nitrites has been researched along with Shock, Septic in 112 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we report that (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one (DDP), a novel licochalcone B derivative compound, inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock." | 7.80 | (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one, a novel licochalcone B derivative compound, suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice. ( Jun, JG; Kim, JK; Park, JH, 2014) |
| "Monophosphoryl lipid A (MLA), a substructure of bacterial lipopolysaccharide (LPS), is being developed as a prophylactic for sepsis and septic shock." | 7.68 | A rationale for the prophylactic use of monophosphoryl lipid A in sepsis and septic shock. ( Gustafson, GL; Rhodes, MJ, 1992) |
| "Magnolol is a compound extracted from the Chinese medicinal herb Magnolia officinalis." | 5.36 | Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010) |
| " The in vivo anti-inflammatory effect of isoacteoside was determined using mouse models of xylene-induced ear oedema, LPS-induced endotoxic shock and LPS-induced endotoxaemia-associated acute kidney injury (AKI)." | 3.85 | Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization. ( Chen, X; Cui, Y; Gao, H; Kang, N; Li, J; Li, X; Liu, X; Liu, Y; Wang, C; Xu, QM; Yang, S; Zhang, Z; Zou, Y, 2017) |
| " Here, we report that (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one (DDP), a novel licochalcone B derivative compound, inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock." | 3.80 | (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one, a novel licochalcone B derivative compound, suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice. ( Jun, JG; Kim, JK; Park, JH, 2014) |
| "Monophosphoryl lipid A (MLA), a substructure of bacterial lipopolysaccharide (LPS), is being developed as a prophylactic for sepsis and septic shock." | 3.68 | A rationale for the prophylactic use of monophosphoryl lipid A in sepsis and septic shock. ( Gustafson, GL; Rhodes, MJ, 1992) |
| "Treatment with gentamicin stabilized cardiac index (BL, 5." | 2.71 | Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury. ( Enkhbaatar, P; Heggers, JP; Herndon, DN; Jodoin, JM; Maybauer, DM; Maybauer, MO; Morita, N; Traber, DL; Traber, LD; Westphal, M, 2005) |
| "Oxidative stress is implicated in septic shock." | 2.68 | The effects of intravenous antioxidants in patients with septic shock. ( Galley, HF; Howdle, PD; Walker, BE; Webster, NR, 1997) |
| "Severe sepsis and septic shock, which are among the most common causes of death in intensive care units worldwide, cause high morbidity, mortality, and social and economic costs." | 2.47 | Nitrite regulation of shock. ( Brouckaert, P; Cauwels, A, 2011) |
| "Among the 29 patients with septic shock, 18 cases (62." | 1.72 | The effect of preoperative urine culture and bacterial species on infection after percutaneous nephrolithotomy for patients with upper urinary tract stones. ( Cai, W; Hong, Y; Hu, M; Li, Q; Lin, D; Lin, J; Pan, H; Yang, Z; Ye, L, 2022) |
| "In a mouse model of LPS-induced septic shock, TCC inhibited the production of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, and increased survival by 83%." | 1.39 | The aerial part of Taraxacum coreanum extract has an anti-inflammatory effect on peritoneal macrophages in vitro and increases survival in a mouse model of septic shock. ( Bu, Y; Choi, HY; Ham, I; Kang, H; Kim, H; Lee, K; Lee, MH; Yang, G, 2013) |
| "Results Patients who developed septic shock (n = 35) had higher plasma NOx, total and free cortisol, and lower CBG concentrations than the nonseptic shock group (n = 27)." | 1.36 | Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels. ( Chapman, MJ; Edwards, J; Ho, JT; Lam, S; Lewis, JG; Ludbrook, G; O'Connor, S; Torpy, DJ, 2010) |
| "Magnolol is a compound extracted from the Chinese medicinal herb Magnolia officinalis." | 1.36 | Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010) |
| "We used an experimental model of endotoxic shock induced by LPS in mice in which the animals were pre-treated with ozone/oxygen mixture for 5 days (once daily), with injection of LPS 24 h thereafter to induce endotoxic shock." | 1.35 | Ozone oxidative preconditioning reduces nitrite levels in blood serum in LPS: induced endotoxic shock in mice. ( Alonso, Y; Alvarez, RG; Borrego, A; Delgado, R; Schulz, S; Zamora, ZB, 2009) |
| "mononuclears of patients with septic shock." | 1.33 | Differential inducible nitric oxide synthase activity in circulating neutrophils vs. mononuclears of septic shock patients. ( Cepinkas, G; Hersch, M; Izbicki, G; McCormack, D; Ostermann, M; Scott, JA; Sibbald, WJ, 2005) |
