri, P; Ruttenstock, EM | 1 |
| Chen, G; Chen, L; Qiao, YL; Xiao, XM; Zheng, S | 1 |
| Archer, SL; Dyck, JR; Eaton, F; Gilmour, G; Gressens, P; Kassiri, Z; Koonen, D; Luong, C; Morgan, B; Nadeem, K; Rey-Perra, J; Sauve, Y; Thébaud, B; Todd, KG; Vadivel, A; Walker, D | 1 |
| Connell, MG; Fernig, DG; Jesudason, EC; Losty, PD; Thompson, SM; Turnbull, JE; van Kuppevelt, TH; Xu, R | 1 |
| Kluth, D; Mayer, S; Metzger, R | 1 |
| Doi, T; Friedmacher, F; Fujiwara, N; Gosemann, JH; Kutasy, B; Puri, P | 2 |
| Beck, V; Davey, MG; Deckx, S; Deprest, JA; Froyen, G; Klaritsch, P; Mayer, S; Petersen, SG; Roubliova, XI | 1 |
| Chang, YT; Eklöf, AC; Frenckner, B; Hedin, U; Lengquist, M; Osterholm, C; Ringman Uggla, A; Tran, PK; Tran-Lundmark, K | 1 |
| Connell, MG; Corbett, HJ; Fernig, DG; Jesudason, EC; Losty, PD | 1 |
| Dingemann, J; Doi, T; Friedmacher, F; Gosemann, JH; Kutasy, B; Puri, P | 1 |
| Gallindo, RM; Gonçalves, FL; Regis, AC; Sbragia, L; Schmidt, AF | 1 |
| Duess, JW; Gosemann, JH; Kutasy, B; Puri, P | 1 |
| Corcionivoschi, N; Friedmacher, F; Gosemann, JH; Puri, P; Takahashi, H | 1 |
| Figueira, RL; Gallindo, RM; Gonçalves, FL; Oliveira, FS; Pereira, LA; Sbragia, L; Schmidt, AF | 1 |
| Anderson, KD; Coleman, C; Leinwand, MJ; Tefft, JD; Warburton, D; Zhao, J | 1 |
| Allan, DW; Babiuk, RP; Clugston, R; Greer, JJ; Zhang, W | 1 |
| Belik, J; Davidge, ST; Greer, JJ; Pan, J; Zhang, W | 1 |
| Bavik, C; Chen, MH; Greer, JJ; MacGowan, A; Ward, S | 1 |
| Diez-Pardo, JA; Gonzalez-Reyes, S; Martínez, I; Martínez, L; Rodriguez, JI; Rodriguez-Matas, MJ; Tovar, JA | 1 |
| Balcerazak, D; Baracos, VE; Cheung, PY; Dixon, WT; Greer, JJ; Kobayashi, K; Lemke, RP; Schwingshackl, A; Zhang, W | 1 |
| Blommaart, Pj; Keijzer, R; Lamers, WH; Ruijter, J; Tibboel, D; Van Tuyl, M; Wert, SE | 1 |
| Baglaj, SM; Czernik, J | 1 |
| Hu, T; Jiang, X; Li, J; Liu, W; Xiang, B | 1 |
| Babiuk, RP; Greer, JJ; Thébaud, B | 1 |
| Heintz, CK; Mychaliska, GB; Officer, SM; Pierce, RA; Starcher, BC | 1 |
| Andreoli, S; Chang, R; D'Amore, PA; Ng, YS; Smith, SR; Truong, T; Wilson, J | 1 |
| Alaamian, M; Beshir, I; Fiegel, HC; Izbicki, JR; Kluth, D; Langwieler, T; Mann, O | 1 |
| Puri, P; Shinkai, M; Teramoto, H | 1 |
| Fernandez-Dumont, V; Gonzalez-Reyes, S; Hernandez, F; Martinez, L; Martinez-Calonge, W; Tovar, J | 1 |
| Puri, P; Shima, H; Shinkai, T; Solari, V | 1 |
| Eklöf, AC; Eriksson, H; Frenckner, B; Masironi, B; Sahlin, L | 1 |
| Areias, JC; Baptista, MJ; Correia-Pinto, J; Estevão-Costa, J; Flake, AW; Gonzaga, S; Leite-Moreira, AF; Melo-Rocha, G; Pedrosa, C; Teles, A | 1 |
| Montedonico, S; Pirker, ME; Puri, P; Shinkai, M; Shinkai, T | 1 |
| González-Reyes, S; Martínez, L; Tovar, JA | 1 |
| Coppola, CP; Gosche, JR; Hults, C; Vukcevic, Z | 1 |
| Calonge, WM; Fernandez-Dumont, V; Gonzalez-Reyes, S; Martinez, L; Tovar, JA | 1 |
| Connell, MG; Corbett, HJ; Jesudason, EC; Losty, PD; Purvis, A | 1 |
| Cohen, JC; Larson, JE | 1 |
| Chinoy, MR; Cilley, RE; Donahue, H; Le, M; Li, Z | 1 |
| Areias, JC; Baptista, MJ; Correia-Pinto, J; Gonzaga, S; Leite-Moreira, A; Melo-Rocha, G; Nogueira-Silva, C; Recamán, M; Roriz, JM; Santos, M; Soares-Fernandes, J | 1 |
| Montedonico, S; Nakazawa, N; Puri, P; Takayasu, H | 3 |
| Montedonico, S; Nakazawa, N; Paradisi, F; Puri, P; Takayasu, H | 1 |
| Kling, DE; Schnitzer, JJ | 1 |
| Chen, ZX; Liu, WY; Wang, YG; Xiong, ZX; Xu, C | 1 |
| Anselmo, M; Baird, R; Flageole, H; Khan, N; Laberge, JM; Puligandla, P | 1 |
| Cheng, ZX; Liu, WY; Wang, YX; Xiong, ZX; Xu, C | 1 |
| Puri, P; Sato, H; Sugimoto, K; Takayasu, H | 1 |
| Montedonico, S; Nakazawa, N; Puri, P; Sugimoto, K; Takayasu, H | 1 |
| Bannigan, J; Felle, P; Montedonico, S; Puri, P; Sugimoto, K | 1 |
| Correia-Pinto, J; Esteves, N; Gonzaga, S; Moura, RS; Nogueira-Silva, C | 1 |
| Glick, PL; Holm, BA; Karamanoukian, H; Wilcox, DT | 1 |
| Aldazabal, P; Alfonso, LF; Lopez de Torre, B; Tovar, JA; Vilanova, J | 1 |
| Glick, PL; Karamanoukian, HL; O'Toole, SJ | 1 |
| Abdel-Rahman, E; Azizkhan, RG; Dandonna, P; Glick, PL; Karamanoukian, HL; Love, JE; Peay, T | 1 |
| Hertl, M; Keijzer, R; Kluth, D; Tibboel, D | 1 |
| Chinoy, MR; Cilley, RE; Krummel, TM; Zgleszewski, SE | 1 |
| Alfonso, LF; Alvarez, FJ; Arnaiz, A; Diez-Pardo, JA; Morreale de Escobar, G; Qi, B; Tovar, JA; Valls-i-Soler, A | 1 |
| Miyazaki, E; Ohshiro, K; Puri, P; Taira, Y; Yamataka, T | 1 |
| Au-Fliegner, M; Coppola, CP; Gosche, JR | 1 |
