Page last updated: 2024-10-19

nitrites and Peripheral Vascular Diseases

nitrites has been researched along with Peripheral Vascular Diseases in 20 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Peripheral Vascular Diseases: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.

Research Excerpts

ExcerptRelevanceReference
"We explored the efficacy of intravenous therapy with propionyl L-carnitine in patients with both peripheral arterial disease (PAD) and chronic renal insufficiency requiring haemodialysis."5.12A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis. ( Celotta, G; Di Pino, L; Fallico, R; Fatuzzo, P; Ferrante, M; Massimiliano, A; Neri, S; Oliveri Conti, G; Pennisi, G; Rapisarda, F; Signorelli, SS, 2006)
"Dipyridamole treatment quickly restored ischaemic hindlimb blood flow, increased vascular density and cell proliferation, and enhanced collateral artery perfusion compared with control treatments."1.36Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway. ( Branch, B; Hood, J; Illum, S; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Teng, X; Thoma, S; Venkatesh, PK, 2010)
" Our data support the effects of statins in vivo that have been demonstrated on the endothelium ex vivo, suggesting a beneficial effect by acting on the initial processes that trigger the disease, reducing oxidative stress (increase in the bioavailability of nitric oxide as peroxynitrite levels decrease) and curtailing the inflammatory processes which perpetuate the disease."1.35In vivo confirmation of the role of statins in reducing nitric oxide and C-reactive protein levels in peripheral arterial disease. ( Aguilar, EM; Casariego, CV; García, FA; González, AF; Miralles, Jde H; Moreno, SB, 2009)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's2 (10.00)18.2507
2000's7 (35.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aguilar, EM1
Miralles, Jde H1
González, AF1
Casariego, CV1
Moreno, SB1
García, FA1
Allen, JD2
Miller, EM1
Schwark, E1
Robbins, JL1
Duscha, BD1
Annex, BH1
de Haro Miralles, J1
Martínez-Aguilar, E1
Florez, A1
Varela, C1
Bleda, S1
Acin, F1
Venkatesh, PK1
Pattillo, CB1
Branch, B1
Hood, J1
Thoma, S1
Illum, S1
Pardue, S1
Teng, X1
Patel, RP1
Kevil, CG2
Giordano, T1
MARCHE, J1
KRAUCHER, GK1
HUEBER, EF1
THALER, H1
WICK, E1
POLETTI, RA1
SAMUELS, SS2
DE LA PIERRE, M1
BARBERA, G1
COSTA, P1
ABRAMSON, DI1
KOLLMANN, HJ1
de Berrazueta, JR1
Sampedro, I1
Garcia-Unzueta, MT1
Llorca, J1
Bustamante, M1
Amado, JA1
PADERNACHT, ED1
Yamada, K1
Suzuki, E1
Nakaki, T1
Watanabe, S1
Kanba, S1
Signorelli, SS1
Fatuzzo, P1
Rapisarda, F1
Neri, S1
Ferrante, M1
Oliveri Conti, G1
Fallico, R1
Di Pino, L1
Pennisi, G1
Celotta, G1
Massimiliano, A1
Loffredo, L1
Marcoccia, A1
Pignatelli, P1
Andreozzi, P1
Borgia, MC1
Cangemi, R1
Chiarotti, F1
Violi, F1
Arosio, E1
Cuzzolin, L1
De Marchi, S1
Minuz, P1
Degan, M1
Crivellente, F1
Zannoni, M1
Benoni, G1
Ferlito, S1
Gallina, M1
Catassi, S1
Bisicchia, A1
Di Salvo, MM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Placebo Controlled, Pilot Trial of Statin Use in Burn Patients[NCT00978419]Phase 240 participants (Actual)Interventional2010-03-31Completed
Effects of Trehalose and a Mix of Polyphenols on Endothelial Function, Oxidative Stress, Platelet Function and Autophagy in Vasculopathic Patients[NCT04061070]80 participants (Actual)Interventional2019-12-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrites and Peripheral Vascular Diseases

ArticleYear
Nitrite and nitric oxide metabolism in peripheral artery disease.
    Nitric oxide : biology and chemistry, 2012, May-15, Volume: 26, Issue:4

    Topics: Animals; Humans; Hypoxia; Nitric Oxide; Nitrites; Peripheral Vascular Diseases

2012

Trials

5 trials available for nitrites and Peripheral Vascular Diseases

ArticleYear
Effect of transdermal nitroglycerin on inflammatory mediators in patients with peripheral atherosclerotic vascular disease.
    American heart journal, 2003, Volume: 146, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Biomarkers; C-Re

2003
Aconiti tuber increases plasma nitrite and nitrate levels in humans.
    Journal of ethnopharmacology, 2005, Jan-04, Volume: 96, Issue:1-2

    Topics: Aconitum; Adult; Aged; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Humans;

