nitrofen has been researched along with Diaphragmatic Hernia in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.03) | 18.7374 |
| 1990's | 38 (19.49) | 18.2507 |
| 2000's | 100 (51.28) | 29.6817 |
| 2010's | 55 (28.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dingemann, J; Doi, T; Gosemann, JH; Nakazawa, N; Puri, P; Ruttenstock, EM | 1 |
| Alvarez, LA; Corcionivoschi, N; Friedmacher, F; Fujiwara, N; Gosemann, JH; Puri, P | 2 |
| Dewachter, C; Dewachter, L; Makanga, M; Maruyama, H; Naeije, R; Rondelet, B; Vuckovic, A | 1 |
| Miniati, D; Schecter, S; Shue, E; Wu, J | 1 |
| Friedmacher, F; Fujiwara, N; Hofmann, A; Puri, P; Takahashi, H | 1 |
| Duess, JW; Friedmacher, F; Kutasy, B; Puri, P | 1 |
| Friedmacher, F; Gosemann, JH; Hofmann, AD; Hunziker, M; Puri, P; Takahashi, H | 1 |
| Aperia, A; Eklöf, AC; Frenckner, B; Ringman, A; Zelenina, M | 1 |
| Deprest, JA; Klaritsch, P; Mayer, S; Sbragia, L; Till, H; Toelen, J | 1 |
| Chen, Z; Ji, Y; Liu, W; Wang, Y; Xiong, Z; Xu, C | 1 |
| Aperia, A; Eklöf, AC; Frenckner, B; Ringman Uggla, A; Zelenina, M | 1 |
| Clugston, RD; Greer, JJ; Zhang, W | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, E | 8 |
| Doi, T; Puri, P; Sugimoto, K | 1 |
| Aras, R; Bret, M; Cuesta, E; Luis, AL; Martinez, L; Pederiva, F; Tovar, JA | 1 |
| Dingemann, J; Doi, T; Lukosiūte, A; Puri, P; Ruttenstock, E | 2 |
| Doi, T; Hajduk, P; Puri, P | 1 |
| Doi, T; Puri, P | 1 |
| Celik, Y; Cigdem, MK; Kizil, G; Kizil, M; Nergiz, Y; Onen, A | 1 |
| Lopez, RA; Martinez, L; Pederiva, F; Rodriguez, JI; Tovar, JA | 1 |
| Eaton, F; Morgan, B; Reiss, I; Thébaud, B; Tibboel, D; van der Horst, IW | 1 |
| Al-Abbad, S; Baird, R; Grushka, JR; Kaplan, F; Laberge, JM; Puligandla, P | 1 |
| Farmer, D; Gonçalves, FL; Nassr, AC; Pereira, LA; Sbragia, L; Schmidt, AF | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, E; Sugimoto, K | 1 |
| Burgos, CM; Eklöf, AC; Fagerström-Billai, F; Frenckner, B; Nord, M; Uggla, AR | 1 |
| Dingemann, J; Doi, T; Puri, P; Ruttenstock, EM | 4 |
| Burgos, CM; Didon, L; Eklöf, AC; Frenckner, B; Nord, M; Roos, A | 1 |
| Doi, T; Murphy, P; Puri, P; Sato, H; Takayasu, H | 1 |
| Esumi, G; Kinoshita, Y; Masumoto, K; Nagata, K; Nonaka, K; Taguchi, T; Teshiba, R; Yamaza, H | 1 |
| Chen, G; Chen, L; Qiao, YL; Xiao, XM; Zheng, S | 1 |
| Chen, G; Chen, L; Qiao, Y; Xiao, X; Zheng, S | 1 |
| Archer, SL; Dyck, JR; Eaton, F; Gilmour, G; Gressens, P; Kassiri, Z; Koonen, D; Luong, C; Morgan, B; Nadeem, K; Rey-Perra, J; Sauve, Y; Thébaud, B; Todd, KG; Vadivel, A; Walker, D | 1 |
| Connell, MG; Fernig, DG; Jesudason, EC; Losty, PD; Thompson, SM; Turnbull, JE; van Kuppevelt, TH; Xu, R | 1 |
| Kluth, D; Mayer, S; Metzger, R | 1 |
| Dingemann, J; Doi, T; Gosemann, JH; Puri, P; Ruttenstock, EM | 1 |
| Martinez, L; Pederiva, F; Tovar, JA | 1 |
| Doi, T; Friedmacher, F; Fujiwara, N; Gosemann, JH; Kutasy, B; Puri, P | 2 |
| Beck, V; Davey, MG; Deckx, S; Deprest, JA; Froyen, G; Klaritsch, P; Mayer, S; Petersen, SG; Roubliova, XI | 1 |
| Fox, EK; Huang, Z; Keijzer, R; Post, M; Tibboel, D; Tseu, I; van Loenhout, RB | 1 |
| Galambos, C; Gittes, GK; Lath, NR; Malek, M; Potoka, DA; Rocha, AB | 1 |
| Chang, YT; Eklöf, AC; Frenckner, B; Hedin, U; Lengquist, M; Osterholm, C; Ringman Uggla, A; Tran, PK; Tran-Lundmark, K | 1 |
| Connell, MG; Corbett, HJ; Fernig, DG; Jesudason, EC; Losty, PD | 1 |
| Dingemann, J; Doi, T; Friedmacher, F; Gosemann, JH; Kutasy, B; Puri, P | 2 |
| Gallindo, RM; Gonçalves, FL; Regis, AC; Sbragia, L; Schmidt, AF | 1 |
| Duess, JW; Gosemann, JH; Kutasy, B; Puri, P | 1 |
| Corcionivoschi, N; Friedmacher, F; Gosemann, JH; Puri, P; Takahashi, H | 1 |
| Hayakawa, M; Kikkawa, F; Kotani, T; Mano, Y; Sato, Y; Sumigama, S; Tsuda, H; Watanabe, Y | 1 |
| Figueira, RL; Gallindo, RM; Gonçalves, FL; Oliveira, FS; Pereira, LA; Sbragia, L; Schmidt, AF | 1 |
| Anderson, KD; Leinwand, MJ; Tefft, JD; Warburton, D; Zhao, J | 1 |
| Guarino, N; Oue, T; Puri, P; Shima, H; Teramoto, H | 1 |
| Anderson, KD; Coleman, C; Leinwand, MJ; Tefft, JD; Warburton, D; Zhao, J | 1 |
| Jesudason, EC | 1 |
| Guarino, N; Puri, P | 1 |
| Allan, DW; Babiuk, RP; Clugston, R; Greer, JJ; Zhang, W | 1 |
| Belik, J; Davidge, ST; Greer, JJ; Pan, J; Zhang, W | 1 |
| Bavik, C; Chen, MH; Greer, JJ; MacGowan, A; Ward, S | 1 |
| Diez-Pardo, JA; Gonzalez-Reyes, S; Martínez, I; Martínez, L; Rodriguez, JI; Rodriguez-Matas, MJ; Tovar, JA | 1 |
| Hisanaga, M; Kanehiro, H; Nakajima, Y; Tatekawa, Y | 1 |
| Balcerazak, D; Baracos, VE; Cheung, PY; Dixon, WT; Greer, JJ; Kobayashi, K; Lemke, RP; Schwingshackl, A; Zhang, W | 1 |
| Guarino, N; Puri, P; Sakai, M; Shima, H; Unemoto, K | 1 |
| Puri, P; Teramoto, H; Yoneda, A | 1 |
| Alvarez, L; Diez-Pardo, JA; Gonzalez-Reyes, S; Tovar, JA | 1 |
| Blommaart, Pj; Keijzer, R; Lamers, WH; Ruijter, J; Tibboel, D; Van Tuyl, M; Wert, SE | 1 |
| Baptista, MJ; Correia-Pinto, J; Estevão-Costa, J; Flake, AW; Leite-Moreira, AF; Pedrosa, C | 1 |
| Baglaj, SM; Czernik, J | 1 |
| Hu, T; Jiang, X; Li, J; Liu, W; Xiang, B | 1 |
| Babiuk, RP; Greer, JJ; Thébaud, B | 1 |
| Burgos, E; González-Reyes, S; Martínez, L; Tovar, JA | 1 |
| Heintz, CK; Mychaliska, GB; Officer, SM; Pierce, RA; Starcher, BC | 1 |
| Andreoli, S; Chang, R; D'Amore, PA; Ng, YS; Smith, SR; Truong, T; Wilson, J | 1 |
| Alaamian, M; Beshir, I; Fiegel, HC; Izbicki, JR; Kluth, D; Langwieler, T; Mann, O | 1 |
| Puri, P; Shinkai, M; Teramoto, H | 1 |
| Beckman, DL; Cummings, JJ; Katwa, LC; Whitehurst, ME | 1 |
| Fernandez-Dumont, V; Gonzalez-Reyes, S; Hernandez, F; Martinez, L; Martinez-Calonge, W; Tovar, J | 1 |
| Asato, Y; Ohta, T; Oshiro, T; Sakanashi, M; Sugahara, K | 1 |
| Puri, P; Shima, H; Shinkai, T; Solari, V | 1 |
| Chapin, CJ; Ertsey, R; Greer, JJ; Hara, A; Kitterman, JA; Sbragia, L; Yoshizawa, J | 1 |
| Eklöf, AC; Eriksson, H; Frenckner, B; Masironi, B; Sahlin, L | 1 |
| Areias, JC; Baptista, MJ; Correia-Pinto, J; Estevão-Costa, J; Flake, AW; Gonzaga, S; Leite-Moreira, AF; Melo-Rocha, G; Pedrosa, C; Teles, A | 1 |
| González-Reyes, S; Martínez, L; Tovar, JA | 1 |
| Beard, LL; Chapin, CJ; Ertsey, R; Folkesson, HG; Kitterman, JA; Matthay, MA | 1 |
| Coppola, CP; Gosche, JR; Hults, C; Vukcevic, Z | 1 |
| Calonge, WM; Fernandez-Dumont, V; Gonzalez-Reyes, S; Martinez, L; Tovar, JA | 2 |
| Chertin, B; Montedonico, S; Nakazawa, N; Puri, P; Shima, H | 1 |
| Connell, MG; Corbett, HJ; Jesudason, EC; Losty, PD; Purvis, A | 1 |
| Burgos, E; Fernández-Dumont, V; González-Reyes, S; Hernández, F; Martínez, L; Martínez-Calonge, W; Tovar, JA | 1 |
