nitrites has been researched along with Osteoarthritis in 25 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pterostilbene has been reported as a potential drug to inhibit oxidative stress and inflammation." | 7.85 | Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway. ( Lin, JP; Liu, HX; Sheng, SR; Xu, H; Xue, EX; Zhang, Y; Zhou, YL, 2017) |
| "Curcumin (Cur) and bisdemethoxycurcumin (BDMC), extracted from Curcuma longa, are poorly water-soluble polyphenol compounds that have shown anti-inflammatory potential for the treatment of osteoarthritis." | 7.81 | Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. ( Chang, HI; Chen, CN; Chen, PJ; Lin, YJ; Shi, CS; Su, YH; Yeh, CC, 2015) |
| "Pterostilbene has been reported as a potential drug to inhibit oxidative stress and inflammation." | 3.85 | Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway. ( Lin, JP; Liu, HX; Sheng, SR; Xu, H; Xue, EX; Zhang, Y; Zhou, YL, 2017) |
| "Curcumin (Cur) and bisdemethoxycurcumin (BDMC), extracted from Curcuma longa, are poorly water-soluble polyphenol compounds that have shown anti-inflammatory potential for the treatment of osteoarthritis." | 3.81 | Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. ( Chang, HI; Chen, CN; Chen, PJ; Lin, YJ; Shi, CS; Su, YH; Yeh, CC, 2015) |
| "SMT significantly reduced GAGs, hydroxyproline, matrix metalloproteinase (MMP)-13, tumour necrosis factor alpha (TNF-α), prostaglindin E2 (PGE2 ) and nitrite release in stimulated rabbit cartilage media indicating chondroprotective and anti-inflammatory effects of SMT in osteoarthritis (OA)." | 3.80 | Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis. ( Balaganur, V; Kumar, D; Kumari, RR; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK, 2014) |
| "To evaluate the in vivo therapeutic efficacy of N-iminoethyl-L-lysine (L-NIL), a selective inhibitor of inducible nitric oxide synthase (iNOS), on the progression of lesions in an experimental osteoarthritis (OA) dog model." | 3.70 | Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. ( Connor, JR; Currie, MG; Di Battista, JA; Fernandes, JC; Jovanovic, D; Manning, P; Martel-Pelletier, J; Pelletier, JP, 1998) |
| "In order to address the issue of the role of mast cells (MC) and nitric oxide (NO) in rheumatic synovial-fluid diseases, synovial fluid (SF) collected from the knee of patients with osteoarthritis (OA), articular chondrocalcinosis (ACC) or rheumatoid arthritis (RA) was examined for the levels of mast cells (MC), histamine, tryptase, phospholipase A2 and nitrite." | 3.69 | Cellular activation products in osteoarthritis synovial fluid. ( Florentin, J; Galoppin, L; Hilliquin, P; Menkes, CJ; Renoux, M, 1995) |
| "Epi-lupeol was identified as the principal constituent of B." | 1.36 | Boswellia frereana (frankincense) suppresses cytokine-induced matrix metalloproteinase expression and production of pro-inflammatory molecules in articular cartilage. ( Ali, AY; Blain, EJ; Duance, VC, 2010) |
