Page last updated: 2024-10-19

nitrites and Hypercholesterolemia

nitrites has been researched along with Hypercholesterolemia in 34 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.

Research Excerpts

ExcerptRelevanceReference
" We examined whether hypercholesterolemia inhibits vasculogenic effects of transplanted human circulating progenitor cells in ischemic tissue and whether L-arginine, a nitric oxide donor, might prevent impairment."7.76Impairment of human cell-based vasculogenesis in rats by hypercholesterolemia-induced endothelial dysfunction and rescue with L-arginine supplementation. ( Chan, V; Hazra, S; Kumarathasan, P; Mesana, TG; Price, J; Ruel, M; Sellke, FW; Suuronen, EJ; Veinot, JP; Vincent, R; Zhang, P; Zhang, Y, 2010)
"Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner."7.76Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. ( Aihara, K; Akaike, M; Dagvasumberel, M; Hirata, Y; Ishikawa, K; Iwase, T; Koshiba, K; Kusunose, K; Matsumoto, T; Niki, T; Sata, M; Soeki, T; Sumitomo-Ueda, Y; Taketani, Y; Tomita, N; Wakatsuki, T; Yagi, S; Yamada, H; Yamaguchi, K; Yoshida, S, 2010)
" The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production."7.74L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia. ( Haghjooy Javanmard, S; Monajemi, A; Nematbakhsh, M, 2008)
"In this study, plasma NO2- and NO3- (NOx-) levels were studied after lowering cholesterol with simvastatin in 26 outpatients with hypercholesterolemia (male, 9; female, 17; mean age, 59 +/- 12 years; cholesterol level > 220 mg/dl)."7.69Simvastatin increases plasma NO2- and NO3- levels in patients with hypercholesterolemia. ( Kuroiwa, A; Nakashima, Y; Tanaka, S; Tasaki, H; Toyokawa, Y; Yamashita, K; Yashiro, A, 1996)
"Hypercholesterolemia is a major risk factor for the development and progression of cardiovascular diseases including atherosclerosis."5.35Suppression of diet-induced hypercholesterolemia by scutellarin in rats. ( Chan, SW; Chen, SL; Cheng, HL; Guo, DJ; Li, Q; Wu, JH, 2009)
"We discovered that in the patients with chronic coronary heart disease (CHD) the mean value of nitrites was 18 +/- 0."4.79Nitrite plasma levels in acute and chronic coronary heart disease. ( Ferlito, S; Gallina, M, 1997)
" We examined whether hypercholesterolemia inhibits vasculogenic effects of transplanted human circulating progenitor cells in ischemic tissue and whether L-arginine, a nitric oxide donor, might prevent impairment."3.76Impairment of human cell-based vasculogenesis in rats by hypercholesterolemia-induced endothelial dysfunction and rescue with L-arginine supplementation. ( Chan, V; Hazra, S; Kumarathasan, P; Mesana, TG; Price, J; Ruel, M; Sellke, FW; Suuronen, EJ; Veinot, JP; Vincent, R; Zhang, P; Zhang, Y, 2010)
"Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner."3.76Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. ( Aihara, K; Akaike, M; Dagvasumberel, M; Hirata, Y; Ishikawa, K; Iwase, T; Koshiba, K; Kusunose, K; Matsumoto, T; Niki, T; Sata, M; Soeki, T; Sumitomo-Ueda, Y; Taketani, Y; Tomita, N; Wakatsuki, T; Yagi, S; Yamada, H; Yamaguchi, K; Yoshida, S, 2010)
"The impact of L-arginine on atherogenesis and its ability to prevent endothelial dysfunction have been studied extensively during the past years."3.74The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation. ( Haghjooyjavanmard, S; Mahmoodi, F; Monajemi, AR; Nematbakhsh, M, 2008)
" The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production."3.74L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia. ( Haghjooy Javanmard, S; Monajemi, A; Nematbakhsh, M, 2008)