| Cohen, JC; Larson, JE | 1 |
| Baptista, MJ; Bastos, P; Correia-Pinto, J; De Krijger, RR; Gonzaga, S; Henriques-Coelho, T; Leite-Moreira, AF; Melo-Rocha, G; Nogueira-Silva, C; Roncon-Albuquerque, R; Roriz, JM; Rottier, R; Santos, M; Tibboel, D | 1 |
| Burdyga, TV; Connell, MG; Featherstone, NC; Fernig, DG; Jesudason, EC; Losty, PD; Wray, S | 1 |
| Calonge, WM; De Ceano-Vivas, M; Fernández-Dumont, V; González-Reyes, S; Martínez, L; Rodríguez, JI; Ruiz, E; Tovar, JA | 1 |
| Fernandez-Dumont, V; Gonzalez-Reyes, S; Martinez, L; Martinez-Calonge, W; Tovar, JA | 1 |
| Areias, JC; Baptista, MJ; Correia-Pinto, J; Gonzaga, S; Leite-Moreira, A; Melo-Rocha, G; Nogueira-Silva, C; Recamán, M; Roriz, JM; Santos, M; Soares-Fernandes, J | 1 |
| Blommaart, PE; DE Krijger, RR; Keijzer, R; Lamers, WH; Rajatapiti, P; Rottier, R; Tibboel, D; Visser, TJ | 1 |
| Montedonico, S; Nakazawa, N; Puri, P; Takayasu, H | 3 |
| Bannigan, J; Montedonico, S; Nakazawa, N; Puri, P; Shinkai, T | 1 |
| Montedonico, S; Nakazawa, N; Puri, P; Sato, H; Sugimoto, K; Takayasu, H | 1 |
| Montedonico, S; Nakazawa, N; Paradisi, F; Puri, P; Takayasu, H | 1 |
| Kling, DE; Schnitzer, JJ | 1 |
| Chen, ZX; Liu, WY; Wang, YG; Xiong, ZX; Xu, C | 1 |
| Correia-Pinto, J; Gonzaga, S; Moura, RS; Nogueira-Silva, C; Ohlmeier, S; Santos, M | 1 |
| Baptista, MJ; Correia-Pinto, J; Moura, RS; Nogueira-Silva, C; Santos, M; Soares-Fernandes, J | 1 |
| Babiuk, RP; Blomhoff, R; Clugston, RD; Greer, JJ; Gundersen, TE; Kawaguchi, R; Noble, BR; Sun, H; Underhill, TM; Walfish, PG | 1 |
| Lin, H; Liu, W; Tang, Y; Wang, Y; Xiong, Z | 1 |
| Anselmo, M; Baird, R; Flageole, H; Khan, N; Laberge, JM; Puligandla, P | 1 |
| Cheng, ZX; Liu, WY; Wang, YX; Xiong, ZX; Xu, C | 1 |
| Puri, P; Sato, H; Sugimoto, K; Takayasu, H | 1 |
| Montedonico, S; Nakazawa, N; Puri, P; Sugimoto, K; Takayasu, H | 1 |
| Areias, JC; Baptista, MJ; Correia-Pinto, J; Nogueira-Silva, C | 1 |
| Correia-Pinto, J; Esteves, N; Gonzaga, S; Moura, RS; Nogueira-Silva, C | 1 |
| Bloch, KD; Donahoe, PK; Suen, HC | 1 |
| Alles, AJ; Donahoe, PK; Losty, PD; Manganaro, TF; Schnitzer, JJ | 1 |
| Moya, FR; Mysore, MR; North, AJ; Shaul, PW; Thomas, VL; Wells, LB; Wu, LC | 1 |
| Donahoe, PK; Losty, PD; Manganaro, TF; Schnitzer, JJ; Suen, HC | 1 |
| Glick, PL; Holm, BA; Karamanoukian, H; Wilcox, DT | 1 |
| Aldazabal, P; Alfonso, LF; Lopez de Torre, B; Tovar, JA; Vilanova, J | 1 |
| Glick, PL; Karamanoukian, HL; O'Toole, SJ | 1 |
| Baoquan, Q; Diez-Pardo, JA; Tovar, JA | 1 |
| Abdel-Rahman, E; Azizkhan, RG; Dandonna, P; Glick, PL; Karamanoukian, HL; Love, JE; Peay, T | 1 |
| Hertl, M; Keijzer, R; Kluth, D; Tibboel, D | 1 |
| Chinoy, MR; Cilley, RE; Krummel, TM; Zgleszewski, SE | 1 |
| Albert, A; De Jongste, JC; Donahoe, PK; Ijsselstijn, H; Pacheco, BA; Schnitzer, JJ; Sluiter, W; Tibboel, D | 1 |
| Allan, DW; Greer, JJ | 1 |
| Gosney, JR; Lloyd, DA; Losty, PD; Okoye, BO | 2 |
| McCune, SK; Okazaki, T; Sharma, HS; Tibboel, D | 1 |
| Fisher, MJ; Hughes, AT; Lloyd, DA; Losty, PD; Okoye, BO | 1 |
| Anderson, KD; Buckley, S; Coleman, C; Gupta, M; Minoo, P; Tefft, JD; Warburton, D; Wuenschell, CW; Zhao, J | 1 |
| Miyazaki, E; Ohshiro, K; Puri, P; Taira, Y; Yamataka, T | 1 |
| Fisher, MJ; Lloyd, DA; Losty, PD; Okoye, BO; Wilmott, I | 1 |
| Au-Fliegner, M; Coppola, CP; Gosche, JR; Newell, MA | 1 |
| Au-Fliegner, M; Gosche, JR; Salami, S | 1 |
| Causak, RA; Chinoy, MR; Cilley, RE; Krummel, TM; Zgleszewski, SE; Zhang, L | 1 |
| Alfonso, LF; Alvarez, JI; Arnaiz, A; Diez-Pardo, JA; Migliazza, L; Tovar, JA; Xia, H | 1 |
| Miyazaki, E; Oue, T; Puri, P; Shima, H; Taira, Y | 3 |
| Diez-Pardo, JA; Migliazza, L; Tovar, JA; Xia, H | 2 |
| Diez-Pardo, JA; Losada, A; Migliazza, L; Santisteban, P; Tovar, JA; Xia, H | 1 |
| Archer, SL; Bourbon, JR; Dinh-Xuan, AT; Mercier, JC; Rambaud, C; Thébaud, B; Tibboel, D | 1 |
| Adzick, NS; Davies, P; Flake, AW; Kitano, Y; von Allmen, D | 1 |
| Connell, MG; Freese, R; Kluth, D; Laval, S; Lloyd, DA; Losty, PD; Okoye, BO; Smith, A | 1 |
| Miyazaki, E; Ohshiro, K; Oue, T; Puri, P; Shima, H; Taira, Y | 1 |
| Oue, T; Puri, P; Shima, H; Taira, Y | 1 |
| Connell, MG; Fernig, DG; Jesudason, EC; Lloyd, DA; Losty, PD | 3 |
| Deimling, J; Keijzer, R; Liu, J; Post, M; Tibboel, D | 1 |
| Allan, DW; Babiuk, RP; Greer, JJ; Lemke, RP | 1 |
| Battistini, B; Cloutier, R; Fournier, L; Jean, S; Jeng, AY; Kavanagh, M; Kluth, D; Major, D | 1 |
| Guarino, N; Puri, P; Shima, H | 3 |
| Miyazaki, E; Ohshiro, K; Puri, P; Shima, H; Taira, Y | 1 |
| Areias, JC; Baptista, MJ; Carvalho, JL; Correia-Pinto, J; Estêvão-Costa, J; Ferreira, A; Leite-Moreira, AF | 1 |
| Guarino, N; Oue, T; Puri, P; Shima, H | 2 |
| Gebb, SA; Guilbert, TW; Shannon, JM | 1 |
| Allan, DW; Babiuk, RP; Bagnall, K; Cote, D; Greer, JJ; Lemke, RP; Ly, L; Zhang, W | 1 |
| Adzick, NS; Davies, P; Flake, AW; Kanai, M; Kitano, Y; Radu, A; von Allmen, D; Yang, EY | 1 |
| Hashizume, K; Iwamori, M; Utsuki, T | 1 |
| Adzick, NS; Davies, P; Flake, AW; Kanai, M; Kitano, Y; von Allmen, D | 1 |
| Puri, P; Teramoto, H | 1 |
| Diez-Pardo, JA; Gonzalez, S; Rodriguez, JI; Tovar, JA; Yu, J | 1 |
| Areias, JC; Baptista, MJ; Carvalho, JL; Correia-Pinto, J; Leite-Moreira, A | 1 |
| Barlier-Mur, AM; Bourbon, JR; Chailley-Heu, B; Dinh-Xuan, AT; Henrion-Caude, A; Thébaud, B; Tibboel, D | 1 |
| Guarino, N; Puri, P; Teramoto, H | 1 |
| Feng, J; Hu, T; Hu, X; Jia, H; Jiang, X; Liu, W; Tang, Y | 1 |
| Bloechle, C; Huppertz, C; Izbicki, JR; Kluth, D; Lambrecht, W; Langwieler, TE; Mann, O; Tander, B | 1 |
| Oue, T; Puri, P; Shima, H; Taira, Y; Yoneda, A | 1 |
| Chinoy, MR; Graybill, MM; Kauffman, GL; Lang, CM; Miller, SA | 1 |
| Bos, AP; Bos, JA; Go, AT; Lachmann, B; Scheffers, EC; Silveri, F; Sluiter, W; Tenbrinck, R; Tibboel, D | 1 |
| Aldazabal, P; Alfonso, LF; Lopez de Torre, B; Tovar, JA; Uriarte, S; Vilanova, J | 1 |
| Bos, AP; Koster, JF; Kraakslee, R; Molenaar, JC; Silveri, F; Sluiter, W; Tenbrinck, R; Tibboel, D | 1 |
| Bos, AP; Gaillard, JL; Kluth, D; Lachmann, B; Molenaar, JC; Tenbrinck, R; Tibboel, D | 1 |
| Kangah, R; Kluth, D; Lambrecht, W; Reich, P; Tenbrinck, R; Tibboel, D | 1 |
| Kang, YJ; Manson, JM; Zolna, L | 1 |
| Ferrell, JM; Gray, LE; Kavlock, RJ; Ostby, JS | 1 |
2 review(s) available for nitrofen and Diaphragmatic Hernia
| Article | Year |
|---|---|
The embryology of the diaphragm.
Topics: Animals; Diaphragm; Disease Models, Animal; Hernia; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Liver; Lung; Mesoderm; Microscopy, Electron, Scanning; Peritoneum; Pesticides; Phenyl Ethers; Pleural Cavity; Rats | 2011 |
