Page last updated: 2024-10-19

nitrites and Critical Illness

nitrites has been researched along with Critical Illness in 10 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Critical Illness: A disease or state in which death is possible or imminent.

Research Excerpts

ExcerptRelevanceReference
"Fifty-one consecutive children with sepsis and six critically ill children without sepsis were enrolled and given 18 mg/kg antipyrine per NG."3.72Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure. ( Burckart, GJ; Carcillo, JA; Doughty, L; Frye, RF; Kaplan, SS; Kofos, D; Sasser, H, 2003)
"Myocardial infarction was associated with lower whole blood nitrite levels (200+/-53 nmol/L for elevated serum CK MB levels vs 432+/-95 nmol/L in the normal CK MB range, p=0."1.35Serial measurements of whole blood nitrite in an intensive care setting. ( Balzer, J; Heusch, G; Kehmeier, ES; Kelm, M; Kleinbongard, P; Kropp, M; Lauer, T; Lepper, W; Merx, MW; Rassaf, T, 2008)
"Patients with septic shock have a shortage in the availability of arginine associated with a slower production."1.33In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. ( Balasubramanyam, A; Bandi, VP; Gopal, J; Guntupalli, K; Jahoor, F; Villalpando, S, 2006)
"Bone resorption was assessed by measurement of urinary pyridinoline and deoxypyridinoline as a ratio to urinary creatinine."1.31Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production. ( Cuthbertson, B; Harvie, J; Ralston, SH; Robins, S; Smith, LM; Webster, N, 2002)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Jones, GAL1
Eaton, S1
Orford, M1
Ray, S1
Wiley, D1
Ramnarayan, P1
Inwald, D1
Grocott, MPW1
Griksaitis, M1
Pappachan, J1
O'Neill, L1
Mouncey, PR1
Harrison, DA1
Rowan, KM1
Peters, MJ1
Fraga, CM1
Tomasi, CD1
Biff, D1
Topanotti, MF1
Felisberto, F1
Vuolo, F1
Petronilho, F1
Dal-Pizzol, F1
Ritter, C1
Kothari, N1
Bogra, J1
Kohli, M1
Malik, A1
Kothari, D1
Srivastava, S1
Keshari, RS1
Singh, V1
Barthwal, MK1
Dikshit, M1
Alonso de Vega, JM1
Díaz, J1
Serrano, E1
Carbonell, LF1
Carcillo, JA2
Doughty, L1
Kofos, D1
Frye, RF1
Kaplan, SS2
Sasser, H1
Burckart, GJ1
Shiva, S1
Gladwin, MT1
Villalpando, S1
Gopal, J1
Balasubramanyam, A1
Bandi, VP1
Guntupalli, K1
Jahoor, F1
Kehmeier, ES1
Kropp, M1
Kleinbongard, P1
Lauer, T1
Balzer, J1
Merx, MW1
Heusch, G1
Kelm, M1
Lepper, W1
Rassaf, T1
Wong, HR1
Burckart, G1
Smith, LM1
Cuthbertson, B1
Harvie, J1
Webster, N1
Robins, S1
Ralston, SH1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Randomized, Double-blinded, Placebo-controlled Study of N-acetylcysteine Plus Deferoxamine for Patients With Hypotension as Prophylaxis for Acute Renal Failure[NCT00870883]Phase 281 participants (Actual)Interventional2009-03-31Completed
Oxidative Stress Related to 2 Different Oxygen Concentrations During General Anesthesia. Clinical Trial.[NCT02619214]Phase 460 participants (Anticipated)Interventional2013-05-31Recruiting
Impact of Early CRRT Intervention in Patients Receiving VA-ECMO Support on 30-day Mortality: A Randomized Controlled Trial[NCT03549923]Phase 4550 participants (Anticipated)Interventional2018-12-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nitrites and Critical Illness

ArticleYear
Randomization to a Liberal Versus Conservative Oxygenation Target: Redox Responses in Critically Ill Children.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2023, 03-01, Volume: 24, Issue:3

    Topics: Biomarkers; Child; Critical Illness; Humans; Hypoxia; Nitrates; Nitrites; Oxidation-Reduction; Oxyge

2023
The effects of N-acetylcysteine and deferoxamine on plasma cytokine and oxidative damage parameters in critically ill patients with prolonged hypotension: a randomized controlled trial.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:9

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Antioxidants; Critical Illness; Deferoxamine; Doub

2012

Other Studies

8 other studies available for nitrites and Critical Illness

ArticleYear
Role of active nitrogen molecules in progression of septic shock.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:3

    Topics: Adult; APACHE; Creatinine; Critical Care; Critical Illness; Disease Progression; Enzyme-Linked Immun

2012
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure.
    Intensive care medicine, 2003, Volume: 29, Issue:6

    Topics: Adolescent; Age Factors; Analysis of Variance; Antipyrine; Case-Control Studies; Child; Child, Presc

2003
Nitrite therapeutics: back to the future.
    Critical care medicine, 2005, Volume: 33, Issue:8

    Topics: Animals; Critical Illness; Gastric Mucosa; Humans; Nitric Oxide; Nitrites; Stomach

2005
In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:1

    Topics: Adult; Aged; Arginine; Case-Control Studies; Critical Illness; Female; Glomerular Filtration Rate; H

2006
Serial measurements of whole blood nitrite in an intensive care setting.
    Free radical biology & medicine, 2008, Jun-01, Volume: 44, Issue:11

    Topics: Aged; Creatine Kinase, MB Form; Critical Illness; Female; Humans; Intensive Care Units; Kidney Funct

2008
Nitric oxide production in critically ill patients.
    Archives of disease in childhood, 1996, Volume: 74, Issue:6

    Topics: Child; Critical Illness; Graft Rejection; Humans; Infections; Nitrates; Nitric Oxide; Nitrites; Orga

1996
Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production.
    Critical care medicine, 2002, Volume: 30, Issue:4

    Topics: Adult; Aged; Amino Acids; Bone Resorption; Creatinine; Critical Illness; Female; Humans; Intensive C

2002