2005
A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis.
    Drugs & aging, 2006, Volume: 23, Issue:3

    Topics: Aged; Aldehydes; Carnitine; Double-Blind Method; Humans; Malondialdehyde; Middle Aged; Nitrates; Nit

2006
Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease.
    European heart journal, 2007, Volume: 28, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antioxidants; Bio

2007
Increased endogenous nitric oxide production induced by physical exercise in peripheral arterial occlusive disease patients.
    Life sciences, 1999, Volume: 65, Issue:26

    Topics: Aged; Arterial Occlusive Diseases; Cell Adhesion; Exercise Therapy; Humans; Iloprost; Infusions, Int

1999

Other Studies

14 other studies available for nitrites and Peripheral Vascular Diseases

ArticleYear
In vivo confirmation of the role of statins in reducing nitric oxide and C-reactive protein levels in peripheral arterial disease.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2009, Volume: 37, Issue:4

    Topics: Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cholesterol; Female; Heptanoic Acids; Hum

2009
Plasma nitrite response and arterial reactivity differentiate vascular health and performance.
    Nitric oxide : biology and chemistry, 2009, Volume: 20, Issue:4

    Topics: Aged; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Forearm; Humans; Middle Aged; Nit

2009
Nitric oxide: link between endothelial dysfunction and inflammation in patients with peripheral arterial disease of the lower limbs.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Brachial Artery; C-Reactive Protein; Case-Control Studie

2009
Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.
    Cardiovascular research, 2010, Mar-01, Volume: 85, Issue:4

    Topics: Animals; Cell Division; Chronic Disease; Cyclic AMP-Dependent Protein Kinases; Dipyridamole; Dose-Re

2010
[Therapy of vascular syndromes, particularly arteriolar, with pentaerythritol tetranitrate].
    Angeiologie et annales de la Societe francaise d'angeiologie et d'histopathologie, 1952, Dec-01, Volume: 59, Issue:22

    Topics: Nitrites; Pentaerythritol Tetranitrate; Peripheral Vascular Diseases; Syndrome; Vascular Diseases

1952
[Therapy of peripheral circulatory disorders with tetraethylammonium nitrite].
    Acta neurovegetativa, 1953, Volume: 8, Issue:1

    Topics: Cardiovascular Diseases; Nitrites; Peripheral Vascular Diseases; Tetraethylammonium; Vascular Diseas

1953
[Peripheral arterial circulatory disorders and therapy. I. Rheoangiographic registration of the effect of nitroglycerin preparations in healthy subjects].
    Zeitschrift fur Kreislaufforschung, 1956, Volume: 45, Issue:11-12

    Topics: Healthy Volunteers; Nitrites; Nitroglycerin; Peripheral Arterial Disease; Peripheral Vascular Diseas

1956
[Treatment of coronary insufficiency, thromboangilitis & cerebral arteritis with intravenous sodium nitrate].
    El Dia medico, 1957, May-02, Volume: 29, Issue:26

    Topics: Arteritis; Brain; Coronary Disease; Humans; Nitrates; Nitrites; Peripheral Vascular Diseases; Thromb

1957
Sustained-action peritrate in arterial insufficiency of the lower extremities.
    New York state journal of medicine, 1958, Apr-15, Volume: 58, Issue:8

    Topics: Lower Extremity; Nitrites; Pentaerythritol Tetranitrate; Peripheral Vascular Diseases; Vascular Dise

1958
[Variations of oscillometric indices of the extremities induced by nitroglycerin in healthy subjects and in arteriopathic patients].
    Minerva cardioangiologica, 1959, Volume: 7

    Topics: Extremities; Healthy Volunteers; Humans; Nitrites; Nitroglycerin; Peripheral Vascular Diseases; Vasc

1959
DRUGS USED IN PERIPHERAL VASCULAR DISEASES.
    The American journal of cardiology, 1963, Volume: 12

    Topics: Deoxyribonuclease I; Dihydroergotoxine; Endopeptidases; Ergot Alkaloids; Ganglionic Blockers; Histam

1963
[Treatment of spastic vascular diseases].
    Die Medizinische, 1955, Jan-29, Volume: 5

    Topics: Alkaloids; Atropa belladonna; Barbiturates; Humans; Muscle Spasticity; Nitrites; Papaverine; Parasym

1955
Peritrate in peripheral arterial diseases.
    Angiology, 1952, Volume: 3, Issue:1

    Topics: Nitrites; Pentaerythritol Tetranitrate; Peripheral Arterial Disease; Peripheral Vascular Diseases; V

1952
Nitrite plasma levels in normolipemic and hypercholesterolemic patients with peripheral occlusive arteriopathy.
    Panminerva medica, 1999, Volume: 41, Issue:4

    Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Hypercholesterolemia; Leg; Lipids; Male; Middle A

1999