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nitrites and Muscle Relaxation

nitrites has been researched along with Muscle Relaxation in 44 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome."7.74Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008)
" We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome."3.74Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008)
" The increased activities of AS and AL suggest the increased and effective recycling of citrulline to arginine in excitotoxicity, making NO production more effective and contributing to its toxic effects."1.35Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain. ( Chandran, G; Sirajudeen, KN; Swamy, M, 2009)
"Proteinuria was within normal limits in all groups studied but L-arg caused a significant decrease in this parameter in both the RA8 and RA12 groups."1.31L-Arginine effects on blood pressure and renal function of intrauterine restricted rats. ( Alves, GM; Barão, MA; Brandizzi, LI; Franco Md, Mdo C; Laurindo, FR; Lucas, SR; Nascimento Gomes, G; Nigro, D; Odo, LN; Zaladek Gil, F, 2002)
"Luminal thrombus induces arterial dysfunction acutely without causing endothelial cell loss."1.31Luminal thrombus disrupts nitric oxide-dependent endothelial physiology. ( Chiou, A; Clouse, WD; Davis, MR; DeCaprio, JD; Hagino, RT; Kashyap, VS; Kerby, JD; Ortegon, DP, 2002)
"Experiments were designed to investigate the effects of chronic administration of an NO donor, (+/-)-(E)-ethyl-2-[(E)-ethylhydroxyimino]-5-nitro-3-hexeneamide (FK409), on the impairment of the acetylcholine-induced endothelium-dependent relaxations of the aorta, perfused mesenteric arterial bed and perfused kidney that seen in streptozotocin-induced diabetic rats."1.30Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat. ( Hayashi, T; Kamata, K, 1999)
"Pretreatment with phorone, a glutathione S-transferase substrate, depleted cellular glutathione and decreased nitrite production from GTN."1.28Metabolism of nitroglycerin by smooth muscle cells. Involvement of glutathione and glutathione S-transferase. ( Burk, RF; Hill, KE; Hoover, RL; Hunt, RW; Jones, R, 1992)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.36)18.7374
1990's14 (31.82)18.2507
2000's23 (52.27)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rocha, BS3
Gago, B3
Barbosa, RM3
Cavaleiro, C1
Laranjinha, J3
Pinder, AG1
Pittaway, E1
Morris, K1
James, PE1
Swamy, M1
Sirajudeen, KN1
Chandran, G1
Alves, GM1
Barão, MA1
Odo, LN1
Nascimento Gomes, G1
Franco Md, Mdo C1
Nigro, D1
Lucas, SR1
Laurindo, FR1
Brandizzi, LI1
Zaladek Gil, F1
Ismailoglu, UB1
Sahin-Erdemli, I1
Sungur, A1
Ilhan, M1
Orshal, JM1
Khalil, RA1
Taniguchi, J1
Honda, H1
Shibusawa, Y1
Iwata, T1
Notoya, Y1
Jiménez-Altayó, F1
Briones, AM1
Giraldo, J1
Planas, AM1
Salaices, M1
Vila, E1
Pinna, C1
Bolego, C1
Sanvito, P1
Pelosi, V1
Baetta, R1
Corsini, A1
Gaion, RM1
Cignarella, A1
Ushiyama, M1
Kuramochi, T1
Katayama, S1
Shah, DI1
Singh, M1
Zhang, LF1
Peng, SQ1
Wang, S1
Li, BL1
Han, G1
Dong, YS1
Manning, JJ1
Wirz, AA1
McColl, KE1
Matsuzaki, G1
Ishizaka, N1
Furuta, K1
Hongo, M1
Saito, K1
Sakurai, R1
Koike, K1
Nagai, R2
Jia, Y1
Xu, L1
Heisler, S1
Martin, JG1
Ferioli, R1
Folco, GC1
Ferretti, C1
Gasco, AM1
Medana, C1
Fruttero, R1
Civelli, M1
Gasco, A1
Chung, BH1
Chang, KC1
Kita, Y1
Hirasawa, Y1
Kato, Y1
Ohkubo, K1
Ohno, M1
Nishino, S1
Kato, M1
Fukuyama, S1
Castillo, C1
Reyes, G1
Escalante, B1
López, P1
Castillo, EF1
Saito, Y1
Yamagishi, T1
Nakamura, T1
Ohyama, Y1
Aizawa, H1
Suga, T1
Matsumura, Y1
Masuda, H1
Kurabayashi, M1
Kuro-o, M1
Nabeshima, Y1
Kamata, K1
Hayashi, T2
Goto, H1
Shimada, Y1
Tanigawa, K1
Sekiya, N1
Shintani, T1
Terasawa, K1
Murohara, T1
Kugiyama, K1
Ota, Y1
Doi, H1
Ogata, N1
Ohgushi, M1
Yasue, H1
Figueroa, R1
Martinez, E1
Fayngersh, RP1
Tejani, N1
Mohazzab-H, KM1
Wolin, MS1
Manukhina, EB1
Smirin, BV1
Lyamina, NP1
Senchikhin, VN1
Vanin, AF2
Jayachandran, M1
Sumi, D1
Thakur, NK1
Esaki, T1
Muto, E1
Kano, H1
Asai, Y1
Iguchi, A1
Seshita, H1
Yoshida, M1
Takahashi, W1
Inadome, A1
Yono, M1
Miyamoto, Y1
Murakami, S1
Ueda, S1
Buyukafsar, K1
Nelli, S2
Martin, W3
Dick, JM1
Van Molle, W1
Libert, C1
Lefebvre, RA1
Ellis, A1
Lu, H1
Li, CG1
Rand, MJ1
Shahidullah, M1
Duncan, A1
Strachan, PD1
Rafique, KM1
Ball, SL1
McPate, MJ1
Davis, MR1
Ortegon, DP1
Clouse, WD1
Kerby, JD1
DeCaprio, JD1
Chiou, A1
Hagino, RT1
Kashyap, VS1
O'Donnell, JP1
Azzaro, AJ1
Urquilla, PR1
Dave, KC1
Jindal, MN1
Kelkar, VV1
Trivedi, HD1
Vedernikov, YP1
Mordvintcev, PI1
Malenkova, IV1
Hill, KE1
Hunt, RW1
Jones, R1
Hoover, RL1
Burk, RF1
Kowaluk, EA1
Fung, HL1
Wigilius, IM1
Axelsson, KL1
Andersson, RG1
Karlsson, JO1
Odman, S1
Wood, KS1
Buga, GM1
Byrns, RE1
Ignarro, LJ1
Stuehr, DJ1
Gross, SS1
Sakuma, I1
Levi, R1
Nathan, CF1
Smith, JA1
Lewis, MJ1
Henderson, AH1
Hayashi, S1
Park, MK1