| Au-Fliegner, M; Coppola, CP; Gosche, JR; Newell, MA | 1 |
| Au-Fliegner, M; Gosche, JR; Salami, S | 1 |
| Alfonso, LF; Alvarez, JI; Arnaiz, A; Diez-Pardo, JA; Migliazza, L; Tovar, JA; Xia, H | 1 |
| Miyazaki, E; Oue, T; Puri, P; Shima, H; Taira, Y | 2 |
| Adzick, NS; Davies, P; Flake, AW; Kitano, Y; von Allmen, D | 1 |
| Diez-Pardo, JA; Migliazza, L; Tovar, JA; Xia, H | 1 |
| Chi, JG; Kim, WG; Suh, JW | 1 |
| Allan, DW; Babiuk, RP; Greer, JJ; Lemke, RP | 1 |
| Battistini, B; Cloutier, R; Fournier, L; Jean, S; Jeng, AY; Kavanagh, M; Kluth, D; Major, D | 1 |
| Miyazaki, E; Ohshiro, K; Puri, P; Shima, H; Taira, Y | 1 |
| Gebb, SA; Guilbert, TW; Shannon, JM | 1 |
| Adzick, NS; Davies, P; Flake, AW; Kanai, M; Kitano, Y; Radu, A; von Allmen, D; Yang, EY | 1 |
| Hashizume, K; Iwamori, M; Utsuki, T | 1 |
| Coppola, CP; Gosche, JR | 1 |
| Guarino, N; Puri, P; Shima, H | 2 |
| Puri, P; Teramoto, H | 1 |
| Diez-Pardo, JA; Gonzalez, S; Rodriguez, JI; Tovar, JA; Yu, J | 1 |
| Barlier-Mur, AM; Bourbon, JR; Chailley-Heu, B; Dinh-Xuan, AT; Henrion-Caude, A; Thébaud, B; Tibboel, D | 1 |
| Feng, J; Hu, T; Hu, X; Jia, H; Jiang, X; Liu, W; Tang, Y | 1 |
| Aldazabal, P; Alfonso, LF; Lopez de Torre, B; Tovar, JA; Uriarte, S; Vilanova, J | 1 |
| Bos, AP; Koster, JF; Kraakslee, R; Molenaar, JC; Silveri, F; Sluiter, W; Tenbrinck, R; Tibboel, D | 1 |
| Kangah, R; Kluth, D; Lambrecht, W; Reich, P; Tenbrinck, R; Tibboel, D | 1 |
3 review(s) available for nitrofen and Disease Models, Animal
| Article | Year |
|---|---|
Pulmonary hypertension secondary to congenital diaphragmatic hernia: factors and pathways involved in pulmonary vascular remodeling.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Endothelial Cells; Female; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Myocytes, Smooth Muscle; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Risk Factors; Vascular Remodeling | 2019 |
The embryology of the diaphragm.
Topics: Animals; Diaphragm; Disease Models, Animal; Hernia; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Liver; Lung; Mesoderm; Microscopy, Electron, Scanning; Peritoneum; Pesticides; Phenyl Ethers; Pleural Cavity; Rats | 2011 |
Recent advances in understanding the pathogenesis of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Muscle, Skeletal; Phenyl Ethers; Rats | 2000 |
168 other study(ies) available for nitrofen and Disease Models, Animal
| Article | Year |
|---|---|
Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
Topics: Animals; Animals, Newborn; Antioxidants; Deuterium Oxide; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Hydrogen; Hypertension, Pulmonary; Lung; Male; Organogenesis; Phenyl Ethers; Pregnancy; Pulmonary Artery; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2021 |
Yes-associated protein is dysregulated during nitrofen-induced hypoplastic lung development due to congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Humans; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley; YAP-Signaling Proteins | 2022 |
Proteomic Profiling of Hypoplastic Lungs Suggests an Underlying Inflammatory Response in the Pathogenesis of Abnormal Lung Development in Congenital Diaphragmatic Hernia.
Topics: Animals; Disease Models, Animal; Epstein-Barr Virus Infections; Hernias, Diaphragmatic, Congenital; Herpesvirus 4, Human; Humans; Lung; Lung Diseases; Proteomics; Rats; Rats, Sprague-Dawley; Tenascin | 2023 |
Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia.
Topics: Amniotic Fluid; Animals; beta Catenin; Cell Differentiation; Disease Models, Animal; Ephrins; Extracellular Vesicles; Hernias, Diaphragmatic, Congenital; Lung; MicroRNAs; Neuropilin-1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stem Cells | 2022 |
Early functional analysis on the pulmonary hemodynamic effects of Transamniotic Stem Cell Therapy (TRASCET) in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Hemodynamics; Hernias, Diaphragmatic, Congenital; Lung; Mesenchymal Stem Cell Transplantation; Phenyl Ethers; Pregnancy; Rats | 2023 |
Upregulated TSP1 and CD47 expression in the lung in nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; CD47 Antigen; Disease Models, Animal; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Rats; Rats, Sprague-Dawley; Thrombospondin 1 | 2023 |
The effect of tracheal occlusion in congenital diaphragmatic hernia in the nitrofen rat lung explant model.
