Page last updated: 2024-10-19

nitrites and Insulin Resistance

nitrites has been researched along with Insulin Resistance in 43 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"Fructose-induced hypertension was used to test the hypothesis that taurine supplementation and/or exercise can prevent hypertension and increase exercise capacity."7.77Taurine prevents hypertension and increases exercise capacity in rats with fructose-induced hypertension. ( Go, HK; Hong, CU; Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Kim, SZ; Lee, YU; Park, HM; Rahman, MM, 2011)
" Resistin and uric acid, surrogate plasma markers of metabolic syndrome, were decreased."7.76Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. ( Alfredo Martinez, J; Bour, S; Carpéné, C; Iffiú-Soltész, Z; Lomba, A; Milagro, FI; Pellati, F; Portillo, MP; Szöko, E; Valet, P; Wanecq, E; Woodley, J, 2010)
" Liver dysfunction in fructose-fed rats was evident from a rise in transaminase and total bilirubin, a decrease in the albumin/globulin ratio in plasma, a decrease in nitrite and arginase, and an increase in protein carbonyl and nitrosothiol content in the liver."7.76Insulin resistance induced by a high-fructose diet potentiates thioacetamide hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
"Asiatic acid is a triterpenoid isolated from Centella asiatica."5.40Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014)
" The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days."5.36Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
"Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue."5.36Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010)
"Melatonin treatment of IH-exposed animals decreased blood pressure, blood glucose, and ROS and nitrite/nitrate levels, and increased vasodilation and capillary perfusion."5.35Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia. ( Bertuglia, S; Reiter, RJ, 2009)
"Fructose-induced hypertension was used to test the hypothesis that taurine supplementation and/or exercise can prevent hypertension and increase exercise capacity."3.77Taurine prevents hypertension and increases exercise capacity in rats with fructose-induced hypertension. ( Go, HK; Hong, CU; Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Kim, SZ; Lee, YU; Park, HM; Rahman, MM, 2011)
" MRFs (serum lipid profile, insulin resistance indexes, blood pressure) in addition to uric acid, homocysteine, leptin, and inflammatory markers were measured."3.77Nitric oxide production is increased in severely obese children and related to markers of oxidative stress and inflammation. ( Alonso-Iglesias, E; Codoñer-Franch, P; Megías-Vericat, J; Murria-Estal, R; Tavárez-Alonso, S; Tortajada-Girbés, M, 2011)
" Resistin and uric acid, surrogate plasma markers of metabolic syndrome, were decreased."3.76Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. ( Alfredo Martinez, J; Bour, S; Carpéné, C; Iffiú-Soltész, Z; Lomba, A; Milagro, FI; Pellati, F; Portillo, MP; Szöko, E; Valet, P; Wanecq, E; Woodley, J, 2010)
" Liver dysfunction in fructose-fed rats was evident from a rise in transaminase and total bilirubin, a decrease in the albumin/globulin ratio in plasma, a decrease in nitrite and arginase, and an increase in protein carbonyl and nitrosothiol content in the liver."3.76Insulin resistance induced by a high-fructose diet potentiates thioacetamide hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