| "Treatment with ibuprofen, either before or after ETX, partly restored the elevated levels of nitrite/nitrate." | 1.33 | Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock. ( Akbulut, H; Ayar, A; Canbaz, M; Celik, I; Vural, P, 2005) |
| "Septic shock has a high mortality rate due to the hypotension and circulatory disorder that occurs during its pathogenesis." | 1.33 | Effects of verapamil and nifedipine on different parameters in lipopolysaccharide-induced septic shock. ( Erol, K; Kilic, FS; Sirmagul, B; Tunc, O; Yildirim, E, 2006) |
| "Patients with septic shock have a shortage in the availability of arginine associated with a slower production." | 1.33 | In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. ( Balasubramanyam, A; Bandi, VP; Gopal, J; Guntupalli, K; Jahoor, F; Villalpando, S, 2006) |
| "Recent findings in human septic shock suggest that glucocorticosteroids can limit and even reverse hemodynamic disturbances and dependence on catecholamines." | 1.32 | Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. ( Bollaert, PE; Levy, B; Longrois, D; Mallié, JP; Mansart, A; Seguin, C, 2003) |
| "In this acute endotoxic shock model, CVVH with the polyacrylonitrile membrane improved cardiac performance when compared with the polysulphone membrane." | 1.32 | Comparison of polyacrylonitrile (AN69) and polysulphone membrane during hemofiltration in canine endotoxic shock. ( Pauwels, D; Rogiers, P; Vincent, JL; Zhang, H, 2003) |
| "The mechanism of gut injury in endotoxic shock seems unrelated to hypoxia and release of nitric oxide." | 1.32 | Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia. ( De Backer, D; Dimopoulos, G; Lobo, SM; Nagy, N; Preiser, JC; Sun, Q; Terzi, RG; Tu, Z; Vercruy, V; Vincent, JL; Vray, B, 2003) |
| "Gram-positive septic shock was induced by coadministration of LTA (3 mg/kg i." | 1.31 | Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of gram-positive shock. ( Cuzzocrea, S; Foster, SJ; Olbrich, A; Thiemermann, C; Zacharowski, K, 2000) |
| "Sixteen patients admitted for septic shock." | 1.31 | Nitric oxide indices in human septic shock. ( Giercksky, KE; Kirkebøen, KA; Leone, A; Strand, OA, 2000) |
| "The incidence of sepsis and septic shock due to gram-positive organisms has increased dramatically over the last two decades." | 1.31 | A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the ra ( Foster, SJ; Hinds, CJ; Thiemermann, C; Wray, GM, 2001) |
| "To determine in children with sepsis syndrome and septic shock the time course of nitric oxide metabolites: nitrate and nitrite (nitrogen oxides)." | 1.30 | Activation of the L-arginine nitric oxide pathway in severe sepsis. ( Duke, T; South, M; Stewart, A, 1997) |
| "The best predictive value for septic shock was found to be the measurements of NO2-/NO3- and procalcitonin concentrations." | 1.30 | Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. ( Assicot, M; Baumgartner, JD; Bohuon, C; Chioléro, R; Corradin, SB; de Werra, I; Gallati, H; Glauser, MP; Heumann, D; Jaccard, C; Yersin, B, 1997) |
| "Patients diagnosed with septic shock had blood specimens taken on study entry and every 6 hrs for 72 hrs for methemoglobin and nitrite/nitrate determinations." | 1.30 | Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. ( Brilli, R; Denenberg, A; Krafte-Jacobs, B; Moore, L; Salzman, AL; Szabó, C, 1997) |
| "In brains from victims of Parkinson's disease, a nitrosyl species, identified as nitrosyl hemoglobin, has been observed in substantia nigra." | 1.30 | Applications of electron paramagnetic resonance spectroscopy to study interactions of iron proteins in cells with nitric oxide. ( Ananda Inalsingh, V; Cammack, R; Hughes, MN; Shergill, JK, 1998) |
| " Our results indicated that selected in vivo dosage regimens of DETC (intraperitoneal: at -2, -1, 3, 6, and 10 h or at -2, -1, 3, 6, 9, 12, 15, and 18 h relative to lipopolysaccharide administration, 180 mg/kg, at t = 0) in endotoxic mice were effective in increasing survival time when compared with untreated animals and DETC pretreatment was more effective than methylprednisolone (p<." | 1.30 | Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms. ( Fung, HL; Kishnani, NS; Tabrizi-Fard, MA, 1999) |
| " This investigation demonstrates that treatment with NO-inhalation, in order to prevent the dramatic increase in MPAP, PVR and the alterations in peripheral blood gases combined with systemic L-NMMAto improve systemic MABP and thus organ perfusion, may be a new therapeutic regimen in the treatment of septic shock." | 1.29 | Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock. ( Henning, R; Klemm, P; Martorana, PA; Thiemermann, C; Winklmaier, G, 1995) |