Trials

1 trial available for nitrites and Muscle Relaxation

ArticleYear
Nitrogenous chemicals generated from acidification of saliva influence transient lower oesophageal sphincter relaxations.
    Scandinavian journal of gastroenterology, 2007, Volume: 42, Issue:12

    Topics: Ascorbic Acid; Double-Blind Method; Esophagogastric Junction; Female; Gastric Juice; Humans; Hydroge

2007

Other Studies

43 other studies available for nitrites and Muscle Relaxation

ArticleYear
Ethyl nitrite is produced in the human stomach from dietary nitrate and ethanol, releasing nitric oxide at physiological pH: potential impact on gastric motility.
    Free radical biology & medicine, 2015, Volume: 82

    Topics: Adult; Animals; Diet; Ethanol; Gastric Emptying; Gastric Mucosa; Humans; Lactuca; Muscle Relaxation;

2015
Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways.
    British journal of pharmacology, 2009, Volume: 157, Issue:8

    Topics: Animals; Aorta, Thoracic; Cell Hypoxia; Cyclooxygenase Inhibitors; Endothelium, Vascular; Guanylate

2009
Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation.
    Toxicology, 2009, Nov-09, Volume: 265, Issue:1-2

    Topics: Animals; Antioxidants; Catechin; Diet; Electrochemistry; Flavonoids; Food Analysis; Gastric Juice; G

2009
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic A

2009
Diffusion of nitric oxide through the gastric wall upon reduction of nitrite by red wine: physiological impact.
    Nitric oxide : biology and chemistry, 2010, Apr-01, Volume: 22, Issue:3

    Topics: Animals; Diffusion; Gastric Mucosa; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Ni

