nitrites has been researched along with Metabolic Syndrome in 24 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Resistin and uric acid, surrogate plasma markers of metabolic syndrome, were decreased." | 7.76 | Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. ( Alfredo Martinez, J; Bour, S; Carpéné, C; Iffiú-Soltész, Z; Lomba, A; Milagro, FI; Pellati, F; Portillo, MP; Szöko, E; Valet, P; Wanecq, E; Woodley, J, 2010) |
| "Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner." | 7.76 | Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. ( Aihara, K; Akaike, M; Dagvasumberel, M; Hirata, Y; Ishikawa, K; Iwase, T; Koshiba, K; Kusunose, K; Matsumoto, T; Niki, T; Sata, M; Soeki, T; Sumitomo-Ueda, Y; Taketani, Y; Tomita, N; Wakatsuki, T; Yagi, S; Yamada, H; Yamaguchi, K; Yoshida, S, 2010) |
| " The present study was designed to evaluate the effect of the methanol extract of Sorbus commixta cortex (MSC) on vascular inflammation in a rat model of the metabolic syndrome induced by a high Frc-diet." | 7.74 | Methanol extract of Sorbus commixta cortex prevents vascular inflammation in rats with a high fructose-induced metabolic syndrome. ( Kang, DG; Kim, JS; Lee, AS; Lee, DH; Lee, HS; Sohn, EJ, 2007) |
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 7.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "We evaluated the association of plasma total homocysteine (tHcy), cardiac risk factors and total nitrite in coronary artery disease (CAD) patients, cardiac syndrome X patients and in healthy subjects." | 7.72 | The association of plasma homocysteine, coronary risk factors and serum nitrite in patients with coronary artery disease, vascular syndrome x and healthy subjects. ( Cevik, C; Göldeli, E; Güneri, S; Savaş, S; Soysal, D; Sözmen, E; Susam, I, 2003) |
| " Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease." | 5.42 | Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015) |
| "Asiatic acid is a triterpenoid isolated from Centella asiatica." | 5.40 | Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014) |
| " Resistin and uric acid, surrogate plasma markers of metabolic syndrome, were decreased." | 3.76 | Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. ( Alfredo Martinez, J; Bour, S; Carpéné, C; Iffiú-Soltész, Z; Lomba, A; Milagro, FI; Pellati, F; Portillo, MP; Szöko, E; Valet, P; Wanecq, E; Woodley, J, 2010) |
| "Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner." | 3.76 | Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. ( Aihara, K; Akaike, M; Dagvasumberel, M; Hirata, Y; Ishikawa, K; Iwase, T; Koshiba, K; Kusunose, K; Matsumoto, T; Niki, T; Sata, M; Soeki, T; Sumitomo-Ueda, Y; Taketani, Y; Tomita, N; Wakatsuki, T; Yagi, S; Yamada, H; Yamaguchi, K; Yoshida, S, 2010) |
| "This study investigated the association between nephropathy and oxidative stress, by measurement of systolic blood pressure, lipid peroxidation, activities of catalase, manganese- and copper-zinc-superoxide dismutase and endothelial nitric oxide synthase expression and concentrations of nitrates/nitrites in kidneys from rats with Metabolic Syndrome." | 3.75 | Association of renal damage and oxidative stress in a rat model of metabolic syndrome. Influence of gender. ( Baños, G; Diaz-Diaz, E; El Hafidi, M; Pérez-Torres, I; Roque, P, 2009) |
