nitrites has been researched along with Injury, Myocardial Reperfusion in 75 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs." | 7.81 | Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015) |
| "Obesity is a major risk factor for coronary artery disease, but its impact on anesthetic-induced cardioprotective actions is unexplored." | 5.37 | Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia-reperfusion injury: role of AMP-activated protein kinase pathway. ( Cui, WY; Lv, LY; Qu, G; Shi, XM; Song, T; Tian, ZY; Wang, QS; Xu, J, 2011) |
| "Treatment with hesperidin showed a significant increase in tissue nitrite, antioxidant level and reduction in inflammation, arrhythmias and apoptosis." | 5.35 | Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin. ( Balaraman, R; Gandhi, C; Upaganalawar, A, 2009) |
| "Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs." | 3.81 | Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015) |
| " Severities of ischaemia (ST-segment elevation, inhomogeneity of electrical activation) and ventricular arrhythmias (VPBs, VT, VF), plasma nitrate/nitrite levels, as well as myocardial superoxide and nitrotyrosine productions were determined." | 3.77 | Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion? ( Juhász, L; Kaszaki, J; Kiss, A; Kovács, M; Nyeso, E; Seprényi, G; Végh, A, 2011) |
| "Inhibition of arginase protects from myocardial infarction by a mechanism that is dependent on NOS activity and bioavailability of NO by shifting arginine utilization from arginase towards NOS." | 3.76 | Arginase inhibition mediates cardioprotection during ischaemia-reperfusion. ( Gonon, AT; Jung, C; Lundberg, JO; Pernow, J; Sjöquist, PO, 2010) |
| "Previous studies indicate that adenosine supplementation or nitric oxide synthase (NOS) inhibition during reperfusion exert protective effects against myocardial ischemia-reperfusion (I/R) injury." | 3.74 | Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury. ( Bouhaddi, M; Davani, S; Kantelip, JP; Reyssie, H; Rochette, L; Royer, B; Vergely, C, 2007) |
| "Peritonitis sepsis induced multiple organ dysfunction, mitochondrial abnormalities, and increased mortality rate, which were reduced by pharmacological inhibition of mitochondrial transition by cyclosporine derivatives and mitochondrial Bcl-2 overexpression." | 3.73 | Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality. ( Chopin, C; Decoster, B; Favory, R; Hassoun, SM; Lancel, S; Larche, J; Marchetti, P; Neviere, R, 2006) |
| ") is thought to protect against the damaging effects of myocardial ischemia-reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species." | 3.72 | Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. ( Ahluwalia, A; Benjamin, N; Bond, R; McLean, P; Uppal, R; Webb, A, 2004) |