Topics: Airway Obstruction; Animals; Caspase 3; Disease Models, Animal; Hernias, Diaphragmatic, Congenital; Ki-67 Antigen; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2022 |
A Tracheal Aspirate-derived Airway Basal Cell Model Reveals a Proinflammatory Epithelial Defect in Congenital Diaphragmatic Hernia.
Topics: Animals; Disease Models, Animal; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; NF-kappa B; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2023 |
Fetal lung hypoxia and energetic cell failure in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Hernias, Diaphragmatic, Congenital; Humans; Hypoxia; Lung; Lung Diseases; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2023 |
Single-cell transcriptomic profiling of microvascular endothelial cell heterogeneity in congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Hernias, Diaphragmatic, Congenital; Humans; Lung; Rats; Rats, Sprague-Dawley; Transcriptome | 2023 |
Overactivated Epithelial NF-κB Disrupts Lung Development in Congenital Diaphragmatic Hernia.
Topics: Animals; Dexamethasone; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Humans; Lung; Lung Diseases; NF-kappa B; Pregnancy; Rats; Rats, Sprague-Dawley | 2023 |
miR-200 family expression during normal and abnormal lung development due to congenital diaphragmatic hernia at the later embryonic stage in the nitrofen rat model.
Topics: Animals; Disease Models, Animal; Female; Gene Expression; Hernias, Diaphragmatic, Congenital; In Situ Hybridization, Fluorescence; Lung; MicroRNAs; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2020 |
Vitamin D improves pulmonary function in a rat model for congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Hernias, Diaphragmatic, Congenital; Humans; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Vitamin D | 2021 |
Transamniotic Stem Cell Therapy for Experimental Congenital Diaphragmatic Hernia: Structural, Transcriptional, and Cell Kinetics Analyses in the Nitrofen Model.
Topics: Animals; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Kinetics; Lung; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Phenyl Ethers; Pregnancy | 2021 |
Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Discovery; Epithelial-Mesenchymal Transition; Female; Humans; Mice; Molecular Structure; Neoplasm Invasiveness; Phenyl Ethers; Rats; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2021 |
Increased CaSR and TRPC6 pulmonary vascular expression in the nitrofen-induced model of congenital diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Calcium-Sensing; RNA; TRPC Cation Channels | 2018 |
Perturbations in Endothelial Dysfunction-Associated Pathways in the Nitrofen-Induced Congenital Diaphragmatic Hernia Model.
Topics: Animals; Animals, Newborn; Carrier Proteins; Caveolin 1; Disease Models, Animal; Endothelium, Vascular; Female; Gestational Age; Hernias, Diaphragmatic, Congenital; Maternal Exposure; Myosin Light Chains; Nitric Oxide Synthase Type III; Phenyl Ethers; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Artery; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Remodeling | 2018 |
Expression of dispatched RND transporter family member 1 is decreased in the diaphragmatic and pulmonary mesenchyme of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Biomarkers; Disease Models, Animal; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Membrane Proteins; Mesoderm; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA | 2019 |
Endoplasmic reticulum stress response is activated in pulmonary hypoplasia secondary to congenital diaphragmatic hernia, but is decreased by administration of amniotic fluid stem cells.
Topics: Abnormalities, Multiple; Amniotic Fluid; Animals; Apoptosis; Cell- and Tissue-Based Therapy; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Stem Cells | 2019 |
Assessment of the nitrofen model of congenital diaphragmatic hernia and of the dysregulated factors involved in pulmonary hypoplasia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Down-Regulation; Female; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Mesoderm; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2019 |
Prenatal treatment with rosiglitazone attenuates vascular remodeling and pulmonary monocyte influx in experimental congenital diaphragmatic hernia.
Topics: Animals; Chemokine CCL2; Disease Models, Animal; Female; Gene Expression; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Macrophages; Monocytes; Phenyl Ethers; Pregnancy; Prenatal Care; Rats; RNA, Messenger; Rosiglitazone; Vascular Remodeling | 2018 |
MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Female; Hemodynamics; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Immunity, Innate; Inflammation; Intramolecular Oxidoreductases; Lung; Macrophage Migration-Inhibitory Factors; Maternal Exposure; Neovascularization, Physiologic; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Systole; Tomography, X-Ray Computed; Vascular Remodeling; Ventricular Function, Right | 2019 |
The proportion of alveolar type 1 cells decreases in murine hypoplastic congenital diaphragmatic hernia lungs.
Topics: Alveolar Epithelial Cells; Animals; Cell Count; Cell Differentiation; Diamines; Disease Models, Animal; Embryonic Stem Cells; Female; Hernias, Diaphragmatic, Congenital; Lung; Mice; Organ Size; Phenyl Ethers; Pregnancy; Teratogens | 2019 |
Decreased expression of GATA4 in the diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Down-Regulation; Female; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pleura; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2013 |
Pulmonary FGF-18 gene expression is downregulated during the canalicular-saccular stages in nitrofen-induced hypoplastic lungs.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Down-Regulation; Female; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Immunohistochemistry; Lung; Lung Diseases; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2013 |
Expression of Sproutys and SPREDs is decreased during lung branching morphogenesis in nitrofen-induced pulmonary hypoplasia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Immunohistochemistry; Lung; Lung Diseases; MAP Kinase Signaling System; Morphogenesis; Nerve Tissue Proteins; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Spatiotemporal alterations in Sprouty-2 expression and tyrosine phosphorylation in nitrofen-induced pulmonary hypoplasia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Nerve Tissue Proteins; Phenyl Ethers; Phosphotyrosine; Pregnancy; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; RNA, Messenger; Specific Pathogen-Free Organisms | 2013 |
Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Insulin-Like Growth Factor II; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Trophoblasts; Up-Regulation | 2014 |
Decreased apelin and apelin-receptor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Apelin; Apelin Receptors; Blotting, Western; Cell Survival; Disease Models, Animal; Female; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Intercellular Signaling Peptides and Proteins; Lung; Microscopy, Confocal; Phenyl Ethers; Pregnancy; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled; RNA, Messenger | 2014 |
VEGF receptor expression decreases during lung development in congenital diaphragmatic hernia induced by nitrofen.
Topics: Animals; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor | 2014 |
Amniotic fluid derived mesenchymal stromal cells augment fetal lung growth in a nitrofen explant model.