" Forearm blood flow (FBF) during reactive hyperemia and after sublingual nitroglycerin (NTG) administration was measured by strain-gauge plethysmography."3.71Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women. ( Chayama, K; Higashi, Y; Kimura, M; Kodama, I; Nakagawa, K; Ohama, K; Sanada, M; Tsuda, M, 2002)
" We examined the hypothesis that HC may inhibit ischemia-induced angiogenesis by inhibition of EDNO in a rat model of unilateral hindlimb ischemia and that oral L-arginine supplementation, a substrate for NO synthase, may prevent HC-related impairment of angiogenesis."3.70Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. ( Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N, 2000)
"In this study, plasma NO2- and NO3- (NOx-) levels were studied after lowering cholesterol with simvastatin in 26 outpatients with hypercholesterolemia (male, 9; female, 17; mean age, 59 +/- 12 years; cholesterol level > 220 mg/dl)."3.69Simvastatin increases plasma NO2- and NO3- levels in patients with hypercholesterolemia. ( Kuroiwa, A; Nakashima, Y; Tanaka, S; Tasaki, H; Toyokawa, Y; Yamashita, K; Yashiro, A, 1996)
"Hypercholesterolemia is linked to endothelial dysfunction and enhancement of the endogenous inhibitor of NO synthase."2.71Effects of simvastatin and L-arginine on vasodilation, nitric oxide metabolites and endogenous NOS inhibitors in hypercholesterolemic subjects. ( Abdalla, DS; Bersch, D; Bertolami, MC; Faludi, AA; Pereira, EC; Salem, M, 2003)
"Hypertension was induced by L-N(G)-nitroarginine methyl ester (L-NAME) and hypercholesterolemia was induced by feeding rats with a diet containing 1% cholesterol."1.46Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms. ( Abd-Eldayem, AM; Abdel-Zaher, AO; El-Refaiy, AEM; Farghaly, HSM, 2017)
"Hypercholesterolemia is associated with decreased nitric oxide (NO) bioavailability and endothelial dysfunction, a phenomenon thought to have a major role in the altered cerebral blood flow evident in stroke."1.36Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice. ( Ahluwalia, A; Duchene, J; Hattori, N; Milsom, AB; Panayiotou, C; Urabe, T; Yamashiro, K, 2010)
"Hypercholesterolemia is a major risk factor for the development and progression of cardiovascular diseases including atherosclerosis."1.35Suppression of diet-induced hypercholesterolemia by scutellarin in rats. ( Chan, SW; Chen, SL; Cheng, HL; Guo, DJ; Li, Q; Wu, JH, 2009)
"Atherosclerosis is enhanced in arterial segments exposed to disturbed flow."1.35Beneficial effects of low doses of red wine consumption on perturbed shear stress-induced atherogenesis. ( Balestrieri, ML; Crimi, E; D'Armiento, FP; De Rosa, G; Lerman, LO; Napoli, C; Schiano, C; Servillo, L; Sica, V, 2008)
"Treatment with rosiglitazone enhanced PPARgamma expression, improved endothelium-dependent vasodilatation, preserved P-VASP, suppressed gp91phox and iNOS expression, reduced superoxide and total NOx production, and inhibited nitrotyrosine formation."1.32Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. ( Batinic-Haberle, I; Christopher, TA; Gao, E; Liu, HR; Lopez, BL; Ma, XL; Ohlstein, EH; Tao, L; Teng, ZP; Willette, RN; Yue, TL, 2003)
"In patients with >50% stenosis, NO(2)(-)/HDL-C was only shown to change significantly in relation to obstructive artery number (p=0."1.32Ratios of homocysteine and nitrite to high-density lipoprotein in coronary artery patients with the different degree of stenosis. ( Afrasyap, L; Oztürk, G, 2004)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (23.53)18.2507