Recent advances in understanding the pathogenesis of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Muscle, Skeletal; Phenyl Ethers; Rats | 2000 |
193 other study(ies) available for nitrofen and Diaphragmatic Hernia
| Article | Year |
|---|---|
Decreased expression of GATA4 in the diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Down-Regulation; Female; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pleura; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2013 |
Disruption of the bone morphogenetic protein receptor 2 pathway in nitrofen-induced congenital diaphragmatic hernia.
Topics: Actins; Animals; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Lung; p38 Mitogen-Activated Protein Kinases; Phenyl Ethers; Phosphotyrosine; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad Proteins | 2013 |
Downregulated bone morphogenetic protein signaling in nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Bone Morphogenetic Proteins; Down-Regulation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Aberrant pulmonary lymphatic development in the nitrofen mouse model of congenital diaphragmatic hernia.
Topics: Animals; Biomarkers; Blotting, Western; Endothelial Cells; Female; Fluorescent Antibody Technique; Glycoproteins; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hyperplasia; Lung; Lymphoid Tissue; Membrane Transport Proteins; Mice; Phenyl Ethers; Platelet Endothelial Cell Adhesion Molecule-1; Pregnancy; Up-Regulation; Vascular Endothelial Growth Factor D; Vascular Endothelial Growth Factor Receptor-3 | 2013 |
Pulmonary FGF9 gene expression is downregulated during the pseudoglandular stage in nitrofen-induced hypoplastic lungs.
Topics: Animals; Down-Regulation; Female; Fibroblast Growth Factor 9; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2014 |
Spatiotemporal alterations in Sprouty-2 expression and tyrosine phosphorylation in nitrofen-induced pulmonary hypoplasia.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Nerve Tissue Proteins; Phenyl Ethers; Phosphotyrosine; Pregnancy; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; RNA, Messenger; Specific Pathogen-Free Organisms | 2013 |
Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Insulin-Like Growth Factor II; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Trophoblasts; Up-Regulation | 2014 |
Decreased apelin and apelin-receptor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Apelin; Apelin Receptors; Blotting, Western; Cell Survival; Disease Models, Animal; Female; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Intercellular Signaling Peptides and Proteins; Lung; Microscopy, Confocal; Phenyl Ethers; Pregnancy; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled; RNA, Messenger | 2014 |
NKCC-1 and ENaC are down-regulated in nitrofen-induced hypoplastic lungs with congenital diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Down-Regulation; Epithelial Sodium Channels; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2008 |
Maternal administration of betamethasone inhibits proliferation induced by fetal tracheal occlusion in the nitrofen rat model for congenital diaphragmatic hernia: a placebo-controlled study.
Topics: Animals; Betamethasone; Disease Models, Animal; Female; Fetal Organ Maturity; Fetal Weight; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Ligation; Lung; Lung Diseases; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Surgical Instruments; Teratogens; Trachea | 2008 |
Effect of prenatal tetrandrine administration on transforming growth factor-beta1 level in the lung of nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Abnormalities, Drug-Induced; Animals; Benzylisoquinolines; Down-Regulation; Drugs, Chinese Herbal; Female; Hernia, Diaphragmatic; Immunoenzyme Techniques; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2009 |
Expression of chloride channels in trachea-occluded hyperplastic lungs and nitrofen-induced hypoplastic lungs in rats.
Topics: Animals; Chloride Channels; CLC-2 Chloride Channels; Down-Regulation; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hyperplasia; Lung; Lung Diseases; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Trachea; Up-Regulation | 2009 |
Early development of the primordial mammalian diaphragm and cellular mechanisms of nitrofen-induced congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Diaphragm; Disease Models, Animal; Embryo, Mammalian; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Maternal Exposure; Mice; NIH 3T3 Cells; Peritoneum; Pesticides; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2010 |
Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Hernia, Diaphragmatic; Immunohistochemistry; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Upregulation of endothelin receptors A and B in the nitrofen induced hypoplastic lung occurs early in gestation.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Up-Regulation | 2010 |
Prenatal retinoic acid up-regulates pulmonary gene expression of COUP-TFII, FOG2, and GATA4 in pulmonary hypoplasia.
Topics: Animals; COUP Transcription Factor II; Disease Models, Animal; DNA-Binding Proteins; Female; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Humans; Lung; Mice; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors; Tretinoin; Up-Regulation | 2009 |
Microscopic magnetic resonance in congenital diaphragmatic hernia and associated malformations in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Microscopy; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2010 |
Disturbance of parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Lung Diseases; Parathyroid Hormone-Related Protein; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
Upregulation of Slit-2 and Slit-3 gene expressions in the nitrofen-induced hypoplastic lung.
Topics: Animals; Female; Fetal Organ Maturity; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Intercellular Signaling Peptides and Proteins; Lung; Membrane Proteins; Nerve Tissue Proteins; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Roundabout Proteins; Up-Regulation | 2009 |
Up-regulation of Wnt5a gene expression in the nitrofen-induced hypoplastic lung.
Topics: Actins; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Mice; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Up-Regulation; Wnt Proteins; Wnt-5a Protein | 2009 |
Is there a role for antioxidants in prevention of pulmonary hypoplasia in nitrofen-induced rat model of congenital diaphragmatic hernia?
