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nitrites and Neurodegenerative Diseases

nitrites has been researched along with Neurodegenerative Diseases in 16 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Myeloperoxidase (MPO) and MPO-catalyzed hypochlorous acid (HOCl) is elevated in many neurodegenerative diseases, and lead to severe tissue injuries."3.83Inhibition of myeloperoxidase-mediated oxidative damage by nitrite in SH-SY5Y cells: Relevance to neuroprotection in neurodegenerative diseases. ( Ding, Y; Lu, N; Peng, YY; Tian, R, 2016)
"Nitric oxide metabolites, nitrates, and nitrites (NNx), were measured in the cerebrospinal fluid (CSF) of children with PEHO syndrome or PEHO-like syndrome, and in controls with other neurologic diseases."3.70Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome). ( Riikonen, R; Vanhatalo, S, 2000)
"Boron is a metalloid which is present in food in small amounts and is suggested here to inhibit apoptosis by stabilizing the mitochondrial membrane structure, thus preventing matrix remodeling and the release of cytochrome c, an apoptosis-inducer protein from the mitochondrion."1.51Boron inhibits apoptosis in hyperapoptosis condition: Acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling. ( Ali, S; Routray, I, 2019)
" Quercetin (QC) in combination with piperine (bioenhancer) acts as potential antioxidant, anti-inflammatory and neuroprotective against 6-OHDA rat model of PD."1.48Piperine in combination with quercetin halt 6-OHDA induced neurodegeneration in experimental rats: Biochemical and neurochemical evidences. ( Kumar, P; Singh, S, 2018)
"Hypercapnia is regularly observed in chronic lung disease, such as bronchopulmonary dysplasia in preterm infants."1.36Sustained hypercapnia induces cerebral microvascular degeneration in the immature brain through induction of nitrative stress. ( Balazy, M; Chemtob, S; Hamel, D; Hardy, P; Honoré, JC; Hou, X; Jankov, RP; Kooli, A; Mancini, JA; Picard, E; Rivera, JC; Tremblay, S; Varma, DR, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (56.25)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, S2
Kumar, P1
Routray, I1
Ali, S1
Yadav, S1
Appukuttan, JP1
Troška, P1
Chudoba, R1
Danč, L1
Bodor, R1
Horčičiak, M1
Tesařová, E1
Masár, M1
Pérez Del Palacio, J1
Díaz, C1
de la Cruz, M1
Annang, F1
Martín, J1
Pérez-Victoria, I1
González-Menéndez, V1
de Pedro, N1
Tormo, JR1
Algieri, F1
Rodriguez-Nogales, A1
Rodríguez-Cabezas, ME1
Reyes, F1
Genilloud, O1
Vicente, F1
Gálvez, J1
Lu, N1
Ding, Y1
Tian, R1
Peng, YY1
Honoré, JC1
Kooli, A1
Hou, X1
Hamel, D1
Rivera, JC1
Picard, E1
Hardy, P1
Tremblay, S1
Varma, DR1
Jankov, RP1
Mancini, JA1
Balazy, M1
Chemtob, S1
Hyun, DH1
Gray, DA1
Halliwell, B1
Jenner, P1
Dheen, ST1
Jun, Y1
Yan, Z1
Tay, SS1
Ling, EA1
Luna-Medina, R1
Cortes-Canteli, M1
Alonso, M1
Santos, A1
Martínez, A1
Perez-Castillo, A1
Minghetti, L2
Ajmone-Cat, MA2
De Berardinis, MA1
De Simone, R1
Scumpia, PO1
Kelly, KM1
Reeves, WH1
Stevens, BR1
Das, T1
Ravindran, A1
Chaturvedi, RK1
Shukla, Y1
Agarwal, AK1
Dikshit, M1
Kinsner, A1
Pilotto, V1
Deininger, S1
Brown, GC1
Coecke, S1
Hartung, T1
Bal-Price, A1
Vanhatalo, S1
Riikonen, R1
Nicolini, A1

