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nitrites and Nerve Degeneration

nitrites has been researched along with Nerve Degeneration in 32 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether nitric oxide (NO) plays a role in degenerative neurologic disease (DND), we measured nitrite, nitrate and cyclic GMP in cerebrospinal fluid (CSF) samples from patients with Parkinson's disease (PD), spinocerebellar ataxia (SCA) and amyotrophic lateral sclerosis (ALS)."3.69Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases. ( Ikeda, M; Miyatake, T; Murota, S; Sato, I; Yuasa, T, 1995)
"The study was conducted to evaluate the effect of minocycline against pesticide rotenone induced adverse effects in different rat brain regions."1.48Minocycline diminishes the rotenone induced neurotoxicity and glial activation via suppression of apoptosis, nitrite levels and oxidative stress. ( Biswas, J; Gupta, P; Gupta, S; Singh, A; Singh, DK; Singh, S; Verma, DK, 2018)
" Acute and chronic administration of 1% or 2."1.33Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain. ( Ahmadiani, A; Hassanzadeh, P, 2006)
"Quisqualic acid was injected into the right nucleus basalis of rats."1.31Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease. ( Casamenti, F; Pepeu, G; Prosperi, C; Scali, C; Vannucchi, MG, 2000)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.50)18.2507
2000's18 (56.25)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verma, DK1
Singh, DK1
Gupta, S1
Gupta, P1
Singh, A2
Biswas, J1
Singh, S2
Jayaraj, RL1
Beiram, R1
Azimullah, S1
Meeran, MFN1
Ojha, SK1
Adem, A1
Jalal, FY1
Tegenge, MA1
Rajbhandari, L1
Shrestha, S1
Mithal, A1
Hosmane, S1
Venkatesan, A1
Tripathi, P1
Prakash, O1
Singh, MP1
Pérez Del Palacio, J1
Díaz, C1
de la Cruz, M1
Annang, F1
Martín, J1
Pérez-Victoria, I1
González-Menéndez, V1
de Pedro, N1
Tormo, JR1
Algieri, F1
Rodriguez-Nogales, A1
Rodríguez-Cabezas, ME1
Reyes, F1
Genilloud, O1
Vicente, F1
Gálvez, J1
Singh, BK1
Kumar, V1
Chauhan, AK1
Dwivedi, A1
Kumar, A1
Singh, D1
Patel, DK1
Ray, RS1
Jain, SK1
Singh, C1
Armagan, G1
Kanit, L1
Terek, CM1
Sozmen, EY1
Yalcin, A1
Moon, M1
Kim, HG1
Hwang, L1
Seo, JH1
Kim, S2
Hwang, S1
Lee, D1
Chung, H1
Oh, MS1
Lee, KT1
Park, S1
Militão, GC1
Ferreira, PM1
de Freitas, RM1
Nobre, HV1
Cunha, GM1
de Vasconcelos, LM1
Magalhães, HI1
Oliveira Neto, RN1
Maia, FD1
de Moraes, MO1
Leal, LK1
Viana, GS1
Manukhina, EB3
Goriacheva, AV1
Barskov, IV3
Viktorov, IV3
Guseva, AA2
Pshennikova, MG3
Khomenko, IP2
Mashina, SIu1
Pokidyshev, DA2
Malyshev, IIu1
Goryacheva, AV2
Mashina, SY1
Malyshev, IY2
Kruglov, SV1
Smirin, BV1
Downey, HF1
Ramsaransing, GS1
Teelken, A1
Arutjunyan, AV1
De Keyser, J1
Li, G1
Cui, G1
Tzeng, NS1
Wei, SJ1
Wang, T2
Block, ML2
Hong, JS4
Zhang, W2
Pei, Z1
Miller, DS1
Wu, X1
Wilson, B1
Zhou, Y1
Zhang, J1
Hassanzadeh, P1
Ahmadiani, A1
Al-Majed, AA1
Sayed-Ahmed, MM1
Al-Omar, FA1
Al-Yahya, AA1
Aleisa, AM1
Al-Shabanah, OA1
Kumral, A2
Yesilirmak, DC2
Sonmez, U1
Baskin, H2
Tugyan, K2
Yilmaz, O2
Genc, S1
Gokmen, N1
Genc, K1
Duman, N2
Ozkan, H2
Qian, L1
Flood, PM1
Cantarella, G1
Lempereur, L1
D'Alcamo, MA1
Risuglia, N1
Cardile, V1
Pennisi, G1
Scoto, GM1
Bernardini, R1
Hwang, WS1
Chen, SH1
Lin, CH1
Chang, HK1
Chen, WC1
Lin, MT1
Cilaker, S1
Dawson, VL1
Brahmbhatt, HP1
Mong, JA1
Dawson, TM1
Kuiper, MA1
Visser, JJ1
Bergmans, PL1
Scheltens, P1
Wolters, EC1
Ikeda, M1
Sato, I1
Yuasa, T1
Miyatake, T1
Murota, S1
Palumbo, A1
Napolitano, A1
Barone, P1
d'Ischia, M1
Taskiran, D1
Sagduyu, A1
Yüceyar, N1
Kutay, FZ1
Pögün, S1
Scali, C1
Prosperi, C1
Vannucchi, MG1
Pepeu, G1
Casamenti, F1
Fassbender, K1
Fatar, M1
Ragoschke, A1
Picard, M1
Bertsch, T1
Kuehl, S1
Hennerici, M1
Liu, B1
Qin, L1
Yang, SN1
Wilson, BC1
Liu, Y1
Stoffel, M1
Rinecker, M1
Graf, R1
Baethmann, A1
Plesnila, N1