2000's16 (47.06)29.6817
2010's9 (26.47)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Namwong, A1
Kumphune, S1
Seenak, P1
Chotima, R1
Nernpermpisooth, N1
Malakul, W1
Abdel-Zaher, AO1
Farghaly, HSM1
El-Refaiy, AEM1
Abd-Eldayem, AM1
Andrade, VL1
Sertório, JT1
Eleuterio, NM1
Tanus-Santos, JE1
Fernandes, KS1
Sandrim, VC1
Velmurugan, S1
Gan, JM1
Rathod, KS1
Khambata, RS1
Ghosh, SM1
Hartley, A1
Van Eijl, S1
Sagi-Kiss, V1
Chowdhury, TA1
Curtis, M1
Kuhnle, GG1
Wade, WG1
Ahluwalia, A2
Nematbakhsh, M2
Haghjooyjavanmard, S1
Mahmoodi, F1
Monajemi, AR1
Haghjooy Javanmard, S1
Monajemi, A1
Lundberg, JO1
Li, Q1
Wu, JH1
Guo, DJ1
Cheng, HL1
Chen, SL1
Chan, SW1
Iliodromitis, EK1
Andreadou, I1
Prokovas, E1
Zoga, A1
Farmakis, D1
Fotopoulou, T1
Ioannidis, K1
Paraskevaidis, IA1
Kremastinos, DT1
Suuronen, EJ1
Hazra, S1
Zhang, P1
Vincent, R1
Kumarathasan, P1
Zhang, Y1
Price, J1
Chan, V1
Sellke, FW1
Mesana, TG1
Veinot, JP1
Ruel, M1
Yagi, S1
Akaike, M1
Aihara, K1
Iwase, T1
Ishikawa, K1
Yoshida, S1
Sumitomo-Ueda, Y1
Kusunose, K1
Niki, T1
Yamaguchi, K1
Koshiba, K1
Hirata, Y2
Dagvasumberel, M1
Taketani, Y1
Tomita, N1
Yamada, H1
Soeki, T1
Wakatsuki, T1
Matsumoto, T1
Sata, M1
Yamashiro, K1
Milsom, AB1
Duchene, J1
Panayiotou, C1
Urabe, T1
Hattori, N1
Ozsoy, O2
Hacioglu, G2
Savcioglu, F2
Kucukatay, V2
Yargicoglu, P2
Agar, A2
Sanada, M1
Higashi, Y1
Nakagawa, K1
Tsuda, M1
Kodama, I1
Kimura, M1
Chayama, K1
Ohama, K1
Pereira, EC1
Bertolami, MC2
Faludi, AA1
Salem, M1
Bersch, D1
Abdalla, DS2
Tao, L1
Liu, HR1
Gao, E1
Teng, ZP1
Lopez, BL1
Christopher, TA1
Ma, XL1
Batinic-Haberle, I1
Willette, RN1
Ohlstein, EH1
Yue, TL1
Afrasyap, L1
Oztürk, G1
Rajamannan, NM1
Subramaniam, M1
Stock, SR1
Stone, NJ1
Springett, M1
Ignatiev, KI1
McConnell, JP1
Singh, RJ1
Bonow, RO1
Spelsberg, TC1
Taniguchi, J1
Honda, H1
Shibusawa, Y1
Iwata, T1
Notoya, Y1
Kremins'ka, IB1
Levyts'kyĭ, VA1
Napoli, C1
Balestrieri, ML1
Sica, V1
Lerman, LO1
Crimi, E1
De Rosa, G1
Schiano, C1
Servillo, L1
D'Armiento, FP1
Nakashima, Y2
Toyokawa, Y1
Tanaka, S2
Yamashita, K1
Yashiro, A2
Tasaki, H1
Kuroiwa, A2
Nanri, H1
Ikeda, M1
Ferlito, S3
Gallina, M3
Kang, BP1
Mehta, U1
Bansal, MP1
Minami, M1
Atarashi, K1
Ishiyama, A1
Goto, A1
Omata, M1
Kano, H2
Hayashi, T2
Sumi, D2
Esaki, T1
Asai, Y1
Thakur, NK2
Jayachandran, M1
Iguchi, A2
Catassi, S2
Bisicchia, A2
Di Salvo, M1
Di Salvo, MM1
Duan, J1
Murohara, T1
Ikeda, H1
Katoh, A1
Shintani, S1
Sasaki, K1
Kawata, H1
Yamamoto, N1
Imaizumi, T1
Rahman, MM1
Varghese, Z1
Moorhead, JF1
Moriel, P1
Pereira, IR1
Tsunekawa, T1
Matsui-Hirai, H1
Egashira, K1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Randomised, Placebo-controlled Parallel Study to Investigate the Influence of Dietary Nitrate on Skin Inflammation in Healthy Volunteers[NCT03183830]Phase 124 participants (Actual)Interventional2017-02-02Completed
Investigation of Dietary Nitrate Optimisation by Hyperuricaemia Stratification in Heart Failure[NCT03511248]Phase 292 participants (Anticipated)Interventional2018-06-01Active, not recruiting
Investigation of the Effect of Dietary Nitrate Treatment on Endothelial Function, Platelet Reactivity in Hypercholesterolemics Without Known Cardiovascular Disease or Atherosclerosis.[NCT01493752]Phase 169 participants (Actual)Interventional2011-08-31Completed
Rosuvastatin Affecting Aortic Valve Endothelium - RAAVE[NCT00114491]200 participants Observational2003-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrites and Hypercholesterolemia

