Page last updated: 2024-10-19

nitrites and Hemorrhage, Subarachnoid

nitrites has been researched along with Hemorrhage, Subarachnoid in 21 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)."7.70Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000)
" This study tested the hypothesis that enhancement of S-nitrosylated hemoglobin by ethyl nitrite inhalation improves outcome after experimental subarachnoid hemorrhage (SAH)."3.77Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. ( Auten, RL; Demchenko, IT; Piantadosi, CA; Reynolds, JD; Sheng, H; Stamler, JS; Warner, DS, 2011)
"Subacute sodium nitrite infusions prevented delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage."3.73Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. ( Dejam, A; Gladwin, MT; Grimes, G; Oldfield, EH; Pluta, RM, 2005)
"To test whether migraine and subarachnoid hemorrhage (SAH) are associated with increased sympathetic tone, we compared the neuropeptide Y-like (NPY-LI) and chromogranin A-like immunoreactivities (LI) of cerebrospinal fluid (CSF) from migraneurs and SAH patients with those from control subjects."3.70Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF. ( Donoso, MV; Huidobro-Toro, JP; Mellado, PA; Valenzuela, RF, 2000)
"Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)."3.70Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000)
"Delayed cerebral vasospasm after subarachnoid hemorrhage (SAH) may be evoked by the decreased availability of nitric oxide (NO)."1.34Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. ( Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M, 2007)
"The pathogenesis of cerebral vasospasm is likely to be multifactorial."1.32Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage. ( Böker, DK; Deinsberger, W; Woszczyk, A, 2003)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's2 (9.52)18.2507
2000's16 (76.19)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sheng, H1
Reynolds, JD1
Auten, RL1
Demchenko, IT1
Piantadosi, CA1
Stamler, JS1
Warner, DS1
Fathi, AR1
Pluta, RM3
Bakhtian, KD1
Qi, M1
Lonser, RR1
Shin, HK1
Lee, JH1
Kim, CD1
Kim, YK1
Hong, JY1
Hong, KW1
Woszczyk, A1
Deinsberger, W1
Böker, DK1
Rejdak, K1
Petzold, A1
Sharpe, MA1
Kay, AD1
Kerr, M1
Keir, G1
Thompson, EJ1
Giovannoni, G1
Dejam, A1
Grimes, G1
Gladwin, MT1
Oldfield, EH2
Lin, CL1
Hsu, YT1
Lin, TK1
Morrow, JD1
Hsu, JC1
Hsu, YH1
Hsieh, TC1
Tsay, PK1
Yen, HC1
Yatsushige, H1
Calvert, JW1
Cahill, J1
Zhang, JH1
Martens-Lobenhoffer, J1
Sulyok, E1
Czeiter, E1
Büki, A1
Kohl, J1
Firsching, R1
Tröger, U1
Bode-Böger, SM1
Jung, CS1
Harvey-White, J1
Espey, MG1
Zimmermann, M1
Seifert, V1
Suzuki, Y1
Osuka, K1
Noda, A1
Tanazawa, T1
Takayasu, M1
Shibuya, M1
Yoshida, J1
Suzuki, M1
Asahara, H1
Endo, S2
Inada, K1
Doi, M1
Kuroda, K1
Ogawa, A1
Valenzuela, RF1
Donoso, MV1
Mellado, PA1
Huidobro-Toro, JP1
Sehba, FA1
Schwartz, AY1
Chereshnev, I1
Bederson, JB1
Staub, F1
Graf, R1
Gabel, P1
Köchling, M1
Klug, N1
Heiss, WD1
Takenaka, KV1
Sakai, N1
Murase, S1
Kuroda, T1
Okumura, A1
Sawada, M1
Sadamitsu, D1
Kuroda, Y1
Nagamitsu, T1
Tsuruta, R1
Inoue, T1
Ueda, T1
Nakashima, K1
Ito, H1
Maekawa, T1
Khaldi, A2
Zauner, A2
Reinert, M2
Woodward, JJ1
Bullock, MR1
Sakowitz, OW1
Wolfrum, S1
Sarrafzadeh, AS1
Stover, JF1
Dreier, JP1
Dendorfer, A1
Benndorf, G1
Lanksch, WR1
Unterberg, AW1
Seiler, R1
Bullock, R1
Sakurai, Y1
Sonobe, M1
Suzuki, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2, Multi-Center, Open-label, Randomized, Parallel-Dose Study to Determine the Safety and Efficacy of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension (PAH)[NCT01725256]Phase 229 participants (Actual)Interventional2012-11-30Terminated (stopped due to Terminated early dt to acquisition of Sponsor and change in corporate priorities)
Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453]150 participants (Actual)Observational2021-08-18Active, not recruiting
Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage[NCT05686265]32 participants (Anticipated)Observational2023-05-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

21 other studies available for nitrites and Hemorrhage, Subarachnoid

ArticleYear
Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage.
    Stroke, 2011, Volume: 42, Issue:2