| "Obesity is a major risk factor for coronary artery disease, but its impact on anesthetic-induced cardioprotective actions is unexplored." | 1.37 | Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia-reperfusion injury: role of AMP-activated protein kinase pathway. ( Cui, WY; Lv, LY; Qu, G; Shi, XM; Song, T; Tian, ZY; Wang, QS; Xu, J, 2011) |
| "Hyperglycemia is known to inhibit ischemic and anesthetic preconditioning." | 1.36 | Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling. ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2010) |
| "Treatment with hesperidin showed a significant increase in tissue nitrite, antioxidant level and reduction in inflammation, arrhythmias and apoptosis." | 1.35 | Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin. ( Balaraman, R; Gandhi, C; Upaganalawar, A, 2009) |
| "085 DV." | 1.29 | Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion. ( Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (10.67) | 18.2507 |
| 2000's | 29 (38.67) | 29.6817 |
| 2010's | 33 (44.00) | 24.3611 |
| 2020's | 5 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yassaghi, Y | 1 |
| Jeddi, S | 2 |
| Yousefzadeh, N | 1 |
| Kashfi, K | 1 |
| Ghasemi, A | 2 |
| Liu, Y | 1 |
| Croft, KD | 1 |
| Hodgson, JM | 1 |
| Mori, T | 1 |
| Ward, NC | 1 |
| Koka, S | 1 |
| Xi, L | 1 |
| Kukreja, RC | 1 |
| Rajani, SF | 1 |
| Faghihi, M | 1 |
| Imani, A | 1 |
| Griffiths, K | 1 |
| Lee, JJ | 1 |
| Frenneaux, MP | 1 |
| Feelisch, M | 5 |
| Madhani, M | 1 |
| Totzeck, M | 2 |
| Korste, S | 1 |
| Miinalainen, I | 1 |
| Hendgen-Cotta, UB | 3 |
| Rassaf, T | 5 |
| Cahuê, F | 1 |
| Souza, S | 1 |
| Dos Santos, CFM | 1 |
| Machado, V | 1 |
| Nascimento, JHM | 1 |
| Barcellos, L | 1 |
| Salerno, VP | 1 |
| Vishwakarma, VK | 1 |
| Goyal, A | 2 |
| Gupta, JK | 2 |
| Upadhyay, PK | 1 |
| Yadav, HN | 2 |
| Yellon, DM | 2 |
| He, Z | 1 |
| Khambata, R | 1 |
| Ahluwalia, A | 2 |
| Davidson, SM | 1 |
| Erkens, R | 1 |
| Suvorava, T | 1 |
| Sutton, TR | 1 |
| Fernandez, BO | 3 |
| Mikus-Lelinska, M | 1 |
| Barbarino, F | 1 |
| Flögel, U | 1 |
| Kelm, M | 3 |
| Cortese-Krott, MM | 1 |
| Nagasaka, Y | 1 |
| Steinbicker, AU | 1 |
| Spagnolli, E | 1 |
| Malhotra, R | 1 |
| Bloch, DB | 1 |
| Bloch, KD | 1 |
| Zapol, WM | 1 |
| Inserte, J | 1 |
| Hernando, V | 1 |
| Vilardosa, Ú | 1 |
| Abad, E | 1 |
| Poncelas-Nozal, M | 1 |
| Garcia-Dorado, D | 2 |
| Sobierajski, J | 1 |
| Pagliaro, P | 1 |
| Gattullo, D | 1 |
| Penna, C | 1 |
| Ferdinandy, P | 1 |
| Schulz, R | 1 |
| Nicholson, CK | 2 |
| Lambert, JP | 1 |
| Chow, CW | 1 |
| Lefer, DJ | 6 |
| Calvert, JW | 5 |
| Yang, J | 1 |
| Gonon, AT | 2 |
| Sjöquist, PO | 2 |
| Lundberg, JO | 3 |
| Pernow, J | 2 |
| Toropova, IaG | 1 |
| Antonova, LV | 1 |
| Mukhamadiiarov, RA | 1 |
| Bogdanov, MV | 1 |
| Golovkin, AS | 1 |
| Kovács, M | 2 |
| Kiss, A | 2 |
| Gönczi, M | 1 |
| Miskolczi, G | 1 |
| Seprényi, G | 2 |
| Kaszaki, J | 2 |
| Kohr, MJ | 1 |
| Murphy, E | 1 |
| Végh, Á | 2 |
| Naryzhnaya, NV | 1 |
| Maslov, LN | 1 |
| Tsibulnikov, SY | 1 |
| Prokudina, ES | 1 |
| Lishmanov, YB | 1 |
| Charan, K | 1 |
| Zaman, J | 1 |
| Hausenloy, DJ | 1 |