Other Studies

32 other studies available for nitrites and Nerve Degeneration

ArticleYear
Minocycline diminishes the rotenone induced neurotoxicity and glial activation via suppression of apoptosis, nitrite levels and oxidative stress.
    Neurotoxicology, 2018, Volume: 65

    Topics: Animals; Apoptosis; Astrocytes; Brain; Caspase 3; CD11b Antigen; DNA Fragmentation; Glutathione; Lip

2018
Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease.
    Molecules (Basel, Switzerland), 2019, Jun-10, Volume: 24, Issue:11

    Topics: alpha-Synuclein; Animals; Antioxidants; Brain; Catalase; Cyclooxygenase 2; Cytokines; Disease Models

2019
Curcumin protects axons from degeneration in the setting of local neuroinflammation.
    Experimental neurology, 2014, Volume: 253

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axons; Cells, Cultured; Coculture Techniques; Curc

2014
Ibuprofen abates cypermethrin-induced expression of pro-inflammatory mediators and mitogen-activated protein kinases and averts the nigrostriatal dopaminergic neurodegeneration.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Behavior, Animal; Dopamine; Dopaminergic Neurons; Ibuprofen; Inflammation Mediators; Lipid

2016
High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries.
    Journal of biomolecular screening, 2016, Volume: 21, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Caco-2 Cells; Central Nervous System; Comple

2016
Neuronal Nitric Oxide Synthase Negatively Regulates Zinc-Induced Nigrostriatal Dopaminergic Neurodegeneration.
    Molecular neurobiology, 2017, Volume: 54, Issue:4

    Topics: Animals; Behavior, Animal; Blotting, Western; Caspase 3; Cell Survival; Cytochromes c; Dopaminergic

2017
The levels of glutathione and nitrite-nitrate and the expression of Bcl-2 mRNA in ovariectomized rats treated by raloxifene against kainic acid.
    The International journal of neuroscience, 2009, Volume: 119, Issue:2

    Topics: Animals; Apoptosis; Disease Models, Animal; Female; Glutathione; Kainic Acid; Nerve Degeneration; Ne

2009
Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation.
    Neurotoxicity research, 2009, Volume: 15, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Animals, Newborn; Cells

2009
Effects of lipoic acid on oxidative stress in rat striatum after pilocarpine-induced seizures.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: Animals; Antioxidants; Catalase; Convulsants; Corpus Striatum; Disease Models, Animal; Drug Interact

2010
Caffeine and CSC, adenosine A2A antagonists, offer neuroprotection against 6-OHDA-induced neurotoxicity in rat mesencephalic cells.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Animals; Apoptosis; Caffeine; Cells, Cultured; Encephalitis; Female;

2010
[Prevention of the brain neurodegeneration in rats with experimental Alzheimer's disease by adaptation to hypoxia].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2009, Volume: 95, Issue:7

    Topics: Adaptation, Physiological; Alzheimer Disease; Amyloid beta-Peptides; Animals; Hypoxia; Lipid Peroxid

2009
Prevention of neurodegenerative damage to the brain in rats in experimental Alzheimer's disease by adaptation to hypoxia.
    Neuroscience and behavioral physiology, 2010, Volume: 40, Issue:7

    Topics: Adaptation, Physiological; Alzheimer Disease; Amyloid beta-Peptides; Animals; Hypoxia; Lipid Peroxid

2010
Adaptation to intermittent hypoxia restricts nitric oxide overproduction and prevents beta-amyloid toxicity in rat brain.
    Nitric oxide : biology and chemistry, 2010, Dec-15, Volume: 23, Issue:4