| "IL-1ra increases survival during endotoxic shock and attenuates production of TNF but not NO." | 1.29 | Maintenance of dynamic microvascular function and structure in a rat model of endotoxic shock by blockade of the interleukin-1 receptor. ( Baker, CH; Franz, MS; Norman, JG; Sutton, ET, 1995) |
| "Thirteen patients with septic shock were studied within 6 h after the development of hypotension." | 1.29 | Relationship between circulating levels of calcitonin gene-related peptide, nitric oxide metabolites and hemodynamic changes in human septic shock. ( Arnalich, F; Hernanz, A; Jiménez, M; López, J; Montiel, C; Tato, E; Vázquez, JJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 57 (50.89) | 18.2507 |
| 2000's | 42 (37.50) | 29.6817 |
| 2010's | 12 (10.71) | 24.3611 |
| 2020's | 1 (0.89) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Z | 1 |
| Lin, D | 1 |
| Hong, Y | 1 |
| Hu, M | 1 |
| Cai, W | 1 |
| Pan, H | 1 |
| Li, Q | 1 |
| Lin, J | 1 |
| Ye, L | 1 |
| Gao, H | 1 |
| Cui, Y | 1 |
| Kang, N | 1 |
| Liu, X | 1 |
| Liu, Y | 1 |
| Zou, Y | 1 |
| Zhang, Z | 1 |
| Li, X | 1 |
| Yang, S | 1 |
| Li, J | 1 |
| Wang, C | 1 |
| Xu, QM | 1 |
| Chen, X | 1 |
| Hansen, MB | 1 |
| Rasmussen, LS | 1 |
| Garred, P | 1 |
| Pilely, K | 1 |
| Wahl, AM | 1 |
| Perner, A | 1 |
| Madsen, MB | 1 |
| Hedegaard, ER | 1 |
| Simonsen, U | 1 |
| Hyldegaard, O | 1 |
| Park, JH | 1 |
| Jun, JG | 1 |
| Kim, JK | 1 |
| Shen, HH | 1 |
| Lam, KK | 1 |
| Cheng, PY | 2 |
| Kung, CW | 2 |
| Chen, SY | 1 |
| Lin, PC | 1 |
| Chung, MT | 1 |
| Lee, YM | 1 |
| Hagiwara, S | 1 |
| Iwasaka, H | 1 |
| Togo, K | 1 |
| Noguchi, T | 1 |
| Lobo, SM | 2 |
| Soriano, FG | 1 |
| Barbeiro, DF | 1 |
| De Backer, D | 2 |
| Sun, Q | 2 |
| Tu, Z | 3 |
| Dimopoulos, G | 2 |
| Preiser, JC | 3 |
| Vray, B | 2 |
| Vercruysse, V | 1 |
| Vincent, JL | 4 |
| Hauser, B | 1 |
| Barth, E | 1 |
| Bassi, G | 1 |
| Simon, F | 1 |
| Gröger, M | 1 |
| Oter, S | 1 |
| Speit, G | 1 |
| Ploner, F | 1 |
| Möller, P | 1 |
| Wachter, U | 1 |
| Vogt, JA | 1 |
| Matejovic, M | 1 |
| Calzia, E | 1 |
| Georgieff, M | 1 |
| Radermacher, P | 1 |
| Maybauer, DM | 4 |
| Alvarez, RG | 1 |
| Zamora, ZB | 1 |
| Borrego, A | 1 |
| Delgado, R | 1 |
| Schulz, S | 1 |
| Alonso, Y | 1 |
| Khemiri, M | 1 |
| Labassi, A | 1 |
| Tlili, Y | 1 |
| Barsaoui, S | 1 |
| Ho, JT | 1 |
| Chapman, MJ | 1 |
| O'Connor, S | 1 |
| Lam, S | 1 |
| Edwards, J | 1 |
| Ludbrook, G | 1 |
| Lewis, JG | 1 |
| Torpy, DJ | 1 |
| Tsai, YC | 1 |
| Peng, YJ | 1 |
| Ke, TH | 1 |
| Wang, JJ | 3 |
| Yen, MH | 2 |
| Cauwels, A | 1 |
| Brouckaert, P | 1 |
| Del Angel-Meza, AR | 1 |
| Dávalos-Marín, AJ | 1 |
| Ontiveros-Martinez, LL | 1 |
| Ortiz, GG | 1 |
| Beas-Zarate, C | 1 |
| Chaparro-Huerta, V | 1 |
| Torres-Mendoza, BM | 1 |
| Bitzer-Quintero, OK | 1 |
| Ji, M | 1 |
| Li, R | 1 |
| Li, GM | 1 |
| Fan, Y | 1 |
| Dong, L | 1 |
| Yang, J | 1 |
| Peng, YG | 1 |
| Wu, J | 2 |
| Kothari, N | 1 |
| Bogra, J | 1 |
| Kohli, M | 1 |
| Malik, A | 1 |
| Kothari, D | 1 |
| Srivastava, S | 1 |
| Keshari, RS | 1 |
| Singh, V | 1 |
| Barthwal, MK | 1 |
| Dikshit, M | 1 |
| Bony, E | 1 |
| Boudard, F | 1 |
| Dussossoy, E | 1 |
| Portet, K | 1 |
| Brat, P | 1 |
| Giaimis, J | 1 |
| Michel, A | 1 |
| Lee, MH | 1 |
| Kang, H | 1 |
| Lee, K | 1 |
| Yang, G | 1 |
| Ham, I | 1 |
| Bu, Y | 1 |
| Kim, H | 1 |
| Choi, HY | 1 |
| Mansart, A | 1 |
| Bollaert, PE | 1 |
| Seguin, C | 1 |
| Levy, B | 1 |
| Longrois, D | 1 |
| Mallié, JP | 1 |
| Rogiers, P | 1 |
| Zhang, H | 2 |
| Pauwels, D | 1 |
| Nagy, N | 1 |
| Vercruy, V | 1 |
| Terzi, RG | 1 |
| Engin, A | 1 |
| Kurukahvecioğlu, O | 1 |
| Bukan, N | 1 |
| Dursun, A | 1 |
| Tsao, CM | 2 |
| Ho, ST | 2 |
| Chen, A | 3 |
| Tsai, SK | 2 |
| Wu, CC | 6 |
| Hsiao, G | 2 |
| Huang, HY | 1 |
| Fong, TH | 1 |
| Shen, MY | 1 |
| Lin, CH | 1 |
| Teng, CM | 1 |
| Sheu, JR | 1 |
| Li, CY | 1 |
| Tissier, S | 1 |
| Lancel, S | 2 |
| Marechal, X | 1 |
| Mordon, S | 1 |
| Depontieu, F | 1 |
| Scherpereel, A | 1 |
| Chopin, C | 1 |
| Neviere, R | 2 |
| Mitaka, C | 1 |
| Connelly, L | 1 |
| Madhani, M | 1 |
| Hobbs, AJ | 1 |
| Lin, HC | 1 |
| Wan, FJ | 1 |
| Tung, CS | 1 |
| Wu, TH | 1 |
| Hersch, M | 1 |
| Scott, JA | 1 |
| Izbicki, G | 1 |
| McCormack, D | 1 |
| Cepinkas, G | 1 |
| Ostermann, M | 1 |
| Sibbald, WJ | 1 |
| Lanone, S | 1 |
| Bloc, S | 1 |
| Foresti, R | 1 |
| Almolki, A | 1 |
| Taillé, C | 1 |
| Callebert, J | 1 |
| Conti, M | 1 |
| Goven, D | 1 |
| Aubier, M | 1 |
| Dureuil, B | 1 |
| El-Benna, J | 1 |