| "To describe a method to study joint pain in experimental osteoarthritis (OA) and to study nitric oxide (NO) participation in experimental OA." | 1.33 | A quantitative approach to measure joint pain in experimental osteoarthritis--evidence of a role for nitric oxide. ( Castro, RR; Cunha, FQ; Rocha, FA; Silva, FS, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lo Monaco, M | 1 |
| Gervois, P | 1 |
| Beaumont, J | 1 |
| Clegg, P | 1 |
| Bronckaers, A | 1 |
| Vandeweerd, JM | 1 |
| Lambrichts, I | 1 |
| Ahmad, N | 1 |
| Ansari, MY | 1 |
| Bano, S | 1 |
| Haqqi, TM | 2 |
| Xue, EX | 1 |
| Lin, JP | 1 |
| Zhang, Y | 1 |
| Sheng, SR | 1 |
| Liu, HX | 1 |
| Zhou, YL | 1 |
| Xu, H | 1 |
| Lee, SA | 1 |
| Moon, SM | 1 |
| Han, SH | 1 |
| Hwang, EJ | 1 |
| Park, BR | 1 |
| Kim, JS | 1 |
| Kim, DK | 1 |
| Kim, CS | 1 |
| Pei, Y | 1 |
| Cui, F | 1 |
| Du, X | 1 |
| Shang, G | 1 |
| Xiao, W | 1 |
| Yang, X | 1 |
| Cui, Q | 1 |
| Balaganur, V | 1 |
| Pathak, NN | 1 |
| Lingaraju, MC | 1 |
| More, AS | 1 |
| Latief, N | 1 |
| Kumari, RR | 1 |
| Kumar, D | 1 |
| Tandan, SK | 1 |
| Yeh, CC | 1 |
| Su, YH | 1 |
| Lin, YJ | 1 |
| Chen, PJ | 1 |
| Shi, CS | 1 |
| Chen, CN | 1 |
| Chang, HI | 1 |
| Feelisch, M | 1 |
| Gosset, M | 1 |
| Berenbaum, F | 1 |
| Levy, A | 1 |
| Pigenet, A | 1 |
| Thirion, S | 1 |
| Cavadias, S | 1 |
| Jacques, C | 1 |
| Deffaud, J | 1 |
| Kirchmeyer, M | 1 |
| Domagala, F | 1 |
| Ficheux, H | 1 |
| Netter, P | 1 |
| Bianchi, A | 1 |
| Jouzeau, JY | 1 |
| Blain, EJ | 1 |
| Ali, AY | 1 |
| Duance, VC | 1 |
| Paino, IM | 1 |
| Miranda, JC | 1 |
| Marzocchi-Machado, CM | 1 |
| Cesarino, EJ | 1 |
| de Castro, FA | 1 |
| de Souza, AM | 1 |
| Akhtar, N | 1 |
| Griffiths, HR | 1 |
| Aldred, S | 1 |
| Dale, C | 1 |
| Nakano, E | 1 |
| Kitas, GD | 1 |
| Grant, MG | 1 |
| Nugent, D | 1 |
| Taiwo, FA | 1 |
| Li, L | 1 |
| Powers, HJ | 1 |
| Castro, RR | 1 |
| Cunha, FQ | 1 |
| Silva, FS | 1 |
| Rocha, FA | 1 |
| Renoux, M | 2 |
| Hilliquin, P | 3 |
| Galoppin, L | 2 |
| Florentin, J | 1 |
| Menkes, CJ | 2 |
| Florentin, I | 1 |
| Pelletier, JP | 1 |
| Jovanovic, D | 1 |
| Fernandes, JC | 1 |
| Manning, P | 1 |
| Connor, JR | 1 |
| Currie, MG | 1 |
| Di Battista, JA | 1 |
| Martel-Pelletier, J | 1 |
| Takahashi, T | 1 |
| Kondoh, T | 1 |
| Ohtani, M | 1 |
| Homma, H | 1 |
| Fukuda, M | 1 |
| Spreng, D | 1 |
| Sigrist, N | 1 |
| Jungi, T | 1 |
| Busato, A | 1 |
| Lang, J | 1 |
| Pfister, H | 1 |
| Schawalder, P | 1 |
| Borderie, D | 2 |
| Le Marechal, H | 1 |
| Ekindjian, OG | 2 |
| Hernvann, A | 2 |
| Studer, RK | 1 |
| Levicoff, E | 1 |
| Georgescu, H | 1 |
| Miller, L | 1 |
| Jaffurs, D | 1 |
| Evans, CH | 1 |
| Lemarchal, H | 1 |
| Kahan, A | 1 |
| Ersoy, Y | 1 |
| Ozerol, E | 1 |
| Baysal, O | 1 |
| Temel, I | 1 |
| MacWalter, RS | 1 |
| Meral, U | 1 |
| Altay, ZE | 1 |
| Farrell, AJ | 1 |
| Blake, DR | 1 |
| Palmer, RM | 1 |
| Moncada, S | 1 |
25 other studies available for nitrites and Osteoarthritis
| Article | Year |
|---|---|
Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis.
Topics: Adolescent; Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Chondrocytes; Chondrog | 2020 |
Imperatorin suppresses IL-1β-induced iNOS expression via inhibiting ERK-MAPK/AP1 signaling in primary human OA chondrocytes.
