nitrites and Reperfusion Injury studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

Excerpt	Relevance	Reference
" The aim of the present study was to investigate possible protective effects of L-carnitine (carn) or atorvastatin (ator) on spinal cord ischemia-reperfusion injury (IRI)."	8.02	Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. ( Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA, 2021)
" Both nitrite and carbon monoxide (CO) may protect from this reperfusion injury by limiting mitochondrial free radial production."	7.81	Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. ( Airgood, H; Dezfulian, C; Escobar, D; Gómez, H; Haugaa, H; Holder, A; Kenny, E; Maberry, DR; Ogundele, O; Pinsky, MR; Quintero, AM; Shiva, S; Tønnessen, TI; Zuckerbraun, B, 2015)
"Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema."	7.80	Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014)
"Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia."	7.79	Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013)
"In the present study, we evaluated the effect of neutrophil elastase inhibitor, sivelestat sodium hydrate on ischemia-reperfusion injury in the rat bladder."	7.74	Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder. ( Kono, T; Okada, S; Saito, M, 2008)
"The effect of nitroglycerine on some parameters of the prooxidant-antioxidant balance and functional state of the liver under conditions of ischemia/reperfusion was studied on rabbits."	7.73	Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion. ( Khodosovskii, MN; Zinchuk, VV, 2006)
" Rats that received trapidil before ischemia exhibited decreased MDA levels, and rats that received trapidil after the standard 3 hours of ischemia demonstrated increased tolerance to reperfusion, as reflected in significantly decreased MDA levels."	7.71	Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. ( Bagdatoglu, C; Ozturk, H; Saray, A; Surucu, HS; Tamer, L, 2002)
"Plasma L-arginine is usually deficient immediately after hepatic reperfusion in orthotopic liver transplantation, which may also contribute to the occurrence of either hepatic ischemia-reperfusion injury or pulmonary hypertension."	7.69	Role of exogenous L-arginine in hepatic ischemia-reperfusion injury. ( Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H, 1997)
"Methylene blue (MB) has been used as a vasopressor in sepsis and acute liver failure."	6.70	The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. ( Baumann, J; Bellamy, MC; Gedney, JA; Koelzow, H; Snook, NJ, 2002)
"Treatment of Valsartan attenuated cerebral injury, potentiated the neuroprotective response of iPoCo in normal rats, and also restored the blunted neuroprotective effect of iPoCo in HFD-treated rats along with enhanced Nrf-2 levels."	5.91	Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury. ( Jaggi, AS; Kaur, S; Kumar, K; Singh, N, 2023)
" Dose-response curves to bolus doses of AS, diethylamine NONOate (DEA/NO, both 0."	5.43	The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo. ( Cao, N; Chin, KY; Michel, L; Qin, CX; Ritchie, RH; Woodman, OL, 2016)
"Both erdosteine and ebselen were able to attenuate I/R injury of the intestine via inhibition of lipid peroxidation and protein oxidation, maintenance of antioxidant, and free radical scavenger properties."	5.35	Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. ( Atabek, C; Caliskan, B; Ersoz, N; Guven, A; Kesik, V; Oter, S; Oztas, E; Tunc, T; Uysal, B, 2009)
"Treatment with nitroxyl anion releaser known as Angeli's salt abolished the beneficial effect of dexamethasone in renal ischemia/reperfusion."	5.31	Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl. ( Fujise, Y; Hishida, A; Takahira, R; Yonemura, K, 2001)
" The aim of the present study was to investigate possible protective effects of L-carnitine (carn) or atorvastatin (ator) on spinal cord ischemia-reperfusion injury (IRI)."	4.02	Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. ( Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA, 2021)
" Both nitrite and carbon monoxide (CO) may protect from this reperfusion injury by limiting mitochondrial free radial production."	3.81	Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. ( Airgood, H; Dezfulian, C; Escobar, D; Gómez, H; Haugaa, H; Holder, A; Kenny, E; Maberry, DR; Ogundele, O; Pinsky, MR; Quintero, AM; Shiva, S; Tønnessen, TI; Zuckerbraun, B, 2015)
"Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema."	3.80	Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014)
"Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia."	3.79	Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013)
" Methylene blue exerted neuroprotective effects against the brain damage associated with the ischemia/reperfusion injury and ameliorated the blood-brain barrier disruption by decreasing nitric oxide metabolites."	3.76	Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions. ( Martijn, C; Miclescu, A; Sharma, HS; Wiklund, L, 2010)
"Malondialdehyde (MA) (indicator of LP) in plasma and brain tissue, total nitrite/nitrate (metabolites of nitric oxide) in plasma, nitrite in brain tissue, and SOD in red blood cells were detected and the results were compared before and after VE administration in hyperglycemic rats with cerebral ischemia-reperfusion injury induced by two common carotid artery occlusions."	3.74	The effects of vitamin E on lipid peroxidation, nitric oxide production and superoxide dismutase expression in hyperglycemic rats with cerebral ischemia-reperfusion injury. ( Atükeren, P; Gümüştaş, K; Kaynar, MY; Kemerdere, R; Meta Güzeyli, FM; Sanus, GZ; Tanriverdi, T, 2007)
"In the present study, we evaluated the effect of neutrophil elastase inhibitor, sivelestat sodium hydrate on ischemia-reperfusion injury in the rat bladder."	3.74	Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder. ( Kono, T; Okada, S; Saito, M, 2008)
"Neither allopurinol nor enalapril nor both were protective against ischemia-reperfusion injury in SHR, nor altered glomerular filtration rate and UNOx in a favorable direction."	3.73	Allopurinol and enalapril failed to conserve urinary NOx and sodium in ischemic acute renal failure in spontaneously hypertensive rats. ( Colak, E; Djukanovic, L; Jovovic, D; Mihailovic-Stanojevic, N; Miloradovic, Z; Popovic, T; Radovic, M; Simic-Ogrizovic, S; Tomovic, M, 2006)
"The effect of nitroglycerine on some parameters of the prooxidant-antioxidant balance and functional state of the liver under conditions of ischemia/reperfusion was studied on rabbits."	3.73	Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion. ( Khodosovskii, MN; Zinchuk, VV, 2006)
" ONO-1714 significantly attenuated apoptosis and necrosis, the expression of nitrotyrosine, and the increases of the plasma aspartate aminotransferase, lactate dehydrogenase, and NO(2)- + NO(3)- levels in the reperfusion phase."	3.72	Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714. ( Hirata, K; Isobe, M; Katsuramaki, T; Kimura, H; Kukita, K; Meguro, M; Nagayama, M; Nui, A, 2003)
" Rats that received trapidil before ischemia exhibited decreased MDA levels, and rats that received trapidil after the standard 3 hours of ischemia demonstrated increased tolerance to reperfusion, as reflected in significantly decreased MDA levels."	3.71	Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. ( Bagdatoglu, C; Ozturk, H; Saray, A; Surucu, HS; Tamer, L, 2002)
" The extent of preservation and reperfusion injury were delineated by histologic study and by the measurement of mucosal glutaminase on tissue specimens obtained 20 min after revascularization and 24 hr and 4 weeks postoperatively."	3.69	The effects of administration of nitric oxide inhibitors during small bowel preservation and reperfusion. ( Billiar, TR; Hoffman, RA; Langrehr, JM; Mueller, AR; Nalesnik, M; Nussler, AK; Platz, KP; Schraut, WH, 1994)
"Plasma L-arginine is usually deficient immediately after hepatic reperfusion in orthotopic liver transplantation, which may also contribute to the occurrence of either hepatic ischemia-reperfusion injury or pulmonary hypertension."	3.69	Role of exogenous L-arginine in hepatic ischemia-reperfusion injury. ( Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H, 1997)