| " The present study was designed to evaluate the effect of the methanol extract of Sorbus commixta cortex (MSC) on vascular inflammation in a rat model of the metabolic syndrome induced by a high Frc-diet." | 3.74 | Methanol extract of Sorbus commixta cortex prevents vascular inflammation in rats with a high fructose-induced metabolic syndrome. ( Kang, DG; Kim, JS; Lee, AS; Lee, DH; Lee, HS; Sohn, EJ, 2007) |
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 3.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "We evaluated the association of plasma total homocysteine (tHcy), cardiac risk factors and total nitrite in coronary artery disease (CAD) patients, cardiac syndrome X patients and in healthy subjects." | 3.72 | The association of plasma homocysteine, coronary risk factors and serum nitrite in patients with coronary artery disease, vascular syndrome x and healthy subjects. ( Cevik, C; Göldeli, E; Güneri, S; Savaş, S; Soysal, D; Sözmen, E; Susam, I, 2003) |
| "Metabolic syndrome (MetS) denotes a clustering of risk factors that may affect nitric oxide (NO) bioavailability and predispose to cardiovascular diseases, which are delayed by exercise training." | 2.73 | Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome. ( Casella-Filho, A; Chagas, AC; Gomes, VA; Tanus-Santos, JE, 2008) |
| "Obesity, type 2 diabetes and the metabolic syndrome are associated with a decrease in NO bioavailability." | 2.53 | Dietary inorganic nitrate: From villain to hero in metabolic disease? ( Griffin, JL; McNally, B; Roberts, LD, 2016) |
| " Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease." | 1.42 | Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015) |
| "Asiatic acid is a triterpenoid isolated from Centella asiatica." | 1.40 | Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014) |
| "We measured ischemic reactive hyperemia (IRH), plasma levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), total nitrite, lipid peroxidation products (LPO), hydrogen peroxide (H2O2), superoxide dismutase (SOD) and glutathione peroxidase (GPx) plasma activities." | 1.39 | Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study. ( Delgado-Lista, J; Fuentes, F; Lopez-Miranda, J; Marin, C; Peña-Orihuela, P; Perez-Jimenez, F; Perez-Martinez, P; Roche, HM; Tinahones, FJ; Tunez, I; Yubero-Serrano, EM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Koka, S | 1 |
| Xi, L | 1 |
| Kukreja, RC | 1 |
| Kina-Tanada, M | 1 |
| Sakanashi, M | 1 |
| Tanimoto, A | 1 |
| Kaname, T | 1 |
| Matsuzaki, T | 1 |
| Noguchi, K | 1 |
| Uchida, T | 1 |
| Nakasone, J | 1 |
| Kozuka, C | 1 |
| Ishida, M | 1 |
| Kubota, H | 1 |
| Taira, Y | 1 |
| Totsuka, Y | 1 |
| Kina, SI | 1 |
| Sunakawa, H | 1 |
| Omura, J | 1 |
| Satoh, K | 1 |
| Shimokawa, H | 1 |
| Yanagihara, N | 1 |
| Maeda, S | 1 |
| Ohya, Y | 1 |
| Matsushita, M | 1 |
| Masuzaki, H | 1 |
| Arasaki, A | 1 |
| Tsutsui, M | 1 |
| Lundberg, JO | 1 |
| Carlström, M | 1 |
| Weitzberg, E | 1 |
| Yubero-Serrano, EM | 1 |
| Delgado-Lista, J | 1 |
| Peña-Orihuela, P | 1 |
| Perez-Martinez, P | 1 |
| Fuentes, F | 1 |
| Marin, C | 1 |
| Tunez, I | 1 |
| Tinahones, FJ | 1 |
| Perez-Jimenez, F | 1 |
| Roche, HM | 1 |
| Lopez-Miranda, J | 1 |
| Caimi, G | 2 |
| Hopps, E | 2 |
| Montana, M | 2 |