2010
L-Arginine effects on blood pressure and renal function of intrauterine restricted rats.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:10

    Topics: Animals; Arginine; Blood Pressure; Female; Food Deprivation; Glomerular Filtration Rate; Kidney; Kid

2002
Effects of lipopolysaccharide on epithelium-dependent relaxation in coaxial bioassay.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Animals; Biological Factors; Bronchoalveolar Lavage Fluid; Cell Count; Epithelium; Guinea Pigs; Inje

2004
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Est

2004
Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia.
    Vascular pharmacology, 2005, Volume: 43, Issue:1

    Topics: Acetylcholine; Animals; Biological Factors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhib

2005
Increased superoxide anion production by interleukin-1beta impairs nitric oxide-mediated relaxation in resistance arteries.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:1

    Topics: Animals; Arteries; Blotting, Western; Endothelium, Vascular; Fluorescent Antibody Technique; Interle

2006
Raloxifene elicits combined rapid vasorelaxation and long-term anti-inflammatory actions in rat aorta.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Blotting, Western; Cell Survival; Estradiol; Est

2006
Treatment with hypotensive agents affects the impaired relaxation of the penile corpus cavernosum in hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:7

    Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carbon Monoxide; Cyclic GMP; Electric

2006
Effect of demethylasterriquinone b1 in hypertension associated vascular endothelial dysfunction.
    International journal of cardiology, 2007, Sep-03, Volume: 120, Issue:3

    Topics: Animals; Aorta, Thoracic; Atorvastatin; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutary

2007
Direct effects of lead (Pb2+) on the relaxation of in vitro cultured rat aorta to acetylcholine.
    Toxicology letters, 2007, Apr-25, Volume: 170, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Drug Combinations; Male; Muscle Relaxation; Muscle, Smooth,

2007
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium

2008
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1

    Topics: Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction

1995
A new class of furoxan derivatives as NO donors: mechanism of action and biological activity.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: Animals; Aorta; Blood Platelets; Dose-Response Relationship, Drug; Guanylate Cyclase; Hemoglobins; H

1995
Photo-induced adequate nitric oxide (PIANO)-mediated relaxation in isolated rabbit corpus cavernosum.
    General pharmacology, 1994, Volume: 25, Issue:5

    Topics: Animals; Arginine; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; NG-Nitroarginine Me

1994
Comparison of hemodynamic effects of nitric oxide (NO) donors with different NO-releasing properties in rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:2

    Topics: Animals; Blood Pressure; Enzyme Inhibitors; Hematocrit; Hemodynamics; In Vitro Techniques; Isosorbid

1997
Endothelium-dependent vasodilatation in rat aorta is mainly mediated by nitric oxide.
    Proceedings of the Western Pharmacology Society, 1997, Volume: 40

    Topics: Animals; Aorta, Thoracic; Biological Factors; Endothelium, Vascular; Epoprostenol; In Vitro Techniqu

1997
Klotho protein protects against endothelial dysfunction.
    Biochemical and biophysical research communications, 1998, Jul-20, Volume: 248, Issue:2

    Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Cardiovascular System; Disease Models, Animal; Endo

1998
Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat.
    Research communications in molecular pathology and pharmacology, 1999, Volume: 103, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In

1999
Effect of Uncariae ramulus et Uncus on endothelium in spontaneously hypertensive rats.
    The American journal of Chinese medicine, 1999, Volume: 27, Issue:3-4

    Topics: Acetylcholine; Animals; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Muscle Co

1999
Effects of atrial and brain natriuretic peptides on lysophosphatidylcholine-mediated endothelial dysfunction.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Cattle; Coronary Vessels

1999
Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:3

    Topics: Adolescent; Adult; Arachidonic Acid; Colforsin; Diabetes, Gestational; Female; Humans; Hydrogen Pero

2000
Role of nitric oxide in adaptation to hypoxia and adaptive defense.
    Physiological research, 2000, Volume: 49, Issue:1

    Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Hypo

2000
Physiological concentration of 17beta-estradiol retards the progression of severe atherosclerosis induced by a high-cholesterol diet plus balloon catheter injury: role of NO.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:6

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Catheterization; Cholesterol; Cholesterol, Dietary; Cyc

2000
Prejunctional alpha-adrenoceptors regulate nitrergic neurotransmission in the rabbit urethra.
    European journal of pharmacology, 2000, Jul-21, Volume: 400, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug;

