nitrites has been researched along with Crush Syndrome in 3 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Crush Syndrome: Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crush syndrome is characterized by ischemia/reperfusion injury (IRI)." | 2.58 | Nitrite as a pharmacological intervention for the successful treatment of crush syndrome. ( Kobayashi, J; Murata, I, 2018) |
| " Nitrite administration to CS rats restored nitric oxide bioavailability by enhancing nitrite levels of the muscle, resulting in a reduction of rhabdomyolysis markers such as potassium, lactate dehydrogenase, and creatine phosphokinase." | 1.38 | Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model. ( Inoue, Y; Kanamoto, I; Kimura, S; Kobayashi, J; Morimoto, Y; Murata, I; Nakano, G; Nozaki, R; Ohtake, K; Ooi, K; Sonoda, K; Uchida, H; Ueda, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, J | 2 |
| Murata, I | 2 |
| Nozaki, R | 1 |
| Ooi, K | 1 |
| Ohtake, K | 1 |
| Kimura, S | 1 |
| Ueda, H | 1 |
| Nakano, G | 1 |
| Sonoda, K | 1 |
| Inoue, Y | 1 |
| Uchida, H | 1 |
| Kanamoto, I | 1 |
| Morimoto, Y | 1 |
| Adachi, J | 1 |
| Morita, S | 1 |
| Yasuda, H | 1 |
| Miwa, A | 1 |
| Ueno, Y | 1 |
| Asano, M | 1 |
| Tatsuno, Y | 1 |
1 review available for nitrites and Crush Syndrome
| Article | Year |
|---|---|
Nitrite as a pharmacological intervention for the successful treatment of crush syndrome.
Topics: Animals; Crush Syndrome; Humans; Ischemic Postconditioning; Muscle, Skeletal; Nitrites | 2018 |
2 other studies available for nitrites and Crush Syndrome
| Article | Year |
|---|---|
Nitrite reduces ischemia/reperfusion-induced muscle damage and improves survival rates in rat crush injury model.
Topics: Analysis of Variance; Animals; Blood Pressure Determination; Crush Syndrome; Disease Models, Animal; | 2012 |
Elevated plasma nitrate in patients with crush syndrome caused by the Kobe earthquake.
Topics: Adult; Chromatography, High Pressure Liquid; Crush Syndrome; Disasters; Female; Humans; Kidney; Male | 1998 |