nitrites has been researched along with Schizophrenia in 12 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we sought to verify the cytoprotective role of MGF on cultured rat primary mesencephalic cells exposed to 6-hydroxydopamine (6-OHDA) in vitro, and the MGFs anti-inflammatory potential in mouse model of ketamine-induced schizophrenia in vivo." | 7.78 | Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia. ( Andrade, GM; Carvalho, AC; Magalhães, HI; Moraes, MO; Morais, TC; Nobre-Júnior, HV; Rao, VS; Santos, FA; Trevisan, MT, 2012) |
| "5 improved most of the parameters evaluated in this study without causing motor impairment demonstrating, thus, that possibly when combined with ALA a lower dose of CLZ is required." | 5.42 | Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and neurotrophic mechanisms. ( de Lucena, DF; de Sousa, CN; Gama, CS; Lima, LL; Macêdo, D; Oliveira, Tde Q; Vasconcelos, GS; Vasconcelos, SM; Ximenes, NC, 2015) |
| " Here we sought to verify the cytoprotective role of MGF on cultured rat primary mesencephalic cells exposed to 6-hydroxydopamine (6-OHDA) in vitro, and the MGFs anti-inflammatory potential in mouse model of ketamine-induced schizophrenia in vivo." | 3.78 | Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia. ( Andrade, GM; Carvalho, AC; Magalhães, HI; Moraes, MO; Morais, TC; Nobre-Júnior, HV; Rao, VS; Santos, FA; Trevisan, MT, 2012) |
| "Treatment with risperidone significantly increased the plasma NO(x) levels by 8 weeks (before; 1." | 2.75 | Association between plasma nitric oxide metabolites levels and negative symptoms of schizophrenia: a pilot study. ( Hori, H; Ikenouchi-Sugita, A; Nakamura, J; Nakano, H; Nakano, Y; Ueda, N; Umene-Nakano, W; Yoshimura, R, 2010) |
| "5 improved most of the parameters evaluated in this study without causing motor impairment demonstrating, thus, that possibly when combined with ALA a lower dose of CLZ is required." | 1.42 | Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and neurotrophic mechanisms. ( de Lucena, DF; de Sousa, CN; Gama, CS; Lima, LL; Macêdo, D; Oliveira, Tde Q; Vasconcelos, GS; Vasconcelos, SM; Ximenes, NC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Monte, AS | 2 |
| da Silva, FER | 1 |
| Lima, CNC | 1 |
| Vasconcelos, GS | 2 |
| Gomes, NS | 1 |
| Miyajima, F | 1 |
| Vasconcelos, SMM | 1 |
| Gama, CS | 2 |
| Seeman, MV | 2 |
| de Lucena, DF | 4 |
| Macedo, DS | 3 |
| de Souza, GC | 1 |
| McIntyre, RS | 1 |
| Soczynska, JK | 1 |
| dos Santos, JV | 1 |
| Cordeiro, RC | 1 |
| Ribeiro, BM | 1 |
| Vasconcelos, SM | 3 |
| de Sousa, FC | 2 |
| Carvalho, AF | 3 |
| Ximenes, NC | 1 |
| de Sousa, CN | 1 |
| Oliveira, Tde Q | 1 |
| Lima, LL | 1 |
| Macêdo, D | 2 |
| Célia Moreira Borella, V | 1 |
| Carneiro Cordeiro, R | 1 |
| Vieira dos Santos, J | 1 |
| Romário Matos de Souza, M | 1 |
| Nunes de Sousa Fernandes, E | 1 |
| Santos Monte, A | 1 |
| Maria Mendes Vasconcelos, S | 1 |
| Quinn, JP | 1 |
| Kristofiková, Z | 1 |
| Kozmiková, I | 1 |
| Hovorková, P | 1 |
| Rícný, J | 1 |
| Zach, P | 1 |
| Majer, E | 1 |
| Klaschka, J | 1 |
| Rípová, D | 1 |
| Djordjević, VV | 1 |
| Stojanović, I | 1 |
| Stanković-Ferlez, D | 1 |
| Ristić, T | 1 |
| Lazarević, D | 1 |
| Cosić, V | 1 |
| Djordjević, VB | 1 |
| Nakano, Y | 1 |
| Yoshimura, R | 1 |
| Nakano, H | 1 |
| Ikenouchi-Sugita, A | 1 |
| Hori, H | 1 |
| Umene-Nakano, W | 1 |
| Ueda, N | 1 |
| Nakamura, J | 1 |
| de Araújo, FY | 1 |
