nitrites has been researched along with Pain in 37 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was carried out to investigate the effect of amentoflavone isolated from methanolic root extract of CF on lipopolysaccharide (LPS)-induced neuroinflammatory cascade of events associated to the oxidative and nitrative stress, and TNF-α production in rat astrocytoma cell line (C6) and human monocytic leukemia cell line (THP-1), respectively." | 7.79 | Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells. ( Adeyemi, OO; Chaturvedi, JP; Ishola, IO; Narender, T; Rai, S; Rajasekar, N; Shukla, R, 2013) |
| "Intrathecal administration of alpha(2) adrenergic agonists, such as clonidine, is capable of alleviating neuropathic pain." | 7.70 | Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain. ( Chen, SR; Eisenach, J; Pan, HL; Xu, Z, 2000) |
| "Pretreatment with substance P (1-7) (400 pmol) produced a significant reduction on the elevated concentrations of glutamate and NO metabolites evoked by i." | 5.34 | Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade. ( Komatsu, T; Kuwahata, H; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M; Watanabe, C, 2007) |
| " In vivo animal models of phorbol 12-myristate 13-acetate (TPA)-induced ear edema and acetic acid-induced writhing response tests were used to analyze the in vivo anti-inflammatory effects and anti-nociceptive effects of DP extract, respectively." | 3.83 | Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway. ( Akram, M; Bae, ON; Kim, CY; Kim, ES; Kim, KA; Lee, JS; Syed, AS, 2016) |
| "More studies are still warranted in similar rodent models of pain and depression, so, that the present findings can be further substantiated to establish the clinical effectiveness of berberine in a subset of patients suffering from pain as well as depression." | 3.79 | Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model. ( Arora, V; Chopra, K, 2013) |
| "This study was carried out to investigate the effect of amentoflavone isolated from methanolic root extract of CF on lipopolysaccharide (LPS)-induced neuroinflammatory cascade of events associated to the oxidative and nitrative stress, and TNF-α production in rat astrocytoma cell line (C6) and human monocytic leukemia cell line (THP-1), respectively." | 3.79 | Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells. ( Adeyemi, OO; Chaturvedi, JP; Ishola, IO; Narender, T; Rai, S; Rajasekar, N; Shukla, R, 2013) |
| " The anti-nociceptive activities of MPP were measured using various experimental pain models including thermal nociception methods such as the tail immersion test and the hot plate test as well as chemical nociception methods like acetic acid-induced writhing test and formalin test." | 3.78 | Anti-inflammatory and anti-nociceptive properties of Prunus padus. ( Cha, DS; Choi, JH; Jeon, H, 2012) |
| "The results showed that the ethanolic extract of the Bougainvillea xbuttiana has significant anti-inflammatory and antinociceptive activities, by inhibition of nociception induced by acetic acid and paw oedema." | 3.78 | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Bougainvillea xbuttiana. ( Alvarez Perez Gil, AL; Barbosa Navarro, L; Patipo Vera, M; Petricevich, VL, 2012) |