| Motterlini, R | 1 |
| Boczkowski, J | 1 |
| Maybauer, MO | 3 |
| Traber, LD | 3 |
| Westphal, M | 3 |
| Enkhbaatar, P | 4 |
| Morita, N | 2 |
| Jodoin, JM | 1 |
| Heggers, JP | 1 |
| Herndon, DN | 3 |
| Traber, DL | 3 |
| Akbulut, H | 1 |
| Celik, I | 1 |
| Ayar, A | 1 |
| Vural, P | 1 |
| Canbaz, M | 1 |
| Cirioni, O | 1 |
| Giacometti, A | 1 |
| Ghiselli, R | 1 |
| Bergnach, C | 1 |
| Orlando, F | 1 |
| Silvestri, C | 1 |
| Mocchegiani, F | 1 |
| Licci, A | 1 |
| Skerlavaj, B | 1 |
| Rocchi, M | 1 |
| Saba, V | 1 |
| Zanetti, M | 1 |
| Scalise, G | 1 |
| Sirmagul, B | 1 |
| Kilic, FS | 1 |
| Tunc, O | 1 |
| Yildirim, E | 1 |
| Erol, K | 1 |
| Joulin, O | 1 |
| Petillot, P | 1 |
| Labalette, M | 1 |
| Villalpando, S | 1 |
| Gopal, J | 1 |
| Balasubramanyam, A | 1 |
| Bandi, VP | 1 |
| Guntupalli, K | 1 |
| Jahoor, F | 1 |
| Nakano, YY | 2 |
| Anuar, F | 1 |
| Whiteman, M | 1 |
| Bhatia, M | 1 |
| Moore, PK | 1 |
| Sakaguchi, S | 1 |
| Furusawa, S | 1 |
| Nagata, K | 1 |
| Chatterjee, S | 1 |
| Premachandran, S | 1 |
| Shukla, J | 1 |
| Poduval, TB | 1 |
| Kikuchi, M | 2 |
| Endo, S | 5 |
| Inada, K | 5 |
| Inoue, Y | 1 |
| Wakabayashi, G | 2 |
| Ishikura, H | 2 |
| Tanaka, T | 2 |
| Fraser, JF | 1 |
| Cox, RA | 1 |
| Huda, R | 1 |
| Hawkins, HK | 1 |
| Laubach, VE | 1 |
| Shesely, EG | 1 |
| Smithies, O | 1 |
| Sherman, PA | 1 |
| Evans, T | 2 |
| Carpenter, A | 2 |
| Silva, A | 1 |
| Cohen, J | 2 |
| Wachel, D | 1 |
| Boeynaems, JM | 1 |
| Buurman, W | 1 |
| Kida, T | 1 |
| Kuroki, T | 1 |
| Kobayashi, K | 1 |
| Inoue, M | 1 |
| Klemm, P | 2 |
| Thiemermann, C | 7 |
| Winklmaier, G | 1 |
| Martorana, PA | 1 |
| Henning, R | 1 |
| Vane, JR | 2 |
| Hecker, M | 1 |
| Stockhausen, H | 1 |
| Norman, JG | 2 |
| Sutton, ET | 2 |
| Franz, MS | 1 |
| Baker, CH | 1 |
| Komarov, AM | 1 |
| Lai, CS | 1 |
| Martín, MC | 2 |
| Gómez-Jiménez, J | 2 |
| Esteban, F | 1 |
| Saurí, R | 1 |
| Mourelle, MI | 1 |
| Salgado, A | 2 |
| Mourelle, M | 1 |
| Segura, RM | 1 |
| Peracaula, R | 1 |
| Moncada, S | 3 |
| Castillo, L | 1 |
| Horton, RA | 1 |
| Ceppi, ED | 2 |
| Knowles, RG | 1 |
| Titheradge, MA | 2 |
| Kinderman, H | 1 |
| Molina, L | 1 |
| Studenberg, S | 1 |
| Wolberg, G | 1 |
| Kazmierski, W | 1 |
| Wilson, J | 1 |
| Tadepalli, A | 1 |
| Chang, AC | 1 |
| Kosanke, S | 1 |
| Hinshaw, L | 1 |
| Smith, FS | 1 |
| De Kimpe, SJ | 1 |
| Paya, D | 1 |
| Maupoil, V | 1 |
| Schott, C | 1 |
| Rochette, L | 1 |
| Stoclet, JC | 1 |
| Nakae, H | 4 |
| Yaegashi, Y | 1 |
| Takakuwa, T | 2 |
| Yamada, Y | 4 |
| Arakawa, N | 2 |
| Suzuki, T | 2 |
| Taniguchi, S | 3 |
| Shimamura, T | 2 |
| Ogawa, M | 2 |
| Teraoka, H | 1 |
| Maestroni, GJ | 1 |
| Yoshida, M | 1 |
| Seo, HG | 1 |
| Fujiwara, N | 1 |
| Kaneto, H | 1 |
| Asahi, M | 1 |
| Fujii, J | 1 |
| Taniguchi, N | 1 |
| Szabó, C | 3 |
| Bryk, R | 1 |
| Zingarelli, B | 4 |
| Southan, GJ | 1 |
| Gahman, TC | 1 |
| Bhat, V | 1 |
| Salzman, AL | 3 |
| Wolff, DJ | 1 |
| Arnalich, F | 1 |
| Hernanz, A | 1 |
| Jiménez, M | 1 |
| López, J | 1 |
| Tato, E | 1 |
| Vázquez, JJ | 1 |
| Montiel, C | 1 |
| Strohmaier, W | 1 |
| Werner, ER | 1 |
| Wachter, H | 1 |
| Redl, H | 1 |
| Schlag, G | 1 |
| Newton, CA | 1 |
| Hellermann, GR | 1 |
| Richards, IS | 1 |
| Duke, T | 1 |
| South, M | 1 |
| Stewart, A | 1 |
| de Werra, I | 1 |
| Jaccard, C | 1 |
| Corradin, SB | 1 |
| Chioléro, R | 1 |
| Yersin, B | 1 |
| Gallati, H | 1 |
| Assicot, M | 1 |
| Bohuon, C | 1 |
| Baumgartner, JD | 1 |
| Glauser, MP | 1 |
| Heumann, D | 1 |
| Spack, L | 1 |
| Havens, PL | 1 |
| Griffith, OW | 1 |
| Krafte-Jacobs, B | 1 |
| Brilli, R | 1 |
| Denenberg, A | 1 |
| Moore, L | 1 |
| Galley, HF | 1 |
| Howdle, PD | 1 |
| Walker, BE | 1 |
| Webster, NR | 1 |
| Yu, SM | 1 |
| Wu, JF | 1 |
| Lin, TL | 1 |
| Kuo, SC | 1 |
| Hattori, Y | 2 |
| Akimoto, K | 1 |
| Nakanishi, N | 2 |
| Kasai, K | 2 |
| Doughty, L | 1 |
| Carcillo, JA | 1 |
| Kaplan, S | 1 |
| Janosky, J | 1 |
| Mustafa, SB | 1 |
| Olson, MS | 1 |
| Ikejima, K | 1 |
| Enomoto, N | 1 |
| Iimuro, Y | 1 |
| Ikejima, A | 1 |
| Fang, D | 1 |
| Xu, J | 1 |
| Forman, DT | 1 |
| Brenner, DA | 1 |
| Thurman, RG | 1 |
| Wray, GM | 2 |
| Millar, CG | 1 |
| Hinds, CJ | 2 |
| Avontuur, JA | 3 |
| Biewenga, M | 1 |
| Buijk, SL | 1 |
| Kanhai, KJ | 1 |
| Bruining, HA | 3 |
| Rees, DD | 1 |
| Monkhouse, JE | 1 |
| Cambridge, D | 1 |
| Demitri, MT | 1 |
| Benigni, F | 1 |
| Meazza, C | 1 |
| Zinetti, M | 1 |
| Fratelli, M | 1 |
| Villa, P | 1 |
| Acheson, A | 1 |
| Panayotatos, N | 1 |
| Ghezzi, P | 1 |
| Stam, TC | 1 |
| Jongen-Lavrencic, M | 1 |
| van Amsterdam, JG | 1 |
| Eggermont, AM | 1 |
| Kamei, Y | 1 |
