nitrites has been researched along with Subarachnoid Hemorrhage in 21 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)." | 7.70 | Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000) |
| " This study tested the hypothesis that enhancement of S-nitrosylated hemoglobin by ethyl nitrite inhalation improves outcome after experimental subarachnoid hemorrhage (SAH)." | 3.77 | Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. ( Auten, RL; Demchenko, IT; Piantadosi, CA; Reynolds, JD; Sheng, H; Stamler, JS; Warner, DS, 2011) |
| "Subacute sodium nitrite infusions prevented delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage." | 3.73 | Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. ( Dejam, A; Gladwin, MT; Grimes, G; Oldfield, EH; Pluta, RM, 2005) |
| "To test whether migraine and subarachnoid hemorrhage (SAH) are associated with increased sympathetic tone, we compared the neuropeptide Y-like (NPY-LI) and chromogranin A-like immunoreactivities (LI) of cerebrospinal fluid (CSF) from migraneurs and SAH patients with those from control subjects." | 3.70 | Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF. ( Donoso, MV; Huidobro-Toro, JP; Mellado, PA; Valenzuela, RF, 2000) |
| "Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)." | 3.70 | Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000) |
| "Delayed cerebral vasospasm after subarachnoid hemorrhage (SAH) may be evoked by the decreased availability of nitric oxide (NO)." | 1.34 | Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. ( Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M, 2007) |
| "The pathogenesis of cerebral vasospasm is likely to be multifactorial." | 1.32 | Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage. ( Böker, DK; Deinsberger, W; Woszczyk, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 16 (76.19) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, H | 1 |
| Reynolds, JD | 1 |
| Auten, RL | 1 |
| Demchenko, IT | 1 |
| Piantadosi, CA | 1 |
| Stamler, JS | 1 |
| Warner, DS | 1 |
| Fathi, AR | 1 |
| Pluta, RM | 3 |
| Bakhtian, KD | 1 |
| Qi, M | 1 |
| Lonser, RR | 1 |
| Shin, HK | 1 |
| Lee, JH | 1 |
| Kim, CD | 1 |
| Kim, YK | 1 |
| Hong, JY | 1 |
| Hong, KW | 1 |
| Woszczyk, A | 1 |
| Deinsberger, W | 1 |
| Böker, DK | 1 |
| Rejdak, K | 1 |
| Petzold, A | 1 |
| Sharpe, MA | 1 |
| Kay, AD | 1 |
| Kerr, M | 1 |
| Keir, G | 1 |
| Thompson, EJ | 1 |
| Giovannoni, G | 1 |
| Dejam, A | 1 |
| Grimes, G | 1 |
| Gladwin, MT | 1 |
| Oldfield, EH | 2 |
| Lin, CL | 1 |
| Hsu, YT | 1 |
| Lin, TK | 1 |
| Morrow, JD | 1 |
| Hsu, JC | 1 |
| Hsu, YH | 1 |
| Hsieh, TC | 1 |
| Tsay, PK | 1 |
| Yen, HC | 1 |
| Yatsushige, H | 1 |
| Calvert, JW | 1 |
| Cahill, J | 1 |
| Zhang, JH | 1 |
| Martens-Lobenhoffer, J | 1 |
| Sulyok, E | 1 |
| Czeiter, E | 1 |
| Büki, A | 1 |
| Kohl, J | 1 |
| Firsching, R | 1 |
| Tröger, U | 1 |
| Bode-Böger, SM | 1 |
| Jung, CS | 1 |
| Harvey-White, J | 1 |
| Espey, MG | 1 |
| Zimmermann, M | 1 |
| Seifert, V | 1 |
| Suzuki, Y | 1 |
| Osuka, K | 1 |
| Noda, A | 1 |
| Tanazawa, T | 1 |
| Takayasu, M | 1 |
| Shibuya, M | 1 |
| Yoshida, J | 1 |
| Suzuki, M | 1 |
| Asahara, H | 1 |
| Endo, S | 2 |
| Inada, K | 1 |
| Doi, M | 1 |
| Kuroda, K | 1 |
| Ogawa, A | 1 |
| Valenzuela, RF | 1 |
| Donoso, MV | 1 |
| Mellado, PA | 1 |
| Huidobro-Toro, JP | 1 |
| Sehba, FA | 1 |
| Schwartz, AY | 1 |
| Chereshnev, I | 1 |
| Bederson, JB | 1 |
| Staub, F | 1 |
| Graf, R | 1 |
| Gabel, P | 1 |
| Köchling, M | 1 |
| Klug, N | 1 |
| Heiss, WD | 1 |
| Takenaka, KV | 1 |
| Sakai, N | 1 |
| Murase, S | 1 |
| Kuroda, T | 1 |
| Okumura, A | 1 |
| Sawada, M | 1 |
| Sadamitsu, D | 1 |
| Kuroda, Y | 1 |
| Nagamitsu, T | 1 |
| Tsuruta, R | 1 |
| Inoue, T | 1 |
| Ueda, T | 1 |
| Nakashima, K | 1 |
| Ito, H | 1 |
| Maekawa, T | 1 |
| Khaldi, A | 2 |
| Zauner, A | 2 |
| Reinert, M | 2 |
| Woodward, JJ | 1 |
| Bullock, MR | 1 |
| Sakowitz, OW | 1 |
| Wolfrum, S | 1 |
| Sarrafzadeh, AS | 1 |
| Stover, JF | 1 |
| Dreier, JP | 1 |
| Dendorfer, A | 1 |
| Benndorf, G | 1 |
| Lanksch, WR | 1 |
| Unterberg, AW | 1 |
| Seiler, R | 1 |
| Bullock, R | 1 |
| Sakurai, Y | 1 |
| Sonobe, M | 1 |
| Suzuki, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2, Multi-Center, Open-label, Randomized, Parallel-Dose Study to Determine the Safety and Efficacy of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension (PAH)[NCT01725256] | Phase 2 | 29 participants (Actual) | Interventional | 2012-11-30 | Terminated (stopped due to Terminated early dt to acquisition of Sponsor and change in corporate priorities) | ||
| Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453] | 150 participants (Actual) | Observational | 2021-08-18 | Active, not recruiting | |||
| Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage[NCT05686265] | 32 participants (Anticipated) | Observational | 2023-05-11 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 other studies available for nitrites and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage.