"Essential hypertension has a familial predisposition, but the phenotype of elevated blood pressure has delayed penetrance."2.70Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences. ( Gabbai, FB; Henry, RR; Kailasam, MT; Martinez, JA; Miller, LM; O'Connor, DT; Parmer, RJ; Tyrell, EA, 2001)
"Vascular insulin resistance is a feature of obesity and type 2 diabetes that contributes to the genesis of vascular disease and glycemic dysregulation."1.72Young Women Are Protected Against Vascular Insulin Resistance Induced by Adoption of an Obesogenic Lifestyle. ( Jurrissen, TJ; Manrique-Acevedo, C; Martinez-Lemus, LA; McMillan, NJ; Padilla, J; Smith, JA; Soares, RN, 2022)
"Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type 2 diabetes."1.46Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats. ( Bakhtiarzadeh, F; Farrokhfall, K; Ghasemi, A; Gheibi, S; Jeddi, S; Zardooz, H, 2017)
"Asiatic acid is a triterpenoid isolated from Centella asiatica."1.40Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014)
"Aliskiren treatment, either concurrent or subsequent, elevated plasma NO(2) levels and reduced systolic hypertension, insulin resistance, dyslipidemia, aortic lipid peroxide levels and aortic wall hypertrophy in FHR."1.39Direct renin inhibitor prevents and ameliorates insulin resistance, aortic endothelial dysfunction and vascular remodeling in fructose-fed hypertensive rats. ( Chou, CL; Fang, TC; Lee, TJ; Pang, CY, 2013)
"Nonalcoholic fatty liver disease is a chronic metabolic disorder with significant impact on cardiovascular and liver mortality."1.38Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. ( Bucchieri, F; Bugianesi, E; Galvano, F; Li Volti, G; Mangiameli, A; Marino Gammazza, A; Marino, A; Parola, M; Paternostro, C; Salamone, F; Tibullo, D, 2012)
"Obesity and obstructive sleep apnea (OSA) are both associated with the prevalence of major cardiovascular illnesses and certain common factors they are considered responsible for, such as stress oxidative increase, sympathetic tonus and resistance to insulin."1.36Effects of nasal continuous positive airway pressure treatment on oxidative stress and adiponectin levels in obese patients with obstructive sleep apnea. ( Ataíde, L; Bezerra, Ade A; de Castro, CM; de Lima, AM; Franco, CM; Halpern, A, 2010)
"Obesity and hypertension are the two major risk factors that contribute to the progression of end-stage renal disease."1.36Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats. ( Elmarakby, AA; Imig, JD, 2010)
" The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days."1.36Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
"Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue."1.36Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010)
"Melatonin treatment of IH-exposed animals decreased blood pressure, blood glucose, and ROS and nitrite/nitrate levels, and increased vasodilation and capillary perfusion."1.35Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia. ( Bertuglia, S; Reiter, RJ, 2009)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.65)18.2507
2000's10 (23.26)29.6817
2010's28 (65.12)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Aggarwal, H1
Pathak, P1
Kumar, Y1
Jagavelu, K1
Dikshit, M2
Smith, JA1
Soares, RN1
McMillan, NJ1
Jurrissen, TJ1
Martinez-Lemus, LA1
Padilla, J1
Manrique-Acevedo, C1
Koka, S1
Xi, L1
Kukreja, RC1
Dai, X1
Ding, Y1
Zhang, Z1
Cai, X1
Bao, L1
Li, Y1
Radika, MK1
Viswanathan, P3
Anuradha, CV4
Salman, ZK1
Refaat, R1
Selima, E1
El Sarha, A1