Reviews

1 review available for nitrites and Neurodegenerative Diseases

ArticleYear
Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation.
    Brain research. Brain research reviews, 2005, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; Chronic Disease; Coculture Techniques; Dinoprostone; Humans; Microglia; Neurodeg

2005

Other Studies

15 other studies available for nitrites and Neurodegenerative Diseases

ArticleYear
Piperine in combination with quercetin halt 6-OHDA induced neurodegeneration in experimental rats: Biochemical and neurochemical evidences.
    Neuroscience research, 2018, Volume: 133

    Topics: Alkaloids; Animals; Benzodioxoles; Brain Chemistry; Disease Models, Animal; Dose-Response Relationsh

2018
Boron inhibits apoptosis in hyperapoptosis condition: Acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling.
    Biochimica et biophysica acta. General subjects, 2019, Volume: 1863, Issue:1

    Topics: Apoptosis; Boron; Caspase 3; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Damage; Humans; In

2019
Inhibition of LPS induced neurochemical imbalance and oxidative stress by pigmented and non-pigmented rice bran extracts.
    Journal of food biochemistry, 2019, Volume: 43, Issue:3

    Topics: Animals; Dopamine; Humans; Lipopolysaccharides; Male; Malondialdehyde; Neurodegenerative Diseases; N

2019
Determination of nitrite and nitrate in cerebrospinal fluid by microchip electrophoresis with microsolid phase extraction pre-treatment.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jul-01, Volume: 930

    Topics: Adolescent; Adult; Biomarkers; Electrophoresis, Microchip; Female; Humans; Limit of Detection; Linea

2013
High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries.
    Journal of biomolecular screening, 2016, Volume: 21, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Caco-2 Cells; Central Nervous System; Comple

2016
Inhibition of myeloperoxidase-mediated oxidative damage by nitrite in SH-SY5Y cells: Relevance to neuroprotection in neurodegenerative diseases.
    European journal of pharmacology, 2016, Jun-05, Volume: 780

    Topics: Biocatalysis; Cell Line, Tumor; Humans; Hypochlorous Acid; Neurodegenerative Diseases; Neurons; Neur

2016
Sustained hypercapnia induces cerebral microvascular degeneration in the immature brain through induction of nitrative stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Hypercapnia; Neurodegenerative Diseases; Nitrates; Nitric Oxide Sy

2010
Interference with ubiquitination causes oxidative damage and increased protein nitration: implications for neurodegenerative diseases.
    Journal of neurochemistry, 2004, Volume: 90, Issue:2

    Topics: Aldehydes; Antioxidants; Cell Division; Cell Line; Cell Survival; Clone Cells; Cysteine Endopeptidas

2004
Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia.
    Glia, 2005, Apr-01, Volume: 50, Issue:1

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Inflammation Mediators;

2005
Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Alitretinoin; Anilides; Animals; Anti-Inflammatory Agents; Apoptosis; Astrocytes; Brain; Cell Death;

2005
Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes.
    Glia, 2005, Nov-01, Volume: 52, Issue:2

    Topics: Animals; Antibodies, Blocking; Antiviral Agents; Astrocytes; Blotting, Western; Cell Survival; Enzym

2005
Involvement of nitric oxide in neurodegeneration: a study on the experimental models of Parkinson's disease.
    Redox report : communications in free radical research, 2005, Volume: 10, Issue:2

    Topics: Animals; Brain; Female; Lipopolysaccharides; Male; Neurodegenerative Diseases; NG-Nitroarginine Meth

2005
Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation.
    Journal of neurochemistry, 2005, Volume: 95, Issue:4

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Analysis of Variance; Animals; Animals, Newborn; Caspases; Cell D

2005
Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome).
    Epilepsia, 2000, Volume: 41, Issue:6

    Topics: Adolescent; Age Factors; Atrophy; Brain; Child; Child, Preschool; Humans; Infant; Neurodegenerative

2000
Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.
    Journal of neuroscience research, 2001, Nov-15, Volume: 66, Issue:4

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Survival; Cells, Cul

2001