"Methylene blue (MB) has been used as a vasopressor in sepsis and acute liver failure."	2.70	The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. ( Baumann, J; Bellamy, MC; Gedney, JA; Koelzow, H; Snook, NJ, 2002)
" A decrease in the production and bioavailability of NO is a hallmark of many major chronic diseases including hypertension, ischaemia-reperfusion injury, atherosclerosis and diabetes."	2.53	Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases. ( Lundberg, JO; Omar, SA; Webb, AJ; Weitzberg, E, 2016)
" This rapid post-ischemic decrease in NO bioavailability appears to be due to decreased synthesis of NO, enhanced inactivation of NO by the overproduction of superoxide or both."	2.45	Hepatocellular protection by nitric oxide or nitrite in ischemia and reperfusion injury. ( Abe, Y; Grisham, MB; Hines, I; Zibari, G, 2009)
"Treatment of Valsartan attenuated cerebral injury, potentiated the neuroprotective response of iPoCo in normal rats, and also restored the blunted neuroprotective effect of iPoCo in HFD-treated rats along with enhanced Nrf-2 levels."	1.91	Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury. ( Jaggi, AS; Kaur, S; Kumar, K; Singh, N, 2023)
" Dose-response curves to bolus doses of AS, diethylamine NONOate (DEA/NO, both 0."	1.43	The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo. ( Cao, N; Chin, KY; Michel, L; Qin, CX; Ritchie, RH; Woodman, OL, 2016)
"Acute kidney injury is usually associated with distant organ dysfunction."	1.43	Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS. ( Fatemikia, H; Karimi, Z; Ketabchi, F; Moosavi, SM, 2016)
" The present study aims to determine the effect of short term (seven-days) administration of high dosage grape seed and skin extract (GSSE 2."	1.42	Protective effect of grape seed and skin extract on cerebral ischemia in rat: implication of transition metals. ( Ezzedine, A; Ferid, L; Meherzia, M; Mohamed, A; Mohamed, E; Pascal, C; Safwen, K; Selima, S, 2015)
" Nitrite administration to CS rats restored nitric oxide bioavailability by enhancing nitrite levels of the muscle, resulting in a reduction of rhabdomyolysis markers such as potassium, lactate dehydrogenase, and creatine phosphokinase."	1.38	Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model. ( Inoue, Y; Kanamoto, I; Kimura, S; Kobayashi, J; Morimoto, Y; Murata, I; Nakano, G; Nozaki, R; Ohtake, K; Ooi, K; Sonoda, K; Uchida, H; Ueda, H, 2012)
"Renal injury induced by brain death is characterized by ischemia and inflammation, and limiting it is a therapeutic goal that could improve outcomes in kidney transplantation."	1.38	Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function. ( Agarwal, A; Bradley, KM; Brandon, A; Bray, MS; Chen, B; Chumley, P; Crossman, DK; Eckhoff, DE; Head, H; Kelpke, SS; Moore, B; Patel, RP; Teng, X; Thompson, JA; Viera, L; Yancey, B, 2012)
"Donation after cardiac death (DCD) donors are vital to maximize the organ donor pool."	1.38	A biphasic response to nitric oxide donation in an ex vivo model of donation after cardiac death renal transplantation. ( Hosgood, SA; Nicholson, ML; Yates, PJ, 2012)
"The neuronal damage following cerebral ischemia is a serious risk to stroke patients."	1.37	Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats. ( Ji, A; Liang, H; Liu, P; Song, S; Wang, Y, 2011)
"The flurbiprofen treatment, 30 min prior to ischemia and 4 h post-reperfusion, afforded significant neuroprotection from ischemic injury as evidenced by reduction in cerebral infarct volume and neurobehavioral deficit."	1.36	Neuroprotective effect of flurbiprofen in focal cerebral ischemia: the possible role of ASIC1a. ( Mishra, V; Raghubir, R; Verma, R, 2010)
"Astaxanthine treatment significantly decreased hepatic conversion of XDH to XO and tissue protein carbonyl levels following IR injury."	1.36	Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion. ( Aslan, M; Cort, A; Curek, GD; Demir, N; Elpek, GO; Ozturk, S; Savas, B; Yucel, G, 2010)
"Both erdosteine and ebselen were able to attenuate I/R injury of the intestine via inhibition of lipid peroxidation and protein oxidation, maintenance of antioxidant, and free radical scavenger properties."	1.35	Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. ( Atabek, C; Caliskan, B; Ersoz, N; Guven, A; Kesik, V; Oter, S; Oztas, E; Tunc, T; Uysal, B, 2009)
"The delaying effects of remote reperfusion injury on the wound-healing process in colonic anastomoses have been previously shown."	1.35	Activated protein C prevents deleterious effects of remote reperfusion injury caused by intestinal ischemia on wound healing in the left colonic anastomoses: an experimental study in the murine model. ( Atalay, AO; Bicakci, T; Erdem, E; Sacar, M; Teke, Z; Yenisey, C, 2008)
"We concluded that curcumin ameliorates cerebral ischemia/reperfusion injury by preventing ONOO(-) mediated blood-brain barrier damage."	1.34	Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. ( Hu, M; Jiang, J; Li, F; Sun, YJ; Wang, W; Zhu, DY, 2007)
"Pulmonary edema was evaluated by Evans blue dye extravasation, as well as lung tissue wet/dry weight ratios."	1.34	Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model. ( Aytekin, FO; Bir, F; Erdem, E; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Yenisey, C, 2007)
"Hypothermia is beneficial in I/R injury, but its effects on systemic oxidative stress have not been elucidated."	1.33	Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injury. ( Eaton, S; Pierro, A; Spitz, L; Stefanutti, G; Vinardi, S, 2005)
"Allopurinol-treated animals exhibited further increased serum alanine aminotransferase(ALT) levels and liver myeloperoxidase(MPO) activities, but further decreased liver adenosine triphosphate(ATP) stores after I/R compared to saline-treated counterparts (830."	1.33	Nitrite-derived nitric oxide by xanthine oxidoreductase protects the liver against ischemia-reperfusion injury. ( Chen, DD; Liu, F; Lu, P; Tian, Y; Wang, CY; Wu, YH; Yao, Z; Zhang, JH, 2005)
" Superoxide decreases the bioavailability of nitric oxide (NO) via its reaction that yields peroxynitrite."	1.33	Endothelial dysfunction in trauma patients: a preliminary communication. ( Lang, JD; Mathru, M, 2005)
" bioavailability and protect against hepatic ischemia-reperfusion (I-R) injury in type 2 diabetes mellitus."	1.33	eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. ( Champion, HC; Dugas, TR; Duranski, MR; Elrod, JW; Greer, JJ; Kevil, CG; Langston, W; Lefer, DJ; Tao, L, 2006)
"Reperfusion injury is a perplexing cause of early graft failure after lung transplantation and today we know that reperfusion may be more harmful to tissues than the preceding ischemia."	1.33	Beneficial effects of supplemental nitric oxide donor given during reperfusion period in reperfusion-induced lung injury. ( Demirel, R; Dilek, FH; Esme, H; Fidan, H; Solak, O; Unlu, M, 2006)
"Melatonin treatment increased survival and reduced hyperactivity linked to neurodegeneration induced by cerebral ischemia and reperfusion."	1.31	Protective effects of melatonin in ischemic brain injury. ( Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I, 2000)
"M40401 treatment markedly reduced the intensity and degree of P-selectin and ICAM-1 in tissue sections from SAO-shocked rats."	1.31	Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion. ( Aston, K; Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D, 2001)
"Treatment with nitroxyl anion releaser known as Angeli's salt abolished the beneficial effect of dexamethasone in renal ischemia/reperfusion."	1.31	Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl. ( Fujise, Y; Hishida, A; Takahira, R; Yonemura, K, 2001)
" L-Arginine was infused at a dosage of 500 mg/kg body weight into the donor pigs (30 min before liver explantation) and also into the recipients (over a period of 3 hr from the beginning of the reperfusion period)."	1.30	Improvement of cardiac output and liver blood flow and reduction of pulmonary vascular resistance by intravenous infusion of L-arginine during the early reperfusion period in pig liver transplantation. ( Benditte, H; Grünberger, T; Längle, F; Mittlböck, M; Mühlbacher, F; Roth, E; Schindl, M; Soliman, T; Steininger, R; Waldmann, E; Windberger, U, 1997)