ArticleYear
Nitrite plasma levels in acute and chronic coronary heart disease.
    Minerva cardioangiologica, 1997, Volume: 45, Issue:11

    Topics: Acute Disease; Aged; Chronic Disease; Coronary Disease; Female; Humans; Hypercholesterolemia; Hypert

1997

Trials

3 trials available for nitrites and Hypercholesterolemia

ArticleYear
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:1

    Topics: Adult; Atherosclerosis; Bacteria; Beta vulgaris; Blood Platelets; Diet; Double-Blind Method; Female;

2016
Effects of simvastatin and L-arginine on vasodilation, nitric oxide metabolites and endogenous NOS inhibitors in hypercholesterolemic subjects.
    Free radical research, 2003, Volume: 37, Issue:5

    Topics: Anticholesteremic Agents; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female;

2003
Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
    Circulation, 2001, Jul-24, Volume: 104, Issue:4

    Topics: Aged; Brachial Artery; Cyclic GMP; Diabetes Complications; Diabetes Mellitus; Endothelium, Vascular;

2001

Other Studies

30 other studies available for nitrites and Hypercholesterolemia

ArticleYear
Pineapple fruit improves vascular endothelial dysfunction, hepatic steatosis, and cholesterol metabolism in rats fed a high-cholesterol diet.
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Ananas; Animals; Antioxidants; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diet; Fatty Liver; Frui

2022
Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Animals; Blood Pressure; Creatinine; Diastole; Ginkgo biloba; Glutathione; Hypercholesterolemia; Hyp

2017
Simvastatin treatment increases nitrite levels in obese women: modulation by T(-786)C polymorphism of eNOS.
    Nitric oxide : biology and chemistry, 2013, Sep-01, Volume: 33

    Topics: Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Nitric Oxide Synthase Type III; Nitr

2013
The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation.
    Lipids in health and disease, 2008, Aug-02, Volume: 7

    Topics: Animals; Aorta; Apoptosis; Arginine; Atherosclerosis; Cell Count; Cholesterol; Dietary Supplements;

2008
L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia.
    Iranian biomedical journal, 2008, Volume: 12, Issue:3

    Topics: Animals; Arginine; Cholesterol; Dietary Supplements; Disease Models, Animal; Hypercholesterolemia; M

2008
Cardiovascular prevention by dietary nitrate and nitrite.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Diseases; Diet; Endothelium, Vascular; Humans; Hyp

2009
Suppression of diet-induced hypercholesterolemia by scutellarin in rats.
    Planta medica, 2009, Volume: 75, Issue:11

    Topics: Animals; Anticholesteremic Agents; Apigenin; Cholesterol; Disease Models, Animal; Drugs, Chinese Her

2009
Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation.
    Basic research in cardiology, 2010, Volume: 105, Issue:2

    Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Hemodynamics; Hypercholesterolemia;

2010
Impairment of human cell-based vasculogenesis in rats by hypercholesterolemia-induced endothelial dysfunction and rescue with L-arginine supplementation.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 139, Issue:1

    Topics: Animals; Arginine; Cytokines; Endothelial Cells; Endothelin-1; Extremities; Humans; Hypercholesterol

2010
Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.
    Journal of atherosclerosis and thrombosis, 2010, Feb-26, Volume: 17, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Anticholesteremic Agents; Azetidines; C-Reactive Pro

2010
Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:8

    Topics: Animals; Aorta; Apolipoproteins E; Cells, Cultured; Cilostazol; Cyclic GMP; Endothelin-1; Endotheliu

2010
The effect of sodium metabisulphite on active avoidance performance in hypercholesterolemic rats.
    Environmental toxicology, 2012, Volume: 27, Issue:8

    Topics: Animals; Antioxidants; Avoidance Learning; Cholesterol; Hippocampus; Hypercholesterolemia; Male; Nit