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Drug Synergism; Female; Fetus; Free Radical Scavengers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipid Peroxidation; Lung; Lung Diseases; Male; Maternal-Fetal Exchange; Pesticides; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E | 2010 |
Bronchopulmonary innervation defects in infants and rats with congenital diaphragmatic hernia.
Topics: Animals; Bronchi; Disease Models, Animal; Female; Glial Cell Line-Derived Neurotrophic Factor; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Immunoblotting; Immunohistochemistry; Lung; Neural Crest; Neuroglia; Phenyl Ethers; Pregnancy; Proto-Oncogene Proteins c-ret; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Trachea; Ubiquitin Thiolesterase | 2010 |
Spatiotemporal alteration in phosphatidylinositide 3-kinase-serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Fetal Diseases; Fetal Organ Maturity; Functional Laterality; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Mice; Morphogenesis; Phenyl Ethers; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors | 2010 |
Expression and function of phosphodiesterases in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hyperoxia; Phenyl Ethers; Phosphoric Diester Hydrolases; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Vasodilation | 2010 |
The effect of in vitro tracheal occlusion on branching morphogenesis in fetal lung explants from the rat nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Bronchi; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; In Vitro Techniques; Lung; Morphogenesis; Phenyl Ethers; Rats; Trachea | 2010 |
Insulin receptor is downregulated in the nitrofen-induced hypoplastic lung.
Topics: Animals; Down-Regulation; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Receptor, Insulin | 2010 |
Antenatal steroid and tracheal occlusion restore vascular endothelial growth factor receptors in congenital diaphragmatic hernia rat model.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Sensitivity and Specificity; Steroids; Tracheal Stenosis | 2010 |
Prenatal retinoic acid upregulates pulmonary gene expression of PI3K and AKT in nitrofen-induced pulmonary hypoplasia.
Topics: Animals; Disease Models, Animal; Female; Fetal Diseases; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Morphogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tretinoin; Up-Regulation | 2010 |
Gene expression analysis in hypoplastic lungs in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Genome-Wide Association Study; Hernia, Diaphragmatic; Humans; Infant, Newborn; Lung; Oligonucleotide Array Sequence Analysis; Persistent Fetal Circulation Syndrome; Phenyl Ethers; Rats | 2010 |
Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Fetal Development; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Morphogenesis; Oxidative Stress; Phenyl Ethers; Platelet-Derived Growth Factor; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Downregulation of FGFRL1 contributes to the development of the diaphragmatic defect in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rats; Receptor, Fibroblast Growth Factor, Type 1 | 2011 |
Connective tissue growth factor expression pattern in lung development.
Topics: Abnormalities, Drug-Induced; Animals; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fetal Development; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Ligation; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trachea | 2010 |
Embryonic Wnt gene expression in the nitrofen-induced hypoplastic lung using 3-dimensional imaging.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Imaging, Three-Dimensional; In Situ Hybridization; Lung; Mice; Phenyl Ethers; Pregnancy; Pregnancy, Animal; RNA; Tomography, Optical; Wnt Proteins; Wnt2 Protein | 2010 |
Effect of insulin-like growth factors on lung development in a nitrofen-induced CDH rat model.
Topics: Actins; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Membrane Glycoproteins; Nuclear Proteins; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatomedins; Thyroid Nuclear Factor 1; Tissue Culture Techniques; Transcription Factors | 2011 |
Prenatal retinoic acid treatment upregulates late gestation lung protein 1 in the nitrofen-induced hypoplastic lung in late gestation.
Topics: Animals; Female; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin | 2011 |
Expression of the Wilm's tumor gene WT1 during diaphragmatic development in the nitrofen model for congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Genes, Wilms Tumor; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2011 |
[Effect of ambroxol on lung development of rat models with nitrofen-induced congenital diaphragmatic hernia].
Topics: Ambroxol; Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2010 |
Effects of estrogen on lung development in a rat model of diaphragmatic hernia.
Topics: Animals; Arterioles; Drug Evaluation, Preclinical; Estradiol; Female; Fetal Organ Maturity; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Subcutaneous; Lung; Phenyl Ethers; Pregnancy; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta1 | 2010 |
Expression of Iroquois genes is up-regulated during early lung development in the nitrofen-induced pulmonary hypoplasia.
Topics: Actins; Animals; Embryonic Development; Epithelial-Mesenchymal Transition; Female; Fetal Organ Maturity; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Homeodomain Proteins; Lung; Morphogenesis; Phenyl Ethers; Pregnancy; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2011 |
The role of primary myogenic regulatory factors in the developing diaphragmatic muscle in the nitrofen-induced diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Diaphragm; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; MyoD Protein; Myogenic Regulatory Factor 5; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2011 |
Prenatal administration of retinoic acid upregulates connective tissue growth factor in the nitrofen CDH model.
Topics: Animals; Connective Tissue Growth Factor; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2011 |
Prenatal administration of retinoic acid upregulates insulin-like growth factor receptors in the nitrofen-induced hypoplastic lung.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2011 |
Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
Topics: Animals; Body Weight; Brain; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Nitric Oxide; Phenyl Ethers; Phosphodiesterase 5 Inhibitors; Piperazines; Pregnancy; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones | 2011 |
Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?
Topics: Animals; Carbohydrate Conformation; Disease Models, Animal; Epigenomics; Epitopes; Female; Fibroblast Growth Factors; Heparitin Sulfate; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Mice; Molecular Sequence Data; Morphogenesis; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2011 |
COUP-TFII gene expression is upregulated in embryonic pleuroperitoneal folds in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; COUP Transcription Factor II; Diaphragm; Female; Gene Expression; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Phenyl Ethers; Pleura; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2012 |
Retinoic acid rescues deficient airway innervation and peristalsis of hypoplastic rat lung explants.
Topics: Actins; Animals; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Keratolytic Agents; Lung; Male; Organ Culture Techniques; Peristalsis; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Tretinoin; Ubiquitin Thiolesterase | 2012 |
Upregulation of fibroblast growth factor receptor 2 and 3 in the late stages of fetal lung development in the nitrofen rat model.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Organogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; RNA, Messenger; Up-Regulation | 2012 |
Nitrofen interferes with trophoblastic expression of retinol-binding protein and transthyretin during lung morphogenesis in the nitrofen-induced congenital diaphragmatic hernia model.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Morphogenesis; Phenyl Ethers; Prealbumin; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Retinol-Binding Proteins; RNA; Trophoblasts | 2012 |
A longer tracheal occlusion period results in increased lung growth in the nitrofen rat model.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Female; Fetal Diseases; Fetus; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Time Factors; Trachea | 2012 |
The pulmonary mesenchymal tissue layer is defective in an in vitro recombinant model of nitrofen-induced lung hypoplasia.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Mesoderm; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens | 2012 |
Defective pulmonary innervation and autonomic imbalance in congenital diaphragmatic hernia.
Topics: Animals; Biomarkers; Case-Control Studies; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant; Infant, Newborn; Lung; Mice; Parasympathetic Nervous System; Phenyl Ethers; Pregnancy; S100 Proteins; Sympathetic Nervous System; Vasoactive Intestinal Peptide; Vesicular Acetylcholine Transport Proteins | 2012 |
Prenatal retinoic acid upregulates connexin 43 (Cx43) gene expression in pulmonary hypoplasia in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Cell Differentiation; Connexin 43; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelial Cells; Female; Fetal Therapies; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Intraperitoneal; Lung; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; Up-Regulation | 2012 |
Antenatal imatinib treatment reduces pulmonary vascular remodeling in a rat model of congenital diaphragmatic hernia.
Topics: Airway Remodeling; Animals; Apoptosis; Benzamides; Caspase 3; Cell Proliferation; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imatinib Mesylate; Ki-67 Antigen; Lung; Phenyl Ethers; Piperazines; Platelet-Derived Growth Factor; Pregnancy; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; RNA, Messenger | 2012 |
ANG-1 TIE-2 and BMPR signalling defects are not seen in the nitrofen model of pulmonary hypertension and congenital diaphragmatic hernia.
Topics: Angiopoietin-1; Animals; Animals, Newborn; Bone Morphogenetic Protein Receptors; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenyl Ethers; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Signal Transduction; Smad1 Protein; Smad5 Protein; Smad8 Protein | 2012 |
Alterations of peroxisome proliferator-activated receptor γ and monocyte chemoattractant protein 1 gene expression in the nitrofen-induced hypoplastic lung.
Topics: Animals; Biomarkers; Chemokine CCL2; Disease Models, Animal; Down-Regulation; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; PPAR gamma; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2012 |
Prenatal retinoic acid improves lung vascularization and VEGF expression in CDH rat.
