nitrites has been researched along with Infarction, Middle Cerebral Artery in 17 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subacute sodium nitrite infusions prevented delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage." | 3.73 | Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. ( Dejam, A; Gladwin, MT; Grimes, G; Oldfield, EH; Pluta, RM, 2005) |
| "Daily intake of green tea catechins efficiently protects the penumbra from irreversible damage due to cerebral ischemia, and consequent neurologic deficits." | 3.72 | Protective effects of green tea catechins on cerebral ischemic damage. ( Ikeda, M; Suzuki, M; Tabuchi, M; Tomita, T; Umegaki, K, 2004) |
| "All animals underwent right middle cerebral artery occlusion (MCAO) for 2 h." | 1.38 | Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats. ( Chen, S; Dong, H; Hou, L; Hu, S; Wang, S; Xiong, L; Zhang, H; Zhang, J, 2012) |
| " Among the causative factors of BBB disruption are accelerating peroxynitrite formation and the resultant decreased bioavailability of nitric oxide (NO)." | 1.38 | The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke. ( Dhammu, TS; Gilg, AG; Khan, M; Sakakima, H; Shunmugavel, A; Singh, AK; Singh, I, 2012) |
| "The neuronal damage following cerebral ischemia is a serious risk to stroke patients." | 1.37 | Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats. ( Ji, A; Liang, H; Liu, P; Song, S; Wang, Y, 2011) |
| "Focal cerebral ischemia was induced in two sets of animals by permanent middle cerebral artery occlusion." | 1.35 | The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. ( Aral, E; Arslan, OC; Durmaz, R; Kanbak, G; Kartkaya, K; Ozden, H; Uzuner, K, 2008) |
| "Rosiglitazone or 15d-PGJ2 were administered to rats 10 mins or 2 h after permanent middle cerebral artery occlusion (MCAO)." | 1.33 | Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. ( Boscá, L; Cárdenas, A; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pereira, MP; Serena, J; Vivancos, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Rajput, R | 1 |
| Chavda, V | 1 |
| Patel, SS | 1 |
| Barreto, GE | 1 |
| Ashraf, GM | 1 |
| Jin, YC | 1 |
| Lee, H | 1 |
| Kim, SW | 1 |
| Kim, ID | 1 |
| Lee, HK | 1 |
| Lee, Y | 1 |
| Han, PL | 1 |
| Lee, JK | 1 |
| Dohare, P | 1 |
| Garg, P | 1 |
| Jain, V | 1 |
| Nath, C | 1 |
| Ray, M | 1 |
| Choe, CU | 1 |
| Lewerenz, J | 1 |
| Fischer, G | 1 |
| Uliasz, TF | 1 |
| Espey, MG | 1 |
| Hummel, FC | 1 |
| King, SB | 1 |
| Schwedhelm, E | 1 |
| Böger, RH | 1 |
| Gerloff, C | 1 |
| Hewett, SJ | 1 |
| Magnus, T | 1 |
| Donzelli, S | 1 |
| Ahn, SK | 1 |
| Hong, S | 1 |
| Park, YM | 1 |
| Lee, WT | 1 |
| Park, KA | 1 |
| Lee, JE | 1 |
| Liang, H | 1 |
| Liu, P | 1 |
| Wang, Y | 1 |
| Song, S | 1 |
| Ji, A | 1 |
| Hu, S | 1 |
| Dong, H | 1 |
| Zhang, H | 1 |
| Wang, S | 1 |
| Hou, L | 1 |
| Chen, S | 1 |
| Zhang, J | 1 |
| Xiong, L | 1 |
| Ruscher, K | 1 |
| Inácio, AR | 1 |
| Valind, K | 1 |
| Rowshan Ravan, A | 1 |
| Kuric, E | 1 |
| Wieloch, T | 1 |
| Khan, M | 1 |
| Dhammu, TS | 1 |
| Sakakima, H | 1 |
| Shunmugavel, A | 1 |
| Gilg, AG | 1 |
| Singh, AK | 1 |
| Singh, I | 1 |
| Ding-Zhou, L | 1 |
| Marchand-Verrecchia, C | 1 |
| Croci, N | 1 |
| Plotkine, M | 1 |
| Margaill, I | 1 |
| Ohtaki, H | 1 |
| Takaki, A | 1 |
| Yin, L | 1 |
| Dohi, K | 1 |
| Nakamachi, T | 1 |
| Matsunaga, M | 1 |
| Horai, R | 1 |
| Asano, M | 1 |
| Iwakura, Y | 1 |
| Shioda, S | 1 |
| Shirhan, MD | 1 |
| Moochhala, SM | 1 |
| Ng, PY | 1 |
| Lu, J | 1 |
| Ng, KC | 1 |
| Teo, AL | 1 |
| Yap, E | 1 |
| Ng, I | 1 |
| Hwang, P | 1 |
| Lim, T | 1 |
| Sitoh, YY | 1 |
| Rumpel, H | 1 |
| Jose, R | 1 |
| Ling, E | 1 |
| Suzuki, M | 1 |
| Tabuchi, M | 1 |
| Ikeda, M | 1 |
| Umegaki, K | 1 |
| Tomita, T | 1 |
| Pluta, RM | 1 |
| Dejam, A | 1 |
| Grimes, G | 1 |
| Gladwin, MT | 1 |
| Oldfield, EH | 1 |
