Page last updated: 2024-10-19

nitrites and Chemical and Drug Induced Liver Injury

nitrites has been researched along with Chemical and Drug Induced Liver Injury in 54 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
" Previously, we reported that ICKT ameliorates murine concanavalin A (con A)-induced hepatitis via suppression of interferon (IFN)-gamma and interleukin (IL)-12 production."7.76Active ingredients of traditional Japanese (kampo) medicine, inchinkoto, in murine concanavalin A-induced hepatitis. ( Hasegawa, T; Kase, Y; Makino, B; Mase, A; Takeda, S; Tsuchiya, N; Yamamoto, M, 2010)
" The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days."5.36Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
" Accordingly, this study investigated the influence of the novel JAK inhibitor ruxolitinib (RXB) on concanavalin A (Con A)-induced hepatitis and systemic hyperinflammation in mice to simulate the context occurring in COVID-19 patients."4.12The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice. ( El-Mesery, M; Hazem, SH; Hendawy, OM; Shaker, ME, 2022)
"The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure."3.79The involvement of heme oxygenase 1 but not nitric oxide synthase 2 in a hepatoprotective action of quercetin in lipopolysaccharide-induced hepatotoxicity of D-galactosamine sensitized rats. ( Canová, NK; Farghali, H; Hořínek, A; Lekić, N, 2013)
" Ozone therapy (OT) is shown to reduce inflammation and necrosis in several entities."3.78The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury. ( Akgul, EO; Cakir, E; Cayci, T; Demirbag, S; Eyi, YE; Gul, H; Kaldirim, U; Korkmaz, A; Macit, E; Oter, S; Ozler, M; Oztas, E; Topal, T; Toygar, M; Uysal, B; Yaman, H; Yildirim, AO, 2012)
"Atorvastatin prevented mucosal damage and inflammation associated with 5-FU-induced OM, but the association of a higher dose of ATV with 5-FU induced hepatotoxicity and amplified leukopenia."3.77Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis. ( Alencar, NM; Barboza, DR; Brito, GA; Gomes, AS; Leitão, RF; Macedo, RN; Medeiros, CA; Nogueira, NA; Ribeiro, RA, 2011)
" Previously, we reported that ICKT ameliorates murine concanavalin A (con A)-induced hepatitis via suppression of interferon (IFN)-gamma and interleukin (IL)-12 production."3.76Active ingredients of traditional Japanese (kampo) medicine, inchinkoto, in murine concanavalin A-induced hepatitis. ( Hasegawa, T; Kase, Y; Makino, B; Mase, A; Takeda, S; Tsuchiya, N; Yamamoto, M, 2010)
"Mice sensitized with D-galactosamine (GalN) and challenged with recombinant murine tumor necrosis factor alpha (TNF alpha) developed severe apoptotic and secondary necrotic liver injury as assessed by histology, measurement of cytosolic DNA fragments, and determination of liver specific enzymes in plasma."3.69Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways. ( Barsig, J; Bohlinger, I; Leist, M; Tiegs, G; Uhlig, S; Wendel, A, 1995)
"Oxidative stress, liver fibrosis and angiogenesis may be implicated in n-TiO2-induced liver toxicity."1.42Potential antifibrotic and angiostatic impact of idebenone, carnosine and vitamin E in nano-sized titanium dioxide-induced liver injury. ( Abdelazim, SA; Ali, SA; Darwish, HA; Kadry, MO; Rizk, MZ, 2015)
"Cornuside treatment inhibited the formation of liver nitrite, and reduced the overexpression of iNOS and COX-2 proteins, but restored the liver CYP2E1 content as compared with the CCl₄-treated rats."1.37Protective effect of cornuside against carbon tetrachloride-induced acute hepatic injury. ( Choi, YH; Jin, GY; Li, GZ; Song, SZ; Yan, GH, 2011)
" Catechin (50 mg/Kg) was co-supplemented after 4 weeks of alcohol treatment till the end of the dosing period."1.37Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model. ( Bharrhan, S; Chopra, K; Koul, A; Rishi, P, 2011)
" The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days."1.36Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity. ( Anuradha, CV; Pooranaperundevi, M; Sumiyabanu, MS; Sundarapandiyan, R; Viswanathan, P, 2010)
"Scutellarin is a natural compound from a Chinese herb."1.34The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice. ( Liu, GT; Tan, ZH; Wei, HL; Yu, LH, 2007)
"Hesperidin (HDN) is a flavanone glycoside abundantly found in citrus fruits."1.33Beneficial effect of hesperidin on lipopolysaccharide-induced hepatotoxicity. ( Chopra, K; Kaur, G; Tirkey, N, 2006)
" The protection offered by arabic gum does not appear to be caused by a decrease in the formation of toxic acetaminophen metabolites, which consumes glutathione, because arabic gum did not alter acetaminophen-induced hepatic glutathione depletion."1.32Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice. ( Al-Bekairi, AM; Al-Shabanah, OA; Gamal el-din, AM; Mostafa, AM; Nagi, MN, 2003)
"The aim of this work was to determine if the inhibition or stimulation of NO synthesis modulates liver damage induced by the chronic administration of CCl4."1.30Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. ( Muriel, P, 1998)
"Sodium nitrite pretreatment also enhanced the carbon tetrachloride-induced decrease in hepatic microsomal glucose-6-phosphatase activity."1.26Enhanced hepatotoxicity of carbon tetrachloride following sodium nitrite pretreatment. ( Bhonsle, P; Suarez, KA, 1978)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199015 (27.78)18.7374
1990's4 (7.41)18.2507
2000's16 (29.63)29.6817
2010's17 (31.48)24.3611
2020's2 (3.70)2.80

