nitrites has been researched along with Leishmaniasis, Visceral in 17 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leishmaniasis is a parasitic disease caused by Leishmania protozoa, which presents a large spectrum of clinical manifestations." | 1.72 | Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection. ( Carvalho, AMRS; Coelho, EAF; da Silva, AD; Duarte, MC; Freitas, CS; Glanzmann, N; Lage, DP; Martins, VT; Mendonça, DVC; Menezes-Souza, D; Oliveira-da-Silva, JA; Ribeiro Antinarelli, LM; Soares Coimbra, E; Tavares, GSV, 2022) |
| " The only orally bioavailable drug miltefosine is toxic, whereas liposomal amphotericin B (AmpB) is expensive." | 1.62 | Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice. ( Bhattacharjee, S; Das, A; Das, MC; Ghosh, C; Jawed, JJ; Majumdar, S; Parveen, S; Saha, B, 2021) |
| "Amphotericin B is a well-established pharmacologically approved drug; however, mainly toxicity is a foremost issue with that drug." | 1.62 | Synergic effect of eugenol oleate with amphotericin B augments anti-leishmanial immune response in experimental visceral leishmaniasis in vitro and in vivo. ( Charan Raja, MR; Debnath, J; Jayaraman, A; Kar, A; Mahapatra, SK; Srinivasan, S, 2021) |
| "Visceral leishmaniasis is a life-threatening disease characterized by intense parasitism of the spleen, liver, and bone marrow." | 1.43 | Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages. ( Aragão, MT; Braz, JM; da Silva, ÂM; de Almeida, RP; de Jesus, AR; de Moura, TR; de Oliveira, FA; Santos, LF; Santos, ML; Santos, PL, 2016) |
| "Human visceral leishmaniasis is caused by Leishmania donovani." | 1.35 | Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote. ( Basu, R; Bhaumik, S; Bhaumik, SK; De, T; Naskar, K; Roy, S; Roychoudhury, K; Singh, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Ribeiro Antinarelli, LM | 1 |
| Glanzmann, N | 1 |
| Mendonça, DVC | 1 |
| Lage, DP | 2 |
| Oliveira-da-Silva, JA | 1 |
| Tavares, GSV | 1 |
| Carvalho, AMRS | 1 |
| Freitas, CS | 1 |
| Martins, VT | 2 |
| Duarte, MC | 2 |
| Menezes-Souza, D | 1 |
| da Silva, AD | 1 |
| Coelho, EAF | 1 |
| Soares Coimbra, E | 1 |
| Das, A | 1 |
| Jawed, JJ | 1 |
| Das, MC | 1 |
| Parveen, S | 1 |
| Ghosh, C | 1 |
| Majumdar, S | 2 |
| Saha, B | 1 |
| Bhattacharjee, S | 2 |
| Kar, A | 1 |
| Jayaraman, A | 1 |
| Charan Raja, MR | 1 |
| Srinivasan, S | 1 |
| Debnath, J | 1 |
| Mahapatra, SK | 1 |
| Ibraim, IC | 1 |
| de Assis, RR | 1 |
| Pessoa, NL | 1 |
| Campos, MA | 1 |
| Melo, MN | 1 |
| Turco, SJ | 1 |
| Soares, RP | 1 |
| Chávez-Fumagalli, MA | 1 |
| Garde, E | 1 |
| Costa, LE | 1 |
| da Silva, VG | 1 |
| Silva, VG | 1 |
| Oliveira, JS | 1 |
| Magalhães-Soares, DF | 1 |
| Teixeira, SM | 1 |
| Fernandes, AP | 1 |
| Soto, M | 1 |
| Tavares, CA | 1 |
| Coelho, EA | 1 |
| Leal, JM | 1 |
| Mosquini, M | 1 |
| Covre, LP | 1 |
| Stagmiller, NP | 1 |
| Rodrigues, RR | 1 |
| Christensen, D | 1 |
| de Matos Guedes, HL | 1 |
| Guedes, HL | 1 |
| Rossi-Bergmann, B | 1 |
| Gomes, DC | 1 |
| de Moura, TR | 1 |
| Santos, ML | 1 |
| Braz, JM | 1 |
| Santos, LF | 1 |
| Aragão, MT | 1 |
| de Oliveira, FA | 1 |
| Santos, PL | 1 |
| da Silva, ÂM | 1 |
| de Jesus, AR | 1 |
| de Almeida, RP | 1 |
| Bhardwaj, S | 1 |
| Vasishta, RK | 1 |
| Arora, SK | 1 |
| Datta, S | 1 |
| Adak, R | 1 |
| Chakraborty, P | 1 |
| Haldar, AK | 1 |
| Chakraborty, A | 1 |
| Roy, S | 2 |
| Manna, M | 1 |
| Peruhype-Magalhães, V | 1 |
| Martins-Filho, OA | 1 |
| Prata, A | 1 |
| Silva, Lde A | 1 |
| Rabello, A | 1 |
| Teixeira-Carvalho, A | 1 |
| Figueiredo, RM | 1 |
| Guimarães-Carvalho, SF | 1 |
| Ferrari, TC | 1 |
| Van Weyenbergh, J | 1 |
| Correa-Oliveira, R | 1 |
| Khambu, B | 1 |
| Mehta, KD | 1 |
| Rijal, S | 1 |
| Lamsal, M | 1 |
| Majhi, S | 1 |
| Baral, N | 1 |
| Bhaumik, SK | 1 |
| Singh, M | 1 |
| Basu, R | 1 |
| Bhaumik, S | 1 |
| Roychoudhury, K | 1 |
| Naskar, K | 1 |
| De, T | 1 |
| Jones, LA | 1 |
| Anthony, JP | 1 |
| Henriquez, FL | 1 |
| Lyons, RE | 1 |
| Nickdel, MB | 1 |
| Carter, KC | 1 |
| Alexander, J | 1 |
| Roberts, CW | 1 |
| Bhattacharyya, S | 1 |
| Ghosh, S | 1 |