| Minato, T | 1 |
| Yokoyama, M | 2 |
| Baker, JE | 1 |
| Holman, P | 1 |
| Kalyanaraman, B | 1 |
| Pritchard, KA | 1 |
| Boomsma, F | 1 |
| van den Meiracker, AH | 1 |
| de Jong, FH | 1 |
| Cammack, R | 1 |
| Shergill, JK | 1 |
| Ananda Inalsingh, V | 1 |
| Hughes, MN | 1 |
| ter Steege, JC | 1 |
| Forget, PP | 1 |
| Buurman, WA | 1 |
| Mehta, S | 1 |
| Javeshghani, D | 1 |
| Datta, P | 1 |
| Levy, RD | 1 |
| Magder, S | 1 |
| Groeneveld, AB | 1 |
| Hartemink, KJ | 1 |
| de Groot, MC | 1 |
| Visser, J | 1 |
| Thijs, LG | 1 |
| Kishnani, NS | 1 |
| Tabrizi-Fard, MA | 1 |
| Fung, HL | 1 |
| Kang, KW | 1 |
| Pak, YM | 1 |
| Kim, ND | 1 |
| Ogura, S | 1 |
| Umegaki, O | 1 |
| Genovese, F | 1 |
| Fernando, LP | 1 |
| Cochran, JB | 1 |
| Romeo, CM | 1 |
| Cook, JA | 2 |
| Haskó, G | 1 |
| Gross, SS | 1 |
| Yamashita, T | 1 |
| Kawashima, S | 1 |
| Ohashi, Y | 1 |
| Ozaki, M | 1 |
| Ueyama, T | 1 |
| Ishida, T | 1 |
| Inoue, N | 1 |
| Hirata, K | 1 |
| Akita, H | 1 |
| Chen, CP | 1 |
| Yokozawa, T | 1 |
| Kitani, K | 1 |
| Shimohashi, N | 1 |
| Nakamuta, M | 1 |
| Uchimura, K | 1 |
| Sugimoto, R | 1 |
| Iwamoto, H | 1 |
| Enjoji, M | 1 |
| Nawata, H | 1 |
| Zacharowski, K | 1 |
| Olbrich, A | 1 |
| Cuzzocrea, S | 1 |
| Foster, SJ | 2 |
| Shibata, M | 1 |
| Kawamura, T | 1 |
| Sato, S | 1 |
| Strand, OA | 1 |
| Leone, A | 1 |
| Giercksky, KE | 1 |
| Kirkebøen, KA | 1 |
| Bian, Z | 1 |
| Yan, ZQ | 1 |
| Hansson, GK | 1 |
| Thorén, P | 1 |
| Normark, S | 1 |
| MacKenzie, IM | 1 |
| Garrard, CS | 1 |
| Young, JD | 1 |
| Chiao, CW | 1 |
| Okajima, K | 1 |
| Uchiba, M | 1 |
| Isobe, H | 1 |
| Okabe, H | 1 |
| Kang, YJ | 1 |
| Seo, SJ | 1 |
| Yun-Choi, HS | 1 |
| Lee, DH | 1 |
| Kim, YM | 1 |
| Chang, KC | 1 |
| Sheehan, M | 1 |
| Wong, HR | 1 |
| Hake, PW | 2 |
| Nava, E | 1 |
| Palmer, RM | 1 |
| Gustafson, GL | 1 |
| Rhodes, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Natural History of Procalcitonin in Hemorrhagic Stroke[NCT01498705] | 0 participants (Actual) | Observational | 2011-12-31 | Withdrawn (stopped due to Anticipated grant was withdrawn and additional funding was unable to be obtained) | |||
| Effect of Intravenous Vitamin C on Sequential Organ Failure Assessment (SOFA) Score Among Septic Patients: Randomized Controlled Trial[NCT04137276] | 33 participants (Actual) | Interventional | 2019-04-01 | Completed | |||
| Zinc and Inflammation in Sepsis[NCT01328509] | 39 participants (Actual) | Observational | 2012-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for nitrites and Shock, Septic
| Article | Year |
|---|---|
Severe toxic methemoglobinemia mimicking septic shock in an infant.
Topics: Ascorbic Acid; Cyanosis; Daucus carota; Diagnosis, Differential; Dyspnea; Emergency Treatment; Human | 2009 |
Nitrite regulation of shock.
Topics: Animals; Humans; Mitochondria; Multiple Organ Failure; Nitric Oxide; Nitrites; Shock, Septic; Tumor | 2011 |
[Septic shock and NO].
Topics: Animals; Biomarkers; Guanidines; Guanylate Cyclase; Hemodynamics; Humans; Methylene Blue; Nitrates; | 2004 |
6 trials available for nitrites and Shock, Septic
| Article | Year |
|---|---|
Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine With Morbidity and Mortality in Patients With Necrotizing Soft Tissue Infections.
Topics: Adult; Aged; Arginine; Biomarkers; Disease-Free Survival; Female; Hospital Mortality; Humans; Male; | 2018 |
Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury.
Topics: Animals; Arteries; Blood Pressure; Female; Gentamicins; Hemodynamics; Lung; Nitrates; Nitric Oxide; | 2005 |
Nitrite/nitrate oxide (NOx) and cytokine levels in patients with septic shock.
Topics: Cytokines; Endotoxins; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-6; Interleukin | 1996 |
The effects of intravenous antioxidants in patients with septic shock.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combinati | 1997 |
The effects of intravenous antioxidants in patients with septic shock.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combinati | 1997 |
The effects of intravenous antioxidants in patients with septic shock.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combinati | 1997 |
The effects of intravenous antioxidants in patients with septic shock.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combinati | 1997 |
Effect of L-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNF alpha and nitrite/nitrate in human septic shock.
Topics: APACHE; Drug Monitoring; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-6; Interl | 1998 |
Circulating endothelin and nitrate-nitrite relate to hemodynamic and metabolic variables in human septic shock.