Topics: Adjuvants, Pharmaceutic; Administration, Inhalation; Animals; Drug Synergism; Hemoglobins; Male; Mic | 2011 |
Reversal of cerebral vasospasm via intravenous sodium nitrite after subarachnoid hemorrhage in primates.
Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infusions, Intravenous; Macaca fascicularis; | 2011 |
Prevention of impairment of cerebral blood flow autoregulation during acute stage of subarachnoid hemorrhage by gene transfer of Cu/Zn SOD-1 to cerebral vessels.
Topics: Adenoviridae; Animals; Arteries; Blood Vessels; Cerebrovascular Circulation; Gene Expression; Gene T | 2003 |
Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage.
Topics: Adult; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Cisterna Magna; Female; Humans; Intra | 2003 |
Cerebrospinal fluid nitrite/nitrate correlated with oxyhemoglobin and outcome in patients with subarachnoid hemorrhage.
Topics: Adult; Aged; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Oxyhemoglobins; Pred | 2004 |
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.
Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infarction, Middle Cerebral Artery; Infusions | 2005 |
Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm; Antioxidants; Biomarkers; F2-Isoprostanes; Female; Humans; | 2006 |
Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Male; Nitrates | 2006 |
Determination of cerebrospinal fluid concentrations of arginine and dimethylarginines in patients with subarachnoid haemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Brain; Cerebrospinal Fluid; Female; Gas Chromatography-Mas | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In | 2007 |
Nitric oxide metabolites in the cisternal cerebral spinal fluid of patients with subarachnoid hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Cisterna Magna; Enzyme Induction; Female; Hemifacial Spasm; Humans; | 1997 |
Increased levels of nitrite/nitrate in the cerebrospinal fluid of patients with subarachnoid hemorrhage.
Topics: Humans; Nitrates; Nitric Oxide; Nitrites; Reference Values; Subarachnoid Hemorrhage; Vasospasm, Intr | 1999 |
Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF.
Topics: Adult; Biomarkers; Cerebrospinal Fluid Proteins; Chromogranin A; Chromogranins; Female; Humans; Male | 2000 |
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr | 2000 |
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr | 2000 |
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr | 2000 |
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr | 2000 |
Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhage.
Topics: Acute Disease; Adult; Aged; Aneurysm, Ruptured; Biomarkers; Brain; Catecholamines; Cerebrospinal Flu | 2000 |
Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Animals; Aorta, Thoracic; Cells, Cultured; Female; Gene Expression R | 2000 |
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites in postoperative patients with subarachnoid hemorrhage.
Topics: Adult; Analysis of Variance; Case-Control Studies; Female; Humans; Intracranial Aneurysm; Male; Midd | 2001 |
Measurement of nitric oxide and brain tissue oxygen tension in patients after severe subarachnoid hemorrhage.
Topics: Adult; Aged; Brain; Female; Humans; Male; Microdialysis; Middle Aged; Nitrates; Nitric Oxide; Nitrit | 2001 |
Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Fe | 2001 |
Microdialysis nitric oxide levels and brain tissue oxygen tension in patients with subarachnoid hemorrhage.
Topics: Brain; Energy Metabolism; Humans; Microdialysis; Nitrates; Nitric Oxide; Nitrites; Oxygen; Partial P | 2001 |
[Cerebral vasospasm caused by subarachnoid hemorrhage and its management, with special reference to the vasospastic effects of oxyhemoglobin].
Topics: Animals; Cats; Humans; Ischemic Attack, Transient; Nitrites; Oxyhemoglobins; Subarachnoid Hemorrhage | 1978 |