nitrites has been researched along with Migraine Disorders in 18 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Watermelon ingestion triggered headache attacks in migraine patients and increased serum nitrite levels, attesting to a possible activation of the | 4.31 | Migraine Attacks Triggered by Ingestion of Watermelon. ( Araújo, NRA; Bezerra, GL; Lima, LKF; Lopes, LS; Pereira, SKS; Silva, SF; Silva-Néto, RP; Soares, AA, 2023) |
| "To test whether migraine and subarachnoid hemorrhage (SAH) are associated with increased sympathetic tone, we compared the neuropeptide Y-like (NPY-LI) and chromogranin A-like immunoreactivities (LI) of cerebrospinal fluid (CSF) from migraneurs and SAH patients with those from control subjects." | 3.70 | Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF. ( Donoso, MV; Huidobro-Toro, JP; Mellado, PA; Valenzuela, RF, 2000) |
| "To assess whether migraine patients display a chronic nitric oxide synthase (NOS) hyperactivity by comparing the nitric oxide (NO) production before and following a loading dose of L-arginine between migraine patients (interictally) and matched healthy control subjects." | 2.75 | No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers. ( de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH, 2010) |
| "Thirteen patients with migraine without aura and seven clinically healthy subjects (C) were selected." | 2.69 | Modulation of nitric oxide synthase by nitric oxide donor compounds in migraine. ( Cifone, MG; D'Alò, S; Giacovazzo, M; Martelletti, P; Rinaldi, C; Stirparo, G, 1998) |
| "Caffeine was the most common implicated trigger (28), followed by monosodium glutamate (25), cocoa (22), aspartame (13), cheese (13), citrus (10) and nitrites (six)." | 1.46 | Effect of exclusion of frequently consumed dietary triggers in a cohort of children with chronic primary headache. ( Taheri, S, 2017) |
| "The connection between migraine and cardiovascular diseases has also drawn attention to the endothelial dysfunctions and NO pathway abnormalities seen in patients with migraine." | 1.35 | Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period. ( Demir, M; Guldiken, B; Guldiken, S; Kabayel, L; Ozkan, H; Tugrul, A; Turgut, N, 2009) |
| "The molecular mechanisms of migraine have not been fully clarified yet." | 1.34 | Increased nitrosative and oxidative stress in platelets of migraine patients. ( Coskun, O; Inan, LE; Sürer, H; Yilmaz, G; Yücel, D, 2007) |
| "A total of 35 consecutive migraine patients without aura who came to gastroenterology polyclinic with various complaints and diagnosed H." | 1.34 | Migraine, Helicobacter pylori, and oxidative stress. ( Adam, B; Ardiçoğlu, Y; Kargili, A; Tunca, A, 2007) |
| "Fifty migraineurs subjects and 25 healthy subjects matched by gender and age were included." | 1.34 | Endothelial function in patients with migraine during the interictal period. ( Flórez, M; Guzmán, JC; López-Jaramillo, P; Morillo, CA; Pradilla, G; Rueda-Clausen, CF; Silva, FA; Silva, SY; Vesga, B; Zarruk, JG, 2007) |
| "Thirty subjects suffering from migraine with and without aura and 20 healthy controls were investigated." | 1.32 | Urinary nitric oxide metabolites and lipid peroxidation by-products in migraine. ( Carolei, A; Ciancarelli, I; Di Massimo, C; Marini, C; Tozzi-Ciancarelli, MG, 2003) |