| de Oliveira, GV | 1 |
| Gomes, PX | 1 |
| Soares, MA | 1 |
| Silva, MI | 1 |
| de Moraes, MO | 1 |
| de Moraes, ME | 1 |
| Viana, GS | 1 |
| Rao, VS | 1 |
| Carvalho, AC | 1 |
| Trevisan, MT | 1 |
| Andrade, GM | 1 |
| Nobre-Júnior, HV | 1 |
| Moraes, MO | 1 |
| Magalhães, HI | 1 |
| Morais, TC | 1 |
| Santos, FA | 1 |
| WENDKOS, MH | 1 |
| Ramirez, J | 1 |
| Garnica, R | 1 |
| Boll, MC | 1 |
| Montes, S | 1 |
| Rios, C | 1 |
| Srivastava, N | 1 |
| Barthwal, MK | 1 |
| Dalal, PK | 1 |
| Agarwal, AK | 1 |
| Nag, D | 1 |
| Srimal, RC | 1 |
| Seth, PK | 1 |
| Dikshit, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia: A Randomized, Double-blind, Placebo-controlled Trial[NCT03788759] | Phase 2/Phase 3 | 48 participants (Actual) | Interventional | 2019-09-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nitrites and Schizophrenia
| Article | Year |
|---|---|
Association between plasma nitric oxide metabolites levels and negative symptoms of schizophrenia: a pilot study.
Topics: Adult; Antipsychotic Agents; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; | 2010 |
11 other studies available for nitrites and Schizophrenia
| Article | Year |
|---|---|
Sex influences in the preventive effects of N-acetylcysteine in a two-hit animal model of schizophrenia.
Topics: Acetylcysteine; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Corpus Striatum; Fema | 2020 |
Prevention and reversal of ketamine-induced schizophrenia related behavior by minocycline in mice: Possible involvement of antioxidant and nitrergic pathways.
Topics: Animals; Antioxidants; Antipsychotic Agents; Corpus Striatum; Drug Therapy, Combination; Glutathione | 2013 |
Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and neurotrophic mechanisms.
Topics: Analysis of Variance; Animals; Antioxidants; Antipsychotic Agents; Brain; Brain-Derived Neurotrophic | 2015 |
Gender and estrous cycle influences on behavioral and neurochemical alterations in adult rats neonatally administered ketamine.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Endophenotypes | 2016 |
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; F | 2008 |
Plasma nitrite/nitrate concentrations in patients with schizophrenia.
Topics: Adult; Caspase 3; Female; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Schizophrenia; Sex Factors | 2010 |
Inhibition of ketamine-induced hyperlocomotion in mice by the essential oil of Alpinia zerumbet: possible involvement of an antioxidant effect.
Topics: Alpinia; Animals; Antioxidants; Antipsychotic Agents; Glutathione; Haloperidol; Hypnotics and Sedati | 2011 |
Mangiferin ameliorates 6-hydroxydopamine-induced cytotoxicity and oxidative stress in ketamine model of schizophrenia.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Behavior, Animal; Brain; Cell Death; Cel | 2012 |
COMPARATIVE EFFECTIVENESS OF ORGANIC NITRATES: AN OBJECTIVE STUDY IN MAN.
Topics: Coronary Disease; Electrocardiography; Erythrityl Tetranitrate; Humans; Male; Nitrates; Nitrites; Ni | 1963 |
Low concentration of nitrite and nitrate in the cerebrospinal fluid from schizophrenic patients: a pilot study.
Topics: Adult; Brain; Female; Headache; Humans; Male; Nervous System Diseases; Nitrates; Nitric Oxide; Nitri | 2004 |
Nitrite content and antioxidant enzyme levels in the blood of schizophrenia patients.
Topics: Adolescent; Adult; Antioxidants; Blood Platelets; Catalase; Female; Glutathione Peroxidase; Humans; | 2001 |