| Botker, HE | 1 |
| Engstrom, T | 1 |
| Erlinge, D | 1 |
| Heusch, G | 1 |
| Ibanez, B | 1 |
| Kloner, RA | 1 |
| Ovize, M | 1 |
| Valle Raleigh, J | 1 |
| Mauro, AG | 1 |
| Devarakonda, T | 1 |
| Marchetti, C | 1 |
| He, J | 1 |
| Kim, E | 1 |
| Filippone, S | 1 |
| Das, A | 1 |
| Toldo, S | 1 |
| Abbate, A | 1 |
| Salloum, FN | 1 |
| Merx, MW | 1 |
| Shiva, S | 5 |
| Schmitz, J | 1 |
| Becher, S | 1 |
| Klare, JP | 1 |
| Steinhoff, HJ | 1 |
| Goedecke, A | 1 |
| Schrader, J | 1 |
| Gladwin, MT | 5 |
| Sinha, SS | 1 |
| McNulty, PH | 1 |
| Scott, S | 1 |
| Kehoe, V | 1 |
| Kozak, M | 1 |
| Sinoway, LI | 1 |
| Li, J | 1 |
| Tsikas, D | 1 |
| Rossi, R | 1 |
| Gandhi, C | 1 |
| Upaganalawar, A | 1 |
| Balaraman, R | 1 |
| Jung, C | 1 |
| Weitzberg, E | 1 |
| Lim, CC | 1 |
| Bryan, NS | 2 |
| Jain, M | 1 |
| Garcia-Saura, MF | 1 |
| Sawyer, DB | 1 |
| Handy, DE | 1 |
| Loscalzo, J | 1 |
| Liao, R | 1 |
| Milano, G | 1 |
| Corno, AF | 1 |
| Samaja, M | 1 |
| Morel, S | 1 |
| Vassalli, G | 1 |
| von Segesser, LK | 1 |
| Iliodromitis, EK | 2 |
| Andreadou, I | 2 |
| Prokovas, E | 1 |
| Zoga, A | 2 |
| Farmakis, D | 2 |
| Fotopoulou, T | 1 |
| Ioannidis, K | 1 |
| Paraskevaidis, IA | 1 |
| Kremastinos, DT | 2 |
| Raphael, J | 1 |
| Gozal, Y | 1 |
| Navot, N | 1 |
| Zuo, Z | 1 |
| Di Filippo, C | 1 |
| Monopoli, A | 1 |
| Ongini, E | 1 |
| Perretti, M | 1 |
| D'Amico, M | 1 |
| Wang, E | 1 |
| Feng, Y | 1 |
| Zhang, M | 1 |
| Zou, L | 1 |
| Li, Y | 1 |
| Buys, ES | 1 |
| Huang, P | 1 |
| Brouckaert, P | 1 |
| Chao, W | 1 |
| Condit, ME | 1 |
| Aragón, JP | 1 |
| Moody, BF | 1 |
| Hood, RL | 1 |
| Sindler, AL | 1 |
| Gundewar, S | 2 |
| Seals, DR | 1 |
| Barouch, LA | 1 |
| Bezzerides, V | 1 |
| Rosenzweig, A | 1 |
| Juhász, L | 1 |
| Nyeso, E | 1 |
| Song, T | 1 |
| Lv, LY | 1 |
| Xu, J | 1 |
| Tian, ZY | 1 |
| Cui, WY | 1 |
| Wang, QS | 1 |
| Qu, G | 1 |
| Shi, XM | 1 |
| Neye, N | 1 |
| Enigk, F | 1 |
| Habazettl, H | 1 |
| Plesnila, N | 1 |
| Kuppe, H | 1 |
| Kuebler, WM | 1 |
| Pisarenko, OI | 1 |
| Serebryakova, LI | 1 |
| Pelogeykina, YA | 1 |
| Studneva, IM | 1 |
| Khatri, DN | 1 |
| Tskitishvili, OV | 1 |
| Bespalova, ZhD | 1 |
| Az'muko, AA | 1 |
| Sidorova, MV | 1 |
| Pal'keeva, ME | 1 |
| Demerouti, E | 1 |
| Aggeli, IK | 1 |
| Gaitanaki, C | 1 |
| Beis, I | 1 |
| Anastasiou-Nana, M | 1 |
| Maczewski, M | 1 |
| Beresewicz, A | 1 |
| Sharma, M | 1 |
| Ganguly, NK | 1 |
| Chaturvedi, G | 1 |
| Thingnam, SK | 1 |
| Majumdar, S | 1 |
| Suri, RK | 1 |
| Webb, A | 1 |
| Bond, R | 1 |
| McLean, P | 1 |
| Uppal, R | 1 |
| Benjamin, N | 1 |
| Ding, HL | 1 |
| Zhu, HF | 1 |
| Dong, JW | 1 |
| Zhu, WZ | 1 |
| Yang, WW | 1 |
| Yang, HT | 1 |
| Zhou, ZN | 1 |
| Di Napoli, P | 2 |
| Taccardi, AA | 1 |
| Grilli, A | 2 |
| De Lutiis, MA | 1 |
| Barsotti, A | 2 |
| Felaco, M | 2 |
| De Caterina, R | 2 |
| Kuralay, F | 1 |
| Altekin, E | 1 |
| Yazlar, AS | 1 |
| Onvural, B | 1 |
| Goldeli, O | 1 |
| Larche, J | 1 |