| Carollo, C | 1 |
| Calandrino, V | 1 |
| Incalcaterra, E | 1 |
| Canino, B | 2 |
| Lo Presti, R | 2 |
| Pakdeechote, P | 1 |
| Bunbupha, S | 1 |
| Kukongviriyapan, U | 1 |
| Prachaney, P | 1 |
| Khrisanapant, W | 1 |
| Kukongviriyapan, V | 1 |
| Noto, D | 1 |
| Averna, MR | 1 |
| Polhemus, DJ | 1 |
| Bradley, JM | 1 |
| Islam, KN | 1 |
| Brewster, LP | 1 |
| Calvert, JW | 1 |
| Tao, YX | 1 |
| Chang, CC | 1 |
| Pipinos, II | 1 |
| Goodchild, TT | 1 |
| Lefer, DJ | 1 |
| Singamsetty, S | 1 |
| Watanabe, Y | 1 |
| Guo, L | 1 |
| Corey, C | 1 |
| Wang, Y | 1 |
| Tejero, J | 1 |
| McVerry, BJ | 1 |
| Gladwin, MT | 1 |
| Shiva, S | 1 |
| O'Donnell, CP | 1 |
| McNally, B | 1 |
| Griffin, JL | 1 |
| Roberts, LD | 1 |
| Fattakhov, NS | 1 |
| Vasilenko, MA | 1 |
| Skuratovskaia, DA | 1 |
| Kulikov, DI | 1 |
| Kirienkova, EV | 1 |
| Zatolokin, PA | 1 |
| Beletskaya, MA | 1 |
| Litvinova, LS | 1 |
| Oruc, CU | 1 |
| Akpinar, YE | 1 |
| Amikishiyev, S | 1 |
| Uzum, AK | 1 |
| Salmaslioglu, A | 1 |
| Gurdol, F | 1 |
| Omer, B | 1 |
| Ohtake, K | 1 |
| Ehara, N | 1 |
| Chiba, H | 1 |
| Nakano, G | 1 |
| Sonoda, K | 1 |
| Ito, J | 1 |
| Uchida, H | 1 |
| Kobayashi, J | 1 |
| Zahedi Asl, S | 1 |
| Ghasemi, A | 1 |
| Azizi, F | 1 |
| Gomes, VA | 1 |
| Casella-Filho, A | 1 |
| Chagas, AC | 1 |
| Tanus-Santos, JE | 1 |
| Pérez-Torres, I | 1 |
| Roque, P | 1 |
| El Hafidi, M | 1 |
| Diaz-Diaz, E | 1 |
| Baños, G | 1 |
| Iffiú-Soltész, Z | 1 |
| Wanecq, E | 1 |
| Lomba, A | 1 |
| Portillo, MP | 1 |
| Pellati, F | 1 |
| Szöko, E | 1 |
| Bour, S | 1 |
| Woodley, J | 1 |
| Milagro, FI | 1 |
| Alfredo Martinez, J | 1 |
| Valet, P | 1 |
| Carpéné, C | 1 |
| Yagi, S | 1 |
| Akaike, M | 1 |
| Aihara, K | 1 |
| Iwase, T | 1 |
| Ishikawa, K | 1 |
| Yoshida, S | 1 |
| Sumitomo-Ueda, Y | 1 |
| Kusunose, K | 1 |
| Niki, T | 1 |
| Yamaguchi, K | 1 |
| Koshiba, K | 1 |
| Hirata, Y | 1 |
| Dagvasumberel, M | 1 |
| Taketani, Y | 1 |
| Tomita, N | 1 |
| Yamada, H | 1 |
| Soeki, T | 1 |
| Wakatsuki, T | 1 |
| Matsumoto, T | 1 |
| Sata, M | 1 |
| Barona, J | 1 |
| Aristizabal, JC | 1 |
| Blesso, CN | 1 |
| Volek, JS | 1 |
| Fernandez, ML | 1 |
| Soysal, D | 1 |
| Savaş, S | 1 |
| Susam, I | 1 |
| Cevik, C | 1 |
| Göldeli, E | 1 |
| Sözmen, E | 1 |
| Güneri, S | 1 |
| Cavuşoglu, E | 1 |
| Wang, X | 1 |
| Hattori, Y | 1 |
| Satoh, H | 1 |
| Iwata, C | 1 |
| Banba, N | 1 |
| Monden, T | 1 |
| Uchida, K | 1 |
| Kamikawa, Y | 1 |
| Kasai, K | 1 |
| Kang, DG | 1 |
| Sohn, EJ | 1 |
| Lee, AS | 1 |
| Kim, JS | 1 |
| Lee, DH | 1 |
| Lee, HS | 1 |
| Matsuzaki, G | 1 |
| Ishizaka, N | 1 |
| Furuta, K | 1 |
| Hongo, M | 1 |
| Saito, K | 1 |
| Sakurai, R | 1 |
| Koike, K | 1 |
| Nagai, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Supplementation With One Form of L-arginine on Vascular Endothelial Function in Healthy Subjects Featuring Risk Factors Related to the Metabolic Syndrome.[NCT02354794] | 36 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| Cardioprotective Effects of Freeze Dried Grape Powder Supplementation on Blood Pressure and Plasma Lipids/Lipoproteins: A Pilot Study[NCT03659695] | 20 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitrites and Metabolic Syndrome
| Article | Year |
|---|---|
Metabolic Effects of Dietary Nitrate in Health and Disease.