| Pereira, MP | 1 |
| Hurtado, O | 1 |
| Cárdenas, A | 1 |
| Boscá, L | 1 |
| Castillo, J | 1 |
| Dávalos, A | 1 |
| Vivancos, J | 1 |
| Serena, J | 1 |
| Lorenzo, P | 1 |
| Lizasoain, I | 1 |
| Moro, MA | 1 |
| Durmaz, R | 1 |
| Ozden, H | 1 |
| Kanbak, G | 1 |
| Aral, E | 1 |
| Arslan, OC | 1 |
| Kartkaya, K | 1 |
| Uzuner, K | 1 |
| Serteser, M | 1 |
| Ozben, T | 1 |
| Gümüşlü, S | 1 |
| Balkan, S | 1 |
| Balkan, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2, Multi-Center, Open-label, Randomized, Parallel-Dose Study to Determine the Safety and Efficacy of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension (PAH)[NCT01725256] | Phase 2 | 29 participants (Actual) | Interventional | 2012-11-30 | Terminated (stopped due to Terminated early dt to acquisition of Sponsor and change in corporate priorities) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 other studies available for nitrites and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Efonidipine Exerts Cerebroprotective Effect by Down-regulation of TGF-β/SMAD-2-Dependent Signaling Pathway in Diabetic Rats.
Topics: Acetylcholinesterase; Animals; Brain; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dih | 2021 |
Intranasal Delivery of RGD Motif-Containing Osteopontin Icosamer Confers Neuroprotection in the Postischemic Brain via αvβ3 Integrin Binding.
Topics: Administration, Intranasal; Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Brain; Brain Isc | 2016 |
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea | 2008 |
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Topics: Animals; Blood Pressure; Brain Infarction; Cells, Cultured; Dinoprost; Disease Models, Animal; Dose- | 2009 |
Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase.
Topics: Agmatine; Analysis of Variance; Animals; Calcium-Binding Proteins; Cell Hypoxia; Cell Line, Transfor | 2011 |
Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats.
Topics: Alkaloids; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Leonurus; Male; M | 2011 |
Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats.
Topics: Adenosine; Analysis of Variance; Animals; Brain Infarction; Diffusion Magnetic Resonance Imaging; Di | 2012 |
Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke.
Topics: Animals; CD11b Antigen; Cytokines; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Infl | 2012 |
The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Carrier Proteins; Disease Models, Animal; E-Select | 2012 |
L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Ischemia; Disease Models, Animal; Enzyme | 2002 |
Suppression of oxidative stress after transient focal ischemia in interleukin-1 knock out mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Brain; Cattle; Deoxyguanosine; Infarction, Middle Cerebral Art | 2003 |
Spermine reduces infarction and neurological deficit following a rat model of middle cerebral artery occlusion: a magnetic resonance imaging study.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Brain Infarction; Brain Mapping; D | 2004 |
Protective effects of green tea catechins on cerebral ischemic damage.
Topics: Animals; Brain Ischemia; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, | 2004 |
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.
Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infarction, Middle Cerebral Artery; Infusions | 2005 |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Disease Models, Animal; Drug Administration Sch | 2006 |
The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cerebral Cortex; Cysteine | 2008 |
Biochemical evidence of crossed cerebellar diaschisis in terms of nitric oxide indicators and lipid peroxidation products in rats during focal cerebral ischemia.
Topics: Afferent Pathways; Animals; Cerebellum; Cerebral Cortex; Cyclic GMP; Dominance, Cerebral; Infarction | 2001 |