| " Also, the development of morphine dependence as assessed by naloxone-precipitated withdrawal manifestations was reduced by co-administration of aminoguanidine." | 3.73 | Attenuation of morphine tolerance and dependence by aminoguanidine in mice. ( Abdel-Hady, RH; Abdel-Rahman, S; Abdel-Zaher, AO; Aly, SA; Hamdy, MM, 2006) |
| "Intrathecal administration of alpha(2) adrenergic agonists, such as clonidine, is capable of alleviating neuropathic pain." | 3.70 | Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain. ( Chen, SR; Eisenach, J; Pan, HL; Xu, Z, 2000) |
| "The pain was evaluated by visual analogue scale (VAS)." | 2.90 | Phonopheresis Associated with Nanoparticle Gel from Phyllanthus amarus Relieves Pain by Reducing Oxidative Stress and Proinflammatory Markers in Adults with Knee Osteoarthritis. ( Decha, P; Jiraporn, T; Kanokwan, K; Pichaya, J; Pisittawoot, A, 2019) |
| "The hypothesis of decreased nitric oxide (NO) bioavailability in sickle cell disease (SCD) proposes that multiple factors leading to decreased NO production and increased consumption contributes to vaso-occlusion, pulmonary hypertension, and pain." | 1.56 | Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments. ( Almeida, LEF; Darbari, DS; de Souza Batista, CM; Finkel, JC; Kamimura, S; Nettleton, MY; Quezado, ZMN; Smith, ML; Spornick, N; Wakim, P; Walek, E, 2020) |
| "Pretreatment with substance P (1-7) (400 pmol) produced a significant reduction on the elevated concentrations of glutamate and NO metabolites evoked by i." | 1.34 | Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade. ( Komatsu, T; Kuwahata, H; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M; Watanabe, C, 2007) |
| " Acute and chronic administration of 1% or 2." | 1.33 | Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain. ( Ahmadiani, A; Hassanzadeh, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (16.22) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 19 (51.35) | 29.6817 |
| 2010's | 9 (24.32) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Pușcașu, C | 1 |
| Ungurianu, A | 1 |
| Șeremet, OC | 1 |
| Andrei, C | 1 |
| Mihai, DP | 1 |
| Negreș, S | 1 |
| Decha, P | 1 |
| Kanokwan, K | 1 |
| Jiraporn, T | 1 |
| Pichaya, J | 1 |
| Pisittawoot, A | 1 |
| Almeida, LEF | 1 |
| Kamimura, S | 1 |
| de Souza Batista, CM | 1 |
| Spornick, N | 1 |
| Nettleton, MY | 1 |
| Walek, E | 1 |
| Smith, ML | 1 |
| Finkel, JC | 1 |
| Darbari, DS | 1 |
| Wakim, P | 1 |
| Quezado, ZMN | 1 |
| Khan, S | 1 |
| Shehzad, O | 1 |
| Chun, J | 1 |
| Kim, YS | 1 |
| Arora, V | 1 |
| Chopra, K | 1 |
| Akram, M | 1 |
| Kim, KA | 1 |
| Kim, ES | 1 |
| Syed, AS | 1 |
| Kim, CY | 1 |
| Lee, JS | 1 |
| Bae, ON | 1 |
| Jung, HJ | 1 |
| Song, YS | 1 |
| Lim, CJ | 1 |
| Park, EH | 1 |
| Rodriguez Peña, M | 1 |
| Alescio, L | 1 |
| Russell, A | 1 |
| Lourenco da Cunha, J | 1 |
| Alzu, G | 1 |
| Bardoneschi, E | 1 |
| BONNECARRERE, E | 1 |
| LOCKHART, J | 1 |
| Mehrotra, A | 1 |
| Shanbhag, R | 1 |
| Chamallamudi, MR | 1 |
| Singh, VP | 1 |
| Mudgal, J | 1 |
| Lee, KH | 1 |
| Kim, TH | 1 |
| Lee, WC | 1 |
| Kim, SH | 1 |
| Lee, SY | 1 |
| Lee, SM | 1 |
| Choi, JH | 1 |
| Cha, DS | 1 |
| Jeon, H | 1 |
| Alvarez Perez Gil, AL | 1 |
| Barbosa Navarro, L | 1 |
| Patipo Vera, M | 1 |
| Petricevich, VL | 1 |
| Ishola, IO | 1 |
| Chaturvedi, JP | 1 |
| Rai, S | 1 |
| Rajasekar, N | 1 |
| Adeyemi, OO | 1 |
| Shukla, R | 1 |
| Narender, T | 1 |