| Lancel, S | 1 |
| Hassoun, SM | 1 |
| Favory, R | 1 |
| Decoster, B | 1 |
| Marchetti, P | 1 |
| Chopin, C | 1 |
| Neviere, R | 1 |
| De Gennaro Colonna, V | 1 |
| Bonomo, S | 1 |
| Ferrario, P | 1 |
| Bianchi, M | 1 |
| Berti, M | 1 |
| Guazzi, M | 1 |
| Manfredi, B | 1 |
| Muller, EE | 1 |
| Berti, F | 1 |
| Rossoni, G | 1 |
| Davani, S | 1 |
| Vergely, C | 1 |
| Royer, B | 1 |
| Bouhaddi, M | 1 |
| Reyssie, H | 1 |
| Rochette, L | 1 |
| Kantelip, JP | 1 |
| Sack, MN | 2 |
| Greer, JJ | 1 |
| Duranski, M | 1 |
| Ringwood, LA | 1 |
| Burwell, L | 1 |
| Wang, X | 1 |
| MacArthur, PH | 1 |
| Shoja, A | 1 |
| Raghavachari, N | 1 |
| Brookes, PS | 1 |
| Chen, CH | 1 |
| Liu, K | 1 |
| Chan, JY | 1 |
| Elrod, JW | 1 |
| Ji, SY | 1 |
| Schwartz, DR | 1 |
| Masini, E | 1 |
| Lupini, M | 1 |
| Mugnai, L | 1 |
| Raspanti, S | 1 |
| Mannaioni, PF | 1 |
| Zweier, JL | 1 |
| Wang, P | 1 |
| Samouilov, A | 1 |
| Kuppusamy, P | 1 |
| van Jaarsveld, H | 1 |
| Schulenburg, DH | 1 |
| Kouretas, PC | 1 |
| Kim, YD | 1 |
| Cahill, PA | 1 |
| Myers, AK | 1 |
| To, LN | 1 |
| Wang, YN | 1 |
| Sitzmann, JV | 1 |
| Hannan, RL | 1 |
| Parikh, V | 2 |
| Singh, M | 2 |
| Ma, XL | 1 |
| Gao, F | 1 |
| Liu, GL | 1 |
| Lopez, BL | 1 |
| Christopher, TA | 1 |
| Fukuto, JM | 1 |
| Wink, DA | 1 |
| Shen, JG | 1 |
| Quo, XS | 1 |
| Jiang, B | 1 |
| Li, M | 1 |
| Xin, W | 1 |
| Zhao, BL | 1 |
| Hayakawa, M | 1 |
| Ito, T | 1 |
| Osanai, H | 1 |
| Harada, M | 1 |
| Numaguchi, Y | 1 |
| Mokuno, S | 1 |
| Murase, K | 1 |
| Toki, Y | 1 |
| Okumura, K | 1 |
| Hayakawa, T | 1 |
| Zhai, P | 1 |
| Eurell, TE | 1 |
| Cotthaus, R | 1 |
| Jeffery, EH | 1 |
| Bahr, JM | 1 |
| Gross, DR | 1 |
| Hung, LM | 1 |
| Chen, JK | 1 |
| Lee, RS | 1 |
| Liang, HC | 1 |
| Su, MJ | 1 |
| Antonio Taccardi, A | 1 |
| Spina, R | 1 |
| Johnson, G | 2 |
| Tsao, PS | 1 |
| Mulloy, D | 1 |
| Lefer, AM | 2 |
| Tsao, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518] | 250 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | |||
| The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress[NCT00250185] | Phase 1 | 135 participants | Interventional | 2005-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for nitrites and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Mechanisms of the protective effects of nitrate and nitrite in cardiovascular and metabolic diseases.
Topics: Animals; Blood Pressure; Diabetes Mellitus; Endothelium, Vascular; Humans; Hypertension, Pulmonary; | 2020 |
Nitrite and myocardial ischaemia reperfusion injury. Where are we now?
Topics: Cardiotonic Agents; Clinical Trials as Topic; Humans; Myocardial Reperfusion Injury; Nitrites | 2021 |
Nitrite-Nitric Oxide Signaling and Cardioprotection.
Topics: Animals; Cytoprotection; Humans; Ischemic Preconditioning, Myocardial; Mitochondria, Heart; Myocardi | 2017 |
[New strategies in cardioprotection during acute myocardial infarction: Impact of hypoxic nitrate-nitrite-NO signaling].
