nitrites has been researched along with Huntington Disease in 14 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QA) is an excitotoxin that induces Huntington's-like symptoms in animals and humans." | 1.43 | Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats. ( Kumar, P; Singh, S, 2016) |
| "Huntington's disease is an autosomal dominant, progressive, and fatal neurodegenerative disease characterized by motor and non-motor symptoms." | 1.40 | Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats. ( Deshmukh, R; Khan, A; Kumar, P; Lal Sharma, P, 2014) |
| "Huntington's disease is a progressive neurodegenerative disorder that gradually reduces memory, cognitive skills and normal movements of affected individuals." | 1.38 | Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity. ( Kalonia, H; Kumar, A; Kumar, P, 2012) |
| "Huntington disease is a neurodegenerative disease with complex pathophysiology." | 1.37 | Attenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats. ( Kalonia, H; Kumar, A; Kumar, P, 2011) |
| "Huntington's disease is characterized by abnormal body movements (chorea) and cognitive dysfunctions." | 1.35 | Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations. ( Kumar, A; Kumar, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, A | 8 |
| Chaudhary, T | 1 |
| Mishra, J | 2 |
| Kumar, P | 9 |
| Khan, A | 1 |
| Deshmukh, R | 1 |
| Lal Sharma, P | 1 |
| Kaur, M | 1 |
| Prakash, A | 1 |
| Kalia, AN | 1 |
| Singh, S | 1 |
| Kalonia, H | 5 |
| Túnez, I | 1 |
| Drucker-Colín, R | 1 |
| Jimena, I | 1 |
| Medina, FJ | 1 |
| Muñoz, Mdel C | 1 |
| Peña, J | 1 |
| Montilla, P | 1 |
| Milstien, S | 1 |
| Sakai, N | 1 |
| Brew, BJ | 1 |
| Krieger, C | 1 |
| Vickers, JH | 1 |
| Saito, K | 1 |
| Heyes, MP | 1 |
| Gerbeaux, J | 1 |
| Tournier, G | 1 |
| Labrune, B | 1 |
1 review available for nitrites and Huntington Disease
| Article | Year |
|---|---|
[Pediatrics in 1976].
Topics: Adolescent; alpha 1-Antitrypsin Deficiency; Body Weight; Carcinoma, Hepatocellular; Catheterization; | 1977 |
13 other studies available for nitrites and Huntington Disease
| Article | Year |
|---|---|
Minocycline modulates neuroprotective effect of hesperidin against quinolinic acid induced Huntington's disease like symptoms in rats: behavioral, biochemical, cellular and histological evidences.
Topics: Animals; Behavior, Animal; Brain; Caspase 3; Disease Models, Animal; Drug Synergism; Electron Transp | 2013 |
Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Brain; Catalase; Glutathione; Huntington Disease; Interleukin-1beta; Lipi | 2014 |
Neuroprotective potential of antioxidant potent fractions from Convolvulus pluricaulis Chois. in 3-nitropropionic acid challenged rats.
Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Convolvulus; Corpus Striatum; Glutathione; Hun | 2016 |
Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats.
Topics: Adenosine; Alkaloids; Animals; Antioxidants; Benzodioxoles; Brain; Catecholamines; Curcumin; Cytokin | 2016 |
Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations.
Topics: Administration, Oral; Animals; Behavior, Animal; Brain; Brain Chemistry; Cholinesterase Inhibitors; | 2009 |
Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Catalase; Corpus Striatum; Disease Models, | 2010 |
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carotenoids; Catalase; Coloring Agents; Electron Tran | 2009 |
Attenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats.
Topics: Analysis of Variance; Animals; Apoptosis; Body Weight; Calcium Channel Blockers; Catalase; Cytokines | 2011 |
Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Body Weight; Caspase 3; Corpus Striatum; Dinopro | 2011 |
Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity.
Topics: Amines; Animals; Body Weight; Brain; Catalase; Cyclohexanecarboxylic Acids; GABAergic Neurons; Gabap | 2012 |
Targeting neuro-inflammatory cytokines and oxidative stress by minocycline attenuates quinolinic-acid-induced Huntington's disease-like symptoms in rats.
Topics: Analysis of Variance; Animals; Body Weight; Catalase; Cytokines; Disease Models, Animal; Dose-Respon | 2012 |
Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease.
Topics: Animals; Catalase; Cell Count; Cell Death; Corpus Striatum; Disease Models, Animal; Glutathione; Hun | 2006 |
Cerebrospinal fluid nitrite/nitrate levels in neurologic diseases.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Biopterins; HIV Infections; Humans; Hunti | 1994 |