| De León, EJ | 2 |
| Alcaraz, MJ | 2 |
| Dominguez, JN | 2 |
| Charris, J | 2 |
| Terencio, MC | 2 |
| DURRER, D | 1 |
| Costa, B | 2 |
| Trovato, AE | 2 |
| Colleoni, M | 2 |
| Giagnoni, G | 2 |
| Zarini, E | 1 |
| Croci, T | 1 |
| Khattab, MM | 1 |
| El-Hadiyah, TM | 1 |
| Al-Shabanah, OA | 1 |
| Raza, M | 1 |
| Hassanzadeh, P | 1 |
| Ahmadiani, A | 1 |
| Escandell, JM | 1 |
| Recio, MC | 1 |
| Máñez, S | 1 |
| Giner, RM | 1 |
| Cerdá-Nicolás, M | 1 |
| Ríos, JL | 1 |
| Savaris, RF | 1 |
| Teixeira, LM | 1 |
| Torres, TG | 1 |
| Abdel-Zaher, AO | 1 |
| Hamdy, MM | 1 |
| Aly, SA | 1 |
| Abdel-Hady, RH | 1 |
| Abdel-Rahman, S | 1 |
| Siniscalco, D | 1 |
| Comelli, F | 1 |
| Sotgiu, ML | 1 |
| Maione, S | 1 |
| Rossi, F | 1 |
| Vareniuk, I | 1 |
| Pavlov, IA | 1 |
| Drel, VR | 1 |
| Lyzogubov, VV | 1 |
| Ilnytska, O | 1 |
| Bell, SR | 1 |
| Tibrewala, J | 1 |
| Groves, JT | 1 |
| Obrosova, IG | 1 |
| Joharchi, K | 1 |
| Jorjani, M | 1 |
| Uludag, O | 1 |
| Tunctan, B | 1 |
| Altug, S | 1 |
| Zengil, H | 1 |
| Abacioglu, N | 1 |
| Sakurada, T | 1 |
| Komatsu, T | 1 |
| Kuwahata, H | 1 |
| Watanabe, C | 1 |
| Orito, T | 1 |
| Sakurada, C | 1 |
| Tsuzuki, M | 1 |
| Sakurada, S | 1 |
| Regan, EA | 1 |
| Bowler, RP | 1 |
| Crapo, JD | 1 |
| Bruyneel, K | 1 |
| Kirby, B | 1 |
| Kimura, S | 1 |
| Watanabe, K | 1 |
| Yajiri, Y | 1 |
| Motegi, T | 1 |
| Masuya, Y | 1 |
| Shibuki, K | 1 |
| Uchiyama, S | 1 |
| Homma, T | 1 |
| Takahashi, HE | 1 |
| Xu, Z | 1 |
| Chen, SR | 1 |
| Eisenach, J | 1 |
| Pan, HL | 1 |
| Grover, VS | 1 |
| Sharma, A | 1 |
| Singh, M | 1 |
| Vetter, G | 1 |
| Geisslinger, G | 1 |
| Tegeder, I | 1 |
| Popescu, P | 1 |
| Gherasim, L | 1 |
1 review available for nitrites and Pain
| Article | Year |
|---|---|
Drug therapy for hypertension and ischemic heart disease.
Topics: Adrenergic beta-Agonists; Adult; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Glycosides; | 1980 |
1 trial available for nitrites and Pain
| Article | Year |
|---|---|
Phonopheresis Associated with Nanoparticle Gel from Phyllanthus amarus Relieves Pain by Reducing Oxidative Stress and Proinflammatory Markers in Adults with Knee Osteoarthritis.
Topics: Adult; Aged; Antioxidants; Biomarkers; Gels; Humans; Inflammation Mediators; Middle Aged; Nanopartic | 2019 |
35 other studies available for nitrites and Pain
| Article | Year |
|---|---|
The Influence of Sildenafil-Metformin Combination on Hyperalgesia and Biochemical Markers in Diabetic Neuropathy in Mice.
Topics: Animals; Biomarkers; Diabetes Mellitus; Diabetic Neuropathies; Hyperalgesia; Hypoglycemic Agents; In | 2023 |
Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments.
Topics: Adult; Anemia, Sickle Cell; Animals; Biological Availability; Cyclic GMP; Disease Models, Animal; Hu | 2020 |
Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades.
Topics: Acute Disease; Adenosine Triphosphate; Analgesics; Animals; Chronic Disease; Coumarins; Cyclic AMP R | 2013 |
Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model.
Topics: Animals; Berberine; Caspase 3; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Hippoc | 2013 |
Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Araliaceae; Chloroform; Cytokines; Dinop | 2016 |
Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of an ethanol extract of Salvia plebeia R. Brown.
Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; B | 2009 |
Predictors of improved seminal parameters and fertility after varicocele repair in young adults.
Topics: Adolescent; Adult; Fertility; Humans; Male; Nitrites; Organ Size; Pain; Predictive Value of Tests; S | 2009 |
Some considerations on the treatment of flank pain syndromes with amyl nitrite.
Topics: Amyl Nitrite; Back Pain; Humans; Lumbosacral Region; Nitrites; Pain | 1945 |
Treatment of hepato-vesicular colic attack with amyl nitrite.
Topics: Amyl Nitrite; Bile Duct Diseases; Biliary Tract; Gallbladder Diseases; Humans; Nitrites; Pain | 1946 |
Ameliorative effect of caffeic acid against inflammatory pain in rodents.
Topics: Acetates; Animals; Behavior, Animal; Caffeic Acids; Carrageenan; Formaldehyde; Inflammation; Lipopol | 2011 |
Anti-inflammatory and analgesic effects of human placenta extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Blotting, Western; Carrageena | 2011 |
Anti-inflammatory and anti-nociceptive properties of Prunus padus.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Edema; Formaldehyde; H | 2012 |
Anti-inflammatory and antinociceptive activities of the ethanolic extract of Bougainvillea xbuttiana.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Cytokines | 2012 |
Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Astrocytoma; Biflavonoids; Carrageenan; Cell Line; C | 2013 |
1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; B | 2003 |
[Therapy of stenocardiac pains with nitroglycerin].
Topics: Angina Pectoris; Nitrites; Nitroglycerin; Pain | 1960 |
A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats.
Topics: Abdominal Injuries; Administration, Oral; Animals; Arthritis, Experimental; Blood Platelets; Cell Li | 2003 |
Effect of the cannabinoid CB1 receptor antagonist, SR141716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve.
Topics: Analysis of Variance; Animals; Blotting, Western; Cannabinoid Receptor Antagonists; Constriction; De | 2005 |
Modification by L-NAME of codeine induced analgesia: possible role of nitric oxide.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Codeine; Dose-Response Relationship, Drug; Drug | 2004 |
Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain.
Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Immunohistochemistry; Inflammation; Irritan | 2006 |
Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experiment | 2006 |
Bladder tenderness as a physical sign for diagnosing cystitis in women.
Topics: Case-Control Studies; Cystitis, Interstitial; Female; Humans; Likelihood Functions; Nitrites; Pain; | 2006 |
Attenuation of morphine tolerance and dependence by aminoguanidine in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Dizocilpine Maleate; Dru | 2006 |
AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Apoptosis; Arachidonic Acids; bcl-2-Associated X Protein; Behavior, Animal; Blo | 2006 |
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
Topics: Anesthesia; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies; | 2007 |
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines; | 2007 |
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme I | 2007 |
Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Glutamic Acid; Male; Morphine; N-Methylaspart | 2007 |
Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury.
Topics: Age Factors; Cartilage, Articular; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Female; | 2008 |
Chest pain with normal coronary arteries.
Topics: Angina Pectoris; Coronary Angiography; Humans; Nitrites; Pain; Reference Values; Thorax | 1980 |
Cerebrospinal fluid nitric oxide metabolites in painful diseases.
Topics: Adult; Aged; Aged, 80 and over; Aging; Appendicitis; Female; Fractures, Bone; Humans; Lumbosacral Re | 1999 |
Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Male; Muscarinic Antagonists; Nicotinic Antagonists; | 2000 |
Role of nitric oxide in diabetes-induced attenuation of antinociceptive effect of morphine in mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Female; Guanidines; Male; Mice; Morphi | 2000 |
Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation.
Topics: Animals; Dinoprostone; Glutamic Acid; Glycerol; Lactic Acid; Male; Microdialysis; Nitrates; Nitric O | 2001 |
[Current problems in diagnosis and treatment of angina pectoris].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angiography; Anticoagulants; Benzofurans; Coronary Ang | 1972 |