Topics: Amniotic Fluid; Animals; Disease Models, Animal; Female; Fetal Development; Lung; Mesenchymal Stem Cells; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2014 |
Increased uptake of dietary retinoids at the maternal-fetal barrier in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Chromatography, High Pressure Liquid; Dietary Supplements; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lipoproteins, LDL; Low Density Lipoprotein Receptor-Related Protein-1; Maternal-Fetal Exchange; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Retinoids | 2014 |
Upregulation of serotonin-receptor-2a and serotonin transporter expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Confocal; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Up-Regulation | 2014 |
Nitrofen increases total retinol levels in placenta during lung morphogenesis in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Morphogenesis; Olive Oil; Phenyl Ethers; Placenta; Plant Oils; Pregnancy; Rats; Rats, Sprague-Dawley; Retinol-Binding Proteins; Vitamin A | 2014 |
Myogenin gene expression is not altered in the developing diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Diaphragm; Disease Models, Animal; Female; Gene Expression; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Myogenin; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2014 |
Therapeutic potential of mesenchymal stem cell transplantation in a nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Mesenchymal Stem Cell Transplantation; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Treatment Outcome | 2014 |
Disruption of copper-dependent signaling pathway in the nitrofen-induced congenital diaphragmatic hernia.
Topics: Adenosine Triphosphatases; Animals; Cation Transport Proteins; Copper; Copper Transporter 1; Copper-Transporting ATPases; Disease Models, Animal; Female; Fetus; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA; Signal Transduction | 2015 |
Decidual β-carotene-15,15'-oxygenase-1 and 2 (BCMO1,2) expression is increased in nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; beta-Carotene 15,15'-Monooxygenase; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Fetus; Hernias, Diaphragmatic, Congenital; Immunoenzyme Techniques; Maternal-Fetal Exchange; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA | 2015 |
Prenatal administration of neuropeptide bombesin promotes lung development in a rat model of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Bombesin; Disease Models, Animal; Female; Fetal Therapies; Hernias, Diaphragmatic, Congenital; Lung; Neurotransmitter Agents; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2014 |
Antenatal use of bosentan and/or sildenafil attenuates pulmonary features in rats with congenital diaphragmatic hernia.
Topics: Animals; Bosentan; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Piperazines; Pregnancy; Purines; Random Allocation; Rats; Rats, Wistar; Sildenafil Citrate; Sulfonamides; Vascular Remodeling | 2014 |
Increased pulmonary RhoA expression in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; rhoA GTP-Binding Protein; RNA, Messenger | 2015 |
Defective parasympathetic innervation is associated with airway branching abnormalities in experimental CDH.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Disease Models, Animal; Embryo, Mammalian; Female; Hernias, Diaphragmatic, Congenital; Humans; Immunoenzyme Techniques; Lung; Mice; Parasympathetic Nervous System; Pesticides; Phenyl Ethers; Respiratory System; Stem Cells; Verapamil | 2015 |
Mesenchymal expression of the FRAS1/FREM2 gene unit is decreased in the developing fetal diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Fetal Development; Gene Expression; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Mesoderm; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2016 |
Possible role of increased oxidative stress in pulmonary hypertension in experimental diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Oxidative Stress; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2016 |
Upregulation of S1P1 and Rac1 receptors in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Gene Expression; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; Up-Regulation | 2016 |
Expression of hepatic lipid droplets is decreased in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Apoptosis; Disease Models, Animal; Hernias, Diaphragmatic, Congenital; Lipid Droplets; Liver; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2016 |
Antenatal retinoic acid administration increases trophoblastic retinol-binding protein dependent retinol transport in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Biological Transport; Disease Models, Animal; Female; Fetal Weight; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats; Retinol-Binding Proteins; Tretinoin; Trophoblasts; Vitamin A | 2016 |
Increased c-kit and stem cell factor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Microscopy, Confocal; Organogenesis; Phenyl Ethers; Pregnancy; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Stem Cell Factor | 2016 |
Antenatal Saireito (TJ-114) Can Improve Pulmonary Hypoplasia and Pulmonary Vascular Remodeling in Nitrofen-Induced Congenital Diaphragmatic Hernia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Dogs; Drugs, Chinese Herbal; Female; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2016 |
[Effects of Tetrandrine Prenatal Intervention on Alveolar Epithelial Cells Type I Differentiation in Rat Model of Nitrofen-induced Congenital Diaphragmatic Hernia].
Topics: Alveolar Epithelial Cells; Animals; Benzylisoquinolines; Cell Differentiation; Disease Models, Animal; Female; Fetus; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2016 |
Decreased expression of hepatocyte growth factor in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Embryonic Development; Female; Fetus; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hepatocyte Growth Factor; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2016 |
Decreased Desmin expression in the developing diaphragm of the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Desmin; Diaphragm; Disease Models, Animal; Female; Fetal Development; Fluorescent Antibody Technique; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2016 |
Downregulation of Forkhead box F1 gene expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Down-Regulation; Female; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Nerve Tissue Proteins; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2016 |
Expression of Prx1 and Tcf4 is decreased in the diaphragmatic muscle connective tissue of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Connective Tissue; Diaphragm; Disease Models, Animal; Down-Regulation; Gene Expression; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Homeodomain Proteins; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Teratogens; Transcription Factor 4; Transcription Factors | 2016 |
Decreased Endoglin expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Blotting, Western; Disease Models, Animal; Endoglin; Female; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Humans; Lung; Male; Microscopy, Confocal; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Expression of T-box transcription factors 2, 4 and 5 is decreased in the branching airway mesenchyme of nitrofen-induced hypoplastic lungs.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Lung; Lung Diseases; Mesoderm; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; T-Box Domain Proteins | 2017 |
Suppressed erythropoietin expression in a nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Erythropoietin; Female; Gene Expression Regulation, Developmental; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Tretinoin | 2017 |
Maternal administration of betamethasone inhibits proliferation induced by fetal tracheal occlusion in the nitrofen rat model for congenital diaphragmatic hernia: a placebo-controlled study.