Authors

AuthorsStudies
Shaker, ME1
Hendawy, OM1
El-Mesery, M1
Hazem, SH1
Oğuz Cumaoğlu, M1
Cumaoğlu, B1
Tekin, Y1
Günay, N1
Park, CH1
Shin, MR1
An, BK1
Joh, HW1
Lee, JC1
Roh, SS1
Yokozawa, T1
Lekić, N1
Canová, NK1
Hořínek, A1
Farghali, H1
Parikh, R1
Dalwadi, S1
Aboti, P1
Patel, L1
Abdelazim, SA1
Darwish, HA1
Ali, SA1
Rizk, MZ1
Kadry, MO1
Yokoyama, S1
Hiramoto, K1
Koyama, M1
Ooi, K1
Omar, HA1
Mohamed, WR1
Arafa, el-SA1
Shehata, BA1
El Sherbiny, GA1
Arab, HH1
Elgendy, AN1
Wang, CC1
Cheng, PY1
Peng, YJ1
Wu, ES1
Wei, HP1
Yen, MH1
Quan, J1
Piao, L1
Wang, X1
Li, T1
Yin, X1
Radosavljević, T1
Mladenović, D1
Jakovljević, V1
Vucvić, D1
Rasć-Marković, A1
Hrncić, D1
Djuric, D1
Stanojlović, O1
Zhu, JH1
McClung, JP1
Zhang, X1
Aregullin, M1
Chen, C1
Gonzalez, FJ1
Kim, TW1
Lei, XG1
Mase, A1
Makino, B1
Tsuchiya, N1
Yamamoto, M1
Kase, Y1
Takeda, S1
Hasegawa, T1
Pooranaperundevi, M1
Sumiyabanu, MS1
Viswanathan, P1
Sundarapandiyan, R1
Anuradha, CV1
Srinivasan, P1
Li, YH1
Hsu, DZ2
Su, SB1
Liu, MY2
Medeiros, CA1
Leitão, RF1
Macedo, RN1
Barboza, DR1
Gomes, AS1
Nogueira, NA1
Alencar, NM1
Ribeiro, RA1
Brito, GA1
Song, SZ1
Choi, YH1
Jin, GY1
Li, GZ1
Yan, GH1
Nicholson, SS1
Bharrhan, S1
Koul, A1
Chopra, K2
Rishi, P1
Engin, AB1
Bukan, N1
Kurukahvecioglu, O1
Memis, L1
Engin, A1
Lu, Y1
Leung, TM1
Ward, SC1
Nieto, N1
Gul, H1
Uysal, B1
Cakir, E1
Yaman, H1
Macit, E1
Yildirim, AO1
Eyi, YE1
Kaldirim, U1
Oztas, E1
Akgul, EO1
Cayci, T1
Ozler, M1
Topal, T1
Oter, S1
Korkmaz, A1
Toygar, M1
Demirbag, S1
Chtourou, Y1
Garoui, E1
Boudawara, T1
Zeghal, N1
Gamal el-din, AM1
Mostafa, AM1
Al-Shabanah, OA1
Al-Bekairi, AM1
Nagi, MN1
Kamanaka, Y1
Kawabata, A1
Matsuya, H1
Taga, C1
Sekiguchi, F1
Kawao, N1
Chiang, PJ1
Chien, SP1
Huang, BM1
Sun, Y1
Liu, J1
Qian, F1
Xu, Q1
Salhanick, SD1
Orlow, D1
Holt, DE1
Pavlides, S1
Reenstra, W1
Buras, JA1
Zhao, Y1
Li, H1
Gao, Z1
Gong, Y1
Xu, H1
Wang, Y1
Mei, Y1
Feng, D1
Xu, L1
Kaur, G1
Tirkey, N1
Tan, ZH1
Yu, LH1
Wei, HL1
Liu, GT1
Al-Majed, AA1
Abdel-Zaher, AO1
Abdel-Hady, RH1
Mahmoud, MM1
Farrag, MM1
Alarcón Zurita, A1
Pizá, C1
Morey, A1
Marco, JE1
Bestard, J1
Mairata, S1
Bohlinger, I1
Leist, M1
Barsig, J1
Uhlig, S1
Tiegs, G1
Wendel, A1
Cuzzocrea, S1
Zingarelli, B1
Costantino, G1
Caputi, AP1
Muriel, P1
Tanaka, N1
Tanaka, K1
Nagashima, Y1
Kondo, M1
Sekihara, H1
Futter, LE1
al-Swayeh, OA1
Moore, PK1
Bailey, K1
Chow, AY1
Downie, RH1
Pike, RK1
Mirvish, SS1
Suarez, KA1
Bhonsle, P1
Astill, BD1
Mulligan, LT1
Kamm, JJ2
Dashman, T2
Newmark, H1
Mergens, WJ1
Conney, AH1
Burns, JJ1
Bogdanov, NA1
Gembitskiĭ, EV1
Bonitenko, IuIu1
Kasianov, NI1
Pankow, D1
Ponsold, W1
Greenblatt, M1
Montesano, R1
Bartsch, H1
Brésil, H1
Asahina, S1
Friedman, MA1
Arnold, E1
Millar, GN1
Mishkin, M1
Bishop, Y1
Epstein, SS1
Carter, RL1
Ender, F1
Havre, GN1
Madsen, R1
Ceh, L1
Helgebostad, A1
Sakshaug, J1
Sögnen, E1
Hansen, MA1
Koppang, N1

