Page last updated: 2024-10-19

nitrites and Impotence

nitrites has been researched along with Impotence in 9 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"Aging is associated with erectile dysfunction (ED), in which nitric oxide synthase (NOS) activity and NO bioavailability are reduced due to deficiencies of NOS cofactor (tetrahydrobiopterin, BH(4)) and substrate (L-arginine)."7.80L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats. ( Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D, 2014)
"Sildenafil is the most used treatment of erectile dysfunction, however a large part of patients do not respond to therapy."5.46Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy. ( Azevedo, AMM; Brites-Anselmi, G; Coeli-Lacchini, FB; de Almeida Belo, V; de Andrade, MF; Hirsch, E; Lacchini, R; Molina, CAF; Pinheiro, LC; Tanus-Santos, JE; Tucci, S, 2017)
"Aging is associated with erectile dysfunction (ED), in which nitric oxide synthase (NOS) activity and NO bioavailability are reduced due to deficiencies of NOS cofactor (tetrahydrobiopterin, BH(4)) and substrate (L-arginine)."3.80L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats. ( Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D, 2014)
" However, it is not known whether low NO bioavailability and oxidative stress affect the responsiveness of ED patients to sildenafil."2.78Low nitric oxide bioavailability is associated with better responses to sildenafil in patients with erectile dysfunction. ( Jordão, AA; Lacchini, R; Martins, AC; Muniz, JJ; Nobre, YT; Sertório, JT; Tanus-Santos, JE; Tucci, S, 2013)
"Hypertension is a risk factor for erectile dysfunction (ED) and both conditions are associated with oxidative stress."1.56Treatment with nitrite prevents reactive oxygen species generation in the corpora cavernosa and restores intracavernosal pressure in hypertensive rats. ( Carneiro, FS; da Silva, CBP; do Vale, GT; Gonzaga, NA; Leite, LN; Pinheiro, LC; Tanus-Santos, JE; Tirapelli, CR, 2020)
"Dyslipidemia was showed by 52."1.48Relationship Between Erectile Dysfunction, Diabetes and Dyslipidemia in Hypertensive-Treated Men. ( Lahera, V; Lopez-Farre, AJ; Prieto, R; Puigvert, A; Rodriguez-Pardo, JM; Segura, A; Zamorano-Leon, JJ, 2018)
"Sildenafil is the most used treatment of erectile dysfunction, however a large part of patients do not respond to therapy."1.46Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy. ( Azevedo, AMM; Brites-Anselmi, G; Coeli-Lacchini, FB; de Almeida Belo, V; de Andrade, MF; Hirsch, E; Lacchini, R; Molina, CAF; Pinheiro, LC; Tanus-Santos, JE; Tucci, S, 2017)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Liu, G1
Liu, J1
Kong, X1
Xiong, WJ1
Jiang, R1
Gonzaga, NA1
do Vale, GT1
da Silva, CBP1
Pinheiro, LC2
Leite, LN1
Carneiro, FS1
Tanus-Santos, JE3
Tirapelli, CR1
Azevedo, AMM1
Brites-Anselmi, G1
de Almeida Belo, V1
Coeli-Lacchini, FB1
Molina, CAF1
de Andrade, MF1
Tucci, S2
Hirsch, E1
Lacchini, R2
Zamorano-Leon, JJ1
Segura, A1
Lahera, V1
Rodriguez-Pardo, JM1
Prieto, R1
Puigvert, A1
Lopez-Farre, AJ1
Muniz, JJ1
Sertório, JT1
Jordão, AA1
Nobre, YT1
Martins, AC1
Un, O1
Yilmaz, D1
Bayatli, N1
Kaya, E1
Gur, S1
Dhaunsi, GS1
Yousif, M1
Makki, B1
Akhtar, S1
Benter, IF1
Bivalacqua, TJ1
Usta, MF1
Champion, HC1
Adams, D1
Namara, DB1
Abdel-Mageed, AB1
Kadowitz, PJ1
Hellstrom, WJ1
Tuncayengin, A1
Biri, H1
Onaran, M1
Sen, I1
Tuncayengin, O1
Polat, F1
Erbaş, D1
Bozkirli, I1

Trials

1 trial available for nitrites and Impotence

ArticleYear
Low nitric oxide bioavailability is associated with better responses to sildenafil in patients with erectile dysfunction.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:9

    Topics: Adult; Aged; Biological Availability; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glutathione;

2013

Other Studies

8 other studies available for nitrites and Impotence

ArticleYear
Effect of hypoandrogenism on expression of transient receptor potential vanilloid channels in rat penile corpus cavernosum and erectile function.
    The journal of sexual medicine, 2023, 08-25, Volume: 20, Issue:9

    Topics: Animals; Endothelial Cells; Erectile Dysfunction; Humans; Male; Nitric Oxide Synthase Type III; Nitr

2023
Treatment with nitrite prevents reactive oxygen species generation in the corpora cavernosa and restores intracavernosal pressure in hypertensive rats.
    Nitric oxide : biology and chemistry, 2020, 01-01, Volume: 94

    Topics: Animals; Antihypertensive Agents; Antioxidants; Erectile Dysfunction; Hypertension; Male; Nitrites;

2020
Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy.
    Nitric oxide : biology and chemistry, 2017, Dec-01, Volume: 71

    Topics: Amidohydrolases; Arginine; Biomarkers; Erectile Dysfunction; Humans; Male; Nitrites; Phosphodiestera

2017
Relationship Between Erectile Dysfunction, Diabetes and Dyslipidemia in Hypertensive-Treated Men.
    Urology journal, 2018, 11-17, Volume: 15, Issue:6

    Topics: Age Factors; Comorbidity; Diabetes Mellitus; Dyslipidemias; Erectile Dysfunction; Humans; Hypertensi

2018
L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats.
    The aging male : the official journal of the International Society for the Study of the Aging Male, 2014, Volume: 17, Issue:4

    Topics: Aging; Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Erectile Dysfunction; Male;

2014
Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.
    BioMed research international, 2017, Volume: 2017

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin I; Animals; Cyclic GMP; Diabetes Mellitus, Experime

2017
Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.
    The Journal of urology, 2003, Volume: 169, Issue:5

    Topics: Animals; beta-Galactosidase; Diabetes Mellitus, Experimental; Erectile Dysfunction; Gene Transfer Te

2003
Cavernosal tissue nitrite, nitrate, malondialdehyde and glutathione levels in diabetic and non-diabetic erectile dysfunction.
    International journal of andrology, 2003, Volume: 26, Issue:4

    Topics: Adult; Aged; Diabetes Complications; Erectile Dysfunction; Glutathione; Humans; Male; Malondialdehyd

2003