Topics: Analysis of Variance; Angiogenesis Inducing Agents; Animals; Arterioles; Biomarkers; Blotting, Western; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Treatment Outcome; Tretinoin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Pax3 gene expression is not altered during diaphragmatic development in nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Embryonic Development; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Microscopy, Fluorescence; Paired Box Transcription Factors; PAX3 Transcription Factor; Peritoneum; Phenyl Ethers; Pleura; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Increased trophoblastic apoptosis mediated by neutrophil gelatinase-associated lipocalin (NGAL) activation in the nitrofen model of congenital diaphragmatic hernia.
Topics: Acute-Phase Proteins; Animals; Apoptosis; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipocalin-2; Lipocalins; Phenyl Ethers; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Trophoblasts | 2013 |
Decreased pulmonary c-Cbl expression and tyrosine phosphorylation in the nitrofen-induced rat model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Phosphorylation; Proto-Oncogene Proteins c-cbl; Rats; Rats, Sprague-Dawley; Tyrosine | 2013 |
Amniotic lamellar body count and congenital diaphragmatic hernia in humans and in a rat model.
Topics: Abnormalities, Multiple; Amniotic Fluid; Animals; Blotting, Western; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Lung; Lung Diseases; Magnetic Resonance Imaging; Microscopy, Electron, Transmission; Phenyl Ethers; Rats; Secretory Vesicles; Species Specificity; Statistics, Nonparametric | 2013 |
Effect of nitrofen in the final stages of development of the diaphragm muscle in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Myosins; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2013 |
Murine nitrofen-induced pulmonary hypoplasia does not involve induction of TGF-beta signaling.
Topics: Animals; DNA-Binding Proteins; Gene Expression; Hernia, Diaphragmatic; Lung; Mice; Organ Culture Techniques; Phenyl Ethers; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad4 Protein; Smad7 Protein; Trans-Activators; Transforming Growth Factor beta | 2002 |
Effect of mechanical ventilation on the pulmonary expression and production of elastin in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Culture Techniques; Elastin; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Hernia, Diaphragmatic; Humans; Infant, Newborn; Lung; Lung Compliance; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Reverse Transcriptase Polymerase Chain Reaction; Tropoelastin | 2002 |
Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse.
Topics: Animals; Biomarkers; Disease Models, Animal; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Mice; Organ Culture Techniques; Phenyl Ethers; RNA, Messenger | 2002 |
Challenging embryological theories on congenital diaphragmatic hernia: future therapeutic implications for paediatric surgery.
Topics: Animals; Cells, Cultured; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Models, Biological; Morphogenesis; Phenyl Ethers; Photomicrography; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Teratogens | 2002 |
Antenatal dexamethasone enhances endothelin-1 synthesis and gene expression in the heart in congenital diaphragmatic hernia in rats.
Topics: Animals; Base Sequence; Dexamethasone; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Glucocorticoids; Hernia, Diaphragmatic; Myocardial Contraction; Myocardium; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical | 2002 |
Embryological origins and development of the rat diaphragm.
Topics: Animals; Cell Division; Cell Movement; Diaphragm; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Mice; Muscle Development; Muscle Fibers, Skeletal; Phenyl Ethers; Phrenic Nerve; Proto-Oncogene Proteins c-met; Rats; Respiratory System Abnormalities; Stem Cells | 2003 |
Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Airway Obstruction; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Isoenzymes; Membrane Proteins; Muscle, Smooth; Pesticides; Phenyl Ethers; Potassium Chloride; Pregnancy; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
The activation of the retinoic acid response element is inhibited in an animal model of congenital diaphragmatic hernia.
Topics: Animals; beta-Galactosidase; Disease Models, Animal; Drug Interactions; Gene Expression; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; In Vitro Techniques; Lac Operon; Mice; Phenyl Ethers; Response Elements; Teratogens; Tretinoin | 2003 |
The adrenal cortex in experimental congenital diaphragmatic hernia.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; DNA; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2003 |
Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1: expression in the lung of fetal rats with nitrofen-induced diaphragmatic hernia.
Topics: Animals; Female; Fetus; Hernia, Diaphragmatic; Lung; Matrix Metalloproteinase 9; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Tissue Inhibitor of Metalloproteinases | 2003 |
Expression and activity of matrix metallo proteinases 2 and 9 and their inhibitors in rat lungs during the perinatal period and in diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; DNA Primers; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Organogenesis; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2003 |
Increased expression of ICAM-1 and VCAM-1 in the lung of nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Female; Fetus; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Intercellular Adhesion Molecule-1; Lung; Models, Animal; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiratory System Abnormalities; Vascular Cell Adhesion Molecule-1 | 2003 |
Gene expression of fibroblast growth factors 10 and 7 is downregulated in the lung of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Down-Regulation; Fetal Diseases; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Models, Animal; Phenyl Ethers; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Prenatal vitamin E improves lung and heart hypoplasia in experimental diaphragmatic [correction of diaphragamatic] hernia.
Topics: Animals; Antioxidants; Cell Line, Tumor; Female; Fetal Organ Maturity; Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Humans; Lung; Models, Animal; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiratory System Abnormalities; Vitamin E | 2003 |
Pulmonary surfactant protein A, B, and C mRNA and protein expression in the nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Disease Models, Animal; Embryo, Mammalian; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; In Situ Hybridization; Infant, Newborn; Lung; Phenyl Ethers; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Rats; Rats, Wistar; RNA, Messenger | 2003 |
Fetal heart development in the nitrofen-induced CDH rat model: the role of mechanical and nonmechanical factors.
Topics: Animals; Female; Fetal Heart; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Myocardium; Organ Size; Phenyl Ethers; Rats; Rats, Wistar | 2003 |
Nitrofen-induced congenital diaphragmatic hernia in rat embryo: what model?
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Liver; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Effect of epidermal growth factor on pulmonary hypoplasia in experimental diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Epidermal Growth Factor; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Electron; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2004 |
Reductions in the incidence of nitrofen-induced diaphragmatic hernia by vitamin A and retinoic acid.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Hernia, Diaphragmatic; Incidence; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Tretinoin; Vitamin A | 2004 |
The vagus and recurrent laryngeal nerves in experimental congenital diaphragmatic hernia.
Topics: Animals; Female; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imaging, Three-Dimensional; Models, Animal; Neural Crest; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Recurrent Laryngeal Nerve; Vagus Nerve | 2004 |
Pulmonary elastin expression is decreased in the nitrofen-induced rat model of congenital diaphragmatic hernia.
Topics: Animals; Desmosine; Disease Models, Animal; Elastin; Female; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Diaphragm; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation, Developmental; Genes, Reporter; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Heterozygote; Lac Operon; Mice; Mice, Transgenic; Morphogenesis; Phenyl Ethers; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein B; Vascular Endothelial Growth Factor A | 2004 |
The relationship of diaphragmatic defect, liver growth, and lung hypoplasia in nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Body Weight; Diaphragm; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Image Processing, Computer-Assisted; Liver; Lung; Microscopy, Electron, Scanning; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Thorax; Video Recording | 2004 |
Altered expression of angiotensin II receptor subtypes and transforming growth factor-beta in the heart of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Heart; Herbicides; Hernia, Diaphragmatic; Maternal Exposure; Myocardium; Phenyl Ethers; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Transforming Growth Factor beta | 2005 |
Can maternal vitamin e supplementation prevent lung hypoplasia in the nitrofen-induced rat model of congenital diaphragmatic hernia?
Topics: Animals; Antioxidants; Dietary Supplements; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Lung Diseases; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Vitamin E | 2005 |
Pax3 mRNA is decreased in the hearts of rats with experimental diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; DNA-Binding Proteins; Female; Gene Expression Regulation, Developmental; Heart; Herbicides; Hernia, Diaphragmatic; Maternal Exposure; Myocardium; Paired Box Transcription Factors; PAX3 Transcription Factor; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2005 |
Differential effects of vitamin A on fetal lung growth and diaphragmatic formation in nitrofen-induced rat model.
Topics: Animals; Female; Fetal Development; Herbicides; Hernia, Diaphragmatic; In Situ Hybridization; Lung; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Vitamin A | 2005 |
Expression of vasoactive mediators during mechanical ventilation in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelin-1; Female; Gene Expression Regulation, Developmental; Herbicides; Hernia, Diaphragmatic; Lung; Maternal Exposure; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Circulation; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Resistance; Vasoconstriction; Vasodilation | 2005 |
Congenital diaphragmatic hernia, tracheal occlusion, thyroid transcription factor-1, and fetal pulmonary epithelial maturation.
Topics: Airway Obstruction; Animals; Animals, Newborn; Epithelial Cells; Female; Fetal Organ Maturity; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Lung; Male; Nuclear Proteins; Pesticides; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Pulmonary Surfactant-Associated Protein C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Nuclear Factor 1; Trachea; Transcription Factors | 2005 |
Insulinlike growth factor I gene expression is increased in the fetal lung after tracheal ligation.
