Page last updated: 2024-10-19

nitrites and Down Syndrome

nitrites has been researched along with Down Syndrome in 5 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research Excerpts

ExcerptRelevanceReference
" Thus, we aimed to assess a set of urinary oxidative/nitrosative stress biomarkers in children with DS, with and without hypothyroidism, which comprise: 8-hydroxy-2'-deoxyguanosine (8-OHdG), isoprostane 15-F(2t)-IsoP, thiobarbituric acid-reacting substances (TBARS), advanced glycation end products (AGEs), dityrosine (diTyr), hydrogen peroxide (H(2)O(2)) and nitrite/nitrate (NOx)."3.77Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome. ( Campos, C; Casado, A; Guzmán, R; López-Fernández, E, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cua, CL1
Rogers, LK1
Chicoine, LG1
Augustine, M1
Jin, Y1
Nash, PL1
Nelin, LD1
Campos, C1
Guzmán, R1
López-Fernández, E1
Casado, A1
Colas, D1
London, J1
Gharib, A1
Cespuglio, R1
Sarda, N1
Mirochnitchenko, O1
Inouye, M1
Hall, AH1
Linden, CH1
Kulig, KW1
Rumack, BH1

Other Studies

5 other studies available for nitrites and Down Syndrome

ArticleYear
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
    European journal of pediatrics, 2011, Volume: 170, Issue:7

    Topics: Arginine; Biomarkers; Down Syndrome; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates

2011
Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome.
    Life sciences, 2011, Oct-24, Volume: 89, Issue:17-18

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Biomarkers; Child; Child, Preschool; Deoxyguanosine; Dinopr

2011
Sleep-wake architecture in mouse models for Down syndrome.
    Neurobiology of disease, 2004, Volume: 16, Issue:2

    Topics: Animals; Brain Stem; Cerebral Cortex; Disease Models, Animal; Down Syndrome; Mice; Mice, Transgenic;

2004
Effect of overexpression of human Cu,Zn superoxide dismutase in transgenic mice on macrophage functions.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Feb-15, Volume: 156, Issue:4

    Topics: Animals; Base Sequence; Blood Bactericidal Activity; Cell Nucleus; DNA Primers; Down Syndrome; Human

1996
Cyanide poisoning from laetrile ingestion: role of nitrite therapy.
    Pediatrics, 1986, Volume: 78, Issue:2

    Topics: Acute Disease; Amygdalin; Antidotes; Child, Preschool; Cyanides; Down Syndrome; Humans; Male; Nitrit

1986