Research

Studies (173)

Authors

Clinical Trials (15)

Trial Overview

Trial Outcomes

Number of Participants With Delayed Recovery of Liver Function

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (10.40)	18.2507
2000's	91 (52.60)	29.6817
2010's	56 (32.37)	24.3611
2020's	8 (4.62)	2.80

Authors	Studies
Nahavandi, S	1
Ahmadi, S	1
Sobhani, SA	1
Abbasi, T	1
Dehghani, A	1
Olejnik, A	1
Banaszkiewicz, M	1
Krzywonos-Zawadzka, A	1
Bil-Lula, I	1
Alabi, B	1
Iwalewa, O	1
Omobowale, T	1
Adedapo, A	1
Hammed, O	1
Ajike, R	1
Afolabi, O	1
Abdi, A	1
Kadkhodaee, M	2
Seifi, B	1
Kianian, F	1
Lorian, K	1
Shams, S	2
Bakhshi, E	1
Ashabi, G	1
Ranjbaran, M	1
Kaur, S	1
Kumar, K	1
Singh, N	1
Jaggi, AS	1
Kumar, A	1
Noda, K	1
Philips, B	1
Velayutham, M	1
Stolz, DB	2
Gladwin, MT	9
Shiva, S	11
D'Cunha, J	1
Halim, AA	1
Alsayed, B	1
Embarak, S	1
Yaseen, T	1
Dabbous, S	1
Fontaine, O	1
Dueluzeau, R	1
Raibaud, P	1
Chabanet, C	1
Popoff, MR	1
Badoual, J	1
Gabilan, JC	1
Andremont, A	1
Gómez, L	1
Andrés, S	1
Sánchez, J	1
Alonso, JM	1
Rey, J	1
López, F	1
Jiménez, A	1
Yan, Z	1
Zhou, L	1
Zhao, Y	3
Wang, J	6
Huang, L	3
Hu, K	1
Liu, H	4
Wang, H	3
Guo, Z	1
Song, Y	1
Huang, H	5
Yang, R	1
Owen, TW	1
Al-Kaysi, RO	1
Bardeen, CJ	1
Cheng, Q	1
Wu, S	1
Cheng, T	1
Zhou, X	1
Wang, B	4
Zhang, Q	4
Wu, X	2
Yao, Y	3
Ochiai, T	1
Ishiguro, H	2
Nakano, R	2
Kubota, Y	2
Hara, M	1
Sunada, K	1
Hashimoto, K	1
Kajioka, J	1
Fujishima, A	1
Jiao, J	3
Gai, QY	3
Wang, W	3
Zang, YP	2
Niu, LL	2
Fu, YJ	3
Wang, X	7
Yao, LP	1
Qin, QP	1
Wang, ZY	1
Liu, J	5
Aleksic Sabo, V	1
Knezevic, P	1
Borges-Argáez, R	1
Chan-Balan, R	1
Cetina-Montejo, L	1
Ayora-Talavera, G	1
Sansores-Peraza, P	1
Gómez-Carballo, J	1
Cáceres-Farfán, M	1
Jang, J	1
Akin, D	1
Bashir, R	1
Yu, Z	1
Zhu, J	2
Jiang, H	1
He, C	2
Xiao, Z	1
Xu, J	2
Sun, Q	1
Han, D	1
Lei, H	1
Zhao, K	2
Zhu, L	1
Li, X	4
Fu, H	2
Wilson, BK	1
Step, DL	1
Maxwell, CL	1
Gifford, CA	1
Richards, CJ	1
Krehbiel, CR	1
Warner, JM	1
Doerr, AJ	1
Erickson, GE	1
Guretzky, JA	1
Rasby, RJ	1
Watson, AK	1
Klopfenstein, TJ	1
Sun, Y	4
Liu, Z	3
Pham, TD	1
Lee, BK	1
Yang, FC	1
Wu, KH	1
Lin, WP	1
Hu, MK	1
Lin, L	3
Shao, J	1
Sun, M	1
Xu, G	1
Zhang, X	7
Xu, N	1
Wang, R	1
Liu, S	1
He, H	1
Dong, X	2
Yang, M	2
Yang, Q	1
Duan, S	1
Yu, Y	2
Han, J	2
Zhang, C	3
Chen, L	2
Yang, X	1
Li, W	3
Wang, T	2
Campbell, DA	1
Gao, K	1
Zager, RA	1
Johnson, ACM	1
Guillem, A	1
Keyser, J	1
Singh, B	1
Steubl, D	1
Schneider, MP	1
Meiselbach, H	1
Nadal, J	1
Schmid, MC	1
Saritas, T	1
Krane, V	1
Sommerer, C	1
Baid-Agrawal, S	1
Voelkl, J	1
Kotsis, F	1
Köttgen, A	1
Eckardt, KU	1
Scherberich, JE	1
Li, H	5
Yao, L	2
Sun, L	3
Zhu, Z	1
Naren, N	1
Zhang, XX	2
Gentile, GL	1
Rupert, AS	1
Carrasco, LI	1
Garcia, EM	1
Kumar, NG	1
Walsh, SW	1
Jefferson, KK	1
Guest, RL	1
Samé Guerra, D	1
Wissler, M	1
Grimm, J	1
Silhavy, TJ	1
Lee, JH	2
Yoo, JS	1
Kim, Y	1
Kim, JS	2
Lee, EJ	2
Roe, JH	1
Delorme, M	1
Bouchard, PA	1
Simon, M	1
Simard, S	1
Lellouche, F	1
D'Urzo, KA	1
Mok, F	1
D'Urzo, AD	1
Koneru, B	1
Lopez, G	1
Farooqi, A	1
Conkrite, KL	1
Nguyen, TH	1
Macha, SJ	1
Modi, A	1
Rokita, JL	1
Urias, E	1
Hindle, A	1
Davidson, H	1
Mccoy, K	1
Nance, J	1
Yazdani, V	1
Irwin, MS	1
Yang, S	1
Wheeler, DA	1
Maris, JM	1
Diskin, SJ	1
Reynolds, CP	1
Abhilash, L	1
Kalliyil, A	1
Sheeba, V	1
Hartley, AM	2
Meunier, B	2
Pinotsis, N	1
Maréchal, A	2
Xu, JY	1
Genko, N	1
Haraux, F	1
Rich, PR	1
Kamalanathan, M	1
Doyle, SM	1
Xu, C	1
Achberger, AM	1
Wade, TL	1
Schwehr, K	1
Santschi, PH	1
Sylvan, JB	1
Quigg, A	1
Leong, W	1
Xu, W	2
Gao, S	1
Zhai, X	1
Wang, C	2
Gilson, E	1
Ye, J	1
Lu, Y	1
Yan, R	1
Zhang, Y	6
Hu, Z	1
You, Q	1
Cai, Q	1
Yang, D	1
Gu, S	1
Dai, H	1
Zhao, X	1
Gui, C	1
Gui, J	1
Wu, PK	1
Hong, SK	1
Starenki, D	1
Oshima, K	1
Shao, H	1
Gestwicki, JE	1
Tsai, S	1
Park, JI	1
Wang, Y	10
Zhao, R	1
Gu, Z	1
Dong, C	2
Guo, G	1
Li, L	4
Barrett, HE	1
Meester, EJ	1
van Gaalen, K	1
van der Heiden, K	1
Krenning, BJ	1
Beekman, FJ	1
de Blois, E	1
de Swart, J	1
Verhagen, HJ	1
Maina, T	1
Nock, BA	1
Norenberg, JP	1
de Jong, M	1
Gijsen, FJH	1
Bernsen, MR	1
Martínez-Milla, J	1
Galán-Arriola, C	1
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Cobiella, J	1
Pérez-Camargo, D	1
Bautista-Hernández, V	1
Rigol, M	1
Solanes, N	1
Villena-Gutierrez, R	1
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Mateo, J	1
Vilchez-Tschischke, JP	1
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Schweitzer, DH	1
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Geusens, PP	1
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Zhu, X	1
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Yang, G	2
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Trial	Phase	Enrollment	Study Type	Start Date	Status
The Effect of Remote Ischemic Preconditioning on the Postoperative Liver Function in Living Donor Hepatectomy: a Randomized Clinical Trial[NCT03386435]		160 participants (Actual)	Interventional	2016-08-22	Completed
Pulmonary Remote Preconditioning by Ischemia-reperfusion in Lung Lobectomy. A Study on the Prevention of Oxidative Stress[NCT02734654]		53 participants (Actual)	Interventional	2007-11-30	Completed
The Effects of Chronic Dietary Nitrate Supplementation on Constant Work Rate Exercise in High Functioning Middle Aged and Older Adults[NCT03371966]		29 participants (Actual)	Interventional	2017-12-13	Completed
Production of Fortified Biscuit With Chickpea and Crushed Peanut and Evaluating Its Effectiveness in Terms of Its Acceptability and Cognitive Performance: a Pilot Study Among Egyptian Primary School-aged Children[NCT05281146]		80 participants (Actual)	Interventional	2018-11-26	Completed
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Meat Intake - Pilot Study of the Nitrate INFORMER Studies; Nitrate INFORMER Studies: Is Nitrosamine FORMation dEpenent on souRce[NCT05045807]		6 participants (Actual)	Interventional	2021-10-11	Completed
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Meat Intake - Meat Study of the Nitrate INFORMER Studies; Nitrate INFORMER Studies: Is Nitrosamine FORMation dEpenent on souRce[NCT05075720]		25 participants (Actual)	Interventional	2022-09-27	Completed
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Vegetable Intake[NCT05886023]		25 participants (Anticipated)	Interventional	2023-06-26	Recruiting
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Water Intake[NCT05710341]		25 participants (Actual)	Interventional	2023-02-08	Completed
A Safety and Efficacy Evaluation of Sodium Nitrite Injection for the Prevention of Ischemia-Reperfusion Injury Associated With Acute Myocardial Infarction.[NCT00924118]	Phase 2	30 participants (Actual)	Interventional	2009-07-31	Completed
Nitrative Stress in Heart Failure: The Cleveland Heart and Metabolic Prevention Study (CHAMPS)[NCT03012022]		1,208 participants (Actual)	Observational	2010-11-30	Active, not recruiting
NITRATE-OCT-CIN Trial: A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina (Sub-study of the NITRATE-OCT Trial)[NCT05544981]		300 participants (Actual)	Interventional	2016-01-02	Completed
Dietary Nitrate Supplementation and Thermoregulation During Exercise[NCT03506646]		10 participants (Anticipated)	Interventional	2018-09-05	Active, not recruiting
The Acute Effect of Beetroot Juice on Circulating Nitrate and Nitrite Levels and Blood Pressure in Normotensives and Hypertensives[NCT01236872]		15 participants (Actual)	Interventional	2009-12-31	Completed
Acute Dietary Nitrate Supplementation to Improve Performance in Endurance Trained Athletes[NCT01384968]		20 participants (Actual)	Interventional	2011-07-31	Completed
Shuxuening Injection for the Prevention of Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage -- A Randomized, Double-blind, Placebo-parallel Controlled Clinical Trial[NCT06138353]	Phase 2/Phase 3	50 participants (Anticipated)	Interventional	2023-11-13	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