Topics: Anti-Inflammatory Agents; Cartilage; Cell Survival; Chondrocytes; Extracellular Signal-Regulated MAP | 2020 |
Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway.
Topics: Animals; Cartilage; Cell Survival; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Immunohistochemi | 2017 |
Chondroprotective effects of aqueous extract of Anthriscus sylvestris leaves on osteoarthritis in vitro and in vivo through MAPKs and NF-κB signaling inhibition.
Topics: Animals; Apiaceae; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Cyclooxygenas | 2018 |
Antioxidative nanofullerol inhibits macrophage activation and development of osteoarthritis in rats.
Topics: Animals; Antioxidants; Cells, Cultured; Female; Fullerenes; Interleukin-1beta; Interleukin-6; Joints | 2019 |
Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Chondrocytes; Cytokines; Enzyme Inhibitors; | 2014 |
Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis.
Topics: Alkaline Phosphatase; Animals; Biological Availability; Bone and Bones; Cell Differentiation; Cell P | 2015 |
The chemical biology of nitric oxide--an outsider's reflections about its role in osteoarthritis.
Topics: Disease Progression; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Osteoarthritis | 2008 |
Mechanical stress and prostaglandin E2 synthesis in cartilage.
Topics: Animals; Cartilage; Cell Culture Techniques; Cell Survival; Cyclooxygenase 2; Dinoprostone; Hydroxyp | 2008 |
Modulatory effect of rhein on IL-1alpha-induced responses in human chondrocytes: a comparative study between antibody microarrays and specific ELISAs.
Topics: Anthraquinones; Antibodies; Cartilage, Articular; Chemokines; Chondrocytes; Cytokines; Enzyme-Linked | 2008 |
Boswellia frereana (frankincense) suppresses cytokine-induced matrix metalloproteinase expression and production of pro-inflammatory molecules in articular cartilage.
Topics: Animals; Anti-Inflammatory Agents; Boswellia; Cartilage, Articular; Cattle; Cell Survival; Chondrocy | 2010 |
Phagocytosis and nitric oxide levels in rheumatic inflammatory states in elderly women.
Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Female; Humans; Inflammation Mediators; Leukocyte Coun | 2011 |
Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.
Topics: Aged; Antioxidants; Catechin; Chondrocytes; Cytoprotection; Drug Interactions; Gene Expression; Huma | 2011 |
Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blotting, Western; Cardiovascular Diseases; Case-Control Studies | 2006 |
A quantitative approach to measure joint pain in experimental osteoarthritis--evidence of a role for nitric oxide.
Topics: Amidines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Benzylamines; Ex | 2006 |
Cellular activation products in osteoarthritis synovial fluid.
Topics: Aged; Arthritis, Rheumatoid; Cell Count; Chondrocalcinosis; Chymases; Female; Histamine; Humans; Inf | 1995 |
Release of mast cell mediators and nitrites into knee joint fluid in osteoarthritis--comparison with articular chondrocalcinosis and rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cell Count; Chondrocalcinosis; Chymases; Colorimetry; Female; Histamine | 1996 |
Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dinoprostone; Dogs; Enzyme Inhibitors; | 1998 |
Association between arthroscopic diagnosis of temporomandibular joint osteoarthritis and synovial fluid nitric oxide levels.
Topics: Adult; Aged; Arthroscopy; Cartilage, Articular; Endoscopy; Female; Free Radical Scavengers; Humans; | 1999 |
Nitric oxide metabolite production in the cranial cruciate ligament, synovial membrane, and articular cartilage of dogs with cranial cruciate ligament rupture.
Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Cartilage, Articular; Dog | 2000 |
Nitric oxide modifies glycolytic pathways in cultured human synoviocytes.
Topics: Cell Survival; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glyceraldeh | 2000 |
Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Huma | 2000 |
Tetracyclines inhibit nitrosothiol production by cytokine-stimulated osteoarthritic synovial cells.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Survi | 2001 |
Serum nitrate and nitrite levels in patients with rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Case-Control Studies; Female; Humans | 2002 |
Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases.
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitrites; Osteoarthritis; Rh | 1992 |