Topics: Animals; Humans; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; Nitra | 2013 |
Nitroglycerine and sodium trioxodinitrate: from the discovery to the preconditioning effect.
Topics: Animals; Cardiovascular Agents; History, 19th Century; History, 20th Century; Humans; Myocardial Rep | 2013 |
Nitrite in organ protection.
Topics: Animals; Cytoprotection; Humans; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitrites; Pr | 2014 |
Myocardial protection by nitrite: evidence that this reperfusion therapeutic will not be lost in translation.
Topics: Animals; Clinical Trials as Topic; Cytoprotection; Hemoglobins; Humans; Myocardial Infarction; Myoca | 2008 |
Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function.
Topics: Animals; Cytoprotection; Electron Transport Complex I; Humans; Mitochondria, Heart; Myocardial Reper | 2009 |
Myocardial protection by nitrite.
Topics: Animals; Cytoprotection; Homeostasis; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; | 2009 |
NO generation from inorganic nitrate and nitrite: Role in physiology, nutrition and therapeutics.
Topics: Animals; Humans; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitri | 2009 |
Emerging role of nitrite in myocardial protection.
Topics: Animals; Cardiovascular Diseases; Cytoprotection; Homeostasis; Humans; Myocardial Reperfusion Injury | 2009 |
Targeting the mitochondria to augment myocardial protection.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Drug Delivery Systems; Homeostasis; Humans; Is | 2008 |
63 other studies available for nitrites and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats.
Topics: Animals; Female; Male; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitrites; Progesterone | 2023 |
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dyslipidemias; Heart; Insulin Resistance; Male; | 2020 |
Post-infarct morphine treatment reduces apoptosis and myofibroblast density in a rat model of cardiac ischemia-reperfusion.
Topics: Analgesics, Opioid; Animals; Antioxidants; Apoptosis; Coronary Vessels; Fibroblasts; Gelatinases; Li | 2020 |
S-nitrosation of calpains is associated with cardioprotection in myocardial I/R injury.
Topics: Animals; Calpain; Cell Line; Male; Mice, Inbred C57BL; Mitochondria; Myocardial Infarction; Myocardi | 2017 |
Short-term consumption of Ilex paraguariensis extracts protects isolated hearts from ischemia/reperfusion injury and contradicts exercise-mediated cardioprotection.
Topics: Animals; Blood Pressure; Glutathione; Heart; Ilex paraguariensis; Lipid Peroxidation; Male; Myocardi | 2017 |
Involvement of atrial natriuretic peptide in abrogated cardioprotective effect of ischemic preconditioning in ovariectomized rat heart.
Topics: Animals; Atrial Natriuretic Factor; Cardiotonic Agents; Creatine Kinase, MB Form; Female; Ischemic P | 2018 |
The GTN patch: a simple and effective new approach to cardioprotection?
Topics: Administration, Cutaneous; Animals; Blood Pressure; Disease Models, Animal; Male; Mice, Inbred C57BL | 2018 |
Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection.
Topics: Animals; Aorta; Cardiomegaly; Glutathione; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Repe | 2018 |
Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites.
Topics: Administration, Inhalation; Animals; Brain; Feasibility Studies; Freezing; Half-Life; Kidney; Lung; | 2018 |
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, A | 2013 |
Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.
Topics: Animals; Cardiotonic Agents; Carrier Proteins; Disease Models, Animal; Enzyme Activation; Gene Expre | 2013 |
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity.
Topics: Animals; Arginase; Arginine; Biological Transport, Active; Cardiotonic Agents; Enzyme Inhibitors; Er | 2013 |
[Mechanisms of coronary flow recovery in the isolated heart during reperfusion with cardioprotective liposomal emoxipin form].
Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Circulation; Heart; In Vitro Techniqu | 2013 |
Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved?
Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, | 2015 |
[INVOLVEMENT OF NO-SYNTHASE IN THE INFARCT REDUCING EFFECT OF CONTINUOUS CHRONIC NORMOBARTC HYPOXTA].
Topics: Animals; Hypoxia; Ischemic Preconditioning, Myocardial; Isothiuronium; Male; Myocardial Infarction; | 2015 |
Role of atrial natriuretic peptide in ischemic preconditioning-induced cardioprotection in the diabetic rat heart.