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fetal Proteins; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hyperplasia; Insulin-Like Growth Factor I; Ligation; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Somatotropin; RNA, Messenger; Thioredoxins; Trachea | 2005 |
Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Olive Oil; Phenyl Ethers; Plant Oils; Pregnancy; Rats; Rats, Wistar; Vitamin A; Vitamins | 2005 |
Effects of prenatal vitamins A, E, and C on the hypoplastic hearts of fetal rats with diaphragmatic hernia.
Topics: Animals; Apoptosis; Ascorbic Acid; Disease Models, Animal; DNA; Female; Fetal Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; In Situ Nick-End Labeling; Oxidants; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Vitamin A; Vitamin E; Vitamins | 2005 |
Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses.
Topics: Absorption; Amiloride; Animals; Animals, Newborn; Body Fluids; Epinephrine; Epithelial Sodium Channels; Female; Fetal Organ Maturity; Fetus; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Male; Phenyl Ethers; Pregnancy; Propranolol; Rats; Rats, Sprague-Dawley; Respiratory System Abnormalities; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 2006 |
Nitrovasodilator responses in pulmonary arterioles from rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Atrial Natriuretic Factor; Cyclic GMP; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Nitric Oxide; Nitroprusside; Pesticides; Phenyl Ethers; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2005 |
Expression of Connexin 43 in the hearts of rat embryos exposed to nitrofen and effects of vitamin A on it.
Topics: Abnormalities, Multiple; Analysis of Variance; Animals; Connexin 43; Disease Models, Animal; Female; Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Neural Crest; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Vitamin A | 2006 |
Altered renin-angiotensin system gene expression causes renal hypoplasia in the rats with nitrofen-induced diaphragmatic hernia.
Topics: Abnormalities, Multiple; Animals; Down-Regulation; Female; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Kidney; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2006 |
Sex and congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Disorders of Sex Development; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Male; Maternal Exposure; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Differentiation | 2006 |
[Aplication of a 3D reconstruction model for the analysis of nitrofen induced intrathoracic malformations].
Topics: Animals; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imaging, Three-Dimensional; Phenyl Ethers; Radiography; Rats; Rats, Sprague-Dawley | 2005 |
Improvement of pulmonary hypoplasia associated with congenital diaphragmatic hernia by in utero CFTR gene therapy.
Topics: Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Fetal Diseases; Genetic Therapy; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2006 |
Vitamin A improves Pax3 expression that is decreased in the heart of rats with experimental diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Hernia, Diaphragmatic; Myocardium; Paired Box Transcription Factors; PAX3 Transcription Factor; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Vitamin A | 2006 |
Ghrelin expression in human and rat fetal lungs and the effect of ghrelin administration in nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Fetus; Gestational Age; Ghrelin; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; In Situ Hybridization; Lung; Peptide Hormones; Phenyl Ethers; Rats; Receptors, G-Protein-Coupled; Receptors, Ghrelin | 2006 |
Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists; Female; Fluorescent Dyes; Gap Junctions; Gestational Age; Hernia, Diaphragmatic; Humans; Lung; Lung Compliance; Morphogenesis; Muscle, Smooth; Phenyl Ethers; Potassium Chloride; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Respiratory System Abnormalities; Sarcoplasmic Reticulum; Tissue Culture Techniques | 2006 |
[Thyroid C cells are decreased in experimental CDH].
Topics: Animals; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Male; Neural Crest; Pesticides; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Research Design; Thyroid Diseases; Thyroid Gland | 2006 |
Effects of antioxidant vitamins on molecular regulators involved in lung hypoplasia induced by nitrofen.
Topics: Animals; Antioxidants; Ascorbic Acid; Female; Hepatocyte Nuclear Factor 3-beta; Herbicides; Hernia, Diaphragmatic; Lung; Lung Diseases; Nuclear Proteins; Organ Size; Peptide Fragments; Phenyl Ethers; Pregnancy; Proteolipids; Rats; Rats, Sprague-Dawley; Respiratory System Abnormalities; Thyroid Nuclear Factor 1; Transcription Factors; Up-Regulation; Vitamin A; Vitamin E; Vitamins | 2006 |
Myocardium expression of connexin 43, SERCA2a, and myosin heavy chain isoforms are preserved in nitrofen-induced congenital diaphragmatic hernia rat model.
Topics: Animals; Calcium-Transporting ATPases; Connexin 43; Disease Models, Animal; Female; Fetal Organ Maturity; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Myocardium; Myosin Heavy Chains; Pesticides; Phenyl Ethers; Pregnancy; Protein Isoforms; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2006 |
Spatial and temporal expression of glucocorticoid, retinoid, and thyroid hormone receptors is not altered in lungs of congenital diaphragmatic hernia.
Topics: Animals; Gene Expression Regulation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Phenyl Ethers; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoid X Receptors; RNA, Messenger | 2006 |
Altered regulation of retinoic acid synthesis in nitrofen-induced hypoplastic lung.
Topics: Acyltransferases; Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Developmental; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Olive Oil; Phenyl Ethers; Plant Oils; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Retinal Dehydrogenase; Retinoic Acid 4-Hydroxylase; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2007 |
Kidney development in the nitrofen-induced pulmonary hypoplasia and congenital diaphragmatic hernia in rats.
Topics: Animals; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Kidney; Kidney Diseases; Lung; Lung Diseases; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Retinoids; Toxins, Biological | 2007 |
Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Animals; Biomarkers; Cell Differentiation; Epithelial Cells; Female; Gene Expression; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Disturbance of retinol transportation causes nitrofen-induced hypoplastic lung.
Topics: Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Hernia, Diaphragmatic; Lung; Lung Diseases; Morphogenesis; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Signal Transduction; Vitamin A | 2007 |
Reduced expression of aquaporin 5 water channel in nitrofen-induced hypoplastic lung with congenital diaphragmatic hernia rat model.
Topics: Animals; Animals, Newborn; Aquaporin 5; Disease Models, Animal; Down-Regulation; Female; Fetus; Gene Expression Regulation; Genetic Markers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Male; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Statistics, Nonparametric | 2007 |
Down-regulation of Wnt signal pathway in nitrofen-induced hypoplastic lung.
Topics: Animals; Disease Models, Animal; Down-Regulation; Embryo, Nonmammalian; Female; GATA6 Transcription Factor; Gene Expression Regulation, Developmental; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Signal Transduction | 2007 |
Vitamin A deficiency (VAD), teratogenic, and surgical models of congenital diaphragmatic hernia (CDH).
Topics: Animals; Diaphragm; Disease Models, Animal; Dogs; Hernia, Diaphragmatic; Lung; Models, Animal; Phenyl Ethers; Rabbits; Rats; Sheep; Signal Transduction; Species Specificity; Teratogens; Tretinoin; Vitamin A; Vitamin A Deficiency | 2007 |
[Effect of tetrandrine on endothelin expression in the lungs and clinical significance thereof: experiment with rat models with nitrofen-induced congenital diaphragmatic hernia].
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Disease Models, Animal; Endothelins; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2007 |
Embryonic essential myosin light chain regulates fetal lung development in rats.
Topics: Abnormalities, Drug-Induced; Animals; Cardiac Myosins; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Muscle, Smooth; Myosin Light Chains; Phenyl Ethers; Pregnancy; Proteomics; Rats; Rats, Sprague-Dawley; Tissue Culture Techniques; Vitamin A | 2007 |
Pulmonary epithelial cell differentiation in the nitrofen-induced congenital diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Epithelial Cells; Female; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Homeodomain Proteins; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor HES-1; Uteroglobin | 2007 |
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Drug Interactions; Embryonic Structures; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Mice; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Retinoids; Signal Transduction; Teratogens; Thyroid Hormones; Vitamin A; Vitamin E | 2007 |
Effect of antenatal tetrandrine administration on endothelin-1 and epidermal growth factor levels in the lungs of rats with experimental diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Benzylisoquinolines; Birth Weight; Dexamethasone; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelin-1; Epidermal Growth Factor; Female; Fetal Organ Maturity; Hernia, Diaphragmatic; Lung; Organ Size; Phenyl Ethers; Pregnancy; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
The effect of tracheal occlusion on lung branching in the rat nitrofen CDH model.
Topics: Animals; Body Weight; Bronchi; Cell Proliferation; Disease Models, Animal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Size; Pesticides; Phenyl Ethers; Pregnancy; Rats; Trachea | 2008 |
[Effect of tetrandrine on lung development: experiment of nitrofen-induced congenital diaphragmatic hernia fetal rat model].