Ismail, MA1
White, DL1
Collinson, A1
Pakdeechote, P1
Bunbupha, S1
Kukongviriyapan, U1
Prachaney, P1
Khrisanapant, W1
Kukongviriyapan, V1
Ohtake, K2
Nakano, G2
Ehara, N2
Sonoda, K2
Ito, J2
Uchida, H2
Kobayashi, J2
Singamsetty, S1
Watanabe, Y1
Guo, L1
Corey, C1
Wang, Y1
Tejero, J1
McVerry, BJ1
Gladwin, MT1
Shiva, S1
O'Donnell, CP1
Rafraf, M1
Bazyun, B1
Sarabchian, MA1
Safaeiyan, A1
Gargari, BP1
Stanimirovic, J1
Obradovic, M1
Jovanovic, A1
Sudar-Milovanovic, E1
Zafirovic, S1
Pitt, SJ1
Stewart, AJ1
Isenovic, ER1
Lane-Cordova, AD1
Witmer, JR1
Dubishar, K1
DuBose, LE1
Chenard, CA1
Siefers, KJ1
Myers, JE1
Points, LJ1
Pierce, GL1
Gheibi, S1
Bakhtiarzadeh, F1
Jeddi, S1
Farrokhfall, K1
Zardooz, H1
Ghasemi, A1
Chiba, H1
Bertuglia, S1
Reiter, RJ1
de Lima, AM1
Franco, CM1
de Castro, CM1
Bezerra, Ade A1
Ataíde, L1
Halpern, A1
Elmarakby, AA1
Imig, JD1
Iffiú-Soltész, Z1
Wanecq, E1
Lomba, A1
Portillo, MP1
Pellati, F1
Szöko, E1
Bour, S1
Woodley, J1
Milagro, FI1
Alfredo Martinez, J1
Valet, P1
Carpéné, C1
Pooranaperundevi, M2
Sumiyabanu, MS2
Sundarapandiyan, R2
Wu, HT1
Chen, W1
Cheng, KC1
Yeh, CH1
Shen, KH1
Cheng, JT1
Rahman, MM1
Park, HM1
Kim, SJ1
Go, HK1
Kim, GB1
Hong, CU1
Lee, YU1
Kim, SZ1
Kim, JS1
Kang, HS1
Codoñer-Franch, P1
Tavárez-Alonso, S1
Murria-Estal, R1
Megías-Vericat, J1
Tortajada-Girbés, M1
Alonso-Iglesias, E1
Prakash, P1
Khanna, V1
Singh, V1
Jyoti, A1
Jain, M1
Keshari, RS1
Barthwal, MK1
Salamone, F1
Galvano, F1
Marino Gammazza, A1
Marino, A1
Paternostro, C1
Tibullo, D1
Bucchieri, F1
Mangiameli, A1
Parola, M1
Bugianesi, E1
Li Volti, G1
Kadiiska, MB1
Bonini, MG1
Ruggiero, C1
Cleland, E1
Wicks, S1
Stadler, K1
Ozgen, IT1
Tascilar, ME1
Bilir, P1
Boyraz, M1
Guncikan, MN1
Akay, C1
Dundaroz, R1
Conceição, EP1
Franco, JG1
Oliveira, E1
Resende, AC1
Amaral, TA1
Peixoto-Silva, N1
Passos, MC1
Moura, EG1
Lisboa, PC1
Seet, RC1
Loke, WM1
Khoo, CM1
Chew, SE1
Chong, WL1
Quek, AM1
Lim, EC1
Halliwell, B1
Chou, CL1
Pang, CY1
Lee, TJ1
Fang, TC1
Gilchrist, M1
Winyard, PG1
Aizawa, K1
Anning, C1
Shore, A1
Benjamin, N1
Ohtoshi, K1
Yamasaki, Y1
Gorogawa, S1
Hayaishi-Okano, R1
Node, K1
Matsuhisa, M1
Kajimoto, Y1
Hori, M1
Hasegawa, K1
Yoshida, H1
Ura, N1
Murakami, H1
Hagiwara, M1
Shimamoto, K1
Hsieh, PS1
Vidonho, AF1
da Silva, AA1
Catanozi, S1
Rocha, JC1
Beutel, A1
Carillo, BA1
Furukawa, LN1
Campos, RR1
de Toledo Bergamaschi, CM1
Carpinelli, AR1
Quintão, EC1
Dolnikoff, MS1
Heimann, JC1
Thirunavukkarasu, V1
Anitha Nandhini, AT1
Tsuchiya, K1
Sakai, H1
Suzuki, N1
Iwashima, F1
Yoshimoto, T1
Shichiri, M1
Hirata, Y1
Fujiwara, K1
Hayashi, K1
Matsuda, H1
Kubota, E1
Honda, M1
Ozawa, Y1
Saruta, T1
Kurioka, S1
Koshimura, K1
Murakami, Y1
Nishiki, M1
Kato, Y1
Vasdev, S1
Ford, CA1
Longerich, L1
Parai, S1
Gadag, V1
Wadhawan, S1
O'Connor, DT1
Tyrell, EA1
Kailasam, MT1
Miller, LM1
Martinez, JA1
Henry, RR1
Parmer, RJ1
Gabbai, FB1
Duplain, H1
Burcelin, R1
Sartori, C1
Cook, S1
Egli, M1
Lepori, M1
Vollenweider, P1
Pedrazzini, T1
Nicod, P1
Thorens, B1
Scherrer, U1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Estrogen + Estradiol Receptor Alpha Modulator Therapy on Oxidative Stress in Post-menopausal Women With and Without Sleep Apnea[NCT03981341]Phase 336 participants (Anticipated)Interventional2019-11-01Recruiting
Effect of Dapagliflozin on Cardio-Metabolic Risk Factors in Patients With Type-2 Diabetes[NCT03377335]Phase 4186 participants (Anticipated)Interventional2017-12-22Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrites and Insulin Resistance

