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nitrites and Diabetic Glomerulosclerosis

nitrites has been researched along with Diabetic Glomerulosclerosis in 22 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"Treatment with fenofibrate significantly improved the renal function as revealed by the significant reductions in urinary albumin excretion and serum levels of creatinine and urea, in addition to the significant increase in creatinine clearance compared with the diabetic control group."1.42Renoprotective Effects of Fenofibrate via Modulation of LKB1/AMPK mRNA Expression and Endothelial Dysfunction in a Rat Model of Diabetic Nephropathy. ( Al-Ajmi, HN; Al-Amin, MA; Al-Rasheed, NM; Attia, HA; Hasan, IH; Mohamad, RA; Sinjilawi, NA, 2015)
"Thermal hyperalgesia and mechanical allodynia were measured using planter test and dynamic aesthesiometer (Ugo-Basile, Italy), respectively."1.38Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats. ( Sharma, PL; Taliyan, R, 2012)
"Treatment with sodium nitrite (NO donor), L: -arginine (NO precursor), daidzein (caveolin inhibitor), and combination of L: -arginine and daidzein for 2 weeks markedly attenuated these changes and increased serum nitrite/nitrate ratio."1.37Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats. ( Arya, A; Sharma, PL; Yadav, HN, 2011)
" In conclusion, while NO bioavailability in mTALs is reduced during diabetes, free radical scavenging with tempol unmasks increased NO production that involves PP2B-dependent activation of NOS1 and NOS2."1.35PP2B-dependent NO production in the medullary thick ascending limb during diabetes. ( Carmines, PK; Foster, JM; Pollock, JS, 2009)
" These results indicate that dietary nitrite is effective in the prevention of early diabetic glomerular injury in which NO bioavailability is impaired."1.34Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats. ( Ishiyama, Y; Kobayashi, J; Muraki, E; Ohtake, K; Uchida, H, 2007)
"Diabetic nephropathy was exacerbated drastically by a nitric oxide synthase inhibitor and mildly by a NO precursor."1.33Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats. ( Higuchi, M; Hora, K; Kamijo, H, 2006)
"Gliclazide treatment, but not glibenclamide, significantly reduced the oxidative products and NAD(P)H oxidase."1.32Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. ( Fujita, T; Goto, A; Onozato, ML; Tojo, A, 2004)
"The rats with diabetic acute renal failure had a much lower creatinine clearance (90 +/- 22 microliters."1.29Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats. ( Blum, M; Cabili, S; Chernihovsky, T; Goor, Y; Iaina, A; Peer, G; Silverberg, D; Wollman, Y, 1996)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's12 (54.55)29.6817
2010's7 (31.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
You, H1
Gao, T1
Cooper, TK1
Morris, SM1
Awad, AS1
Morsy, MA1
Heeba, GH1
Mahmoud, ME1
Al-Rasheed, NM2
Attia, HA1
Al-Amin, MA1
Al-Ajmi, HN1
Hasan, IH1
Mohamad, RA1
Sinjilawi, NA1
Okada, S1
Saito, M1
Kazuyama, E1
Hanada, T1
Kawaba, Y1
Hayashi, A1
Satoh, K1
Kanzaki, S1
Mariee, AD1
Abd-Allah, GM1
El-Yamany, MF1
Foster, JM1
Carmines, PK1
Pollock, JS1
Hsu, BR1
Fu, SH1
Hsu, S1
Chen, ST1
Arya, A1
Yadav, HN1
Sharma, PL2
Taliyan, R1
Imanishi, M1
Okada, N1
Konishi, Y1
Morikawa, T1
Maeda, I1
Kitabayashi, C1
Masada, M1
Shirahashi, N1
Wilcox, CS2
Nishiyama, A1
Palanisamy, N1
Venkataraman, AC1
Hiragushi, K2
Wada, J2
Eguchi, J1
Matsuoka, T1
Yasuhara, A1
Hashimoto, I1
Yamashita, T1
Hida, K1
Nakamura, Y1
Shikata, K2
Minamino, N1
Kangawa, K1
Makino, H2
Onozato, ML2
Tojo, A2
Goto, A2
Fujita, T2
Asaba, K1
Quinn, MT1
Kamijo, H1
Higuchi, M1
Hora, K1
Vareniuk, I1
Pavlov, IA1
Drel, VR1
Lyzogubov, VV1
Ilnytska, O1
Bell, SR1
Tibrewala, J1
Groves, JT1
Obrosova, IG1
Ohtake, K1
Ishiyama, Y1
Uchida, H1
Muraki, E1
Kobayashi, J1
Goor, Y1
Peer, G1
Iaina, A1
Blum, M1
Wollman, Y1
Chernihovsky, T1
Silverberg, D1
Cabili, S1
Trachtman, H2
Futterweit, S2
Crimmins, DL1
Sugimoto, H1
Matsuda, M1
Kushiro, M1
Hayashi, Y1
De Vriese, AS1
Stoenoiu, MS1
Elger, M1
Devuyst, O1
Vanholder, R1
Kriz, W1
Lameire, NH1
Pine, E1
Mann, J1
Valderrama, E1