Topics: Animals; Betamethasone; Disease Models, Animal; Female; Fetal Organ Maturity; Fetal Weight; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Ligation; Lung; Lung Diseases; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Surgical Instruments; Teratogens; Trachea | 2008 |
Early development of the primordial mammalian diaphragm and cellular mechanisms of nitrofen-induced congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Diaphragm; Disease Models, Animal; Embryo, Mammalian; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Maternal Exposure; Mice; NIH 3T3 Cells; Peritoneum; Pesticides; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2010 |
Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Hernia, Diaphragmatic; Immunohistochemistry; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Upregulation of endothelin receptors A and B in the nitrofen induced hypoplastic lung occurs early in gestation.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Up-Regulation | 2010 |
Prenatal retinoic acid up-regulates pulmonary gene expression of COUP-TFII, FOG2, and GATA4 in pulmonary hypoplasia.
Topics: Animals; COUP Transcription Factor II; Disease Models, Animal; DNA-Binding Proteins; Female; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Humans; Lung; Mice; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors; Tretinoin; Up-Regulation | 2009 |
Microscopic magnetic resonance in congenital diaphragmatic hernia and associated malformations in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Microscopy; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2010 |
Disturbance of parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Lung Diseases; Parathyroid Hormone-Related Protein; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
Up-regulation of Wnt5a gene expression in the nitrofen-induced hypoplastic lung.
Topics: Actins; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Mice; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Up-Regulation; Wnt Proteins; Wnt-5a Protein | 2009 |
Is there a role for antioxidants in prevention of pulmonary hypoplasia in nitrofen-induced rat model of congenital diaphragmatic hernia?
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Drug Synergism; Female; Fetus; Free Radical Scavengers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipid Peroxidation; Lung; Lung Diseases; Male; Maternal-Fetal Exchange; Pesticides; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E | 2010 |
Bronchopulmonary innervation defects in infants and rats with congenital diaphragmatic hernia.
Topics: Animals; Bronchi; Disease Models, Animal; Female; Glial Cell Line-Derived Neurotrophic Factor; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Immunoblotting; Immunohistochemistry; Lung; Neural Crest; Neuroglia; Phenyl Ethers; Pregnancy; Proto-Oncogene Proteins c-ret; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Trachea; Ubiquitin Thiolesterase | 2010 |
Spatiotemporal alteration in phosphatidylinositide 3-kinase-serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Fetal Diseases; Fetal Organ Maturity; Functional Laterality; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Mice; Morphogenesis; Phenyl Ethers; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors | 2010 |
Expression and function of phosphodiesterases in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hyperoxia; Phenyl Ethers; Phosphoric Diester Hydrolases; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Vasodilation | 2010 |
Antenatal steroid and tracheal occlusion restore vascular endothelial growth factor receptors in congenital diaphragmatic hernia rat model.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Sensitivity and Specificity; Steroids; Tracheal Stenosis | 2010 |
Insulinlike growth factor receptor type 1 and type 2 are downregulated in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia.
Topics: Animals; Disease Models, Animal; Female; Fetal Diseases; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Morphogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tretinoin; Up-Regulation | 2010 |
Gene expression analysis in hypoplastic lungs in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Genome-Wide Association Study; Hernia, Diaphragmatic; Humans; Infant, Newborn; Lung; Oligonucleotide Array Sequence Analysis; Persistent Fetal Circulation Syndrome; Phenyl Ethers; Rats | 2010 |
Prenatal treatment with retinoic acid activates parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Female; Lung; Lung Diseases; Olive Oil; Parathyroid Hormone-Related Protein; Phenyl Ethers; Plant Oils; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tretinoin; Up-Regulation | 2011 |
Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Fetal Development; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Morphogenesis; Oxidative Stress; Phenyl Ethers; Platelet-Derived Growth Factor; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Downregulation of FGFRL1 contributes to the development of the diaphragmatic defect in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rats; Receptor, Fibroblast Growth Factor, Type 1 | 2011 |
Connective tissue growth factor expression pattern in lung development.
Topics: Abnormalities, Drug-Induced; Animals; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fetal Development; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Ligation; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trachea | 2010 |
Embryonic Wnt gene expression in the nitrofen-induced hypoplastic lung using 3-dimensional imaging.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Imaging, Three-Dimensional; In Situ Hybridization; Lung; Mice; Phenyl Ethers; Pregnancy; Pregnancy, Animal; RNA; Tomography, Optical; Wnt Proteins; Wnt2 Protein | 2010 |
Effect of insulin-like growth factors on lung development in a nitrofen-induced CDH rat model.
Topics: Actins; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Membrane Glycoproteins; Nuclear Proteins; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatomedins; Thyroid Nuclear Factor 1; Tissue Culture Techniques; Transcription Factors | 2011 |
Down-regulation of lung Kruppel-like factor in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Developmental; Kruppel-Like Transcription Factors; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2011 |
Expression of the Wilm's tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Genes, Wilms Tumor; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2011 |
[Effect of ambroxol on lung development of rat models with nitrofen-induced congenital diaphragmatic hernia].
Topics: Ambroxol; Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2010 |
The role of primary myogenic regulatory factors in the developing diaphragmatic muscle in the nitrofen-induced diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Diaphragm; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; MyoD Protein; Myogenic Regulatory Factor 5; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2011 |
Prenatal administration of retinoic acid upregulates connective tissue growth factor in the nitrofen CDH model.
Topics: Animals; Connective Tissue Growth Factor; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2011 |
Prenatal administration of retinoic acid upregulates insulin-like growth factor receptors in the nitrofen-induced hypoplastic lung.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2011 |
Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
Topics: Animals; Body Weight; Brain; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Nitric Oxide; Phenyl Ethers; Phosphodiesterase 5 Inhibitors; Piperazines; Pregnancy; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones | 2011 |
Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?