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Electron; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Down-Regulation; Female; GATA4 Transcription Factor; GATA6 Transcription Factor; Gene Expression Regulation, Developmental; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity | 2008 |
Prenatal treatment with retinoic acid accelerates type 1 alveolar cell proliferation of the hypoplastic lung in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Drug Administration Schedule; Epithelial Cells; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Pregnancy; Pregnancy, Animal; Prenatal Care; Probability; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiratory System Abnormalities; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Tretinoin | 2008 |
Perinatal profile of ventricular overload markers in congenital diaphragmatic hernia.
Topics: Adaptation, Biological; Angiotensinogen; Animals; Base Sequence; Biomarkers; Endothelin-1; Gene Expression; Genetic Markers; Heart Ventricles; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Molecular Sequence Data; Myocardium; Natriuretic Peptide, Brain; Phenyl Ethers; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
Intrinsic catch-up growth of hypoplastic fetal lungs is mediated by interleukin-6.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Interleukin-6; Lung; Lung Diseases; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Antenatal glucocorticoid corrects pulmonary immaturity in experimentally induced congenital diaphragmatic hernia in rats.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Dexamethasone; Female; Fetal Organ Maturity; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Maternal-Fetal Exchange; Nitric Oxide Synthase; Phenyl Ethers; Phosphatidylcholines; Pregnancy; Proteolipids; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Embryonic cell death patterns associated with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Cell Death; Diaphragm; Ganglia, Sympathetic; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Mesoderm; Phagosomes; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Staining and Labeling; Time Factors | 1995 |
Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia.
Topics: Amino Acid Sequence; Animals; Base Sequence; Endothelium; Female; Gene Expression; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunoblotting; Lung; Molecular Sequence Data; Nitric Oxide Synthase; Phenyl Ethers; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Prenatal hormonal therapy improves pulmonary compliance in the nitrofen-induced CDH rat model.
Topics: Animals; Dexamethasone; Drug Therapy, Combination; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Lung Compliance; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome, Newborn; Respiratory Mechanics; Thyrotropin-Releasing Hormone | 1995 |
Nitrofen-induced diaphragmatic hernias in rats: an animal model.
Topics: Animals; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Rabbits; Rats | 1993 |
Lung growth and maturation in the rat model of experimentally induced congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Pulmonary Surfactants; Rats; Rats, Wistar | 1993 |
Prenatal hormonal therapy improves pulmonary compliance in the nitrofen-induced CDH rat model.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Disease Models, Animal; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Prenatal Care; Rats | 1996 |
Intestinal rotation in experimental congenital diaphragmatic hernia.
Topics: Abnormalities, Drug-Induced; Animals; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Intestines; Lung; Phenyl Ethers; Rats; Torsion Abnormality | 1995 |
Decreased pulmonary nitric oxide synthase activity in the rat model of congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 1996 |
Embryology of congenital diaphragmatic hernia.
Topics: Animals; Cell Differentiation; Diaphragm; Disease Models, Animal; Epithelial Cells; Epithelium; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Rats | 1996 |
Nitrofen dose-dependent gestational day-specific murine lung hypoplasia and left-sided diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fetus; Gestational Age; Hernia, Diaphragmatic; Lung; Mice; Mice, Inbred Strains; Microscopy, Electron; Phenyl Ethers | 1997 |
Prenatal hormones alter antioxidant enzymes and lung histology in rats with congenital diaphragmatic hernia.
Topics: Animals; Birth Weight; Dexamethasone; DNA; Drug Synergism; Female; Glutathione Peroxidase; Glutathione Reductase; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lung Compliance; Pesticides; Phenyl Ethers; Pneumothorax; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thyrotropin-Releasing Hormone | 1997 |
Pathogenesis of nitrofen-induced congenital diaphragmatic hernia in fetal rats.
Topics: Animals; Diaphragm; Embryonic and Fetal Development; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Phrenic Nerve; Rats; Rats, Sprague-Dawley | 1997 |
Effect of prenatal glucocorticoids on pulmonary vascular muscularisation in nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Dexamethasone; Female; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Muscle, Smooth, Vascular; Persistent Fetal Circulation Syndrome; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1998 |
Pulmonary vascular balance in congenital diaphragmatic hernia: enhanced endothelin-1 gene expression as a possible cause of pulmonary vasoconstriction.
Topics: Animals; Blotting, Northern; Endothelin-1; Female; Gene Expression; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Persistent Fetal Circulation Syndrome; Phenyl Ethers; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger; Up-Regulation; Vasoconstriction | 1998 |
Antenatal glucocorticoid therapy suppresses angiotensin-converting enzyme activity in rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Dexamethasone; Female; Fetal Diseases; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Peptidyl-Dipeptidase A; Persistent Fetal Circulation Syndrome; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 1998 |
Inhibition of vascular and epithelial differentiation in murine nitrofen-induced diaphragmatic hernia.
Topics: Actins; Animals; Blood Vessels; Capillaries; Embryonic and Fetal Development; Epithelium; Hernia, Diaphragmatic; Lung; Mice; Mice, Inbred ICR; Muscle, Smooth; Muscle, Smooth, Vascular; Nuclear Proteins; Phenyl Ethers; Pulmonary Surfactants; RNA, Messenger; Thyroid Nuclear Factor 1; Transcription Factors | 1998 |
Administration of antenatal glucocorticoids prevents pulmonary artery structural changes in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Female; Fetal Diseases; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Image Processing, Computer-Assisted; Immunohistochemistry; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 1998 |
Effect of dexamethasone on endothelial nitric oxide synthase in experimental congenital diaphragmatic hernia.
Topics: Animals; Blotting, Western; Dexamethasone; Endothelium, Vascular; Female; Fetal Diseases; Glucocorticoids; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Nitric Oxide Synthase; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 1998 |
Hypoxic pulmonary vasoconstriction is impaired in rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Arterioles; Disease Models, Animal; Female; Fetus; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypoxia; Phenyl Ethers; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Pulmonary arterioles from rats with congenital diaphragmatic hernias are hypoplastic but not hyperresponsive.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Phenylephrine; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Differential gene expression at gestational days 14 and 16 in normal and nitrogen-induced hypoplastic murine fetal lungs with coexistent diaphragmatic hernia.
Topics: Animals; DNA, Complementary; Female; Fetal Organ Maturity; Gene Expression Regulation, Developmental; Genetic Techniques; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Mice; Pesticides; Phenyl Ethers; Pregnancy; RNA | 1998 |
Heart hypoplasia in experimental congenital diaphragmatic hernia.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Female; Heart; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Myocardium; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens | 1999 |
Increased tropoelastin and procollagen expression in the lung of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Teratogens; Tropoelastin | 1999 |
Effect of antenatal glucocorticoid administration on insulin-like growth factor I and II levels in hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Female; Fetal Organ Maturity; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Pulmonary neuroendocrine cells in nitrofen-induced diaphragmatic hernia and the effect of prenatal glucocorticoids.
Topics: Animals; Calcitonin Gene-Related Peptide; Dexamethasone; Female; Fetal Organ Maturity; Glucocorticoids; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Neurosecretory Systems; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
The tracheobronchial tree is abnormal in experimental congenital diaphragmatic hernia.
Topics: Animals; Bronchi; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Trachea; Tracheal Stenosis | 1999 |
Lung hypoplasia caused by nitrofen is mediated by down-regulation of thyroid transcription factor TTF-1.
Topics: Animals; Down-Regulation; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Homeodomain Proteins; Humans; Lung; Nuclear Proteins; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Nuclear Factor 1; Transcription Factors; Tumor Cells, Cultured | 1999 |
Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Body Weight; DNA; Female; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Incidence; Lung; Organ Size; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Proteins; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A | 1999 |
Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia.
Topics: Animals; Body Weight; Disease Models, Animal; DNA; Female; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Histocytochemistry; Lung; Organ Size; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Trachea; Tracheal Stenosis | 1999 |
Cardiovascular malformations in experimental congenital diaphragmatic hernia.
Topics: Animals; Female; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Antenatal dexamethasone suppresses tumor necrosis factor-alpha expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats.
Topics: Abnormalities, Drug-Induced; Animals; Dexamethasone; Female; Fetal Diseases; Gene Expression Regulation, Neoplastic; Glucocorticoids; Hernia, Diaphragmatic; In Situ Hybridization; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1999 |
Skeletal malformations associated with congenital diaphragmatic hernia: experimental and human studies.
Topics: Animals; Bone and Bones; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Phenyl Ethers; Pregnancy; Radiography; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Retrospective Studies; Ribs; Spine | 1999 |
Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Fibroblast Growth Factor 2; Gene Expression; Glucocorticoids; Growth Substances; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation | 2000 |
Early lung malformations in congenital diaphragmatic hernia.
Topics: Animals; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Culture Techniques; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2000 |
Cell proliferation and apoptosis in experimental lung hypoplasia.