Topics: Alloxan; Animals; Atrial Natriuretic Factor; Blood Glucose; Diabetes Mellitus, Experimental; Drug Ev | 2016 |
Effect of fetal hypothyroidism on tolerance to ischemia-reperfusion injury in aged male rats: Role of nitric oxide.
Topics: Aging; Animals; bcl-2-Associated X Protein; Congenital Hypothyroidism; Creatine Kinase; L-Lactate De | 2016 |
Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations.
Topics: Adenosine; Cardiotonic Agents; Clinical Trials as Topic; Combined Modality Therapy; Coronary Vessels | 2017 |
Reperfusion therapy with recombinant human relaxin-2 (Serelaxin) attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury via eNOS-dependent mechanism.
Topics: Animals; Cardiovascular Agents; Caspase 1; Cells, Cultured; Disease Models, Animal; Inflammasomes; M | 2017 |
Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury.
Topics: Aconitate Hydratase; Animals; Cell Respiration; Cell Survival; Heme; In Vitro Techniques; Male; Mice | 2008 |
Nitrite consumption in ischemic rat heart catalyzed by distinct blood-borne and tissue factors.
Topics: Allopurinol; Animals; Catalysis; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Glucose; G | 2008 |
Letter by Tsikas and Rossi regarding article, "Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction".
Topics: Animals; Apoptosis; Cardiotonic Agents; Combined Modality Therapy; Cytoprotection; Dogs; Erythrocyte | 2009 |
Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arrhythmias, Car | 2009 |
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Enzyme Inhibitors; Heart Rate; Male; Myoca | 2010 |
Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms.
Topics: Animals; Antioxidants; Ascorbic Acid; Creatine Kinase; Disease Models, Animal; Female; Glutathione; | 2009 |
Daily reoxygenation decreases myocardial injury and improves post-ischaemic recovery after chronic hypoxia.
Topics: Animals; Body Weight; Chronic Disease; Hematocrit; Hemoglobins; Hypoxia; Male; Myocardial Infarction | 2010 |
Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation.
Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Hemodynamics; Hypercholesterolemia; | 2010 |
Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling.
Topics: Anesthetics; Animals; Blood Glucose; Blood Pressure; Creatine Kinase, MB Form; Glucose; Heart; Heart | 2010 |
The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse.
Topics: Animals; Cardiotonic Agents; Heme Oxygenase-1; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inh | 2010 |
Toll-like receptor 4 signaling confers cardiac protection against ischemic injury via inducible nitric oxide synthase- and soluble guanylate cyclase-dependent mechanisms.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Echocardiography; Electrocardiography; Guanylate Cyc | 2011 |
Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols.
Topics: Adolescent; Adult; Animals; Enzyme Activation; Exercise; Humans; Male; Mice; Mice, Knockout; Myocard | 2011 |
Saying yes to exercise and NO to cardiac injury.
Topics: Adolescent; Adult; Animals; Enzyme Activation; Exercise; Humans; Male; Mice; Mice, Knockout; Myocard | 2011 |
Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion?
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels | 2011 |
Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia-reperfusion injury: role of AMP-activated protein kinase pathway.
Topics: AMP-Activated Protein Kinases; Anesthetics, Inhalation; Animals; Diet, High-Fat; Ischemic Preconditi | 2011 |
Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function.
Topics: Administration, Inhalation; Animals; Cardiac Output; Cardiotonic Agents; Guanylate Cyclase; Male; Mo | 2012 |
In vivo reduction of reperfusion injury to the heart with apelin-12 peptide in rats.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Creatine Kinase, MB Form; Heart Ventricles; Intercellul | 2011 |
Ovariectomy reinstates the infarct size-limiting effect of postconditioning in female rabbits.
Topics: Animals; Coronary Vessels; Estradiol; Female; Hemodynamics; Ischemic Postconditioning; Mitogen-Activ | 2013 |
Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radicals; G | 2003 |
Release of pro-inflammatory mediators during myocardial ischemia/reperfusion in coronary artery bypass graft surgery.
Topics: Aged; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Biomarkers; CD4 Antigens; Cell Adhesion | 2003 |
Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage.