| "Patients with migraine with aura and patients without aura were included in the study." | 1.31 | Blood nitrite levels in patients with migraine during headache-free period. ( Barthwal, MK; Dikshit, M; Nag, D; Seth, PK; Shukla, R; Srimal, RC; Srivastava, N, 2001) |
| "A hundred migraine patients and 69 cluster headache patients in the interictal period, and 112 controls, were studied." | 1.31 | Increased plasma nitrites in migraine and cluster headache patients in interictal period: basal hyperactivity of L-arginine-NO pathway? ( Bussone, G; Carlin, A; Catania, A; D'Amico, D; Ferraris, A; Grazzi, L; Leone, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Silva-Néto, RP | 1 |
| Bezerra, GL | 1 |
| Araújo, NRA | 1 |
| Silva, SF | 1 |
| Pereira, SKS | 1 |
| Lima, LKF | 1 |
| Soares, AA | 1 |
| Lopes, LS | 1 |
| Taheri, S | 1 |
| Guldiken, B | 1 |
| Demir, M | 1 |
| Guldiken, S | 1 |
| Turgut, N | 1 |
| Ozkan, H | 1 |
| Kabayel, L | 1 |
| Tugrul, A | 1 |
| Gruber, HJ | 1 |
| Bernecker, C | 1 |
| Pailer, S | 1 |
| Fauler, G | 1 |
| Horejsi, R | 1 |
| Möller, R | 1 |
| Lechner, A | 1 |
| Fazekas, F | 1 |
| Truschnig-Wilders, M | 1 |
| Van der Schueren, BJ | 1 |
| Verbrugge, FH | 1 |
| Verbesselt, R | 1 |
| Van Hecken, A | 1 |
| Depré, M | 1 |
| de Hoon, JN | 1 |
| Ciancarelli, I | 1 |
| Tozzi-Ciancarelli, MG | 1 |
| Di Massimo, C | 1 |
| Marini, C | 1 |
| Carolei, A | 1 |
| GIUNTA, A | 2 |
| Sarchielli, P | 1 |
| Pini, LA | 1 |
| Coppola, F | 1 |
| Rossi, C | 1 |
| Baldi, A | 1 |
| Mancini, ML | 1 |
| Calabresi, P | 1 |
| Yilmaz, G | 1 |
| Sürer, H | 1 |
| Inan, LE | 1 |
| Coskun, O | 1 |
| Yücel, D | 1 |
| Tunca, A | 1 |
| Ardiçoğlu, Y | 1 |
| Kargili, A | 1 |
| Adam, B | 1 |
| Silva, FA | 1 |
| Rueda-Clausen, CF | 1 |
| Silva, SY | 1 |
| Zarruk, JG | 1 |
| Guzmán, JC | 1 |
| Morillo, CA | 1 |
| Vesga, B | 1 |
| Pradilla, G | 1 |
| Flórez, M | 1 |
| López-Jaramillo, P | 1 |
| Martelletti, P | 1 |
| D'Alò, S | 1 |
| Stirparo, G | 1 |
| Rinaldi, C | 1 |
| Cifone, MG | 1 |
| Giacovazzo, M | 1 |
| Shimomura, T | 1 |
| Murakami, F | 1 |
| Kotani, K | 1 |
| Ikawa, S | 1 |
| Kono, S | 1 |
| Valenzuela, RF | 1 |
| Donoso, MV | 1 |
| Mellado, PA | 1 |
| Huidobro-Toro, JP | 1 |
| Shukla, R | 1 |
| Barthwal, MK | 1 |
| Srivastava, N | 1 |
| Nag, D | 1 |
| Seth, PK | 1 |
| Srimal, RC | 1 |
| Dikshit, M | 1 |
| D'Amico, D | 1 |
| Ferraris, A | 1 |
| Leone, M | 1 |
| Catania, A | 1 |
| Carlin, A | 1 |
| Grazzi, L | 1 |
| Bussone, G | 1 |
| Nattero, G | 1 |
| Gastaldi, L | 1 |
| Gai, V | 1 |
| Piazza, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Peripheral Gene Expression of Endocannabinoid System Components in Episodic and Chronic Migraine Patients: a Pilot Study[NCT04324710] | 75 participants (Actual) | Observational | 2017-12-12 | Completed | |||
| Factors Associated With Migraine Refractoriness to Preventive Treatments: Psychological Aspects and Relationship With Components of the Endocannabinoid System[NCT05046119] | 80 participants (Anticipated) | Observational | 2021-09-15 | Not yet recruiting | |||
| A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838] | Phase 2 | 40 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitrites and Migraine Disorders
| Article | Year |
|---|---|
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; | 2010 |
Modulation of nitric oxide synthase by nitric oxide donor compounds in migraine.