2012
The effect of sodium metabisulfite on visual evoked potentials in rats with hypercholesterolemia.
    Toxicology mechanisms and methods, 2011, Volume: 21, Issue:6

    Topics: Animals; Antioxidants; Brain; Cholesterol; Cholesterol, Dietary; Evoked Potentials, Visual; Hypercho

2011
Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:10

    Topics: Arteries; Blood Flow Velocity; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Estradiol;

2002
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
    Circulation, 2003, Dec-02, Volume: 108, Issue:22

    Topics: Animals; Antioxidants; Blood Vessels; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kin

2003
Ratios of homocysteine and nitrite to high-density lipoprotein in coronary artery patients with the different degree of stenosis.
    Vascular pharmacology, 2004, Volume: 41, Issue:3

    Topics: Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Constriction, Pathologic; Coronary A

2004
Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:6

    Topics: Animals; Anticholesteremic Agents; Aortic Valve; Atorvastatin; Blotting, Western; C-Reactive Protein

2005
Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia.
    Vascular pharmacology, 2005, Volume: 43, Issue:1

    Topics: Acetylcholine; Animals; Biological Factors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhib

2005
[Effect of the physical loadings of different intensity on atherogenesis in rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2007, Volume: 53, Issue:4

    Topics: Animals; Atherosclerosis; Femoral Artery; Hypercholesterolemia; Male; Nitrites; Physical Exertion; R

2007
Beneficial effects of low doses of red wine consumption on perturbed shear stress-induced atherogenesis.
    Heart and vessels, 2008, Volume: 23, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Atherosclerosis; Cells, Cultured; Disease Models, Anima

2008
Simvastatin increases plasma NO2- and NO3- levels in patients with hypercholesterolemia.
    Atherosclerosis, 1996, Nov-15, Volume: 127, Issue:1

    Topics: Administration, Oral; Anticholesteremic Agents; Cholesterol, LDL; Cholesterol, VLDL; Female; Follow-

1996
Plasma nitrite/nitrate level is inversely correlated with plasma low-density lipoprotein cholesterol level.
    Clinical cardiology, 1997, Volume: 20, Issue:4

    Topics: Case-Control Studies; Cholesterol, LDL; Coronary Disease; Female; Humans; Hypercholesterolemia; Male

1997
Effect of diet induced hypercholesterolemia and selenium supplementation on nitric oxide synthase activity.
    Archives of physiology and biochemistry, 1997, Volume: 105, Issue:6

    Topics: Animals; Antioxidants; Cholesterol; Cholesterol, Dietary; Citrulline; Enzyme Induction; Hypercholest

1997
Pressor hyperreactivity to mental and hand-grip stresses in patients with hypercholesterolemia.
    Journal of hypertension, 1999, Volume: 17, Issue:2

    Topics: Baroreflex; Blood Platelets; Blood Pressure; Calcium; Cyclic GMP; Heart Rate; Humans; Hypercholester

1999
A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA.
    Biochemical and biophysical research communications, 1999, Jun-07, Volume: 259, Issue:2

    Topics: Acyl Coenzyme A; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Endothelium, V

1999
Nitrite plasma levels in normolipemic and hypercholesterolemic arteriopathics after vasoactive and lipid-lowering treatment.
    Panminerva medica, 1999, Volume: 41, Issue:3

    Topics: Aged; Arteries; Female; Fibrinolytic Agents; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lip

1999
Nitrite plasma levels in normolipemic and hypercholesterolemic patients with peripheral occlusive arteriopathy.
    Panminerva medica, 1999, Volume: 41, Issue:4

    Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Hypercholesterolemia; Leg; Lipids; Male; Middle A

1999
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation;

2000
Paradoxical increase in nitric oxide synthase activity in hypercholesterolaemic rats with impaired renal function and decreased activity of nitric oxide.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:2

    Topics: Animals; Arginine; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Kidney; Male; NADPH Dehyd

2001
Is ceruloplasmin an important catalyst for S-nitrosothiol generation in hypercholesterolemia?
    Free radical biology & medicine, 2001, Feb-01, Volume: 30, Issue:3

    Topics: Apolipoproteins B; Ascorbic Acid; Catalysis; Ceruloplasmin; Cholesterol; Cholesterol Esters; Cholest

2001