nitrites has been researched along with Heart Disease, Ischemic in 49 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Excerpt | Relevance | Reference |
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"Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs." | 7.81 | Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015) |
"Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs." | 3.81 | Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015) |
"Previous studies indicate that adenosine supplementation or nitric oxide synthase (NOS) inhibition during reperfusion exert protective effects against myocardial ischemia-reperfusion (I/R) injury." | 3.74 | Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury. ( Bouhaddi, M; Davani, S; Kantelip, JP; Reyssie, H; Rochette, L; Royer, B; Vergely, C, 2007) |
") is thought to protect against the damaging effects of myocardial ischemia-reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species." | 3.72 | Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. ( Ahluwalia, A; Benjamin, N; Bond, R; McLean, P; Uppal, R; Webb, A, 2004) |
"There were studied 22 patients with ischemic heart disease, who performed two effort tests at 24-hour interval." | 2.71 | Ischemic preconditioning by repeated exercise tests involves nitric oxide up-regulation. ( Bódizs, G; Ilea, M; Ober, MC; Zdrenghea, D, 2003) |
"Asymptomatic myocardial ischemia is commonly observed in patients with coronary artery disease." | 2.40 | Treatment of asymptomatic myocardial ischemia. ( Hilleman, DE; Mohiuddin, SM; Mooss, AN, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 14 (28.57) | 18.2507 |
2000's | 26 (53.06) | 29.6817 |
2010's | 9 (18.37) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Liu, Y | 1 |
Buerk, DG | 1 |
Barbee, KA | 1 |
Jaron, D | 1 |
Totzeck, M | 2 |
Korste, S | 1 |
Miinalainen, I | 1 |
Hendgen-Cotta, UB | 2 |
Rassaf, T | 2 |
Chouchani, ET | 1 |
James, AM | 1 |
Methner, C | 1 |
Pell, VR | 1 |
Prime, TA | 1 |
Erickson, BK | 1 |
Forkink, M | 1 |
Lau, GY | 1 |
Bright, TP | 1 |
Menger, KE | 1 |
Fearnley, IM | 1 |
Krieg, T | 1 |
Murphy, MP | 1 |
Wang, Y | 1 |
Song, X | 1 |
Yue, X | 1 |
Su, H | 1 |
Gu, Y | 1 |
Bowman, L | 1 |
Ding, M | 1 |
Zou, B | 1 |
Zhao, J | 1 |
Lin, X | 1 |
Shiva, S | 1 |
Heusch, G | 1 |
Kelm, M | 1 |
Corti, P | 1 |
Gladwin, MT | 1 |
Kovács, M | 1 |
Kiss, A | 1 |
Gönczi, M | 1 |
Miskolczi, G | 1 |
Seprényi, G | 1 |
Kaszaki, J | 1 |
Kohr, MJ | 1 |
Murphy, E | 1 |
Végh, Á | 1 |
McNulty, PH | 1 |
Scott, S | 1 |
Kehoe, V | 1 |
Kozak, M | 1 |
Sinoway, LI | 1 |
Li, J | 1 |
Kevil, CG | 1 |
Patel, RP | 1 |
Akinmoladun, AC | 1 |
Obuotor, EM | 1 |
Barthwal, MK | 1 |
Dikshit, M | 1 |
Farombi, EO | 1 |
Wang, E | 1 |
Feng, Y | 1 |
Zhang, M | 1 |
Zou, L | 1 |
Li, Y | 2 |
Buys, ES | 1 |
Huang, P | 1 |
Brouckaert, P | 1 |
Chao, W | 1 |
Maczewski, M | 1 |
Beresewicz, A | 1 |
Sharma, M | 1 |
Ganguly, NK | 1 |
Chaturvedi, G | 1 |
Thingnam, SK | 1 |
Majumdar, S | 1 |
Suri, RK | 1 |
Elfatih, A | 1 |
Anderson, NR | 1 |
Mansoor, S | 1 |
Ahmed, S | 1 |
Horton, R | 1 |
Holland, M | 1 |
Gama, R | 1 |
Vardugina, NG | 1 |