Topics: Animals; Carbohydrate Conformation; Disease Models, Animal; Epigenomics; Epitopes; Female; Fibroblast Growth Factors; Heparitin Sulfate; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Mice; Molecular Sequence Data; Morphogenesis; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2011 |
Upregulation of fibroblast growth factor receptor 2 and 3 in the late stages of fetal lung development in the nitrofen rat model.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; RNA, Messenger; Up-Regulation | 2012 |
Nitrofen interferes with trophoblastic expression of retinol-binding protein and transthyretin during lung morphogenesis in the nitrofen-induced congenital diaphragmatic hernia model.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Morphogenesis; Phenyl Ethers; Prealbumin; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Retinol-Binding Proteins; RNA; Trophoblasts | 2012 |
A longer tracheal occlusion period results in increased lung growth in the nitrofen rat model.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Female; Fetal Diseases; Fetus; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Time Factors; Trachea | 2012 |
Prenatal retinoic acid upregulates connexin 43 (Cx43) gene expression in pulmonary hypoplasia in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Cell Differentiation; Connexin 43; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelial Cells; Female; Fetal Therapies; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Intraperitoneal; Lung; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2012 |
Antenatal imatinib treatment reduces pulmonary vascular remodeling in a rat model of congenital diaphragmatic hernia.
Topics: Airway Remodeling; Animals; Apoptosis; Benzamides; Caspase 3; Cell Proliferation; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imatinib Mesylate; Ki-67 Antigen; Lung; Phenyl Ethers; Piperazines; Platelet-Derived Growth Factor; Pregnancy; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; RNA, Messenger | 2012 |
ANG-1 TIE-2 and BMPR signalling defects are not seen in the nitrofen model of pulmonary hypertension and congenital diaphragmatic hernia.
Topics: Angiopoietin-1; Animals; Animals, Newborn; Bone Morphogenetic Protein Receptors; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenyl Ethers; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Signal Transduction; Smad1 Protein; Smad5 Protein; Smad8 Protein | 2012 |
Alterations of peroxisome proliferator-activated receptor γ and monocyte chemoattractant protein 1 gene expression in the nitrofen-induced hypoplastic lung.
Topics: Animals; Biomarkers; Chemokine CCL2; Disease Models, Animal; Down-Regulation; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; PPAR gamma; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2012 |
Prenatal retinoic acid improves lung vascularization and VEGF expression in CDH rat.
Topics: Analysis of Variance; Angiogenesis Inducing Agents; Animals; Arterioles; Biomarkers; Blotting, Western; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Treatment Outcome; Tretinoin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Increased trophoblastic apoptosis mediated by neutrophil gelatinase-associated lipocalin (NGAL) activation in the nitrofen model of congenital diaphragmatic hernia.
Topics: Acute-Phase Proteins; Animals; Apoptosis; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipocalin-2; Lipocalins; Phenyl Ethers; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Trophoblasts | 2013 |
Decreased pulmonary c-Cbl expression and tyrosine phosphorylation in the nitrofen-induced rat model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Phosphorylation; Proto-Oncogene Proteins c-cbl; Rats; Rats, Sprague-Dawley; Tyrosine | 2013 |
Effect of nitrofen in the final stages of development of the diaphragm muscle in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Myosins; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2013 |
Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse.
Topics: Animals; Biomarkers; Disease Models, Animal; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Mice; Organ Culture Techniques; Phenyl Ethers; RNA, Messenger | 2002 |
Embryological origins and development of the rat diaphragm.
Topics: Animals; Cell Division; Cell Movement; Diaphragm; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Mice; Muscle Development; Muscle Fibers, Skeletal; Phenyl Ethers; Phrenic Nerve; Proto-Oncogene Proteins c-met; Rats; Respiratory System Abnormalities; Stem Cells | 2003 |
Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Airway Obstruction; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Isoenzymes; Membrane Proteins; Muscle, Smooth; Pesticides; Phenyl Ethers; Potassium Chloride; Pregnancy; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
The activation of the retinoic acid response element is inhibited in an animal model of congenital diaphragmatic hernia.
Topics: Animals; beta-Galactosidase; Disease Models, Animal; Drug Interactions; Gene Expression; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; In Vitro Techniques; Lac Operon; Mice; Phenyl Ethers; Response Elements; Teratogens; Tretinoin | 2003 |
The adrenal cortex in experimental congenital diaphragmatic hernia.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; DNA; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2003 |
Expression and activity of matrix metallo proteinases 2 and 9 and their inhibitors in rat lungs during the perinatal period and in diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; DNA Primers; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Organogenesis; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2003 |
Pulmonary surfactant protein A, B, and C mRNA and protein expression in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Disease Models, Animal; Embryo, Mammalian; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; In Situ Hybridization; Infant, Newborn; Lung; Phenyl Ethers; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Rats; Rats, Wistar; RNA, Messenger | 2003 |
Nitrofen-induced congenital diaphragmatic hernia in rat embryo: what model?
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Liver; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Effect of epidermal growth factor on pulmonary hypoplasia in experimental diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Epidermal Growth Factor; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Electron; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2004 |
Reductions in the incidence of nitrofen-induced diaphragmatic hernia by vitamin A and retinoic acid.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Hernia, Diaphragmatic; Incidence; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Tretinoin; Vitamin A | 2004 |
Pulmonary elastin expression is decreased in the nitrofen-induced rat model of congenital diaphragmatic hernia.
Topics: Animals; Desmosine; Disease Models, Animal; Elastin; Female; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Diaphragm; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation, Developmental; Genes, Reporter; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Heterozygote; Lac Operon; Mice; Mice, Transgenic; Morphogenesis; Phenyl Ethers; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein B; Vascular Endothelial Growth Factor A | 2004 |
The relationship of diaphragmatic defect, liver growth, and lung hypoplasia in nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Body Weight; Diaphragm; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Image Processing, Computer-Assisted; Liver; Lung; Microscopy, Electron, Scanning; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Thorax; Video Recording | 2004 |
Altered expression of angiotensin II receptor subtypes and transforming growth factor-beta in the heart of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Heart; Herbicides; Hernia, Diaphragmatic; Maternal Exposure; Myocardium; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Transforming Growth Factor beta | 2005 |
Pax3 mRNA is decreased in the hearts of rats with experimental diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; DNA-Binding Proteins; Female; Gene Expression Regulation, Developmental; Heart; Herbicides; Hernia, Diaphragmatic; Maternal Exposure; Myocardium; Paired Box Transcription Factors; PAX3 Transcription Factor; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2005 |
Expression of vasoactive mediators during mechanical ventilation in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelin-1; Female; Gene Expression Regulation, Developmental; Herbicides; Hernia, Diaphragmatic; Lung; Maternal Exposure; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Circulation; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Resistance; Vasoconstriction; Vasodilation | 2005 |
Insulinlike growth factor I gene expression is increased in the fetal lung after tracheal ligation.