ArticleYear
Red meat, dietary heme iron, and risk of type 2 diabetes: the involvement of advanced lipoxidation endproducts.
    Advances in nutrition (Bethesda, Md.), 2013, Jul-01, Volume: 4, Issue:4

    Topics: Animals; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Female; Ferritins; Food Handling; Glycatio

2013

Trials

4 trials available for nitrites and Insulin Resistance

ArticleYear
Vitamin E Improves Serum Paraoxonase-1 Activity and Some Metabolic Factors in Patients with Type 2 Diabetes: No Effects on Nitrite/Nitrate Levels.
    Journal of the American College of Nutrition, 2016, Volume: 35, Issue:6

    Topics: Adult; Antioxidants; Aryldialkylphosphatase; Blood Glucose; Diabetes Complications; Diabetes Mellitu

2016
High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans.
    Vascular medicine (London, England), 2016, Volume: 21, Issue:5

    Topics: Administration, Oral; Adult; Beverages; Biomarkers; Brachial Artery; Cardiovascular Diseases; Coconu

2016
Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Aged; Beta vulgaris; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dietary Sup

2013
Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Adult; Amino Acids; Arginine; Cyclic GMP; Female; Genetic Markers; Glomerular Filtration Rate; Human

2001

Other Studies

38 other studies available for nitrites and Insulin Resistance

ArticleYear
Modulation of Insulin Resistance, Dyslipidemia and Serum Metabolome in iNOS Knockout Mice following Treatment with Nitrite, Metformin, Pioglitazone, and a Combination of Ampicillin and Neomycin.
    International journal of molecular sciences, 2021, Dec-24, Volume: 23, Issue:1

    Topics: Ampicillin; Animals; Drug Therapy, Combination; Dyslipidemias; Glucose; Homeostasis; Hypoglycemic Ag

2021
Young Women Are Protected Against Vascular Insulin Resistance Induced by Adoption of an Obesogenic Lifestyle.
    Endocrinology, 2022, 10-11, Volume: 163, Issue:11

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Resistance; Life Style; M

2022
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
    Molecular and cellular biochemistry, 2020, Volume: 468, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dyslipidemias; Heart; Insulin Resistance; Male;

2020
Quercetin but not quercitrin ameliorates tumor necrosis factor-alpha-induced insulin resistance in C2C12 skeletal muscle cells.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Glucose; Hypoglycemic Agents; Insulin Resistance;

2013
Nitric oxide mediates the insulin sensitizing effects of β-sitosterol in high fat diet-fed rats.
    Nitric oxide : biology and chemistry, 2013, Aug-01, Volume: 32

    Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Guanidines; Hepatocytes;

2013
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabet

2013
Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats.
    Nutrients, 2014, Jan-16, Volume: 6, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diet; Diet, High-Fat; Gene Expressio

2014
Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKA(y) mice.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cytokines; Diabetes Mellitus, Experimental; Dia

2015
Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.
    The Journal of physiology, 2015, Jul-15, Volume: 593, Issue:14

    Topics: Animals; Blood Pressure; Body Weight; Cell Respiration; Insulin Resistance; Male; Metabolic Syndrome

2015
A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats.
    Nitric oxide : biology and chemistry, 2016, Apr-01, Volume: 54

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Diet, High-Fat; Female; Glucose; Insulin Resi

2016
Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats.
    Nitric oxide : biology and chemistry, 2017, Apr-01, Volume: 64

    Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Eating; Glucose; I

2017
Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice.
    American journal of physiology. Endocrinology and metabolism, 2017, 04-01, Volume: 312, Issue:4

    Topics: Animals; Body Weight; Chemokine CCL2; Diet; Diet, High-Fat; Eating; Fatty Liver; Female; Insulin Res

2017
Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia.
    Journal of pineal research, 2009, Volume: 46, Issue:3

    Topics: Analysis of Variance; Animals; Blood Glucose; Cricetinae; Glucose Clamp Technique; Hemodynamics; Hyp

2009
Effects of nasal continuous positive airway pressure treatment on oxidative stress and adiponectin levels in obese patients with obstructive sleep apnea.
    Respiration; international review of thoracic diseases, 2010, Volume: 79, Issue:5

    Topics: Adiponectin; Case-Control Studies; Continuous Positive Airway Pressure; Humans; Insulin Resistance;

2010
Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats.
    Clinical science (London, England : 1979), 2010, Volume: 118, Issue:4

    Topics: Acetylcholine; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase 2; Dietary Fat

2010
Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice.
    Pharmacological research, 2010, Volume: 61, Issue:4

    Topics: Adipocytes; Administration, Oral; Animals; Aorta; Benzylamines; Blood Glucose; Cholesterol; Hydrogen

2010
Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity.
    Toxicology and industrial health, 2010, Volume: 26, Issue:2

    Topics: Analysis of Variance; Animals; Biomarkers; Blood Glucose; Carbon Tetrachloride; Carbon Tetrachloride

2010
Insulin resistance induced by a high-fructose diet potentiates thioacetamide hepatotoxicity.
    Singapore medical journal, 2010, Volume: 51, Issue:5

    Topics: Albumins; Animals; Antioxidants; Arginase; Bilirubin; Cytochrome P-450 CYP2E1; Dietary Carbohydrates

2010
Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:11

    Topics: Adipose Tissue; Animals; Cell Movement; Cotton Fiber; Cyclooxygenase 2; Dinoprostone; Disease Models

