Page last updated: 2024-10-19

nitrites and Colonic Neoplasms

nitrites has been researched along with Colonic Neoplasms in 34 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
" Dietary additives can suppress the toxic effects of heme iron."2.47Red meat and colon cancer: should we become vegetarians, or can we make meat safer? ( Corpet, DE, 2011)
"Nitrites are a secretory product of activated macrophages and neutrophils of the lamina propria, whereas the lowered luminal pH is due to diminished bicarbonate formation by impaired colonocytes."2.38Nitrite from inflammatory cells--a cancer risk factor in ulcerative colitis? ( Lawson, MJ; Radcliffe, BC; Roediger, WE, 1990)
"Cancer of the colon is subject to somewhat different controlling elements than cancer of the breast because of the nature of the cell kinetics governing these tissues."2.36Mechanism of action of diet as a carcinogen. ( Weisburger, JH, 1979)
"Here, stable overexpression NOS1 of colon cancer cells were constructed to investigate whether NOS1 plays a special role in colon cancer."1.51Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity. ( Chen, J; Chen, X; Gao, W; Huang, M; Li, K; Liu, Q; Wang, Q; Xu, P; Ye, S; Zeng, S; Zhang, Q; Zhong, Z, 2019)
"Lymphomas were seen only at the higher dose when the animals were were young, at the beginning of the test."1.26Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea. ( Maronpot, RR; Narisawa, T; Weisburger, JH; Wong, CQ, 1976)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199011 (32.35)18.7374
1990's10 (29.41)18.2507
2000's5 (14.71)29.6817
2010's8 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vukovic, NL1
Obradovic, AD1
Vukic, MD1
Jovanovic, D1
Djurdjevic, PM1
Wang, Q1
Ye, S1
Chen, X1
Xu, P1
Li, K1
Zeng, S1
Huang, M1
Gao, W1
Chen, J1
Zhang, Q1
Zhong, Z1
Liu, Q1
Miller, PE1
Lazarus, P1
Lesko, SM1
Cross, AJ1
Sinha, R1
Laio, J1
Zhu, J1
Harper, G1
Muscat, JE1
Hartman, TJ1
Chenni, FZ1
Taché, S2
Naud, N2
Guéraud, F2
Hobbs, DA1
Kunhle, GG1
Pierre, FH2
Corpet, DE3
De Boo, S1
Kopecka, J1
Brusa, D1
Gazzano, E1
Matera, L1
Ghigo, D1
Bosia, A1
Riganti, C1
Santarelli, RL1
Vendeuvre, JL1
Viau, M1
Genot, C1
Coulter, JA1
Page, NL1
Worthington, J1
Robson, T1
Hirst, DG1
McCarthy, HO1
Jiang, H1
Tang, Y1
Garg, HK1
Parthasarathy, DK1
Torregrossa, AC1
Hord, NG1
Bryan, NS1
Vermeer, IT1
Henderson, LY1
Moonen, EJ1
Engels, LG1
Dallinga, JW1
van Maanen, JM1
Kleinjans, JC1
Kuniyasu, H1
Yano, S1
Sasaki, T1
Sasahira, T1
Sone, S1
Ohmori, H1
Hogg, N1
Monu, N1
Frey, AB1
Weisburger, JH6
Horn, CL1
Barnes, WS1
Horn, C1
Nauss, KM1
Newberne, PM1
Venitt, S1
Fukumura, D1
Yuan, F1
Endo, M1
Jain, RK1
Thomsen, LL3
Scott, JM1
Topley, P1
Knowles, RG1
Keerie, AJ1
Frend, AJ1
Zilocchi, C1
Stoppacciaro, A1
Chiodoni, C1
Parenza, M1
Terrazzini, N1
Colombo, MP1
Witthöft, T1
Eckmann, L1
Kim, JM1
Kagnoff, MF1
Sugimura, T1
Wynder, EL1
Reddy, BS1
McCoy, GD1
Williams, GM1
Narisawa, T1
Wong, CQ1
Maronpot, RR1
Kälble, T3
Tricker, AR3
Berger, M1
Amelung, F1
Waldherr, R2
Hothorn, L1
Möhring, K3
Staehler, G3
Rewcastle, GW1
Atwell, GJ1
Baguley, BC2
Boyd, M1
Zhuang, L2
Denny, WA1
Ching, LM1
Gavin, JB1
Friedl, P1
Hoang, J1
Roediger, WE1
Lawson, MJ1
Radcliffe, BC1
Berger, MR1
Geiss, H1
Stewart, M1
Burtin, P1
Sabine, MC1