    Topics: Adjuvants, Pharmaceutic; Administration, Inhalation; Animals; Drug Synergism; Hemoglobins; Male; Mic

2011
Reversal of cerebral vasospasm via intravenous sodium nitrite after subarachnoid hemorrhage in primates.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infusions, Intravenous; Macaca fascicularis;

2011
Prevention of impairment of cerebral blood flow autoregulation during acute stage of subarachnoid hemorrhage by gene transfer of Cu/Zn SOD-1 to cerebral vessels.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:1

    Topics: Adenoviridae; Animals; Arteries; Blood Vessels; Cerebrovascular Circulation; Gene Expression; Gene T

2003
Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage.
    Acta neurochirurgica, 2003, Volume: 145, Issue:4

    Topics: Adult; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Cisterna Magna; Female; Humans; Intra

2003
Cerebrospinal fluid nitrite/nitrate correlated with oxyhemoglobin and outcome in patients with subarachnoid hemorrhage.
    Journal of the neurological sciences, 2004, Apr-15, Volume: 219, Issue:1-2

    Topics: Adult; Aged; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Oxyhemoglobins; Pred

2004
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.
    JAMA, 2005, Mar-23, Volume: 293, Issue:12

    Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infarction, Middle Cerebral Artery; Infusions

2005
Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans.
    Free radical biology & medicine, 2006, Apr-15, Volume: 40, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm; Antioxidants; Biomarkers; F2-Isoprostanes; Female; Humans;

2006
Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
    Journal of neurotrauma, 2006, Volume: 23, Issue:12

    Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Male; Nitrates

2006
Determination of cerebrospinal fluid concentrations of arginine and dimethylarginines in patients with subarachnoid haemorrhage.
    Journal of neuroscience methods, 2007, Aug-15, Volume: 164, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Brain; Cerebrospinal Fluid; Female; Gas Chromatography-Mas

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Nitric oxide metabolites in the cisternal cerebral spinal fluid of patients with subarachnoid hemorrhage.
    Neurosurgery, 1997, Volume: 41, Issue:4

    Topics: Adult; Aged; Aneurysm, Ruptured; Cisterna Magna; Enzyme Induction; Female; Hemifacial Spasm; Humans;

1997
Increased levels of nitrite/nitrate in the cerebrospinal fluid of patients with subarachnoid hemorrhage.
    Neurosurgical review, 1999, Volume: 22, Issue:2-3

    Topics: Humans; Nitrates; Nitric Oxide; Nitrites; Reference Values; Subarachnoid Hemorrhage; Vasospasm, Intr

1999
Migraine, but not subarachnoid hemorrhage, is associated with differentially increased NPY-like immunoreactivity in the CSF.
    Journal of the neurological sciences, 2000, Feb-15, Volume: 173, Issue:2

    Topics: Adult; Biomarkers; Cerebrospinal Fluid Proteins; Chromogranin A; Chromogranins; Female; Humans; Male

2000
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:3

    Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr

2000
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:3

    Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr

2000
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:3

    Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr

2000
Acute decrease in cerebral nitric oxide levels after subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:3

    Topics: Animals; Brain; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitr

2000
Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhage.
    Neurosurgery, 2000, Volume: 47, Issue:5

    Topics: Acute Disease; Adult; Aged; Aneurysm, Ruptured; Biomarkers; Brain; Catecholamines; Cerebrospinal Flu

2000
Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage.
    Neurological research, 2000, Volume: 22, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Animals; Aorta, Thoracic; Cells, Cultured; Female; Gene Expression R

2000
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites in postoperative patients with subarachnoid hemorrhage.
    Critical care medicine, 2001, Volume: 29, Issue:1

    Topics: Adult; Analysis of Variance; Case-Control Studies; Female; Humans; Intracranial Aneurysm; Male; Midd

2001
Measurement of nitric oxide and brain tissue oxygen tension in patients after severe subarachnoid hemorrhage.
    Neurosurgery, 2001, Volume: 49, Issue:1

    Topics: Adult; Aged; Brain; Female; Humans; Male; Microdialysis; Middle Aged; Nitrates; Nitric Oxide; Nitrit

2001
Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:9

    Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Fe

2001
Microdialysis nitric oxide levels and brain tissue oxygen tension in patients with subarachnoid hemorrhage.
    Acta neurochirurgica. Supplement, 2001, Volume: 77

    Topics: Brain; Energy Metabolism; Humans; Microdialysis; Nitrates; Nitric Oxide; Nitrites; Oxygen; Partial P

2001
[Cerebral vasospasm caused by subarachnoid hemorrhage and its management, with special reference to the vasospastic effects of oxyhemoglobin].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: 36, Issue:3

    Topics: Animals; Cats; Humans; Ischemic Attack, Transient; Nitrites; Oxyhemoglobins; Subarachnoid Hemorrhage

1978