2000
Formation of nitric oxide from nitroxyl anion: role of quinones and ferricytochrome c.
    British journal of pharmacology, 2001, Volume: 132, Issue:1

    Topics: Animals; Aorta, Thoracic; Cytochrome c Group; Electron Transport Complex III; In Vitro Techniques; M

2001
Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Amidines; Animals; Arginine; Benzylamines; Carbachol; Cell Size; DNA, Antisense; Enzyme Inhibitors;

2001
Effects of agents that inactivate free radical NO (NO*) on nitroxyl anion-mediated relaxations, and on the detection of NO* released from the nitroxyl anion donor Angeli's salt.
    British journal of pharmacology, 2001, Volume: 134, Issue:3

    Topics: Animals; Antioxidants; Aorta, Thoracic; Benzoates; Free Radicals; Hematinics; Hydroxocobalamin; Imid

2001
Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide.
    European journal of pharmacology, 2002, Jan-18, Volume: 435, Issue:1

    Topics: Amitrole; Animals; Aorta; Catalase; Cattle; Cyanamide; Electrochemistry; Enzyme Inhibitors; Hemoglob

2002
Luminal thrombus disrupts nitric oxide-dependent endothelial physiology.
    The Journal of surgical research, 2002, May-15, Volume: 104, Issue:2

    Topics: Acetylcholine; Animals; Endothelium, Vascular; Factor VIII; Female; Femoral Artery; Iliac Artery; Im

2002
(3,4-Dihydroxybenzyl)-2-imidazoline (DHBI): an analogue of dopamine.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 26, Issue:2

    Topics: Adenylyl Cyclases; Animals; Arteries; Catechols; Corpus Striatum; Cyclic AMP; Imidazoles; In Vitro T

1979
Characterization of ultraviolet light-induced relaxation of the isolated duodenum of the rat.
    British journal of pharmacology, 1979, Volume: 66, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Duodenum; Kinetics; Muscle Contraction; Muscle Relaxation

1979
Effect of diethyldithiocarbamate on the activity of nitric oxide-releasing vasodilators.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Acetylcholine; Animals; Aorta; Cysteine; Ditiocarb; Male; Muscle Relaxation; Muscle, Smooth, Vascula

1992
Metabolism of nitroglycerin by smooth muscle cells. Involvement of glutathione and glutathione S-transferase.
    Biochemical pharmacology, 1992, Feb-04, Volume: 43, Issue:3

    Topics: Animals; Glutathione; Glutathione Transferase; Indocyanine Green; Ketones; Muscle Relaxation; Muscle

1992
Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Amyl Nitrite; Animals; Cattle; Coronary Vessels; Cysteine; Cytosol; Hot Temperature; In Vitro Techni

1991
Effects of sodium nitrite on ultraviolet light-induced relaxation and ultraviolet light-dependent activation of guanylate cyclase in bovine mesenteric arteries.
    Biochemical and biophysical research communications, 1990, May-31, Volume: 169, Issue:1

    Topics: Animals; Cattle; Enzyme Activation; Guanylate Cyclase; Mesenteric Arteries; Muscle Relaxation; Muscl

1990
Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide.
    Biochemical and biophysical research communications, 1990, Jul-16, Volume: 170, Issue:1

    Topics: Animals; Biological Assay; Cattle; Cyclic GMP; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric O

1990
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.
    The Journal of experimental medicine, 1989, Mar-01, Volume: 169, Issue:3

    Topics: Animals; Aorta; Arginine; Biological Assay; Biological Factors; Chemical Phenomena; Chemistry; Endot

1989
Evidence that inhibitory factor extracted from bovine retractor penis is nitrite, whose acid-activated derivative is stabilized nitric oxide.
    British journal of pharmacology, 1988, Volume: 93, Issue:3

    Topics: Animals; Aorta; Biological Products; Biotransformation; Cattle; Hydrogen-Ion Concentration; Male; Mu

1988
Increased susceptibility of newborn puppy mesenteric arteries to ouabain and reduced extracellular K+ concentration.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:2

    Topics: Animals; Animals, Newborn; Dinoprost; Dogs; Electric Stimulation; Extracellular Space; Female; In Vi

1987