Reviews

7 reviews available for nitrites and Colonic Neoplasms

ArticleYear
Red meat and colon cancer: should we become vegetarians, or can we make meat safer?
    Meat science, 2011, Volume: 89, Issue:3

    Topics: alpha-Tocopherol; Animals; Calcium, Dietary; Cattle; Colonic Neoplasms; Diet; Diet, Vegetarian; Food

2011
Possible genotoxic carcinogens in foods in relation to cancer causation.
    Seminars in oncology, 1983, Volume: 10, Issue:3

    Topics: Animals; Breast Neoplasms; Carbolines; Carcinogens, Environmental; Cattle; Colonic Neoplasms; Cookin

1983
Nutritional modulation of cancer.
    Cancer detection and prevention, 1980, Volume: 3, Issue:2

    Topics: Animals; Carcinogens; Colonic Neoplasms; Diet; Esophageal Neoplasms; Female; Humans; Liver Neoplasms

1980
Mutagens in human faeces. Are they relevant to cancer of the large bowel?
    Mutation research, 1982, Volume: 98, Issue:3

    Topics: Colonic Neoplasms; Diet, Vegetarian; Feces; Female; Humans; Male; Mutagens; Nitrates; Nitrites; Nitr

1982
Mechanism of action of diet as a carcinogen.
    Cancer, 1979, Volume: 43, Issue:5 Suppl

    Topics: Breast Neoplasms; Carcinogens; Colonic Neoplasms; Cooking; Diet; Female; Humans; Male; Meat; Mutagen

1979
Nitrite from inflammatory cells--a cancer risk factor in ulcerative colitis?
    Diseases of the colon and rectum, 1990, Volume: 33, Issue:12

    Topics: Animals; Colitis, Ulcerative; Colon; Colonic Neoplasms; Humans; Hydrogen-Ion Concentration; Macropha

1990
Causes of gastric and esophageal cancer. Possible approach to prevention by vitamin C.
    International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement, 1985, Volume: 27

    Topics: Alcohol Drinking; Animals; Ascorbic Acid; Cerebrovascular Disorders; Colonic Neoplasms; Diet; Esopha

1985

Other Studies

27 other studies available for nitrites and Colonic Neoplasms

ArticleYear
Cytotoxic, proapoptotic and antioxidative potential of flavonoids isolated from propolis against colon (HCT-116) and breast (MDA-MB-231) cancer cell lines.
    Food research international (Ottawa, Ont.), 2018, Volume: 106

    Topics: Antineoplastic Agents; Antioxidants; Apitherapy; Apoptosis; Breast; Breast Neoplasms; Cell Line, Tum

2018
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
    Biochemical and biophysical research communications, 2019, 08-06, Volume: 515, Issue:4

    Topics: Apoptosis; Benzoquinones; Biological Transport; Caspase 3; Cell Line, Tumor; Cisplatin; Colonic Neop

2019
Meat-related compounds and colorectal cancer risk by anatomical subsite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cookin

2013
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinkin

2013
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells.
    Molecular cancer, 2009, Nov-19, Volume: 8

    Topics: Antigen Presentation; Antigens, Neoplasm; Calreticulin; Cell Death; Cell Line, Tumor; Colonic Neopla

2009
Meat processing and colon carcinogenesis: cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:7

    Topics: Animals; Biomarkers; Colonic Neoplasms; Cooking; Diet; Feces; Female; Heme; Meat; Meat-Packing Indus

2010
Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer.
    The journal of gene medicine, 2010, Volume: 12, Issue:9

    Topics: Animals; Antigens, Surface; Apoptosis; Breast Neoplasms; Colonic Neoplasms; Female; Gene Expression

2010
Concentration- and stage-specific effects of nitrite on colon cancer cell lines.
    Nitric oxide : biology and chemistry, 2012, May-15, Volume: 26, Issue:4

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Mice; Neoplasm

2012
Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation.
    Toxicology letters, 2004, Dec-30, Volume: 154, Issue:3