Topics: Adult; Female; Humans; Isosorbide Dinitrate; Male; Migraine Disorders; Monocytes; Nitric Oxide; Nitr | 1998 |
16 other studies available for nitrites and Migraine Disorders
| Article | Year |
|---|---|
Migraine Attacks Triggered by Ingestion of Watermelon.
Topics: Adult; Arginine; Citrullus; Eating; Headache; Humans; Migraine Disorders; Nitric Oxide; Nitrites; Yo | 2023 |
Effect of exclusion of frequently consumed dietary triggers in a cohort of children with chronic primary headache.
Topics: Adolescent; Aspartame; Cacao; Caffeine; Cheese; Child; Child, Preschool; Chocolate; Citrus; Diet; Di | 2017 |
Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period.
Topics: Adult; Arginine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Migraine Diso | 2009 |
Hyperinsulinaemia in migraineurs is associated with nitric oxide stress.
Topics: Adult; Blood Glucose; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Humans; Hyperinsulinism; I | 2010 |
Urinary nitric oxide metabolites and lipid peroxidation by-products in migraine.
Topics: Adult; Brain; Endothelium, Vascular; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Migraine | 2003 |
[Nitrite compounds in the therapy of hemicrania].
Topics: Anencephaly; Headache; Humans; Migraine Disorders; Nitrites | 1961 |
[Nitro compounds in migraine therapy].
Topics: Humans; Migraine Disorders; Nitrites; Nitro Compounds | 1962 |
Endocannabinoids in chronic migraine: CSF findings suggest a system failure.
Topics: Adult; Amides; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; | 2007 |
Endocannabinoids in chronic migraine: CSF findings suggest a system failure.
Topics: Adult; Amides; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; | 2007 |
Endocannabinoids in chronic migraine: CSF findings suggest a system failure.
Topics: Adult; Amides; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; | 2007 |
Endocannabinoids in chronic migraine: CSF findings suggest a system failure.
Topics: Adult; Amides; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; | 2007 |
Increased nitrosative and oxidative stress in platelets of migraine patients.
Topics: Adult; Biomarkers; Blood Platelets; Female; Humans; Male; Malondialdehyde; Migraine Disorders; Nitra | 2007 |
Migraine, Helicobacter pylori, and oxidative stress.
Topics: Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Migraine Disorders; | 2007 |
Endothelial function in patients with migraine during the interictal period.
Topics: Adult; Blood Pressure; Case-Control Studies; Endothelium, Vascular; Female; Forearm; Humans; Male; M | 2007 |
Platelet nitric oxide metabolites in migraine.
Topics: Adult; Blood Platelets; Case-Control Studies; Cyclic GMP; Female; Humans; Male; Migraine Disorders; | 1999 |
Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF.
Topics: Adult; Biomarkers; Cerebrospinal Fluid Proteins; Chromogranin A; Chromogranins; Female; Humans; Male | 2000 |
Blood nitrite levels in patients with migraine during headache-free period.
Topics: Adult; Blood Platelets; Female; Humans; Male; Migraine Disorders; Neutrophils; Nitrites; Platelet Ag | 2001 |
Increased plasma nitrites in migraine and cluster headache patients in interictal period: basal hyperactivity of L-arginine-NO pathway?
Topics: Adult; Arginine; Cluster Headache; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitric Oxi | 2002 |
[Study of "medical headaches". 4. Discussion of the relative incidence found with the nitrite induction test].
Topics: Headache; Humans; Italy; Migraine Disorders; Nitrites; Nitroglycerin | 1968 |