Trials

1 trial available for nitrites and Diabetic Glomerulosclerosis

ArticleYear
Angiotensin II receptor blockade reduces salt sensitivity of blood pressure through restoration of renal nitric oxide synthesis in patients with diabetic nephropathy.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2013, Volume: 14, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Angiotensin Receptor Antagonists; Biopterins; Blood Pressu

2013

Other Studies

21 other studies available for nitrites and Diabetic Glomerulosclerosis

ArticleYear
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
    American journal of physiology. Renal physiology, 2014, Dec-01, Volume: 307, Issue:11

    Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimenta

2014
Ameliorative effect of eprosartan on high-fat diet/streptozotocin-induced early diabetic nephropathy in rats.
    European journal of pharmacology, 2015, Mar-05, Volume: 750

    Topics: Acrylates; Angiotensin II; Animals; Blood Glucose; Catalase; Cholesterol; Collagen Type IV; Diabetic

2015
Renoprotective Effects of Fenofibrate via Modulation of LKB1/AMPK mRNA Expression and Endothelial Dysfunction in a Rat Model of Diabetic Nephropathy.
    Pharmacology, 2015, Volume: 95, Issue:5-6

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diabeti

2015
Effects of N-hexacosanol on nitric oxide synthase system in diabetic rat nephropathy.
    Molecular and cellular biochemistry, 2008, Volume: 315, Issue:1-2

    Topics: Animals; Diabetic Nephropathies; Fatty Alcohols; Gene Expression Regulation, Enzymologic; Immunoblot

2008
Renal oxidative stress and nitric oxide production in streptozotocin-induced diabetic nephropathy in rats: the possible modulatory effects of garlic (Allium sativum L.).
    Biotechnology and applied biochemistry, 2009, Volume: 52, Issue:Pt 3

    Topics: Analysis of Variance; Animals; Diabetic Nephropathies; Garlic; Glutathione; Kidney; Male; Nitric Oxi

2009
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:2

    Topics: Amidines; Animals; Benzylamines; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclic N-Oxides

2009
Interleukin-1 receptor antagonist enhances islet engraftment without impacting serum levels of nitrite or osteopontin.
    Transplantation proceedings, 2009, Volume: 41, Issue:5

    Topics: Adenoviridae; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA, Complementary;

2009
Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats.
    Molecular and cellular biochemistry, 2011, Volume: 354, Issue:1-2

    Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Body Weight; Caveolin 1; Cholesterol; Collage

2011
Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats.
    Inflammopharmacology, 2012, Volume: 20, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Diabe

2012
Beneficial effect of genistein on lowering blood pressure and kidney toxicity in fructose-fed hypertensive rats.
    The British journal of nutrition, 2013, May-28, Volume: 109, Issue:10

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetic Nephropathies; Diet; Dietary Sucrose; Fru

2013
The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.
    Kidney international, 2004, Volume: 65, Issue:2

    Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blotting, Northern; Cells, Cultured; Diabetes Mellitu

2004
Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet.
    Kidney international, 2004, Volume: 65, Issue:3

    Topics: Animals; Blood Pressure; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Diabetic Nephropathi

2004
Effects of NADPH oxidase inhibitor in diabetic nephropathy.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors;

2005
Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats.
    Nephron. Physiology, 2006, Volume: 104, Issue:1

    Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glom

2006
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
    Experimental neurology, 2007, Volume: 205, Issue:2

    Topics: Anesthesia; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies;

2007
Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats.
    Nitric oxide : biology and chemistry, 2007, Volume: 17, Issue:2

    Topics: Animals; Diabetic Nephropathies; Dietary Supplements; Kidney; Kidney Diseases; Male; Malondialdehyde

2007
Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats.
    Diabetologia, 1996, Volume: 39, Issue:9

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Creatinine; Diabetes Mellitus, Experim

1996
High glucose inhibits nitric oxide production in cultured rat mesangial cells.
    Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:8

    Topics: Amino Acids; Animals; Arginine; Cells, Cultured; Diabetic Nephropathies; Glomerular Mesangium; Gluco

1997
Increased expression of endothelial cell nitric oxide synthase (ecNOS) in afferent and glomerular endothelial cells is involved in glomerular hyperfiltration of diabetic nephropathy.
    Diabetologia, 1998, Volume: 41, Issue:12

    Topics: Animals; Arterioles; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelium, Vascular;

1998
Diabetes-induced microvascular dysfunction in the hydronephrotic kidney: role of nitric oxide.
    Kidney international, 2001, Volume: 60, Issue:1

    Topics: Animals; Blood Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathi

2001
Chronic diabetic nephropathy: role of inducible nitric oxide synthase.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Chronic Disease; Diabetic Nephropathies; Growth; Immunoblotting

2002