    Topics: Caco-2 Cells; Carcinogens; Colitis; Colonic Neoplasms; DNA Adducts; Humans; Neutrophil Activation; N

2004
Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages.
    The American journal of pathology, 2005, Volume: 166, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Colonic N

2005
Red meat and colon cancer: heme proteins and nitrite in the gut. A commentary on "diet-induced endogenous formation of nitroso compounds in the GI tract".
    Free radical biology & medicine, 2007, Oct-01, Volume: 43, Issue:7

    Topics: Colonic Neoplasms; Diet; Gastrointestinal Tract; Heme; Hemeproteins; Humans; Meat; Nitrites; Nitroso

2007
Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells.
    Cancer research, 2007, Dec-01, Volume: 67, Issue:23

    Topics: Adenocarcinoma; Animals; CD8-Positive T-Lymphocytes; Chromium; Colonic Neoplasms; Cytotoxicity, Immu

2007
Nutrition and cancer: mechanisms of genotoxic and epigenetic carcinogens in nutritional carcinogenesis.
    Bulletin of the New York Academy of Medicine, 1982, Volume: 58, Issue:3

    Topics: Animals; Colonic Neoplasms; Dietary Fats; Female; Humans; Male; Mutation; Neoplasms; Nitrates; Nitri

1982
Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions.
    The American journal of pathology, 1997, Volume: 150, Issue:2

    Topics: Adenocarcinoma; Animals; Capillary Permeability; Colonic Neoplasms; Endothelium, Vascular; Female; H

1997
Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.
    Cancer research, 1997, Aug-01, Volume: 57, Issue:15

    Topics: Adenocarcinoma; Amidines; Animals; Arginine; Benzylamines; Colonic Neoplasms; Enzyme Inhibitors; Hem

1997
Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor.
    The Journal of experimental medicine, 1998, Jul-06, Volume: 188, Issue:1

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Ch

1998
Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Adenocarcinoma; Cell Line; Colon; Colonic Neoplasms; Escherichia coli; Gene Expression Regulation, E

1998
Experimental tumors in digestive organs.
    Gastroenterologia Japonica, 1976, Volume: 11, Issue:3

    Topics: Animals; Azoxymethane; Benz(a)Anthracenes; Colonic Neoplasms; Cricetinae; Dogs; Duodenal Neoplasms;

1976
Diet and gastrointestinal cancer.
    Clinics in gastroenterology, 1976, Volume: 5, Issue:3

    Topics: Alcoholism; Animals; Colonic Neoplasms; Diet; Dietary Carbohydrates; Dietary Fats; Esophageal Neopla

1976
Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Dose-Response Relatio

1976
Tumor induction in a rat model for ureterosigmoidostomy without evidence of nitrosamine formation.
    The Journal of urology, 1991, Volume: 146, Issue:3

    Topics: Adenocarcinoma; Adenoma; Amines; Anastomosis, Surgical; Animals; Colon, Sigmoid; Colonic Neoplasms;

1991
Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:9

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Macrophages; Me

1991
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Methylatio

1991
Ureterosigmoidostomy: long-term results, risk of carcinoma and etiological factors for carcinogenesis.
    The Journal of urology, 1990, Volume: 144, Issue:5

    Topics: Adult; Colon, Sigmoid; Colonic Neoplasms; Follow-Up Studies; Humans; Nitrates; Nitrites; Nitrosamine

1990
The role of nitrate, nitrite and N-nitrosamines in carcinogenesis of colon tumours following ureterosigmoidostomy.
    Urological research, 1990, Volume: 18, Issue:2

    Topics: Animals; Bacteria; Colon; Colonic Neoplasms; Feces; Humans; Nitrates; Nitrites; Nitrosamines; Rats;

1990
Urinary diversion and bowel cancer.
    Annals of the Royal College of Surgeons of England, 1986, Volume: 68, Issue:2

    Topics: Adult; Bacteria; Colon; Colonic Neoplasms; Humans; Ileum; Nitrites; Nitroso Compounds; Prospective S

1986
Inhibition of the non-specific fixation of fluorescent globulins.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1972, Volume: 17, Issue:1

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Colon; Colonic Neoplasms; Deamination; Female; Fetal

1972