Volkova, EG | 1 |
Orlova, NS | 1 |
Kato, Y | 1 |
Kijima, Y | 1 |
Kitakaze, M | 3 |
Minamino, T | 3 |
Matsu-Ura, Y | 1 |
Hashimura, K | 1 |
Yasuda, T | 1 |
Ueda, T | 1 |
Mori, I | 1 |
Hori, M | 3 |
Webb, A | 1 |
Bond, R | 1 |
McLean, P | 1 |
Uppal, R | 1 |
Benjamin, N | 1 |
Ahluwalia, A | 1 |
Zdrenghea, D | 1 |
Bódizs, G | 1 |
Ober, MC | 1 |
Ilea, M | 1 |
Iida, K | 1 |
Li, H | 1 |
Cui, H | 1 |
Liu, X | 1 |
Zweier, JL | 4 |
Ding, HL | 1 |
Zhu, HF | 1 |
Dong, JW | 1 |
Zhu, WZ | 1 |
Yang, WW | 1 |
Yang, HT | 1 |
Zhou, ZN | 1 |
Shi, Y | 1 |
Hutchins, W | 1 |
Ogawa, H | 1 |
Chang, CC | 1 |
Pritchard, KA | 3 |
Zhang, C | 1 |
Khampang, P | 1 |
Lazar, J | 1 |
Jacob, HJ | 1 |
Rafiee, P | 1 |
Baker, JE | 3 |
Kuralay, F | 1 |
Altekin, E | 1 |
Yazlar, AS | 1 |
Onvural, B | 1 |
Goldeli, O | 1 |
Andreotti, F | 1 |
Coluzzi, G | 1 |
Lavorgna, A | 1 |
Marzo, F | 1 |
Di Stasio, E | 1 |
Carrozza, C | 1 |
Zuppi, C | 1 |
Crea, F | 1 |
Davani, S | 1 |
Vergely, C | 1 |
Royer, B | 1 |
Bouhaddi, M | 1 |
Reyssie, H | 1 |
Rochette, L | 2 |
Kantelip, JP | 1 |
Kharlamova, NV | 1 |
Chasha, TV | 1 |
Shilova, NA | 1 |
Kuz'menko, GN | 1 |
Klimova, OI | 1 |
van der Vliet, HJ | 1 |
Kuenen, BC | 1 |
Hu, A | 1 |
Jiao, X | 1 |
Gao, E | 1 |
Sharifi-Azad, S | 1 |
Grunwald, Z | 1 |
Ma, XL | 2 |
Sun, JZ | 1 |
Meyer, DJ | 1 |
Wang, P | 1 |
Samouilov, A | 3 |
Kuppusamy, P | 3 |
Node, K | 1 |
Kosaka, H | 1 |
Komamura, K | 1 |
Tada, M | 1 |
Inoue, M | 1 |
Kamada, T | 1 |
van Jaarsveld, H | 1 |
Schulenburg, DH | 1 |
Sato, H | 1 |
Asanuma, H | 1 |
Funaya, H | 1 |
Koretsune, Y | 1 |
Akiyama, K | 1 |
Kimura, A | 1 |
Suzuki, H | 1 |
Takeyama, Y | 1 |
Gluckman, TL | 1 |
Terhakopian, A | 1 |
Katagiri, T | 1 |
Suh, KY | 1 |
Roseto, J | 1 |
Bing, RJ | 1 |
Holman, P | 2 |
Kalyanaraman, B | 2 |
Kouretas, PC | 1 |
Kim, YD | 1 |
Cahill, PA | 1 |
Myers, AK | 1 |
To, LN | 1 |
Wang, YN | 1 |
Sitzmann, JV | 1 |
Hannan, RL | 1 |
Griffith, OW | 1 |
Parikh, V | 1 |
Singh, M | 1 |
Mooss, AN | 1 |
Hilleman, DE | 1 |
Mohiuddin, SM | 1 |
Gao, F | 1 |
Liu, GL | 1 |
Lopez, BL | 1 |
Christopher, TA | 1 |
Fukuto, JM | 1 |
Wink, DA | 1 |
Feelisch, M | 1 |
Shen, JG | 1 |
Quo, XS | 1 |
Jiang, B | 1 |
Li, M | 1 |
Xin, W | 1 |
Zhao, BL | 1 |
Giroux, M | 1 |
Ruidavets, JB | 1 |
Ferrières, J | 1 |
Zhai, P | 1 |
Eurell, TE | 1 |
Cooke, PS | 1 |
Lubahn, DB | 1 |
Gross, DR | 1 |
Clausen, P | 1 |
Jensen, JS | 1 |
Jensent, G | 1 |
Feldt-Rasmussen, B | 1 |
Lecour, S | 1 |
Maupoil, V | 1 |
Zeller, M | 1 |
Laubriet, A | 1 |
Briot, T | 1 |
Liu, P | 1 |
Xu, B | 1 |
Forman, LJ | 1 |
Carsia, R | 1 |
Hock, CE | 1 |
Stevens, RM | 1 |
Jahania, MS | 1 |
Stivers, JE | 1 |
Mentzer, RM | 1 |
Lasley, RD | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
The Impact of Dietary Cocoa Flavanols on Cardio-pulmonary Exercise Capacity in Human.[NCT01259739] | 13 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress[NCT00250185] | Phase 1 | 135 participants | Interventional | 2005-11-01 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for nitrites and Heart Disease, Ischemic
Article | Year |
---|---|
[Vasodilator: nitrate and nitrite].