Topics: Animals; Cardiotonic Agents; Humans; Hydrogen-Ion Concentration; Male; Myocardial Ischemia; Myocardi | 2004 |
Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Guanidines; Hypoxia; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion | 2005 |
Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts.
Topics: Animals; Blotting, Western; Capillary Permeability; Creatine Kinase; Drug Administration Schedule; F | 2005 |
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidine.
Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Huma | 2006 |
Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality.
Topics: Animals; Bronchoalveolar Lavage Fluid; Caspases; Cyclosporine; Disease Models, Animal; Immunosuppres | 2006 |
Asymmetric dimethylarginine (ADMA) induces vascular endothelium impairment and aggravates post-ischemic ventricular dysfunction in rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Endothelium, Vascular; Enzy | 2007 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inh | 2007 |
Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer.
Topics: Aconitate Hydratase; Administration, Oral; Animals; Cytochromes c; Cytoprotection; Electron Transpor | 2007 |
Anesthetic preconditioning confers acute cardioprotection via up-regulation of manganese superoxide dismutase and preservation of mitochondrial respiratory enzyme activity.
Topics: Adenosine Triphosphate; Anesthetics; Animals; Decanoic Acids; Hydroxy Acids; Ischemic Preconditionin | 2008 |
Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury.
Topics: Administration, Oral; Animals; Dietary Supplements; Drug Evaluation, Preclinical; Heme; Mice; Myocar | 2007 |
Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Arrhythmias, Cardiac; Chemical Fractionation; Coronary Circulation | 1995 |
Enzyme-independent formation of nitric oxide in biological tissues.
Topics: Animals; Electron Spin Resonance Spectroscopy; Female; Heme; Hydrogen-Ion Concentration; In Vitro Te | 1995 |
Dietary iron alters liver, erythrocyte and plasma antioxidant and nitrite levels, and also sensitizes the heart to ischemia/reperfusion.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Erythrocytes; Female; Glutathione Peroxidase; Heart; | 1997 |
Nonanticoagulant heparin prevents coronary endothelial dysfunction after brief ischemia-reperfusion injury in the dog.
Topics: Animals; Anticoagulants; Blood Coagulation; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascula | 1999 |
Possible role of cardiac mast cell degranulation and preservation of nitric oxide release in isolated rat heart subjected to ischaemic preconditioning.
Topics: Animals; Cell Degranulation; Creatine Kinase; Female; In Vitro Techniques; Ischemic Preconditioning, | 1999 |
Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Glutathione; Hemodynamics; Male; Myocardial Ischemia; | 1999 |
Chinonin, a novel drug against cardiomyocyte apoptosis induced by hypoxia and reoxygenation.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; Biomarkers; Cell Hypoxia; Cells, Cultured; DNA Fra | 2000 |
Simultaneous intravascular two-dimensional plus Doppler ultrasound is useful for evaluation of postischemic vasodilatation: plasm NOx - levels determined by the Griess method may not reflect the extent of postischemic NO-induced vasodilatation.
Topics: Animals; Blood Pressure; Cardiology; Coronary Vessels; Dogs; Echocardiography; Enzyme Inhibitors; Fe | 2000 |
Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats.
Topics: Animals; Calcium; Coloring Agents; Coronary Circulation; Estradiol; Female; In Vitro Techniques; Mic | 2000 |
Possible role of nitric oxide and mast cells in endotoxin-induced cardioprotection.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Canavanine; Cardiovascular Diseases; Cell | 2001 |
Beneficial effects of astringinin, a resveratrol analogue, on the ischemia and reperfusion damage in rat heart.
Topics: Animals; Antioxidants; Free Radical Scavengers; Heart; Hemodynamics; L-Lactate Dehydrogenase; Male; | 2001 |
Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts.
Topics: Analysis of Variance; Animals; Blotting, Western; Capillary Permeability; Creatine Kinase; Enzyme In | 2001 |
Cardioprotective effects of acidified sodium nitrite in myocardial ischemia with reperfusion.
Topics: Animals; Blood Pressure; Cats; Coronary Disease; Creatine Kinase; Heart; Heart Rate; Male; Myocardia | 1990 |
Synergism between superoxide dismutase and sodium nitrite in cardioprotection following ischemia and reperfusion.
Topics: Animals; Cats; Coronary Disease; Creatine Kinase; Drug Synergism; Drug Therapy, Combination; Male; M | 1990 |