nitrites has been researched along with Gaucher Disease in 1 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Enzyme dosage ranged from 120 to 480 U/kg of body weight/month." | 2.68 | Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease. ( Aerts, JM; Barton, NW; Brady, RO; Dambrosia, JM; DeGraba, T; Heyes, MP; Oliver, K; Parker, CC; Patterson, MC; Schiffmann, R; Tedeschi, G; Zirzow, GC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schiffmann, R | 1 |
| Heyes, MP | 1 |
| Aerts, JM | 1 |
| Dambrosia, JM | 1 |
| Patterson, MC | 1 |
| DeGraba, T | 1 |
| Parker, CC | 1 |
| Zirzow, GC | 1 |
| Oliver, K | 1 |
| Tedeschi, G | 1 |
| Brady, RO | 1 |
| Barton, NW | 1 |
1 trial available for nitrites and Gaucher Disease
| Article | Year |
|---|---|
Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease.
Topics: Antibodies; Biomarkers; Child; Child, Preschool; Electroencephalography; Evoked Potentials, Auditory | 1997 |