Topics: Biomarkers; Chromatography, Gas; Dosage Forms; Drug Monitoring; Drug Therapy, Combination; Drug Tole | 2004 |
Non-enzymatic nitric oxide synthesis in biological systems.
Topics: Animals; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heart; Hemeproteins; Hydrogen-Ion | 1999 |
Treatment of asymptomatic myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Myocardial Ischemia | 1999 |
2 trials available for nitrites and Heart Disease, Ischemic
Article | Year |
---|---|
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning.
Topics: Animals; Forearm; Hindlimb; Humans; Hyperemia; Ischemic Preconditioning; Ischemic Preconditioning, M | 2014 |
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning.
Topics: Animals; Forearm; Hindlimb; Humans; Hyperemia; Ischemic Preconditioning; Ischemic Preconditioning, M | 2014 |
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning.
Topics: Animals; Forearm; Hindlimb; Humans; Hyperemia; Ischemic Preconditioning; Ischemic Preconditioning, M | 2014 |
Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning.
Topics: Animals; Forearm; Hindlimb; Humans; Hyperemia; Ischemic Preconditioning; Ischemic Preconditioning, M | 2014 |
Ischemic preconditioning by repeated exercise tests involves nitric oxide up-regulation.
Topics: Adult; Aged; Blood Pressure; Exercise Test; Female; Heart Rate; Humans; Ischemic Preconditioning, My | 2003 |
44 other studies available for nitrites and Heart Disease, Ischemic
Article | Year |
---|---|
Nitric oxide release by deoxymyoglobin nitrite reduction during cardiac ischemia: A mathematical model.
Topics: Animals; Arterioles; Blood Flow Velocity; Cell Hypoxia; Computer Simulation; Coronary Circulation; H | 2017 |
S-nitrosation of calpains is associated with cardioprotection in myocardial I/R injury.
Topics: Animals; Calpain; Cell Line; Male; Mice, Inbred C57BL; Mitochondria; Myocardial Infarction; Myocardi | 2017 |
Identification and quantification of protein
Topics: Affinity Labels; Animals; Cardiotonic Agents; Cell Membrane Permeability; Cysteine; Disease Models, | 2017 |
Protection by nitrite against the ischemic effects induced by acute myocardial infarction in mice.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Disease Models, Animal; Male; Mice; Mice, Inbred | 2017 |
Is nitrite the circulating endocrine effector of remote ischemic preconditioning?
Topics: Animals; Humans; Ischemic Preconditioning; Male; Myocardial Ischemia; Nitric Oxide Synthase Type III | 2014 |
Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved?
Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, | 2015 |
Nitrite consumption in ischemic rat heart catalyzed by distinct blood-borne and tissue factors.
Topics: Allopurinol; Animals; Catalysis; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Glucose; G | 2008 |
Preserving vessel function during ischemic disease: new possibilities of inorganic nitrite therapy.
Topics: Acute Disease; Animals; Chronic Disease; Coronary Vessels; Humans; Myocardial Ischemia; Nitric Oxide | 2008 |
Ramipril-like activity of Spondias mombin linn against no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart.
Topics: Anacardiaceae; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Catalase; C | 2010 |
Toll-like receptor 4 signaling confers cardiac protection against ischemic injury via inducible nitric oxide synthase- and soluble guanylate cyclase-dependent mechanisms.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Echocardiography; Electrocardiography; Guanylate Cyc | 2011 |
Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radicals; G | 2003 |
Release of pro-inflammatory mediators during myocardial ischemia/reperfusion in coronary artery bypass graft surgery.
Topics: Aged; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Biomarkers; CD4 Antigens; Cell Adhesion | 2003 |
An investigation of nitric oxide metabolites during symptomatic myocardial ischaemia in relation to exercise tolerance test.
Topics: Adult; Aged; Case-Control Studies; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Isch | 2003 |
[Dependence of nitric oxide level in blood on the degree of damage in coronary vessels in women younger than 55 years with ischemic heart disease].
Topics: Adult; Coronary Angiography; Coronary Vessels; Female; Humans; Middle Aged; Myocardial Ischemia; Nit | 2004 |
Roles of systemic nitric oxide metabolites for human coronary circulation.
Topics: Acetylcholine; Aorta; Cholesterol; Coronary Angiography; Coronary Circulation; Coronary Vasospasm; C | 2004 |
Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage.
Topics: Animals; Cardiotonic Agents; Humans; Hydrogen-Ion Concentration; Male; Myocardial Ischemia; Myocardi | 2004 |
Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation.
Topics: Anions; Benzaldehydes; Binding Sites; Biotransformation; Catechols; Electrochemistry; Electrodes; El | 2005 |
Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Guanidines; Hypoxia; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion | 2005 |
Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: role of nitric oxide synthase and Hsp90.