| Jhonson, PL | 1 |
| Bhattacharya, SK | 1 |
| Das, L | 1 |
| Datta, N | 1 |
| Bandyopadhyay, S | 1 |
| Das, PK | 1 |
| Kumar, R | 1 |
| Pai, K | 1 |
| Sundar, S | 1 |
| Gantt, KR | 1 |
| Goldman, TL | 1 |
| McCormick, ML | 1 |
| Miller, MA | 1 |
| Jeronimo, SM | 1 |
| Nascimento, ET | 1 |
| Britigan, BE | 1 |
| Wilson, ME | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Center, Randomized, Controlled Trial of the Safety and Efficacy of Progesterone for the Treatment of COVID-19 in Hospitalized Men[NCT04365127] | Phase 1 | 40 participants (Actual) | Interventional | 2020-04-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 other studies available for nitrites and Leishmaniasis, Visceral
| Article | Year |
|---|---|
Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection.
Topics: Animals; Antiprotozoal Agents; Leishmania infantum; Leishmaniasis; Leishmaniasis, Visceral; Mice; Mi | 2022 |
Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cells, Cultured; Cytokines; Drug Synergism; Gene Expr | 2021 |
Synergic effect of eugenol oleate with amphotericin B augments anti-leishmanial immune response in experimental visceral leishmaniasis in vitro and in vivo.
Topics: Amphotericin B; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Synergism; Drug Th | 2021 |
Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cytokines; Female; Gene Expression Regulation; Glycosphi | 2013 |
Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis.
Topics: Animals; Antigens, Protozoan; Cytokines; Dogs; Female; Immunity, Humoral; Leishmania infantum; Leish | 2015 |
Intranasal vaccination with killed Leishmania amazonensis promastigotes antigen (LaAg) associated with CAF01 adjuvant induces partial protection in BALB/c mice challenged with Leishmania (infantum) chagasi.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Protozoan; Antigens, Protoz | 2015 |
Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.
Topics: Adult; Amphotericin B; Animals; Antimony; Cytokines; Drug Resistance; Drug Tolerance; Humans; Immune | 2016 |
Vaccination with a novel recombinant Leishmania antigen plus MPL provides partial protection against L. donovani challenge in experimental model of visceral leishmaniasis.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Antigens, Protozoan; Cricetinae; Cytokines; | 2009 |
Radio-attenuated leishmanial parasites as immunoprophylactic agent against experimental murine visceral leishmaniasis.
Topics: Animals; Cricetinae; Cytokines; Female; Gamma Rays; Humans; Leishmania donovani; Leishmaniasis, Visc | 2012 |
Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-gamma and interleukin-10 and low frequency of tumour necrosis factor-alpha(+) monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania chagas
Topics: Adolescent; Adult; Aged; Cells, Cultured; Child; Child, Preschool; Cytokines; Female; Humans; Immuni | 2006 |
Serum nitrite level and adenosine deaminase activity is altered in visceral leishmaniasis.
Topics: Adenosine Deaminase; Adult; Analysis of Variance; Antimony Sodium Gluconate; Antiprotozoal Agents; F | 2007 |
Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote.
Topics: Agglutination; Animals; Chromatography, Affinity; Clone Cells; Galactosidases; Galactosyltransferase | 2008 |
Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors.
Topics: Animals; Cell Survival; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Down-Regul | 2008 |
Immunomodulatory role of interleukin-10 in visceral leishmaniasis: defective activation of protein kinase C-mediated signal transduction events.
Topics: Adjuvants, Immunologic; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme | 2001 |
Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response.
Topics: Animals; Cells, Cultured; Cystatins; Cysteine Proteinase Inhibitors; Cytokines; Disease Progression; | 2001 |
Reactive oxygen intermediates, nitrite and IFN-gamma in Indian visceral leishmaniasis.
Topics: Adolescent; Adult; Amphotericin B; Female; Follow-Up Studies; Humans; Interferon-gamma; Leishmaniasi | 2001 |
Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; | 2001 |