2010
Taurine prevents hypertension and increases exercise capacity in rats with fructose-induced hypertension.
    American journal of hypertension, 2011, Volume: 24, Issue:5

    Topics: Animals; Blood Glucose; Creatine Kinase; Electrolytes; Fructose; Glutathione; Hypertension; Insulin;

2011
Nitric oxide production is increased in severely obese children and related to markers of oxidative stress and inflammation.
    Atherosclerosis, 2011, Volume: 215, Issue:2

    Topics: Adolescent; Biomarkers; Child; Female; Humans; Inflammation; Insulin Resistance; Male; Nitrates; Nit

2011
Atorvastatin protects against ischemia-reperfusion injury in fructose-induced insulin resistant rats.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:4

    Topics: Animals; Atorvastatin; Endothelium, Vascular; Fructose; Heptanoic Acids; Hydroxymethylglutaryl-CoA R

2011
Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline Deficiency; Cytokines; Di

2012
Thiazolidinedione treatment decreases oxidative stress in spontaneously hypertensive heart failure rats through attenuation of inducible nitric oxide synthase-mediated lipid radical formation.
    Diabetes, 2012, Volume: 61, Issue:3

    Topics: Aldehydes; Animals; Body Composition; Free Radicals; Glucose Intolerance; Heart Failure; Hypertensio

2012
Oxidative stress in obese children and its relation with insulin resistance.
    Journal of pediatric endocrinology & metabolism : JPEM, 2012, Volume: 25, Issue:3-4

    Topics: Adolescent; Blood Glucose; Body Composition; Body Mass Index; Case-Control Studies; Child; Female; G

2012
Oxidative stress programming in a rat model of postnatal early overnutrition--role of insulin resistance.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Catalase; Eating; Female; Glutathione Peroxidase; Insulin; I

2013
Acute effects of cigarette smoking on insulin resistance and arterial stiffness in young adults.
    Atherosclerosis, 2012, Volume: 224, Issue:1

    Topics: Adult; C-Reactive Protein; Female; Hemodynamics; Homeostasis; Humans; Insulin Resistance; Male; Mode

2012
Direct renin inhibitor prevents and ameliorates insulin resistance, aortic endothelial dysfunction and vascular remodeling in fructose-fed hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:2

    Topics: Amides; Animals; Aorta, Thoracic; Dietary Carbohydrates; Disease Models, Animal; Endothelium, Vascul

2013
Association of (-)786T-C mutation of endothelial nitric oxide synthase gene with insulin resistance.
    Diabetologia, 2002, Volume: 45, Issue:11

    Topics: Adult; Aged; Asian People; Base Sequence; Blood Pressure; Cytidine; Diabetes Mellitus, Type 2; DNA P

2002
The role of renal natriuretic and depressor systems in insulin-resistant hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:7

    Topics: Animals; Dopamine; Hypertension; Insulin Resistance; Kallikreins; Kidney; Male; Nitrates; Nitrites;

2004
Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance.
    American journal of hypertension, 2004, Volume: 17, Issue:8

    Topics: Animals; Blood Glucose; Blood Pressure; Fructose; Heart Rate; Hyperinsulinism; Hypertension; Insulin

2004
Perinatal salt restriction: a new pathway to programming insulin resistance and dyslipidemia in adult wistar rats.
    Pediatric research, 2004, Volume: 56, Issue:6

    Topics: Age Factors; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Female; Hyperlipidemias;

2004
Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose-fed rats.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2004, Volume: 174, Issue:8

    Topics: Animals; Biological Transport; Blood Glucose; Blood Pressure; Calcium-Transporting ATPases; Creatine

2004
Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.
    Endocrinology, 2007, Volume: 148, Issue:10

    Topics: Adipose Tissue; Adiposity; Animals; Blood Pressure; Catecholamines; Dietary Fats; Drug Administratio

2007
Altered pressure-natriuresis in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Diuresis; Glomerular Filtration Rate; Insulin;

1999
Reverse correlation between urine nitric oxide metabolites and insulin resistance in patients with type 2 diabetes mellitus.
    Endocrine journal, 2000, Volume: 47, Issue:1

    Topics: Adult; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; H

2000
Aldehyde induced hypertension in rats: prevention by N-acetyl cysteine.
    Artery, 1998, Volume: 23, Issue:1

    Topics: Acetylcysteine; Aldehydes; Animals; Arterioles; Blood Platelets; Blood Pressure; Body Weight; Calciu

1998
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Body Weight; Disease Models, Animal; Glucose;

2001