Topics: Animals; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Myocardial Ischemia; Nerve Tissue Proteins; N | 2005 |
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidine.
Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Huma | 2006 |
Relation between nitric oxide metabolites and haemoglobin concentrations in patients with ischaemic heart disease.
Topics: Aged; Biological Availability; Female; Hematopoiesis; Hemoglobins; Humans; Male; Middle Aged; Multiv | 2007 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inh | 2007 |
[The levels of nitrites and medium molecular-weight molecules in the blood of neonatal infants with posthypoxic cardiopathy].
Topics: Cardiomyopathies; Female; Fetal Hypoxia; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; Myo | 2007 |
[Myocardial ischaemia as a result of treatment with capecitabine].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Myocardial Ische | 2007 |
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Amidines; Animals; Apoptosis; Benzylam | 2008 |
Enzymatic/non-enzymatic formation of nitric oxide.
Topics: Animals; Electron Transport Complex IV; Mitochondria, Heart; Myocardial Ischemia; Myocardium; Nitric | 1995 |
Enzyme-independent formation of nitric oxide in biological tissues.
Topics: Animals; Electron Spin Resonance Spectroscopy; Female; Heme; Hydrogen-Ion Concentration; In Vitro Te | 1995 |
Plasma nitric oxide end products are increased in the ischemic canine heart.
Topics: Animals; Arginine; Coronary Circulation; Coronary Vessels; Dogs; Hemodynamics; Myocardial Ischemia; | 1995 |
Dietary iron alters liver, erythrocyte and plasma antioxidant and nitrite levels, and also sensitizes the heart to ischemia/reperfusion.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Erythrocytes; Female; Glutathione Peroxidase; Heart; | 1997 |
Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation.
Topics: Aged; Atrial Fibrillation; beta-Thromboglobulin; Blood Platelets; Blood Proteins; Cerebrovascular Di | 1997 |
Production of oxidative products of nitric oxide in infarcted human heart.
Topics: Aged; Aged, 80 and over; Arteries; Coronary Angiography; Coronary Vessels; Diastole; Female; Follow- | 1998 |
Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems.
Topics: Animals; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Kinetics; Luminescent Measure | 1998 |
Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Topics: Aging; Animals; Cyclic GMP; Gene Expression Regulation, Developmental; Gene Expression Regulation, E | 1998 |
Nonanticoagulant heparin prevents coronary endothelial dysfunction after brief ischemia-reperfusion injury in the dog.
Topics: Animals; Anticoagulants; Blood Coagulation; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascula | 1999 |
Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production.
Topics: Adaptation, Physiological; Animals; Chronic Disease; Cyclic GMP; Hypoxia; Myocardial Ischemia; Myoca | 1999 |
Possible role of cardiac mast cell degranulation and preservation of nitric oxide release in isolated rat heart subjected to ischaemic preconditioning.
Topics: Animals; Cell Degranulation; Creatine Kinase; Female; In Vitro Techniques; Ischemic Preconditioning, | 1999 |
Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Glutathione; Hemodynamics; Male; Myocardial Ischemia; | 1999 |
Chinonin, a novel drug against cardiomyocyte apoptosis induced by hypoxia and reoxygenation.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; Biomarkers; Cell Hypoxia; Cells, Cultured; DNA Fra | 2000 |
Atmospheric NO, temperature and ischaemic heart disease. Study in Toulouse and its conurbation.
Topics: Air; Ammonia; France; Humans; Humidity; Myocardial Infarction; Myocardial Ischemia; Nitric Oxide; Ni | 2000 |
Myocardial ischemia-reperfusion injury in estrogen receptor-alpha knockout and wild-type mice.
Topics: Animals; Calcium; Coronary Circulation; Edema, Cardiac; Estrogen Receptor alpha; Heart Rate; In Vitr | 2000 |
Plasma concentrations of endothelial vasoactive substances in clinically healthy subjects. associations with urinary albumin excretion and ambulatory blood pressure.
Topics: Aged; Albuminuria; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Endothelin-1; Endothelium, | 2000 |
Levels of nitric oxide in the heart after experimental myocardial ischemia.
Topics: Animals; Chelating Agents; Coronary Vessels; Electron Spin Resonance Spectroscopy; Guanidines; Hemog | 2001 |
L-NAME enhances microcirculatory congestion and cardiomyocyte apoptosis during myocardial ischemia-reperfusion in rats.
Topics: Animals; Apoptosis; Blood Pressure; Cytochrome c Group; DNA Fragmentation; Enzyme-Linked Immunosorbe | 2002 |
Effects of in vivo myocardial ischemia and reperfusion on interstitial nitric oxide metabolites.
Topics: Animals; Extracellular Space; Ischemic Preconditioning, Myocardial; Microdialysis; Myocardial Ischem | 2002 |