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fetal Proteins; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hyperplasia; Insulin-Like Growth Factor I; Ligation; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Somatotropin; RNA, Messenger; Thioredoxins; Trachea | 2005 |
Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Olive Oil; Phenyl Ethers; Plant Oils; Pregnancy; Rats; Rats, Wistar; Vitamin A; Vitamins | 2005 |
Effect of nitric oxide on the development of nitrofen-induced fetal hypoplastic lung explants.
Topics: Animals; Disease Models, Animal; Female; Fetal Organ Maturity; In Vitro Techniques; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Teratogens | 2005 |
Effects of prenatal vitamins A, E, and C on the hypoplastic hearts of fetal rats with diaphragmatic hernia.
Topics: Animals; Apoptosis; Ascorbic Acid; Disease Models, Animal; DNA; Female; Fetal Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; In Situ Nick-End Labeling; Oxidants; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Vitamin A; Vitamin E; Vitamins | 2005 |
Nitrovasodilator responses in pulmonary arterioles from rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Atrial Natriuretic Factor; Cyclic GMP; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Nitric Oxide; Nitroprusside; Pesticides; Phenyl Ethers; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2005 |
Expression of Connexin 43 in the hearts of rat embryos exposed to nitrofen and effects of vitamin A on it.
Topics: Abnormalities, Multiple; Analysis of Variance; Animals; Connexin 43; Disease Models, Animal; Female; Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Neural Crest; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Vitamin A | 2006 |
Sex and congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Disorders of Sex Development; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Male; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Differentiation | 2006 |
Improvement of pulmonary hypoplasia associated with congenital diaphragmatic hernia by in utero CFTR gene therapy.
Topics: Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Fetal Diseases; Genetic Therapy; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2006 |
Connexin 43 gene expression in mice with cardiopulmonary developmental defects.
Topics: Animals; Cell Differentiation; Cell Proliferation; Connexin 43; Craniofacial Abnormalities; Disease Models, Animal; Down-Regulation; Gene Expression Profiling; Heart Defects, Congenital; Humans; Lung; Mice; Pesticides; Phenyl Ethers; Pulmonary Artery; Regional Blood Flow; Up-Regulation | 2006 |
Myocardium expression of connexin 43, SERCA2a, and myosin heavy chain isoforms are preserved in nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Calcium-Transporting ATPases; Connexin 43; Disease Models, Animal; Female; Fetal Organ Maturity; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Myocardium; Myosin Heavy Chains; Pesticides; Phenyl Ethers; Pregnancy; Protein Isoforms; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2006 |
Altered regulation of retinoic acid synthesis in nitrofen-induced hypoplastic lung.
Topics: Acyltransferases; Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Developmental; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Olive Oil; Phenyl Ethers; Plant Oils; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Retinal Dehydrogenase; Retinoic Acid 4-Hydroxylase; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2007 |
Disturbance of retinol transportation causes nitrofen-induced hypoplastic lung.
Topics: Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Hernia, Diaphragmatic; Lung; Lung Diseases; Morphogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Signal Transduction; Vitamin A | 2007 |
Reduced expression of aquaporin 5 water channel in nitrofen-induced hypoplastic lung with congenital diaphragmatic hernia rat model.
Topics: Animals; Animals, Newborn; Aquaporin 5; Disease Models, Animal; Down-Regulation; Female; Fetus; Gene Expression Regulation; Genetic Markers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Male; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Statistics, Nonparametric | 2007 |
Down-regulation of Wnt signal pathway in nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Embryo, Nonmammalian; Female; GATA6 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Signal Transduction | 2007 |
Vitamin A deficiency (VAD), teratogenic, and surgical models of congenital diaphragmatic hernia (CDH).
Topics: Animals; Diaphragm; Disease Models, Animal; Dogs; Hernia, Diaphragmatic; Lung; Models, Animal; Phenyl Ethers; Rabbits; Rats; Sheep; Signal Transduction; Species Specificity; Teratogens; Tretinoin; Vitamin A; Vitamin A Deficiency | 2007 |
[Effect of tetrandrine on endothelin expression in the lungs and clinical significance thereof: experiment with rat models with nitrofen-induced congenital diaphragmatic hernia].
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Disease Models, Animal; Endothelins; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2007 |
The effect of tracheal occlusion on lung branching in the rat nitrofen CDH model.
Topics: Animals; Body Weight; Bronchi; Cell Proliferation; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Size; Pesticides; Phenyl Ethers; Pregnancy; Rats; Trachea | 2008 |
[Effect of tetrandrine on lung development: experiment of nitrofen-induced congenital diaphragmatic hernia fetal rat model].
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Electron; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Down-Regulation; Female; GATA4 Transcription Factor; GATA6 Transcription Factor; Gene Expression Regulation, Developmental; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity | 2008 |
Prenatal treatment with retinoic acid accelerates type 1 alveolar cell proliferation of the hypoplastic lung in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Drug Administration Schedule; Epithelial Cells; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Prenatal Care; Probability; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiratory System Abnormalities; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Tretinoin | 2008 |
Prenatal treatment with retinoic acid promotes pulmonary alveologenesis in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Fetal Organ Maturity; Hernias, Diaphragmatic, Congenital; Injections, Intraperitoneal; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Prenatal Care; Probability; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiratory System Abnormalities; Sensitivity and Specificity; Tretinoin | 2008 |
Intrinsic catch-up growth of hypoplastic fetal lungs is mediated by interleukin-6.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Interleukin-6; Lung; Lung Diseases; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Nitrofen-induced diaphragmatic hernias in rats: an animal model.
Topics: Animals; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rabbits; Rats | 1993 |
Lung growth and maturation in the rat model of experimentally induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Pulmonary Surfactants; Rats; Rats, Wistar | 1993 |
Prenatal hormonal therapy improves pulmonary compliance in the nitrofen-induced CDH rat model.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Prenatal Care; Rats | 1996 |
Decreased pulmonary nitric oxide synthase activity in the rat model of congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 1996 |
Embryology of congenital diaphragmatic hernia.