Topics: Animals; Cardiovascular System; Diabetes Mellitus, Type 2; Diet; Humans; Metabolic Syndrome; Mice; M | 2018 |
Dietary inorganic nitrate: From villain to hero in metabolic disease?
Topics: Adipose Tissue; Biological Availability; Diabetes Mellitus, Type 2; Diet; Heart; Humans; Hypertensio | 2016 |
2 trials available for nitrites and Metabolic Syndrome
| Article | Year |
|---|---|
Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome.
Topics: Adult; Arginine; Biomarkers; Cyclic GMP; Exercise Therapy; Humans; Lipid Peroxides; Metabolic Syndro | 2008 |
Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation in men with metabolic syndrome.
Topics: Adult; Aged; Biomarkers; Blood Pressure; Brachial Artery; Cross-Over Studies; Endothelium, Vascular; | 2012 |
20 other studies available for nitrites and Metabolic Syndrome
| Article | Year |
|---|---|
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dyslipidemias; Heart; Insulin Resistance; Male; | 2020 |
Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice.
Topics: Animals; Cardiovascular System; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Nitrates; Nitric | 2017 |
Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study.
Topics: Aged; Anthropometry; Antioxidants; Biomarkers; Blood Pressure; Endothelium, Vascular; Female; Glutat | 2013 |
Nitric oxide metabolites (nitrite and nitrate) in several clinical condition.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Humans; Hypertensio | 2014 |
Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diet; Diet, High-Fat; Gene Expressio | 2014 |
Lipid peroxidation, nitric oxide metabolites, and their ratio in a group of subjects with metabolic syndrome.
Topics: Adult; Female; Humans; Lipid Peroxidation; Lipoproteins, HDL; Male; Metabolic Syndrome; Middle Aged; | 2014 |
Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.
Topics: Angiogenesis Inducing Agents; Animals; Delayed-Action Preparations; Disease Models, Animal; Hindlimb | 2015 |
Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.
Topics: Animals; Blood Pressure; Body Weight; Cell Respiration; Insulin Resistance; Male; Metabolic Syndrome | 2015 |
[Pathogenetic significance of C774T single nucleotide polymorphism of the endothelial NO synthase gene in the development of metabolic syndrome].
Topics: Adult; Case-Control Studies; Endothelin-1; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Mu | 2016 |
Hypovitaminosis D is Associated with Endothelial Dysfunction in Patients with Metabolic Syndrome.
Topics: Adult; Asymptomatic Diseases; Atherosclerosis; Biomarkers; Calcifediol; Carotid Intima-Media Thickne | 2017 |
Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice.
Topics: Animals; Body Weight; Chemokine CCL2; Diet; Diet, High-Fat; Eating; Fatty Liver; Female; Insulin Res | 2017 |
Serum nitric oxide metabolites in subjects with metabolic syndrome.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Confidence Intervals; Diabetes Complications; Fema | 2008 |
Association of renal damage and oxidative stress in a rat model of metabolic syndrome. Influence of gender.
Topics: Animals; Catalase; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Hormone Replacement T | 2009 |
Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice.
Topics: Adipocytes; Administration, Oral; Animals; Aorta; Benzylamines; Blood Glucose; Cholesterol; Hydrogen | 2010 |
Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Anticholesteremic Agents; Azetidines; C-Reactive Pro | 2010 |
The association of plasma homocysteine, coronary risk factors and serum nitrite in patients with coronary artery disease, vascular syndrome x and healthy subjects.
Topics: Adult; Aged; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Angiography; Coronar | 2003 |
Editorial comment: plasma homocysteine, coronary risk factors and serum nitrite in coronary artery disease and vascular syndrome X.
Topics: Coronary Artery Disease; Homocysteine; Humans; Metabolic Syndrome; Nitrites; Radiography; Risk Facto | 2003 |
Tetrahydrobiopterin prevents endothelial dysfunction and restores adiponectin levels in rats.
Topics: Adiponectin; Adipose Tissue; Animals; Aorta, Thoracic; Biopterins; Blood Pressure; Endothelium, Vasc | 2007 |
Methanol extract of Sorbus commixta cortex prevents vascular inflammation in rats with a high fructose-induced metabolic syndrome.
Topics: Animals; Aorta, Thoracic; Cell Adhesion Molecules; Cyclic GMP; Disease Models, Animal; Endothelin-1; | 2007 |
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium | 2008 |