nitrites has been researched along with Down Syndrome in 5 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Excerpt | Relevance | Reference |
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" Thus, we aimed to assess a set of urinary oxidative/nitrosative stress biomarkers in children with DS, with and without hypothyroidism, which comprise: 8-hydroxy-2'-deoxyguanosine (8-OHdG), isoprostane 15-F(2t)-IsoP, thiobarbituric acid-reacting substances (TBARS), advanced glycation end products (AGEs), dityrosine (diTyr), hydrogen peroxide (H(2)O(2)) and nitrite/nitrate (NOx)." | 3.77 | Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome. ( Campos, C; Casado, A; Guzmán, R; López-Fernández, E, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cua, CL | 1 |
Rogers, LK | 1 |
Chicoine, LG | 1 |
Augustine, M | 1 |
Jin, Y | 1 |
Nash, PL | 1 |
Nelin, LD | 1 |
Campos, C | 1 |
Guzmán, R | 1 |
López-Fernández, E | 1 |
Casado, A | 1 |
Colas, D | 1 |
London, J | 1 |
Gharib, A | 1 |
Cespuglio, R | 1 |
Sarda, N | 1 |
Mirochnitchenko, O | 1 |
Inouye, M | 1 |
Hall, AH | 1 |
Linden, CH | 1 |
Kulig, KW | 1 |
Rumack, BH | 1 |
5 other studies available for nitrites and Down Syndrome
Article | Year |
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Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
Topics: Arginine; Biomarkers; Down Syndrome; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates | 2011 |
Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Biomarkers; Child; Child, Preschool; Deoxyguanosine; Dinopr | 2011 |
Sleep-wake architecture in mouse models for Down syndrome.
Topics: Animals; Brain Stem; Cerebral Cortex; Disease Models, Animal; Down Syndrome; Mice; Mice, Transgenic; | 2004 |
Effect of overexpression of human Cu,Zn superoxide dismutase in transgenic mice on macrophage functions.
Topics: Animals; Base Sequence; Blood Bactericidal Activity; Cell Nucleus; DNA Primers; Down Syndrome; Human | 1996 |
Cyanide poisoning from laetrile ingestion: role of nitrite therapy.
Topics: Acute Disease; Amygdalin; Antidotes; Child, Preschool; Cyanides; Down Syndrome; Humans; Male; Nitrit | 1986 |