    Topics: Adaptation, Physiological; Amyloid beta-Peptides; Animals; Brain; Hypoxia; Male; Nerve Degeneration;

2010
Peripheral blood leukocyte NO production in MS patients with a benign vs progressive course.
    Neurology, 2004, Jan-27, Volume: 62, Issue:2

    Topics: Adult; Axons; Female; Humans; Interleukin-12; Leukocytes; Male; Middle Aged; Multiple Sclerosis; Mul

2004
Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:6

    Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Coculture Techniques; Dextromethorphan; Dinoprosto

2005
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:6

    Topics: alpha-Synuclein; Animals; Astrocytes; Brain; Cells, Cultured; Dinoprostone; Dopamine; Embryo, Mammal

2005
Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain.
    Synapse (New York, N.Y.), 2006, Volume: 59, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Immunohistochemistry; Inflammation; Irritan

2006
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:8

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Disease Models, Animal; Energy Metaboli

2006
Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic-ischemic brain injury in neonatal rats.
    Brain research, 2006, Oct-18, Volume: 1115, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Apoptosis; Asphyxia Neonatorum; Brain; Brain Infarction; Cerebral

2006
Role of microglia in inflammation-mediated degeneration of dopaminergic neurons: neuroprotective effect of interleukin 10.
    Journal of neural transmission. Supplementum, 2006, Issue:70

    Topics: Animals; Cytokines; Dopamine; Indicators and Reagents; Inflammation; Interleukin-10; Lipopolysacchar

2006
Trail interacts redundantly with nitric oxide in rat astrocytes: potential contribution to neurodegenerative processes.
    Journal of neuroimmunology, 2007, Volume: 182, Issue:1-2

    Topics: Animals; Antibodies; Apoptosis; Astrocytes; Cells, Cultured; Drug Interactions; Enzyme Activation; M

2007
Human umbilical cord blood-derived CD34+ cells can be used as a prophylactic agent for experimental heatstroke.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Animals; Antigens, CD34; Basal Ganglia; Cerebrovascular Disorders; Cord Blood Stem Cell Transplantat

2008
Effects of activated protein C on neonatal hypoxic ischemic brain injury.
    Brain research, 2008, May-19, Volume: 1210

    Topics: Animals; Animals, Newborn; Anticoagulants; Apoptosis; Brain; Carotid Stenosis; Dentate Gyrus; Diseas

2008
Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures.
    Neuropharmacology, 1994, Volume: 33, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Interferon-gamma; L

1994
Decreased cerebrospinal fluid nitrate levels in Parkinson's disease, Alzheimer's disease and multiple system atrophy patients.
    Journal of the neurological sciences, 1994, Volume: 121, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Dementia; Female; Humans; Male; Middle Aged; Nerve Degeneration; N

1994
Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases.
    Journal of neural transmission. General section, 1995, Volume: 100, Issue:3

    Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Cyclic GMP; Female; Humans; Male; Middle Aged; Nerv

1995
Nitrite- and peroxide-dependent oxidation pathways of dopamine: 6-nitrodopamine and 6-hydroxydopamine formation as potential contributory mechanisms of oxidative stress- and nitric oxide-induced neurotoxicity in neuronal degeneration.
    Chemical research in toxicology, 1999, Volume: 12, Issue:12

    Topics: Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Dopamine; Male; Nerve Degene

1999
Increased cerebrospinal fluid and serum nitrite and nitrate levels in amyotrophic lateral sclerosis.
    The International journal of neuroscience, 2000, Volume: 101, Issue:1-4

    Topics: Amyotrophic Lateral Sclerosis; Female; Glutamates; Humans; Male; Middle Aged; Nerve Degeneration; Ni

2000
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.
    The European journal of neuroscience, 2000, Volume: 12, Issue:6

    Topics: Acetylcholine; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline O-Acetyl

2000
Subacute but not acute generation of nitric oxide in focal cerebral ischemia.
    Stroke, 2000, Volume: 31, Issue:9

    Topics: Animals; Brain Ischemia; Corpus Striatum; Enzyme Inhibitors; Guanidines; Microdialysis; Nerve Degene

2000
Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:3

    Topics: Animals; Cells, Cultured; Dopamine; Dynorphins; Immunohistochemistry; Lipopolysaccharides; Mesenceph

2001
Nitric oxide in the penumbra of a focal cortical necrosis in rats.
    Neuroscience letters, 2002, May-24, Volume: 324, Issue:3

    Topics: Animals; Brain Injuries; Cerebral Cortex; Cold Temperature; Extracellular Space; Male; Microdialysis

2002