Topics: Adult; Aged; Aged, 80 and over; Blood Vessels; Cardiotonic Agents; Creatinine; Cytokines; Dopamine; | 1999 |
103 other studies available for nitrites and Shock, Septic
| Article | Year |
|---|---|
The effect of preoperative urine culture and bacterial species on infection after percutaneous nephrolithotomy for patients with upper urinary tract stones.
Topics: Aged; Bacterial Infections; Enterococcus faecium; Escherichia coli; Escherichia coli Infections; Fem | 2022 |
Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooxygenase 2; Cytokines | 2017 |
(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one, a novel licochalcone B derivative compound, suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chalcones; Interleukin-1beta; Interleuk | 2014 |
Alpha-lipoic acid prevents endotoxic shock and multiple organ dysfunction syndrome induced by endotoxemia in rats.
Topics: Animals; Antioxidants; Antithrombins; Aorta; Caspase 3; Disulfides; Endotoxemia; Enzyme Activation; | 2015 |
A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.
Topics: Animals; Glycine; HMGB1 Protein; Interleukin-6; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung | 2008 |
Effects of dobutamine on gut mucosal nitric oxide production during endotoxic shock in rabbits.
Topics: Animals; Coronary Circulation; Dobutamine; Heart Rate; Intestinal Mucosa; Lactic Acid; Lipopolysacch | 2009 |
Hemodynamic, metabolic, and organ function effects of pure oxygen ventilation during established fecal peritonitis-induced septic shock.
Topics: Animals; Apoptosis; Biomarkers; Comet Assay; Dinoprost; DNA Damage; Nitrates; Nitrites; Oxidative St | 2009 |
Ozone oxidative preconditioning reduces nitrite levels in blood serum in LPS: induced endotoxic shock in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Lipopolysaccharides; Male; Mice; Mi | 2009 |
Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels.
Topics: Analysis of Variance; Dobutamine; Epinephrine; Female; Humans; Hydrocortisone; Intensive Care Units; | 2010 |
Beneficial effects of magnolol in a rodent model of endotoxin shock.
Topics: Animals; Antithrombin III; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Gene Expressi | 2010 |
Protective effects of tryptophan on neuro-inflammation in rats after administering lipopolysaccharide.
Topics: Animals; Antioxidants; Cerebral Cortex; Drug Interactions; Female; Free Radical Scavengers; Hippocam | 2011 |
Effects of combined levosimendan and vasopressin on pulmonary function in porcine septic shock.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Drug Therapy, Combination; Female; Hemodynamics; HMG- | 2012 |
Role of active nitrogen molecules in progression of septic shock.
Topics: Adult; APACHE; Creatinine; Critical Care; Critical Illness; Disease Progression; Enzyme-Linked Immun | 2012 |
Chemical composition and anti-inflammatory properties of the unsaponifiable fraction from awara (Astrocaryum vulgare M.) pulp oil in activated J774 macrophages and in a mice model of endotoxic shock.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arecaceae; Carotenoids; Cell Line; Cyclooxygenase 1 | 2012 |
The aerial part of Taraxacum coreanum extract has an anti-inflammatory effect on peritoneal macrophages in vitro and increases survival in a mouse model of septic shock.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyt | 2013 |
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response Relatio | 2003 |
Comparison of polyacrylonitrile (AN69) and polysulphone membrane during hemofiltration in canine endotoxic shock.
Topics: Acrylic Resins; Animals; Bicarbonates; Biocompatible Materials; Dogs; Endotoxins; Escherichia coli; | 2003 |
Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.
Topics: Animals; Blood Pressure; Carbon Dioxide; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Lipopolysa | 2003 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Func | 2003 |
Propofol ameliorates liver dysfunction and inhibits aortic superoxide level in conscious rats with endotoxic shock.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Endotoxins; Escherichia coli; Heart Rate; Kidn | 2003 |
Inhibitory mechanisms of YC-1 and PMC in the induction of iNOS expression by lipoteichoic acid in RAW 264.7 macrophages.
Topics: Animals; Chromans; Drug Interactions; Enzyme Activation; Gene Expression; Indazoles; Lipopolysacchar | 2004 |
Low-dose dexamethasone ameliorates circulatory failure and renal dysfunction in conscious rats with endotoxemia.
Topics: Animals; Arteries; Blood Pressure; Blotting, Western; Calcium; Dexamethasone; Endotoxemia; Escherich | 2004 |
Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats.
Topics: Animals; Cardiomyopathies; Endotoxins; Glycoproteins; Heart; In Vitro Techniques; Inflammation; Inje | 2004 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cy | 2005 |
Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanid | 2005 |
Differential inducible nitric oxide synthase activity in circulating neutrophils vs. mononuclears of septic shock patients.
Topics: Hospitals, University; Humans; Intensive Care Units; Leukocytes, Mononuclear; Neutrophils; Nitrates; | 2005 |
Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats.
Topics: Animals; Antioxidants; Aorta; Bilirubin; Blood Pressure; Blotting, Western; Cell Line; Down-Regulati | 2005 |
Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypotension; Ibuprofen; | 2005 |
LL-37 protects rats against lethal sepsis caused by gram-negative bacteria.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cathelicidins; Cecum; Disease Model | 2006 |
Effects of verapamil and nifedipine on different parameters in lipopolysaccharide-induced septic shock.
Topics: Animals; Calcium Channel Blockers; Carotid Arteries; Catalase; Disease Models, Animal; Interleukin-1 | 2006 |
Cytokine profile of human septic shock serum inducing cardiomyocyte contractile dysfunction.
Topics: Adolescent; Animals; Cytokines; Humans; Myocardial Contraction; Myocytes, Cardiac; Nitrates; Nitrite | 2007 |
In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis.
Topics: Adult; Aged; Arginine; Case-Control Studies; Critical Illness; Female; Glomerular Filtration Rate; H | 2006 |
Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Lung; Microcirculation; Multipl | 2006 |
Flurbiprofen and its nitric oxide-releasing derivative protect against septic shock in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cecum; Disease Models, Animal; Flu | 2006 |
Preventive effects of a biscoclaurine alkaloid, cepharanthine, on endotoxin or tumor necrosis factor-alpha-induced septic shock symptoms: involvement of from cell death in L929 cells and nitric oxide production in raw 264.7 cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Cell Death; Cell Line; Endotoxins; Male; Mice; Mice, Inbred | 2007 |
Synergistic therapeutic potential of dexamethasone and L-arginine in lipopolysaccharide-induced septic shock.