Topics: Animals; Apoptosis; Bromodeoxyuridine; Cell Division; DNA; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2000 |
Antenatal dexamethasone enhances endothelin receptorB expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Endothelin-1; Female; Glucocorticoids; Herbicides; Hernia, Diaphragmatic; Hypertension, Pulmonary; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Division; Embryonic and Fetal Development; Epithelial Cells; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Models, Biological; Phenyl Ethers; Rats; Rats, Wistar | 2000 |
Effect of CGS 26303, an endothelin-converting enzyme-neutral endopeptidase inhibitor, on nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Body Weight; Disease Models, Animal; Endothelin-Converting Enzymes; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Subcutaneous; Linear Models; Liver; Lung; Metalloendopeptidases; Organ Size; Organophosphonates; Phenyl Ethers; Pregnancy; Proportional Hazards Models; Protease Inhibitors; Rats; Reference Values; Survival Analysis; Tetrazoles | 2000 |
In vitro effects of growth factors on lung hypoplasia in a model of congenital diaphragmatic hernia.
Topics: Animals; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Heparin; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Culture Techniques; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2000 |
Antenatal dexamethasone improves atrial natriuretic peptide receptors in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Animals, Newborn; Dexamethasone; Female; Glucocorticoids; Herbicides; Hernia, Diaphragmatic; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
Antenatal dexamethasone administration inhibits smooth-muscle-cell DNA synthesis in pulmonary-arterial media in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bromodeoxyuridine; Dexamethasone; Disease Models, Animal; DNA; Drug Evaluation, Preclinical; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Immunohistochemistry; Phenyl Ethers; Pregnancy; Prenatal Care; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tunica Media | 2000 |
Heart-related indices in experimental diaphragmatic hernia.
Topics: Animals; Female; Heart Ventricles; Hernia, Diaphragmatic; Hypoplastic Left Heart Syndrome; Models, Animal; Myocardium; Phenyl Ethers; Pregnancy; Rats; Rats, Wistar; Ventricular Dysfunction, Left | 2000 |
Antenatal dexamethasone enhances surfactant protein synthesis in the hypoplastic lung of nitrofen-induced diaphragmatic hernia in rats.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Female; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Phenyl Ethers; Pregnancy; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Protein A | 2000 |
Effect of hyperoxia on surfactant protein gene expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats.
Topics: Abnormalities, Drug-Induced; Animals; Female; Gene Expression Regulation; Glycoproteins; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hyperoxia; Lung; Male; Pesticides; Phenyl Ethers; Pregnancy; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development.
Topics: Animals; Cell Division; Disease Models, Animal; Endothelial Growth Factors; Extracellular Matrix Proteins; Female; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Lymphokines; Microscopy, Electron; Peptides; Pesticides; Phenyl Ethers; Pregnancy; Protein Precursors; Proteolipids; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2000 |
Structure of the primordial diaphragm and defects associated with nitrofen-induced CDH.
Topics: Animals; Diaphragm; Embryo, Mammalian; Embryonic and Fetal Development; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Image Processing, Computer-Assisted; Lung; Peritoneum; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2000 |
Antenatal dexamethasone administration increases fetal lung DNA synthesis and RNA and protein content in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Animals; Bromodeoxyuridine; Dexamethasone; DNA Replication; Female; Fetal Organ Maturity; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Phenyl Ethers; Pregnancy; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA; Stimulation, Chemical | 2000 |
BAPS prize-1999: Lung growth induced by prenatal tracheal occlusion and its modifying factors: a study in the rat model of congenital diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Lung; Maternal-Fetal Exchange; Organ Size; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Terbutaline; Tocolytic Agents; Trachea | 2001 |
Impaired spreading of surfactant phospholipids in the lungs of newborn rats with pulmonary hypoplasia as a model of congenital diaphragmatic hernia induced by nitrofen.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Blotting, Western; Body Weight; Chromatography, Thin Layer; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Organ Size; Phenyl Ethers; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Sphingomyelins | 2001 |
Structural immaturity of the heart in congenital diaphragmatic hernia in rats.
Topics: Abnormalities, Multiple; Actins; Animals; Disease Models, Animal; Elastin; Enzyme-Linked Immunosorbent Assay; Fetal Organ Maturity; Heart; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Procollagen; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tropoelastin | 2001 |
Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia: tracheal occlusion reverses the arterial structural abnormality.
Topics: Analysis of Variance; Animals; Female; Fetal Diseases; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Histocytochemistry; Lung; Phenyl Ethers; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Trachea | 2001 |
Gene expression of insulin-like growth factor-1 and epidermal growth factor is downregulated in the heart of rats with nitrofen-induced diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Down-Regulation; Epidermal Growth Factor; Female; Fetal Diseases; Gene Expression; Heart; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Insulin-Like Growth Factor I; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Neural crest-derived defects in experimental congenital diaphragmatic hernia.
Topics: Animals; Diaphragm; Disease Models, Animal; Female; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Neural Crest; Parathyroid Glands; Pesticides; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Thymus Gland; Thyroid Gland | 2001 |
[Prognostic indexes derived from ventricular morphology in congenital diaphragmatic hernia induced by nitrofen].
Topics: Animals; Heart Ventricles; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Prognosis; Rats; Rats, Wistar | 2001 |
Restoring effects of vitamin A on surfactant synthesis in nitrofen-induced congenital diaphragmatic hernia in rats.
Topics: Analysis of Variance; Animals; Blotting, Northern; Chromatography, Thin Layer; Disease Models, Animal; DNA; Female; Fetus; Fluorescent Antibody Technique; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Phenyl Ethers; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats; Rats, Wistar; RNA, Messenger; Vitamin A | 2001 |
Altered gene level expression of thyroid hormone receptors alpha-1 and beta-1 in the lung of nitrofen-induced diaphragmatic hernia.
Topics: Animals; DNA-Binding Proteins; Female; Gene Expression; Herbicides; Hernia, Diaphragmatic; Lung; Morphogenesis; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Thyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Effect of prenatal tetrandrine therapy on pulmonary vascular structural remodeling in the nitrofen-induced CDH rat model.
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2000 |
Effect of prenatal glucocorticoids and postnatal nitric oxide inhalation on survival of newborn rats with nitrofen-induced congenital diaphragmatic hernia.
Topics: Administration, Inhalation; Animals; Dexamethasone; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Intraperitoneal; Lung Compliance; Male; Nitric Oxide; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Survival Rate | 2002 |
Increased vascular endothelial growth factor peptide and gene expression in hypoplastic lung in nitrofen induced congenital diaphragmatic hernia in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Dexamethasone; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Lymphokines; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Angiopoietin-1 and VEGF in vascular development and angiogenesis in hypoplastic lungs.
Topics: Angiopoietin-1; Animals; Carbon; Coloring Agents; Endothelial Growth Factors; Enzyme Activation; Female; Hernia, Diaphragmatic; Immunohistochemistry; Lung; Lymphokines; MAP Kinase Signaling System; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Pesticides; Phenyl Ethers; Pregnancy; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Effect of artificial ventilation on pulmonary antioxidant enzyme activities in a congenital diaphragmatic hernia rat model.
Topics: Analysis of Variance; Animals; Catalase; Female; Fetus; Glutathione Peroxidase; Herbicides; Hernia, Diaphragmatic; Isoenzymes; Lung; Maternal-Fetal Exchange; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Superoxide Dismutase | 1992 |
The kidney in the fetal rat model of congenital diaphragmatic hernia induced by nitrofen.
Topics: Abnormalities, Drug-Induced; Animals; Diaphragm; Disease Models, Animal; Female; Herbicides; Hernia, Diaphragmatic; Kidney; Lung; Phenyl Ethers; Pregnancy; Rats | 1992 |
Nitrofen-induced diaphragmatic hernias in rats: pulmonary antioxidant enzyme activities.
Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Disease Models, Animal; Female; Glutathione Peroxidase; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Maternal-Fetal Exchange; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Superoxide Dismutase | 1992 |
Experimentally induced congenital diaphragmatic hernia in rats.
Topics: Animals; Body Weight; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Organ Size; Phenyl Ethers; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Respiratory Insufficiency | 1990 |
Nitrofen-induced diaphragmatic hernias in rats: an animal model.
Topics: Animals; Disease Models, Animal; Female; Gestational Age; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Incidence; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Inbred Strains; Regression Analysis | 1990 |
Strain differences in response of Sprague-Dawley and Long Evans Hooded rats to the teratogen nitrofen.
Topics: Abnormalities, Drug-Induced; Animals; Female; Heart Defects, Congenital; Hernia, Diaphragmatic; Hydronephrosis; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
The postnatal effects of prenatal exposure to low doses of nitrofen (2,4-dichlorophenyl-p-nitrophenyl ether) in Sprague-Dawley rats.
Topics: Animals; Autopsy; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Herbicides; Hernia, Diaphragmatic; Male; Maternal-Fetal Exchange; Mice; Motor Activity; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reproduction; Teratogens | 1985 |