Topics: Animals; Cell Differentiation; Diaphragm; Disease Models, Animal; Epithelial Cells; Epithelium; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Rats | 1996 |
Nitrofen dose-dependent gestational day-specific murine lung hypoplasia and left-sided diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fetus; Gestational Age; Hernia, Diaphragmatic; Lung; Mice; Mice, Inbred Strains; Microscopy, Electron; Phenyl Ethers | 1997 |
Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar; Thyrotropin; Thyroxine; Triiodothyronine | 1997 |
Administration of antenatal glucocorticoids prevents pulmonary artery structural changes in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Female; Fetal Diseases; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Image Processing, Computer-Assisted; Immunohistochemistry; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 1998 |
Endothelin-1 pulmonary vasoconstriction in rats with diaphragmatic hernia.
Topics: Animals; Arterioles; Disease Models, Animal; Endothelin-1; Female; Herbicides; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Hypoxic pulmonary vasoconstriction is impaired in rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Disease Models, Animal; Female; Fetus; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypoxia; Phenyl Ethers; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Pulmonary arterioles from rats with congenital diaphragmatic hernias are hypoplastic but not hyperresponsive.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Phenylephrine; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Heart hypoplasia in experimental congenital diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Female; Heart; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Myocardium; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens | 1999 |
Increased tropoelastin and procollagen expression in the lung of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Teratogens; Tropoelastin | 1999 |
Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Body Weight; Disease Models, Animal; DNA; Female; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Histocytochemistry; Lung; Organ Size; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Trachea; Tracheal Stenosis | 1999 |
Skeletal malformations associated with congenital diaphragmatic hernia: experimental and human studies.
Topics: Animals; Bone and Bones; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Phenyl Ethers; Pregnancy; Radiography; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Retrospective Studies; Ribs; Spine | 1999 |
Nitrofen-induced congenital malformations of the heart and great vessels in rats: an animal model.
Topics: Animals; Coronary Vessel Anomalies; Disease Models, Animal; Female; Gestational Age; Heart Defects, Congenital; Heart Septal Defects, Ventricular; Herbicides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Antenatal dexamethasone enhances endothelin receptorB expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Endothelin-1; Female; Glucocorticoids; Herbicides; Hernia, Diaphragmatic; Hypertension, Pulmonary; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Effect of CGS 26303, an endothelin-converting enzyme-neutral endopeptidase inhibitor, on nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Body Weight; Disease Models, Animal; Endothelin-Converting Enzymes; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Subcutaneous; Linear Models; Liver; Lung; Metalloendopeptidases; Organ Size; Organophosphonates; Phenyl Ethers; Pregnancy; Proportional Hazards Models; Protease Inhibitors; Rats; Reference Values; Survival Analysis; Tetrazoles | 2000 |
Antenatal dexamethasone administration inhibits smooth-muscle-cell DNA synthesis in pulmonary-arterial media in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bromodeoxyuridine; Dexamethasone; Disease Models, Animal; DNA; Drug Evaluation, Preclinical; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Immunohistochemistry; Phenyl Ethers; Pregnancy; Prenatal Care; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tunica Media | 2000 |
Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development.
Topics: Animals; Cell Division; Disease Models, Animal; Endothelial Growth Factors; Extracellular Matrix Proteins; Female; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lymphokines; Microscopy, Electron; Peptides; Pesticides; Phenyl Ethers; Pregnancy; Protein Precursors; Proteolipids; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2000 |
BAPS prize-1999: Lung growth induced by prenatal tracheal occlusion and its modifying factors: a study in the rat model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Lung; Maternal-Fetal Exchange; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Terbutaline; Tocolytic Agents; Trachea | 2001 |
Impaired spreading of surfactant phospholipids in the lungs of newborn rats with pulmonary hypoplasia as a model of congenital diaphragmatic hernia induced by nitrofen.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Blotting, Western; Body Weight; Chromatography, Thin Layer; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Organ Size; Phenyl Ethers; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Sphingomyelins | 2001 |
Oxygen-induced vasodilation is blunted in pulmonary arterioles from fetal rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Culture Techniques; Disease Models, Animal; Female; Hernia, Hiatal; Hypertension, Pulmonary; Oxygen; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Probability; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reference Values; Risk Assessment; Sensitivity and Specificity; Vasodilation | 2001 |
Structural immaturity of the heart in congenital diaphragmatic hernia in rats.
Topics: Abnormalities, Multiple; Actins; Animals; Disease Models, Animal; Elastin; Enzyme-Linked Immunosorbent Assay; Fetal Organ Maturity; Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Procollagen; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tropoelastin | 2001 |
Gene expression of insulin-like growth factor-1 and epidermal growth factor is downregulated in the heart of rats with nitrofen-induced diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Epidermal Growth Factor; Female; Fetal Diseases; Gene Expression; Heart; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Insulin-Like Growth Factor I; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Neural crest-derived defects in experimental congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Neural Crest; Parathyroid Glands; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Thymus Gland; Thyroid Gland | 2001 |
Cardiac gene expression and synthesis of atrial natriuretic peptide in the nitrofen model of congenital diaphragmatic hernia in rats: effect of prenatal dexamethazone treatment.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Dexamethasone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glucocorticoids; Herbicides; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Myocardium; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Restoring effects of vitamin A on surfactant synthesis in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Analysis of Variance; Animals; Blotting, Northern; Chromatography, Thin Layer; Disease Models, Animal; DNA; Female; Fetus; Fluorescent Antibody Technique; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Phenyl Ethers; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats; Rats, Wistar; RNA, Messenger; Vitamin A | 2001 |
Effect of prenatal tetrandrine therapy on pulmonary vascular structural remodeling in the nitrofen-induced CDH rat model.
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2000 |
The kidney in the fetal rat model of congenital diaphragmatic hernia induced by nitrofen.
Topics: Abnormalities, Drug-Induced; Animals; Diaphragm; Disease Models, Animal; Female; Herbicides; Hernia, Diaphragmatic; Kidney; Lung; Phenyl Ethers; Pregnancy; Rats | 1992 |
Nitrofen-induced diaphragmatic hernias in rats: pulmonary antioxidant enzyme activities.
Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Disease Models, Animal; Female; Glutathione Peroxidase; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Maternal-Fetal Exchange; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Superoxide Dismutase | 1992 |
Nitrofen-induced diaphragmatic hernias in rats: an animal model.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Incidence; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Inbred Strains; Regression Analysis | 1990 |