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Cytokines; Dexametha | 2007 |
Assessment of inflammatory mediators in patients with generalized peritonitis.
Topics: Adult; Aged; Aged, 80 and over; Cytokines; Endotoxins; Female; Group IV Phospholipases A2; Humans; I | 1999 |
Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock.
Topics: Animals; Anti-Bacterial Agents; Blood Pressure; Ceftazidime; Disease Models, Animal; Female; Heart R | 2007 |
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
Topics: Animals; Base Sequence; Disease Models, Animal; Drug Resistance; Immunoblotting; Interferon-gamma; L | 1995 |
Inhibition of nitric oxide synthase in experimental gram-negative sepsis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli; Escherichia coli Infections; Liver; | 1994 |
Is endotoxin-induced hypotension related to nitric oxide formation?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates | 1994 |
Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Dexamethasone; Enz | 1994 |
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock.
Topics: Administration, Inhalation; Amino Acid Oxidoreductases; Animals; Arginine; Blood Gas Analysis; Esche | 1995 |
Glibenclamide-induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anaesthetized rat.
Topics: Amino Acid Oxidoreductases; Anesthetics; Animals; Cell Line; Endotoxins; Enzyme Induction; Glyburide | 1995 |
Inhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat.
Topics: Anesthesia; Animals; Cell Line; Culture Media, Conditioned; Hemodynamics; Interferon-gamma; Lipopoly | 1995 |
Maintenance of dynamic microvascular function and structure in a rat model of endotoxic shock by blockade of the interleukin-1 receptor.
Topics: Acetylcholine; Animals; Aorta; Arterioles; Blood Pressure; Endothelium, Vascular; Endotoxins; Hemody | 1995 |
Detection of nitric oxide production in mice by spin-trapping electron paramagnetic resonance spectroscopy.
Topics: Animals; Arginine; Chelating Agents; Electron Spin Resonance Spectroscopy; Female; Ferrous Compounds | 1995 |
[Cytokines and nitric oxide in streptococcal toxic shock syndrome].
Topics: Adult; Cytokines; Endotoxins; Female; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Male; Mid | 1995 |
L-arginine: nitric oxide pathway in endotoxemia and human septic shock.
Topics: Arginine; Cardiac Output; Creatinine; Endotoxins; Female; Humans; Kidney; Male; Nitrates; Nitric Oxi | 1995 |
Sources of nitrates and nitrites in neonates with sepsis.
Topics: Humans; Infant, Newborn; Nitrates; Nitric Oxide; Nitrites; Shock, Septic | 1994 |
Inhibition of hepatic gluconeogenesis by nitric oxide: a comparison with endotoxic shock.
Topics: Animals; Dihydroxyacetone; Endotoxins; Fructose; Gluconeogenesis; Glycerol; Lactates; Liver; Male; M | 1994 |
Evidence of increased nitric oxide production in patients with the sepsis syndrome.
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Female; Humans; Hypotension; Male; Middle Aged; | 1993 |
Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Free Radical Scaveng | 1996 |
Effect of multiple cytokines plus bacterial endotoxin on glucose and nitric oxide production by cultured hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Enzyme Inhibitors; Glucose; Lipopo | 1996 |
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock.
Topics: Acute Kidney Injury; Animals; Azepines; Cells, Cultured; Diterpenes; Ginkgolides; Hemodynamics; Lact | 1995 |
Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; In Vitro Techniques; Lipopolysaccharides; Male; Muscl | 1995 |
Nitrite/nitrate (NOX) and type II phospholipase A2, leukotriene B4, and platelet-activating factor levels in patients with septic shock.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Group II Phospholipases A2; Humans; Leu | 1996 |
Melatonin as a therapeutic agent in experimental endotoxic shock.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Escherichia coli; Female; L | 1996 |
Effect of a nitric oxide synthase inhibitor, S-ethylisothiourea, on cultured cells and cardiovascular functions of normal and lipopolysaccharide-treated rabbits.
Topics: Animals; Blood Pressure; Brain; Cells, Cultured; Citrulline; Colforsin; DNA; Dose-Response Relations | 1996 |
Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cell Line; Cell Respiration; Enzyme Induction; Enzyme Inhi | 1996 |
Relationship between circulating levels of calcitonin gene-related peptide, nitric oxide metabolites and hemodynamic changes in human septic shock.
Topics: Adult; Calcitonin Gene-Related Peptide; Hemodynamics; Humans; Middle Aged; Nitrates; Nitric Oxide; N | 1996 |
Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock.
Topics: Animals; Arteries; Cardiac Output; Creatinine; Disease Models, Animal; Escherichia coli Infections; | 1996 |
Endothelial structural integrity is maintained during endotoxic shock in an interleukin-1 type 1 receptor knockout mouse.
Topics: Animals; Endothelium, Vascular; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitra | 1997 |
Activation of the L-arginine nitric oxide pathway in severe sepsis.
Topics: Adolescent; Arginine; Biomarkers; Child; Child, Preschool; Female; Humans; Infant; Male; Multiple Or | 1997 |
Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Cohort Stud | 1997 |
Measurements of total plasma nitrite and nitrate in pediatric patients with the systemic inflammatory response syndrome.
Topics: Child, Preschool; Cohort Studies; Humans; Infant; Infant, Newborn; Nitrates; Nitrites; Predictive Va | 1997 |
Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock.
Topics: Adolescent; Biomarkers; Blood Gas Analysis; Case-Control Studies; Child; Child, Preschool; Female; H | 1997 |
Inhibition of nitric oxide synthase expression by PPM-18, a novel anti-inflammatory agent, in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; DNA-Binding Proteins; Dose-Response Relationship, | 1997 |
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of endotoxic shock.
Topics: Adrenalectomy; Animals; Biopterins; Dexamethasone; Disease Models, Animal; Enzyme Induction; Escheri | 1997 |
Plasma nitrite and nitrate concentrations and multiple organ failure in pediatric sepsis.
Topics: Adolescent; Bacteremia; Child; Child, Preschool; Follow-Up Studies; Humans; Infant; Infant, Newborn; | 1998 |
Expression of nitric-oxide synthase in rat Kupffer cells is regulated by cAMP.
