Page last updated: 2024-10-19

nitrites and Encephalopathy, Hepatic

nitrites has been researched along with Encephalopathy, Hepatic in 10 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
" However, acute and chronic administration of L-NAME did not change HE scores in cirrhotic rats."5.46Nitric oxide mediates effects of acute, not chronic, naltrexone on LPS-induced hepatic encephalopathy in cirrhotic rats. ( Dehpour, AR; Gharedaghi, MH; Ghiassy, B; Javadi-Paydar, M; Norouzi-Javidan, A; Rahimi, N, 2017)
"Hepatic encephalopathy is a complex neuropsychiatric syndrome seen secondary to acute liver failure, chronic parenchymal liver disease, or portal-systemic anastomosis."5.31Detrimental effects of nitric oxide inhibition on hepatic encephalopathy in rats with thioacetamide-induced fulminant hepatic failure. ( Chan, CC; Chang, FY; Chen, CT; Chu, CJ; Hou, MC; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS; Wu, SL, 2001)
" The aim of this study was to assess the effects of simvastatin on rats with TAA-induced acute liver damage and hepatic encephalopathy."3.74Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy. ( Chan, CY; Chang, FY; Chen, YC; Chu, CJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS, 2008)
"Minimal hepatic encephalopathy (MHE) is common in cirrhosis but its pathophysiologic basis remains undefined."2.73Role of ammonia and inflammation in minimal hepatic encephalopathy. ( Jalan, R; Olde Damink, SW; Shawcross, DL; Wright, G, 2007)
" However, acute and chronic administration of L-NAME did not change HE scores in cirrhotic rats."1.46Nitric oxide mediates effects of acute, not chronic, naltrexone on LPS-induced hepatic encephalopathy in cirrhotic rats. ( Dehpour, AR; Gharedaghi, MH; Ghiassy, B; Javadi-Paydar, M; Norouzi-Javidan, A; Rahimi, N, 2017)
"The pathogenetic mechanisms of hepatic encephalopathy (HE) are not fully understood."1.32Lack of detrimental effects of nitric oxide inhibition in bile duct-ligated rats with hepatic encephalopathy. ( Chan, CC; Chan, CY; Chang, FY; Chen, YC; Chu, CJ; Huang, HC; Huang, SW; Lee, FY; Lee, SD; Lu, RH; Wang, TF, 2004)
"Hepatic encephalopathy is a complex neuropsychiatric syndrome seen secondary to acute liver failure, chronic parenchymal liver disease, or portal-systemic anastomosis."1.31Detrimental effects of nitric oxide inhibition on hepatic encephalopathy in rats with thioacetamide-induced fulminant hepatic failure. ( Chan, CC; Chang, FY; Chen, CT; Chu, CJ; Hou, MC; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS; Wu, SL, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghiassy, B1
Rahimi, N1
Javadi-Paydar, M1
Gharedaghi, MH1
Norouzi-Javidan, A1
Dehpour, AR1
Jiang, W1
Desjardins, P1
Butterworth, RF1
Chan, CY2
Huang, SW1
Wang, TF1
Lu, RH1
Lee, FY3
Chang, FY3
Chu, CJ3
Chen, YC2
Chan, CC2
Huang, HC3
Lee, SD3
Shawcross, DL1
Wright, G1
Olde Damink, SW1
Jalan, R1
Wang, SS2
Lin, HC2
Wendon, J1
Harrison, PM1
Heaton, N1
Williams, R1
Benjamin, N1
Vallance, P1
Genesca, J1
Gonzalez, A1
Segura, R1
Catalan, R1
Marti, R1
Varela, E1
Cadelina, G1
Martinez, M1
Lopez-Talavera, JC1
Esteban, R1
Groszmann, RJ1
Guardia, J1
Akahori, M1
Yamada, S1
Takeyama, N1
Tanaka, T1
Hou, MC1
Wu, SL1
Chen, CT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Therapeutic Effect of Rifaximin on Covert Hepatic Encephalopathy With Underlying Small Intestinal Bacterial Overgrowth and Gastrointestinal Dysmotility in Liver Cirrhosis Patients[NCT04244877]Phase 30 participants (Actual)Interventional2021-09-15Withdrawn (stopped due to Study was unable to recruit participants..)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nitrites and Encephalopathy, Hepatic

ArticleYear
Role of ammonia and inflammation in minimal hepatic encephalopathy.
    Metabolic brain disease, 2007, Volume: 22, Issue:1

    Topics: Adult; Aged; Amino Acids; Ammonia; Biomarkers; C-Reactive Protein; Female; Hepatic Encephalopathy; H

2007

Other Studies

9 other studies available for nitrites and Encephalopathy, Hepatic

ArticleYear
Nitric oxide mediates effects of acute, not chronic, naltrexone on LPS-induced hepatic encephalopathy in cirrhotic rats.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:1

    Topics: Animals; Drug Interactions; Hepatic Encephalopathy; Lipopolysaccharides; Liver; Liver Cirrhosis; Mal

2017
Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats.
    Neurochemistry international, 2009, Volume: 55, Issue:7

    Topics: Ammonia; Animals; Blotting, Western; Brain; Brain Chemistry; Disease Progression; Heme Oxygenase-1;

2009
Lack of detrimental effects of nitric oxide inhibition in bile duct-ligated rats with hepatic encephalopathy.
    European journal of clinical investigation, 2004, Volume: 34, Issue:2

    Topics: Animals; Blood Pressure; Heart Rate; Hepatic Encephalopathy; Male; Motor Activity; NG-Nitroarginine

2004
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:7 Pt 2

    Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Anim

2008
Serum nitrates as markers of postoperative morbidity.
    Lancet (London, England), 1994, Aug-06, Volume: 344, Issue:8919

    Topics: Biomarkers; Hepatic Encephalopathy; Humans; Interleukin-6; Morbidity; Nitrates; Nitrites; Nitrogen O

1994
Plasma nitrite as a marker of nitric oxide production.
    Lancet (London, England), 1994, Oct-01, Volume: 344, Issue:8927

    Topics: Hepatic Encephalopathy; Humans; Nitric Oxide; Nitrites

1994
Interleukin-6, nitric oxide, and the clinical and hemodynamic alterations of patients with liver cirrhosis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:1

    Topics: Aged; Aldosterone; Ascites; Blood Pressure; Endotoxins; Female; Hepatic Encephalopathy; Humans; Inte

1999
Nitric oxide ameliorates actinomycin D/endotoxin-induced apoptotic liver failure in mice.
    The Journal of surgical research, 1999, Volume: 85, Issue:2

    Topics: Aminoquinolines; Animals; Apoptosis; Dactinomycin; Dibutyryl Cyclic GMP; DNA Fragmentation; Hepatic

1999
Detrimental effects of nitric oxide inhibition on hepatic encephalopathy in rats with thioacetamide-induced fulminant hepatic failure.
    European journal of clinical investigation, 2001, Volume: 31, Issue:2

    Topics: Animals; Endotoxins; Hepatic Encephalopathy; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric O

2001