The incidence of delayed recovery of hepatic function (DRHF) were used as surrogate parameters indicating the possible benefits of RIPC. DRHF was defined based on a proposal by the International Study Group of Liver Surgery, as follows: an impaired ability of the liver to maintain its synthetic, excretory, and detoxifying functions, which are characterized by an increased PT INR and concomitant hyperbilirubinemia (considering the normal limits of the local laboratory) on or after postoperative day 5. The normal upper limits of PT and bilirubin in our institutional laboratory were 1.30 INR and 1.2 mg/dL, respectively. If either the PT INR or serum bilirubin concentration was preoperatively elevated, DRHF was defined by an increasing PT INR and increasing serum bilirubin concentration on or after postoperative day 5 (compared with the values of the previous day). (NCT03386435)
Timeframe: postoperative 7 days

Postopera The Maximal Aspartate Aminotransferase Level Within 7 Postoperative Days

Intervention	Participants (Count of Participants)
RIPC	5
Control	0

The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal aspartate aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy. (NCT03386435)
Timeframe: within 7 days after operation

Postoperative Liver Regeneration

Intervention	IU/L (Mean)
RIPC	145
Control	152

The postoperative liver regeneration index (LRI) at postoperative 1 month ) was used as surrogate parameters indicating the possible benefits of RIPC. The LRI was defined as [(VLR - VFLR)/VFLR)] × 100, where VLR is the volume of the liver remnant and VFLR is the volume of the future liver remnant. Liver volume was calculated by CT volumetry using 3-mm-thick dynamic CT images. The graft weight was subtracted from the total liver volume to define the future liver remnant. (NCT03386435)
Timeframe: 1 month

The Maximal Alanine Aminotransferase Level Within 7 Postoperative Days

Intervention	percentage of liver volume (Mean)
RIPC	83.3
Control	94.9

The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal alanine aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy (NCT03386435)
Timeframe: within 7 days after operation

Left Ventricular Infarct Size

Intervention	IU/L (Mean)
RIPC	148
Control	152

Left ventricular infarct size by Magnetic Resonance Imaging (MRI). Calculated percentage of the left ventricular mass by MRI that has undergone infarction. (NCT00924118)
Timeframe: 4-5 days following enrollment

Article	Year
The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1 Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P	2016
Nitrite in organ protection. British journal of pharmacology, 2014, Volume: 171, Issue:1 Topics: Animals; Cytoprotection; Humans; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitrites; Pr	2014
Novel approaches and opportunities for cardioprotective signaling through 3',5'-cyclic guanosine monophosphate manipulation. Journal of cardiovascular pharmacology and therapeutics, 2014, Volume: 19, Issue:3 Topics: Cyclic GMP; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Humans; Natriuretic Peptides; Nitrates;	2014
Nitrite Confers Preconditioning and Cytoprotection After Ischemia/Reperfusion Injury Through the Modulation of Mitochondrial Function. Antioxidants & redox signaling, 2015, Aug-01, Volume: 23, Issue:4 Topics: Animals; Apoptosis; Cytoprotection; Humans; Ischemic Preconditioning; Mitochondria; Nitrites; Reacti	2015
Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases. Journal of internal medicine, 2016, Volume: 279, Issue:4 Topics: Animals; Biological Availability; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Di	2016
Hepatocellular protection by nitric oxide or nitrite in ischemia and reperfusion injury. Archives of biochemistry and biophysics, 2009, Apr-15, Volume: 484, Issue:2 Topics: Animals; Cytokines; Hepatocytes; Humans; Ischemia; Liver Circulation; Liver Transplantation; Nitric	2009
Dietary sources of nitrite as a modulator of ischemia/reperfusion injury. Kidney international, 2009, Volume: 75, Issue:11 Topics: Cytoprotection; Diet Therapy; Homeostasis; Humans; Nitrites; Reperfusion Injury	2009
Nitrite as regulator of hypoxic signaling in mammalian physiology. Medicinal research reviews, 2009, Volume: 29, Issue:5 Topics: Animals; Humans; Hypoxia; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidatio	2009
Effects of nitrite on modulating ROS generation following ischemia and reperfusion. Advanced drug delivery reviews, 2009, Apr-28, Volume: 61, Issue:4 Topics: Animals; Humans; Ischemia; Nitric Oxide Donors; Nitrites; Reactive Oxygen Species; Reperfusion Injur	2009
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
NO-synthase independent NO generation in mammals. Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1 Topics: Animals; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury; Va	2010
Nitrite as a mediator of ischemic preconditioning and cytoprotection. Nitric oxide : biology and chemistry, 2011, Aug-01, Volume: 25, Issue:2 Topics: Animals; Cytochromes c; Cytoprotection; Glutathione; Humans; Ischemic Preconditioning; Mice; Mitocho	2011
Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy. Free radical biology & medicine, 2011, Aug-15, Volume: 51, Issue:4 Topics: Animals; Blood Flow Velocity; Clinical Trials as Topic; Humans; Hypoxia; Molecular Targeted Therapy;	2011
Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics. Cardiovascular research, 2007, Jul-15, Volume: 75, Issue:2 Topics: Animals; Anions; Cytoprotection; Humans; Models, Animal; Muscle Cells; Nitric Oxide; Nitrites; Reper	2007
Non-enzymatic nitric oxide synthesis in biological systems. Biochimica et biophysica acta, 1999, May-05, Volume: 1411, Issue:2-3 Topics: Animals; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heart; Hemeproteins; Hydrogen-Ion	1999
Nitric oxide synthase-independent generation of nitric oxide in muscle ischemia--reperfusion injury. Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:6 Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Mice; Muscle, Skeletal; Myocardium; Ni	2000

Article	Year
The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1 Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P	2016
Remote ischaemic preconditioning suppresses endogenous plasma nitrite during ischaemia-reperfusion: a randomized controlled crossover pilot study. British journal of clinical pharmacology, 2017, Volume: 83, Issue:7 Topics: Adult; Cross-Over Studies; Healthy Volunteers; Humans; Ischemia; Ischemic Preconditioning; Male; Nit	2017
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Adolescent; Adult; Beta vulgaris; Blood Pressure; Cross-Over Studies; Diet; Endothelium, Vascular; H	2008
Increased nitric oxide production in the liver in the perioperative period of partial hepatectomy with Pringle's maneuver. Journal of hepatology, 1998, Volume: 28, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Cytokines; Endotoxins; Enzyme Induction	1998
The effect of methylene blue on the hemodynamic changes during ischemia reperfusion injury in orthotopic liver transplantation. Anesthesia and analgesia, 2002, Volume: 94, Issue:4 Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Cyclic GMP; Enzyme Inhibitors; Female; Guan	2002