Topics: Animals; Biological Transport; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cytoplasm; DNA- | 1998 |
Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin.
Topics: Acute-Phase Proteins; Animals; Calcium; Carrier Proteins; Endotoxins; Estrogens; Female; Injections, | 1998 |
Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin.
Topics: Amidines; Animals; Benzylamines; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Kidney; Lipopoly | 1998 |
Pulmonary hypertension and reduced cardiac output during inhibition of nitric oxide synthesis in human septic shock.
Topics: Aged; Cardiac Output; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension, Pulmonary; Male; NG-Nit | 1998 |
Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Enzyme Inhibitors; Female; Hemodynamics; Interle | 1998 |
Protective effect of ciliary neurotrophic factor (CNTF) in a model of endotoxic shock: action mechanisms and role of CNTF receptor alpha.
Topics: Adrenalectomy; Animals; Ciliary Neurotrophic Factor; Disease Models, Animal; Humans; Lipopolysacchar | 1998 |
Plasma levels of type II phospholipase A2 and nitrite/nitrate in patients with burns.
Topics: Adult; Aged; Biomarkers; Burns; Enzyme-Linked Immunosorbent Assay; Female; Group II Phospholipases A | 1998 |
Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Topics: Aging; Animals; Cyclic GMP; Gene Expression Regulation, Developmental; Gene Expression Regulation, E | 1998 |
Endothelin-1 and blood pressure after inhibition of nitric oxide synthesis in human septic shock.
Topics: Blood Pressure; Endothelin-1; Female; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitr | 1999 |
Applications of electron paramagnetic resonance spectroscopy to study interactions of iron proteins in cells with nitric oxide.
Topics: Animals; Bacteria; Cysteine; Electron Spin Resonance Spectroscopy; Food Preservation; Hemeproteins; | 1998 |
Oral spermine administration inhibits nitric oxide-mediated intestinal damage and levels of systemic inflammatory mediators in a mouse endotoxin model.
Topics: Administration, Oral; Animals; Disease Models, Animal; Escherichia coli; Female; Immunohistochemistr | 1999 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Mod | 1999 |
Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms.
Topics: Animals; Chelating Agents; Collagenases; Ditiocarb; Dose-Response Relationship, Drug; Female; Gelati | 1999 |
Diethylmaleate and buthionine sulfoximine, glutathione-depleting agents, differentially inhibit expression of inducible nitric oxide synthase in endotoxemic mice.
Topics: Animals; Buthionine Sulfoximine; Gene Expression Regulation, Enzymologic; Glutathione; Interleukin-1 | 1999 |
Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase 2; Endotoxins; Gram-Posi | 1999 |
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
Topics: Animals; Aorta; Cell Respiration; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Te | 1999 |
Adrenomedullin augments nitric oxide and tetrahydrobioptein synthesis in cytokine-stimulated vascular smooth muscle cells.
Topics: Adrenomedullin; Analysis of Variance; Animals; Antioxidants; Biopterins; Cells, Cultured; Enzyme Act | 1999 |
Resistance to endotoxin shock in transgenic mice overexpressing endothelial nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Cyclic GMP; Edema; Female; Granulocytes; Hypotension; Immunity, Inna | 2000 |
Beneficial effects of sanguisorbae radix in renal dysfunction caused by endotoxin in vivo.
Topics: Animals; Blood Urea Nitrogen; Creatine; Drugs, Chinese Herbal; Endotoxins; Male; Nitrates; Nitric Ox | 1999 |
Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-alpha production by the modulation of jun-N-terminal kinase and the NF-kappab signaling pathway in rat Kupffer cells.
Topics: Animals; Antioxidants; Azoles; Blotting, Western; Cell Nucleus; Cells, Cultured; Cyclooxygenase 1; C | 2000 |
Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of gram-positive shock.
Topics: Animals; Blood Pressure; Cyclic N-Oxides; Free Radical Scavengers; Kidney; Lipopolysaccharides; Live | 2000 |
Nitrite/nitrate (NOx) levels and hemodynamics during septic shock.
Topics: Adult; Aged; Endotoxins; Female; Hemodynamics; Humans; Interleukin-8; Male; Middle Aged; Nitrates; N | 2000 |
Nitric oxide indices in human septic shock.
Topics: Adolescent; Adult; Humans; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Severity of Illnes | 2000 |
Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice.
Topics: Animals; Aorta, Thoracic; Bacterial Proteins; Blood Pressure; Body Temperature; Cells, Cultured; Esc | 2001 |
A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the ra
Topics: Animals; Bacillus subtilis; Blood Pressure; Cell Wall; Dose-Response Relationship, Drug; Drug Synerg | 2001 |
Indices of nitric oxide synthesis and outcome in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Critical Care; Cyclic GMP; Female; Humans; Logistic Models; Male; Middle A | 2001 |
Melatonin prevents endotoxin-induced circulatory failure in rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blotting, Western; Chemotaxis, Leukocyte; Endotoxemia; Esche | 2001 |
Recombinant tissue factor pathway inhibitor prevents lipopolysaccharide-induced systemic hypotension in rats by inhibiting excessive production of nitric oxide.
Topics: Animals; Dansyl Compounds; Enzyme Induction; Enzyme Inhibitors; Factor VIIa; Factor Xa Inhibitors; G | 2001 |
A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock.
Topics: Animals; Aorta; Cell Line; Disease Models, Animal; DNA; Drug Interactions; Fibrinolytic Agents; Gene | 2002 |
Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats.
Topics: Acetylcholine; Animals; Blotting, Western; Electrophoresis; Endotoxins; Hemodynamics; Lipopolysaccha | 2002 |
Inducible nitric oxide synthase is not required in the development of endotoxin tolerance in mice.
Topics: Animals; Drug Tolerance; Endotoxins; Female; I-kappa B Proteins; Interleukin-10; Lung; Male; Mice; M | 2002 |
The role of nitric oxide in endotoxic shock: effects of NG-monomethyl-L-arginine.
Topics: Alanine Transaminase; Animals; Arginine; Blood Pressure; Dexamethasone; Lipopolysaccharides; Male; N | 1992 |
A rationale for the prophylactic use of monophosphoryl lipid A in sepsis and septic shock.
Topics: Animals; Cells, Cultured; Female; Interferon-gamma; Lipid A; Lipopolysaccharides; Macrophage Activat | 1992 |