Article	Year
A high dose of estrogen can improve renal ischemia-reperfusion-induced pulmonary injury in ovariectomized female rats. Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:12 Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Estradiol; Female; Injections, Intramuscular	2021
The Klotho protein supports redox balance and metabolic functions of cardiomyocytes during ischemia/reperfusion injury. Cardiology journal, 2022, Volume: 29, Issue:5 Topics: Deoxyglucose; Glucose; Humans; Hydrogen Peroxide; Ischemia; Lactates; Myocytes, Cardiac; NADP; NADPH	2022
Cysteamine Attenuate Intestinal Reperfusion Injury Induced by Occlusion of Mesenteric Artery by Enhancing Intracellular Thiol Activities. Drug research, 2023, Volume: 73, Issue:3 Topics: Animals; Cysteamine; Hydrogen Peroxide; Intestines; Mesenteric Arteries; Nitrites; Rats; Rats, Wista	2023
Point-of-care salivary oxidative and renal functional markers to assess kidney function in reperfusion-induced acute kidney injury in male rats. Hormone molecular biology and clinical investigation, 2023, Sep-01, Volume: 44, Issue:3 Topics: Acute Kidney Injury; Animals; bcl-2-Associated X Protein; Corticosterone; Humans; Kidney; Male; Nitr	2023
Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury. Current neurovascular research, 2023, Volume: 20, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain Ischemia;	2023
Nitrite attenuates mitochondrial impairment and vascular permeability induced by ischemia-reperfusion injury in the lung. American journal of physiology. Lung cellular and molecular physiology, 2020, 04-01, Volume: 318, Issue:4 Topics: A549 Cells; Animals; Capillary Permeability; Cell Line, Tumor; Cytoprotection; Electron Transport Co	2020
Effects of renal ischemia injury on brain in diabetic and non-diabetic rats: Role of angiotensin II type 2 receptor and angiotensin-converting enzyme 2. European journal of pharmacology, 2020, Sep-05, Volume: 882 Topics: Angiotensin-Converting Enzyme 2; Animals; Brain; Diabetes Mellitus, Experimental; Diminazene; Hyperg	2020
Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. Journal of immunoassay & immunochemistry, 2021, Nov-02, Volume: 42, Issue:6 Topics: Advanced Oxidation Protein Products; Animals; Atorvastatin; bcl-2-Associated X Protein; Carnitine; C	2021
Nitrite enhances liver graft protection against cold ischemia reperfusion injury through a NOS independent pathway. The Libyan journal of medicine, 2017, Volume: 12, Issue:1 Topics: Animals; Cryopreservation; Lipid Peroxidation; Liver; NG-Nitroarginine Methyl Ester; Nitric Oxide Sy	2017
Protective effect of glutamine on the main and adjacent organs damaged by ischemia-reperfusion in rats. Protoplasma, 2017, Volume: 254, Issue:6 Topics: Activating Transcription Factor 6; Alanine Transaminase; Animals; Aspartate Aminotransferases; Drug	2017
Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney. Journal of the American College of Cardiology, 2017, Oct-24, Volume: 70, Issue:17 Topics: Aminobutyrates; Angiotensin II; Animals; Biphenyl Compounds; Bisoprolol; Blood Pressure; Drug Combin	2017
Differential mitochondrial dinitrosyliron complex formation by nitrite and nitric oxide. Redox biology, 2018, Volume: 15 Topics: Aconitate Hydratase; Animals; Antioxidants; Cytoprotection; Hypoxia; Iron; Kidney; Liver; Mice; Mito	2018
Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats. Journal of ethnopharmacology, 2018, Sep-15, Volume: 223 Topics: Animals; Antioxidants; Brain; Catalase; Cell Survival; Cytokines; Glutathione; Lamiaceae; Male; Meth	2018
[THE ROLE OF THE BLOOD OXYGEN IN PROTECTIVE MECHANISM OF ISCHEMIC PRECONDITIONING DURING HEPATIC ISCHEMIA-REPERFUSION]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:8 Topics: Animals; Antioxidants; Ischemic Preconditioning; Lipid Peroxidation; Liver; Male; Nitrates; Nitrites	2016
Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepatic steatosis or steatohepatitis. Acta cirurgica brasileira, 2018, Volume: 33, Issue:9 Topics: Animals; Disease Models, Animal; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Nitrites; Non-a	2018
Does the method of expression of venous blood affect ischaemia/reperfusion damage in tourniquet use? An experimental study on rabbits. Injury, 2013, Volume: 44, Issue:11 Topics: Acidosis; Animals; Biomarkers; Ischemia; Malondialdehyde; Muscle, Skeletal; Nitrates; Nitrites; Orth	2013
Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. PloS one, 2013, Volume: 8, Issue:9 Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Calcium; Dose-Response R	2013
Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. Life sciences, 2014, Apr-01, Volume: 100, Issue:2 Topics: Animals; Antioxidants; Apoptosis; Aquaporin 4; Blotting, Western; Brain Edema; Brain Ischemia; Calci	2014
Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion. PloS one, 2014, Volume: 9, Issue:7 Topics: Animals; Apoptosis; I-kappa B Proteins; Inflammation; Interleukin-6; Ischemia; Jejunum; JNK Mitogen-	2014
Conventional, but not remote ischemic preconditioning, reduces iNOS transcription in liver ischemia/reperfusion. World journal of gastroenterology, 2014, Jul-28, Volume: 20, Issue:28 Topics: Animals; Disease Models, Animal; Down-Regulation; Hindlimb; Inflammation Mediators; Ischemic Precond	2014
Protective effect of grape seed and skin extract on cerebral ischemia in rat: implication of transition metals. International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:3 Topics: Animals; Antioxidants; Brain; Brain Ischemia; Calcium; Calpain; Cerebral Infarction; Female; Malondi	2015
Interaction between NMDA glutamatergic and nitrergic enteric pathways during in vitro ischemia and reperfusion. European journal of pharmacology, 2015, Mar-05, Volume: 750 Topics: Animals; Enzyme Inhibitors; Glutamic Acid; Guinea Pigs; Ileum; Male; Myenteric Plexus; N-Methylaspar	2015
Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. Critical care (London, England), 2015, Apr-22, Volume: 19 Topics: Administration, Inhalation; Animals; Carbon Monoxide; Microdialysis; Mitochondria; Nitrites; Oxygen	2015
Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion. European journal of pharmacology, 2015, Sep-05, Volume: 762 Topics: Active Transport, Cell Nucleus; Amides; Animals; Apoptosis; Cell Nucleus; Chymases; Cytokines; Disea	2015
Oxidative lung injury correlates with one-lung ventilation time during pulmonary lobectomy: a study of exhaled breath condensate and blood. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2015, Volume: 48, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Breath Tests; Dinoprost; Female; Humans; Hydrogen Peroxi	2015
The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free radical biology & medicine, 2015, Volume: 89 Topics: Animals; Cells, Cultured; Cytoprotection; Glutathione; Hypoxia; Iron; Lipid Peroxidation; Liver; Mit	2015
The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo. Pharmacological research, 2016, Volume: 104 Topics: Animals; Cardiotonic Agents; Dobutamine; Heart; Hemodynamics; Male; Myocardial Contraction; Nitric O	2016
Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS. Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:5 Topics: Acute Kidney Injury; alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Enzyme Inhibit	2016
Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration. American journal of physiology. Renal physiology, 2016, 08-01, Volume: 311, Issue:2 Topics: Animals; Creatine; Cytokines; Enzyme Inhibitors; Interleukin-10; Kidney; Kidney Diseases; Male; NG-N	2016
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis. Nature chemical biology, 2008, Volume: 4, Issue:7 Topics: Adult; Allopurinol; Animals; Blood Pressure; Disease Models, Animal; Female; Homeostasis; Humans; Li	2008
Activated protein C attenuates intestinal mucosal injury after mesenteric ischemia/reperfusion. The Journal of surgical research, 2008, Volume: 149, Issue:2 Topics: Animals; Anticoagulants; Edema; Fibrin Fibrinogen Degradation Products; Glutathione; Glutathione Red	2008
Effects of tempol, a membrane-permeable radical scavenger, on local and remote organ injuries caused by intestinal ischemia/reperfusion in rats. The Journal of surgical research, 2008, Volume: 149, Issue:2 Topics: Animals; Capillary Permeability; Cyclic N-Oxides; Edema; Free Radical Scavengers; Glutathione; Intes	2008
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat. Behavioural brain research, 2008, Nov-21, Volume: 193, Issue:2 Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea	2008
Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America, 2008, Aug-12, Volume: 105, Issue:32 Topics: Animals; Biological Transport; Cytoprotection; Liver; Mice; Mice, Transgenic; Myocardium; Nitrates;	2008
Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion. Gastroenterology, 2008, Volume: 135, Issue:4 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Energy Metabolism; Enzymes; Liver; Male;	2008
Polymerized placenta hemoglobin attenuates ischemia/reperfusion injury and restores the nitroso-redox balance in isolated rat heart. Free radical biology & medicine, 2009, Feb-01, Volume: 46, Issue:3 Topics: Animals; Apoptosis; Female; Heart Function Tests; Heart Transplantation; Hemoglobins; Humans; Hydrog	2009
Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Amidines; Animals; Benzylamines; E-Selectin; Enzyme Inhibitors; Epithelial Cells; Hindlimb; Inflamma	2009
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury. European journal of pharmacology, 2009, May-21, Volume: 610, Issue:1-3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells,	2009
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia. Experimental neurology, 2009, Volume: 217, Issue:1 Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Lin	2009
Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response. Free radical biology & medicine, 2009, Sep-01, Volume: 47, Issue:5 Topics: Animal Structures; Animals; Cytoprotection; Diet; Gastric Mucosa; Gene Expression Profiling; Heart;	2009
Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. The Journal of surgical research, 2009, Volume: 155, Issue:2 Topics: Animals; Antioxidants; Azoles; Biomarkers; Glutathione Peroxidase; Intestinal Mucosa; Intestine, Sma	2009
Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase. Journal of dermatological science, 2009, Volume: 55, Issue:2 Topics: Biomarkers; Cell Hypoxia; Cell Line; Cell Survival; Glucose; Glutathione; Glutathione Disulfide; Hum	2009
Resveratrol, a natural antioxidant, attenuates intestinal ischemia/reperfusion injury in rats. The Tohoku journal of experimental medicine, 2009, Volume: 218, Issue:3 Topics: Animals; Antioxidants; Bacterial Translocation; Female; Free Radical Scavengers; Intestinal Mucosa;	2009
Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. Nitric oxide : biology and chemistry, 2010, Feb-15, Volume: 22, Issue:2 Topics: Animals; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide	2010
Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion. Toxicology, 2010, Jan-12, Volume: 267, Issue:1-3 Topics: Alanine Transaminase; Animals; Antioxidants; Disease Models, Animal; Glutathione; Liver; Male; Nitra	2010
A potential protective effect of alpha-tocopherol on vascular complication in spinal cord reperfusion injury in rats. Journal of biomedical science, 2010, Jul-07, Volume: 17 Topics: alpha-Tocopherol; Analysis of Variance; Animals; Antioxidants; Dinoprostone; Injections, Intramuscul	2010
Beneficial effects of physical training on the cardio-inflammatory disorder induced by lung ischemia/reperfusion in rats. Inflammation, 2011, Volume: 34, Issue:5 Topics: Animals; Interleukin-6; Lung Injury; Male; Mesenteric Arteries; NADPH Oxidases; Nitrates; Nitrites;	2011
Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions. Critical care medicine, 2010, Volume: 38, Issue:11 Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Ischemia; Cardiopulmonary Resuscitation; Cere	2010
Neuroprotective effect of flurbiprofen in focal cerebral ischemia: the possible role of ASIC1a. Neuropharmacology, 2010, Volume: 59, Issue:7-8 Topics: Acid Sensing Ion Channels; Animals; Brain; Brain Infarction; Calcium; Flurbiprofen; Ischemic Attack,	2010
Effects of long term nitrite therapy on functional recovery in experimental ischemia model. Biochemical and biophysical research communications, 2010, Dec-03, Volume: 403, Issue:1 Topics: Animals; Brain Ischemia; Caspases; Cytokines; Disease Models, Animal; Female; Humans; Neovasculariza	2010
Effect of acute alloxan diabetes on ischemic and reperfusion arrhythmias in rats with different activity of nitric oxide system. Bulletin of experimental biology and medicine, 2011, Volume: 150, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Blotting, Western; Diabetes Mellitus, Experimental; Heme Oxygenase (D	2011
Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jul-15, Volume: 18, Issue:10 Topics: Alkaloids; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Leonurus; Male; M	2011
Spatial and temporal patterns of oxidative stress in the brain of gerbils submitted to different duration of global cerebral ischemia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:6 Topics: Animals; Brain; Brain Ischemia; Gerbillinae; Glutathione; Lipid Peroxidation; Male; Nitric Oxide; Ni	2011
Effects of oral administration of (L)-arginine, (L)-NAME and allopurinol on intestinal ischemia/reperfusion injury in rats. Life sciences, 2011, Jun-06, Volume: 88, Issue:23-24 Topics: Administration, Oral; Allopurinol; Animals; Arginine; Catalase; Intestines; Male; NG-Nitroarginine M	2011
A biphasic response to nitric oxide donation in an ex vivo model of donation after cardiac death renal transplantation. The Journal of surgical research, 2012, Jun-15, Volume: 175, Issue:2 Topics: Animals; Creatinine; Death; Kidney; Kidney Transplantation; Models, Animal; Nitrates; Nitric Oxide D	2012
Atorvastatin protects against ischemia-reperfusion injury in fructose-induced insulin resistant rats. Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:4 Topics: Animals; Atorvastatin; Endothelium, Vascular; Fructose; Heptanoic Acids; Hydroxymethylglutaryl-CoA R	2011
Interplay of endothelial and inducible nitric oxide synthases modulates the vascular response to ischaemia-reperfusion in the rabbit lung. Acta physiologica (Oxford, England), 2012, Volume: 204, Issue:3 Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Lung; NADPH Oxidases; Nitrates; Nitric Oxide; Ni	2012
Nitrite attenuates ischemia-reperfusion-induced microcirculatory alterations and mitochondrial dysfunction in the microvasculature of skeletal muscle. Plastic and reconstructive surgery, 2011, Volume: 128, Issue:4 Topics: Analysis of Variance; Animals; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Dr	2011
San-Huang-Xie-Xin-Tang protects cardiomyocytes against hypoxia/reoxygenation injury via inhibition of oxidative stress-induced apoptosis. Journal of natural medicines, 2012, Volume: 66, Issue:2 Topics: Animals; Apoptosis; Blotting, Western; Cell Hypoxia; Cell Line; Cell Survival; Drugs, Chinese Herbal	2012
[Study of changes in the parametres of oxidative stress, anti-oxidative defence and endothelial dysfunction in acute ischemia-reperfusion of the lower extremities in humans]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:4 Topics: Acute Disease; Aged; Alanine Transaminase; Antioxidants; Arterial Occlusive Diseases; Aspartate Amin	2011
N-acetyl cysteine improves glycogenesis after segmental liver ischemia and reperfusion injury in pigs. Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:2 Topics: Acetylcysteine; Adenosine Triphosphate; Analysis of Variance; Animals; Apoptosis; Aspartate Aminotra	2012
Protective effect of hydroalcoholic extract of Mimusops elengi Linn. flowers against middle cerebral artery occlusion induced brain injury in rats. Journal of ethnopharmacology, 2012, Mar-27, Volume: 140, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Blood-Brain Barrier; Brain Edema;	2012
Cysteinyl leukotriene receptor antagonism alleviates renal injury induced by ischemia-reperfusion in rats. The Journal of surgical research, 2012, Volume: 178, Issue:1 Topics: Animals; Disease Models, Animal; Indoles; Intercellular Adhesion Molecule-1; Kidney Diseases; Leukot	2012
Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function. Kidney international, 2012, Volume: 82, Issue:3 Topics: Allopurinol; Animals; Benzoates; Brain Death; Gene Expression; Hemodynamics; Imidazoles; Inflammatio	2012
Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model. The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:6 Topics: Analysis of Variance; Animals; Blood Pressure Determination; Crush Syndrome; Disease Models, Animal;	2012
[Effect of sodium nitroprusside on hemoglobin oxygen binding properties of the blood during hepatic ischemia-reperfusion in rabbits]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:5 Topics: Acid-Base Equilibrium; Animals; Blood Pressure; Hemoglobins; Hydrogen-Ion Concentration; Injections,	2012
Nitrite reduces acute lung injury and improves survival in a rat lung transplantation model. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2012, Volume: 12, Issue:11 Topics: Acute Lung Injury; Animals; Disease Models, Animal; Graft Rejection; Graft Survival; Lung Transplant	2012
Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury. Canadian journal of surgery. Journal canadien de chirurgie, 2013, Volume: 56, Issue:1 Topics: Animals; Biomarkers; Cyclic GMP; Enzyme Inhibitors; Immunohistochemistry; Infusions, Parenteral; Kid	2013
Effect of celecoxib and L-NAME on global ischemia-reperfusion injury in the rat hippocampus. Drug and chemical toxicology, 2013, Volume: 36, Issue:4 Topics: Animals; Caspase 3; Celecoxib; Cyclooxygenase 2 Inhibitors; Hippocampus; Neuroprotective Agents; NG-	2013
The effects of antioxidants and nitric oxide modulators on hepatic ischemic-reperfusion injury in rats. Journal of Korean medical science, 2002, Volume: 17, Issue:4 Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Catalase; Enzyme Inhibitors; Liver; Male; Malondiald	2002
Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. Neurosurgery, 2002, Volume: 51, Issue:1 Topics: Animals; Ischemia; Male; Malondialdehyde; Microscopy, Electron; Myelin Sheath; Nitrates; Nitrites; P	2002
The relationship of hepatic tissue oxygenation with nitric oxide metabolism in ischemic preconditioning of the liver. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:12 Topics: Alanine Transaminase; Animals; Electron Transport Complex IV; Ischemic Preconditioning; Liver; Nitra	2002
Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714. Transplantation, 2003, Mar-15, Volume: 75, Issue:5 Topics: Amidines; Animals; Apoptosis; Aspartate Aminotransferases; DNA; Enzyme Inhibitors; Female; Hepatocyt	2003
Induction of LOX-1 and iNOS expressions by ischemia-reperfusion of rat kidney and the opposing effect of L-arginine. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:6 Topics: Animals; Arginine; Biopterins; Gene Expression Regulation; Kidney; Male; Nitrates; Nitric Oxide Synt	2003
Role of nitric oxide and peroxynitrite anion in lung injury induced by intestinal ischemia-reperfusion in rats. World journal of gastroenterology, 2003, Volume: 9, Issue:6 Topics: Animals; Anions; Lung; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric	2003
Effects of iNOS-related NO on hearts exposed to liposoluble iron. Free radical research, 2003, Volume: 37, Issue:7 Topics: Animals; Arginine; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Immunoblotting; Iron	2003
The effect of alprostadil on ischemia-reperfusion injury of peripheral nerve in rats. Pharmacological research, 2004, Volume: 49, Issue:1 Topics: Alprostadil; Animals; Disease Models, Animal; Femoral Artery; Femoral Vein; Injections, Intravenous;	2004
Wine polyphenols induce hypotension, and decrease cardiac reactivity and infarct size in rats: involvement of nitric oxide. British journal of pharmacology, 2004, Volume: 142, Issue:4 Topics: Administration, Oral; Aldehydes; Animals; Blood Pressure; Blotting, Western; Carbachol; Coronary Cir	2004
Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils. Journal of neurochemistry, 2004, Volume: 90, Issue:1 Topics: Administration, Oral; Animals; Antioxidants; Brain Chemistry; Cell Nucleus; Crataegus; Disease Model	2004
Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide. American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:5 Topics: Actins; Administration, Inhalation; Animals; Apoptosis; Blotting, Western; Carbon Monoxide; Carboxyh	2004
Attenuation of ischemia/reperfusion-induced intestinal injury by oleo-resin from Copaifera langsdorffii in rats. Life sciences, 2004, Sep-03, Volume: 75, Issue:16 Topics: Analysis of Variance; Animals; Balsams; Catalase; Glutathione; Ileum; Male; Malondialdehyde; Nitrite	2004
Nitric oxide-releasing aspirin derivative, NCX 4016, promotes reparative angiogenesis and prevents apoptosis and oxidative stress in a mouse model of peripheral ischemia. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:11 Topics: Animals; Apoptosis; Aspirin; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Ma	2004
Nitrite-derived nitric oxide formation following ischemia-reperfusion injury in kidney. American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1 Topics: Animals; Electron Spin Resonance Spectroscopy; Hemoglobins; Kidney; Male; Nitric Oxide; Nitric Oxide	2005
Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury. Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:3 Topics: Animals; Aspartate Aminotransferases; Creatinine; Glycoside Hydrolases; Isoenzymes; Kidney; Male; Mi	2005
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. The Journal of clinical investigation, 2005, Volume: 115, Issue:5 Topics: Animals; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Liver; Membrane Proteins; Mice; Mice, Inbre	2005
Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injury. Shock (Augusta, Ga.), 2005, Volume: 24, Issue:2 Topics: Animals; Antioxidants; Glutathione; Hypothermia; Hypothermia, Induced; Intestinal Mucosa; Intestines	2005
Nitrite-derived nitric oxide by xanthine oxidoreductase protects the liver against ischemia-reperfusion injury. Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:3 Topics: Adenosine Triphosphate; Alanine Transaminase; Allopurinol; Animals; Enzyme Inhibitors; Female; Liver	2005
Endothelial dysfunction in trauma patients: a preliminary communication. Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3 Topics: Adult; Body Mass Index; Endothelium, Vascular; Female; Hemodynamics; Humans; Male; Middle Aged; Nitr	2005
Real-time monitoring of nitric oxide and blood flow during ischemia-reperfusion in the rat testis. Molecular and cellular biochemistry, 2006, Volume: 286, Issue:1-2 Topics: Animals; Arginine; Blood Flow Velocity; Enzyme Inhibitors; Laser-Doppler Flowmetry; Male; Malondiald	2006
Effect of caffeic acid phenethyl ester on survival of axial pattern flaps in rats with ischaemia-reperfusion injuries. Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2006, Volume: 40, Issue:2 Topics: Animals; Antioxidants; Caffeic Acids; Graft Survival; Male; Nitrates; Nitrites; Phenylethyl Alcohol;	2006
Effects of co-administration of an iNOS inhibitor with a broad-spectrum reactive species scavenger in rat renal ischemia/reperfusion injury. Nephron. Experimental nephrology, 2006, Volume: 103, Issue:3 Topics: Animals; Drug Combinations; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Kidney; Kidney	2006
Mitochondrial NOS upregulation during renal I/R causes apoptosis in a peroxynitrite-dependent manner. Kidney international, 2006, Volume: 69, Issue:8 Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Cytochromes c; Densitometry; Enzyme Inhibitors; I	2006
Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult. Experimental neurology, 2006, Volume: 200, Issue:2 Topics: Animals; Brain Infarction; Calcium; Catalase; Cell Death; Disease Models, Animal; Hypothyroidism; Im	2006
Delayed energy protection of ischemic preconditioning on hepatic ischemia/reperfusion injury in rats. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2006, Volume: 38, Issue:2 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine Transaminase; Animal	2006
eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. Circulation research, 2006, Jul-07, Volume: 99, Issue:1 Topics: Animals; Biological Availability; Biopterins; Diabetes Mellitus, Type 2; Drug Synergism; Genetic The	2006
Allopurinol and enalapril failed to conserve urinary NOx and sodium in ischemic acute renal failure in spontaneously hypertensive rats. American journal of nephrology, 2006, Volume: 26, Issue:4 Topics: Acute Kidney Injury; Allopurinol; Animals; Antihypertensive Agents; Antimetabolites; Drug Combinatio	2006
Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis. Nature chemical biology, 2006, Volume: 2, Issue:9 Topics: Animals; Catalysis; Ceruloplasmin; Endocrine System; Erythrocytes; Female; Homeostasis; Humans; In V	2006
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA). American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2 Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines;	2007
Influence of physical preconditioning on the responsiveness of rat pulmonary artery after pulmonary ischemia/reperfusion. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 147, Issue:3 Topics: Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Lung; Nitrates; Nitrites; Ph	2007
Beneficial effects of supplemental nitric oxide donor given during reperfusion period in reperfusion-induced lung injury. The Thoracic and cardiovascular surgeon, 2006, Volume: 54, Issue:7 Topics: Analysis of Variance; Animals; Heart-Lung Transplantation; Lung; Lung Transplantation; Neutrophils;	2006
Melatonin reduces ventricular arrhythmias and preserves capillary perfusion during ischemia-reperfusion events in cardiomyopathic hamsters. Journal of pineal research, 2007, Volume: 42, Issue:1 Topics: Angiotensin II; Animals; Antioxidants; Arrhythmias, Cardiac; Arterioles; Capillary Permeability; Car	2007
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:2 Topics: Animals; Disease Models, Animal; Kidney; Male; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide	2007
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3 Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Capillaries; Curcuma; Curcumi	2007
Formation and role of plasma S-nitrosothiols in liver ischemia-reperfusion injury. Free radical biology & medicine, 2007, Mar-15, Volume: 42, Issue:6 Topics: Acetylcysteine; Animals; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Electr	2007
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America, 2007, May-01, Volume: 104, Issue:18 Topics: Animals; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitrites; Receptor, Br	2007
Nitric oxide generation is associated with an unbalance of protein tyrosine phosphatases during liver transplantation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2007, Volume: 61, Issue:4 Topics: Animals; Apoptosis; Caspase 3; DNA Fragmentation; Female; Liver Transplantation; Nitrates; Nitric Ox	2007
In which period of injury is resveratrol treatment effective: ischemia or reperfusion? Annals of vascular surgery, 2007, Volume: 21, Issue:3 Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; H	2007
Peroxynitrite decomposition catalyst FeTMPyP provides partial protection against intestinal ischemia and reperfusion injury in infant rats. Pediatric research, 2007, Volume: 62, Issue:1 Topics: Animals; Animals, Suckling; Endothelial Cells; Glutathione; Intercellular Adhesion Molecule-1; Intes	2007
Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model. World journal of surgery, 2007, Volume: 31, Issue:8 Topics: Animals; Antioxidants; Capillary Permeability; Disease Models, Animal; Glutathione; Lung; Malondiald	2007
Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion. Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:6 Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Aspartate Aminotransferases; Ischemia	2006
Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer. The Journal of experimental medicine, 2007, Sep-03, Volume: 204, Issue:9 Topics: Aconitate Hydratase; Administration, Oral; Animals; Cytochromes c; Cytoprotection; Electron Transpor	2007
Nitrite does not provide additional protection to thrombolysis in a rat model of stroke with delayed reperfusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:3 Topics: Animals; Disease Models, Animal; Magnetic Resonance Imaging; Male; Nitrites; Rats; Rats, Sprague-Daw	2008
In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion. Annals of vascular surgery, 2007, Volume: 21, Issue:5 Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascu	2007
The effects of vitamin E on lipid peroxidation, nitric oxide production and superoxide dismutase expression in hyperglycemic rats with cerebral ischemia-reperfusion injury. Turkish neurosurgery, 2007, Volume: 17, Issue:2 Topics: Animals; Antioxidants; Blood Pressure; Brain Diseases; Diabetes Mellitus, Experimental; Hyperglycemi	2007
Ginkgo biloba (EGb 761) usage attenuates testicular injury induced by testicular ischemia/reperfusion in rats. International urology and nephrology, 2008, Volume: 40, Issue:3 Topics: Analysis of Variance; Animals; Ginkgo biloba; Male; Malondialdehyde; Nitrates; Nitrites; Plant Extra	2008
How DMSO, a widely used solvent, affects spinal cord injury. Annals of vascular surgery, 2008, Volume: 22, Issue:1 Topics: Animals; Aorta, Abdominal; Dimethyl Sulfoxide; Disease Models, Animal; Free Radical Scavengers; Liga	2008
Pharmacological induction of heme oxygenase-1 inhibits iNOS and oxidative stress in renal ischemia-reperfusion injury. Transplantation proceedings, 2007, Volume: 39, Issue:10 Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Induction; Heme Oxygenase-1; Isoe	2007
Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder. Molecular and cellular biochemistry, 2008, Volume: 311, Issue:1-2 Topics: Animals; Glycine; Leukocyte Elastase; Male; Malondialdehyde; Nitrates; Nitrites; Proteinase Inhibito	2008
Activated protein C prevents deleterious effects of remote reperfusion injury caused by intestinal ischemia on wound healing in the left colonic anastomoses: an experimental study in the murine model. American journal of surgery, 2008, Volume: 196, Issue:5 Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Chi-Square Distribution; Glutathione; Glutathi	2008
The effects of administration of nitric oxide inhibitors during small bowel preservation and reperfusion. Transplantation, 1994, Dec-27, Volume: 58, Issue:12 Topics: Animals; Arginine; Blood Urea Nitrogen; Glutaminase; Graft Survival; Intestinal Mucosa; Intestine, S	1994
Dietary nucleotides: effects on the gastrointestinal system in swine. The Journal of nutrition, 1994, Volume: 124, Issue:1 Suppl Topics: Adenosine; Animals; Animals, Newborn; Animals, Suckling; Diet; Digestive System; DNA; Granulocytes;	1994
Nafamostat mesilate prevents warm ischemia-reperfusion injury in canine pancreas autotransplantation. Transplantation proceedings, 1995, Volume: 27, Issue:6 Topics: Animals; Benzamidines; Dogs; Guanidines; Male; Nitrites; Pancreas; Pancreas Transplantation; Proteas	1995
Changes in plasma nitrite/nitrate level after orthotopic liver transplantation in pigs. Transplantation proceedings, 1996, Volume: 28, Issue:3 Topics: Animals; Aspartate Aminotransferases; Biomarkers; Graft Survival; Hyaluronic Acid; Liver; Liver Tran	1996
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine. Transplantation proceedings, 1996, Volume: 28, Issue:3 Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; N	1996
Glyceryl trinitrate prevents neutrophil activation but not thromboxane release following ischaemia-reperfusion injury. The British journal of surgery, 1996, Volume: 83, Issue:8 Topics: Animals; Aortic Diseases; Arterial Occlusive Diseases; Blood Pressure; Leukocyte Count; Lung; Male;	1996
Hypothermia suppresses nitric oxide elevation during reperfusion after focal cerebral ischemia in rats. Neuroscience letters, 1996, Dec-06, Volume: 220, Issue:1 Topics: Animals; Body Temperature; Brain Ischemia; Hemoglobins; Hypothermia, Induced; Jugular Veins; Male; N	1996
21-Aminosteroids block neutrophil infiltration and provide liver protection independent of NO2-/NO3- levels. The Journal of surgical research, 1996, Volume: 66, Issue:2 Topics: Animals; Antioxidants; Liver; Male; Neutrophils; Nitrates; Nitrites; Peroxidase; Pregnatrienes; Rats	1996
Improvement of cardiac output and liver blood flow and reduction of pulmonary vascular resistance by intravenous infusion of L-arginine during the early reperfusion period in pig liver transplantation. Transplantation, 1997, May-15, Volume: 63, Issue:9 Topics: Animals; Arginine; Blood Urea Nitrogen; Cardiac Output; Female; Hemodynamics; Humans; Hypertension,	1997
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury. The Journal of surgical research, 1997, Volume: 69, Issue:2 Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemo	1997
Effect of exogenous L-arginine for hepatic ischemia-reperfusion injury in an isolated rat liver in vitro. Transplantation proceedings, 1998, Volume: 30, Issue:7 Topics: Animals; Arginine; In Vitro Techniques; Liver; Male; Nitrates; Nitrites; Organ Preservation; Rats; R	1998
NO modulates P-selectin and ICAM-1 mRNA expression and hemodynamic alterations in hepatic I/R. The American journal of physiology, 1998, Volume: 275, Issue:6 Topics: Alanine Transaminase; Animals; Cell Adhesion Molecules; Hemodynamics; Intercellular Adhesion Molecul	1998
Intravenous glycine improves survival in rat liver transplantation. The American journal of physiology, 1999, Volume: 276, Issue:4 Topics: Adenosine; Allopurinol; Animals; Female; Gadolinium; Glutathione; Glycine; Graft Survival; Hepatecto	1999
Intestinal ischemia-reperfusion leads to platelet dysfunction. Thrombosis research, 1999, Jun-15, Volume: 94, Issue:6 Topics: Adenosine Diphosphate; Animals; Biomarkers; Blood Platelet Disorders; Blood Platelets; Collagen; Int	1999
Effect of ischemic preconditioning on endothelial dysfunction and granulocyte adhesion in isolated guinea-pig hearts subjected to ischemia/reperfusion. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:4 Topics: Acetylcholine; Animals; Cell Adhesion; Coronary Vessels; Drug Interactions; Endothelium, Vascular; F	1999
Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion. Shock (Augusta, Ga.), 2000, Volume: 13, Issue:3 Topics: Alanine Transaminase; Animals; Down-Regulation; Enzyme Inhibitors; Interleukin-1; Ischemia; Leukocyt	2000
Myocardial ischemia-reperfusion injury in estrogen receptor-alpha knockout and wild-type mice. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5 Topics: Animals; Calcium; Coronary Circulation; Edema, Cardiac; Estrogen Receptor alpha; Heart Rate; In Vitr	2000
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:9 Topics: Animals; Blood Pressure; Catalysis; Celiac Artery; Disease Models, Animal; Endothelium, Vascular; Fe	2000
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury. Cardiovascular research, 2000, Aug-18, Volume: 47, Issue:3 Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Aorta; Fluorescent Antibody Technique,	2000
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury. Brain research, 2000, Sep-01, Volume: 875, Issue:1-2 Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Edema; Cerebral Arteries; Cyclic N-Oxides; Free R	2000
Protective effects of melatonin in ischemic brain injury. Journal of pineal research, 2000, Volume: 29, Issue:4 Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scaveng	2000
Neuroprotective effects of Ginkgo biloba extract in brain ischemia are mediated by inhibition of nitric oxide synthesis. Life sciences, 2000, Oct-20, Volume: 67, Issue:22 Topics: Administration, Oral; Animals; Brain; Brain Edema; Cell Death; Dose-Response Relationship, Drug; Ger	2000
Postischemic anti-inflammatory effects of bradykinin preconditioning. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Bradykinin Receptor Antagonists; Capillaries; Cell Ad	2001
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion. British journal of pharmacology, 2001, Volume: 132, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Catalysis; Cytokines;	2001
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:3 Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme In	2001
Effects of dietary phytoestrogen on global myocardial ischemia-reperfusion injury in isolated female rat hearts. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3 Topics: Animals; Blood Flow Velocity; Calcium; Coronary Circulation; Diet; Estradiol; Estrogens, Non-Steroid	2001
Inhibition of nitric oxide synthesis by L-name exacerbates acute lung injury induced by hepatic ischemia-reperfusion. Shock (Augusta, Ga.), 2001, Volume: 16, Issue:3 Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibito	2001
Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl. Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6 Topics: Animals; Anions; Dexamethasone; Gene Expression; Glucocorticoids; Intercellular Adhesion Molecule-1;	2001
Effect of exogenous melatonin on hepatic energetic status during ischemia/reperfusion: possible role of tumor necrosis factor-alpha and nitric oxide. The Journal of surgical research, 2001, Volume: 100, Issue:2 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotr	2001
Oxidative and nitrosative stress in acute renal ischemia. American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:5 Topics: Animals; Azoles; Blotting, Western; Cell Line; Cyclic N-Oxides; DNA Damage; Enzyme Inhibitors; Free	2001
Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury. Antioxidants & redox signaling, 2001, Volume: 3, Issue:5 Topics: Animals; Blotting, Western; Down-Regulation; Epidermal Growth Factor; Heparin-binding EGF-like Growt	2001
Inhibition of nitric oxide synthase does not influence urinary nitrite plus nitrate excretion after renal ischemic injury. Langenbeck's archives of surgery, 2002, Volume: 386, Issue:7 Topics: Animals; Disease Models, Animal; Ischemia; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Est	2002
Nitric oxide in cold and warm ischemia reperfusion renal transplantation. Transplantation proceedings, 2002, Volume: 34, Issue:1 Topics: Animals; Creatinine; Dogs; Kidney; Kidney Transplantation; Nephrectomy; Nitrates; Nitric Oxide; Nitr	2002
A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfusion injury in the pig liver. Transplantation, 2002, May-15, Volume: 73, Issue:9 Topics: Amidines; Animals; Aspartate Aminotransferases; Enzyme Inhibitors; Female; Heterocyclic Compounds, 2	2002
Role of nitric oxide in the oxidant stress during ischemia/reperfusion injury of the liver. Life sciences, 1992, Volume: 50, Issue:23 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Kupffer Cells; Liver; Male; Nitrates; Nitric Oxide; N	1992

nitrites and Reperfusion Injury