Reviews

1 review available for nitrites and Chemical and Drug Induced Liver Injury

ArticleYear
Formation of N-nitroso compounds: chemistry, kinetics, and in vivo occurrence.
    Toxicology and applied pharmacology, 1975, Volume: 31, Issue:3

    Topics: Animals; Bacteria; Cats; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Fema

1975

Other Studies

53 other studies available for nitrites and Chemical and Drug Induced Liver Injury

ArticleYear
The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice.
    International immunopharmacology, 2022, Volume: 103

    Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokine Release Syndrom

2022
Therapeutic effect of 6-shogaol on acetaminophen-induced hepatotoxicity in mice: an experimental study.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:20

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical

2022
Heat-Processed Scutellariae Radix Protects Hepatic Inflammation through the Amelioration of Oxidative Stress in Lipopolysaccharide-Induced Mice.
    The American journal of Chinese medicine, 2017, Volume: 45, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Che

2017
The involvement of heme oxygenase 1 but not nitric oxide synthase 2 in a hepatoprotective action of quercetin in lipopolysaccharide-induced hepatotoxicity of D-galactosamine sensitized rats.
    Fitoterapia, 2013, Volume: 87

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Galactosamine; Heme Oxygenase-1; Lipo

2013
Inhaled microparticles of antitubercular antibiotic for in vitro and in vivo alveolar macrophage targeting and activation of phagocytosis.
    The Journal of antibiotics, 2014, Volume: 67, Issue:5

    Topics: Administration, Inhalation; Aerosols; Animals; Antitubercular Agents; Bronchoalveolar Lavage Fluid;

2014
Potential antifibrotic and angiostatic impact of idebenone, carnosine and vitamin E in nano-sized titanium dioxide-induced liver injury.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:6

    Topics: Alanine Transaminase; Angiogenesis Inhibitors; Animals; Antioxidants; Aspartate Aminotransferases; C

2015
Chronic liver injury in mice promotes impairment of skin barrier function via tumor necrosis factor-alpha.
    Cutaneous and ocular toxicology, 2016, Volume: 35, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

2016
Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:2

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Aspartate Aminotransferases; Che

2016
Naltrexone protects against lipopolysaccharide/D-galactosamine-induced hepatitis in mice.
    Journal of pharmacological sciences, 2008, Volume: 108, Issue:3

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Inju

2008
Rossicaside B protects against carbon tetrachloride-induced hepatotoxicity in mice.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:6

    Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disaccharides;

2009
Oxidative stress in liver and red blood cells in acute lindane toxicity in rats.
    Human & experimental toxicology, 2009, Volume: 28, Issue:12

    Topics: Animals; Chemical and Drug Induced Liver Injury; Erythrocytes; Hexachlorocyclohexane; Insecticides;

2009
Comparative impacts of knockouts of two antioxidant enzymes on acetaminophen-induced hepatotoxicity in mice.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Inju

2009
Active ingredients of traditional Japanese (kampo) medicine, inchinkoto, in murine concanavalin A-induced hepatitis.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Animals; Artemisia; Chemical and Drug Induced Liver Injury; Chromones; Concanavalin A; Cytokines; Di

2010
Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity.
    Toxicology and industrial health, 2010, Volume: 26, Issue:2

    Topics: Analysis of Variance; Animals; Biomarkers; Blood Glucose; Carbon Tetrachloride; Carbon Tetrachloride

2010
Ostensibly ineffectual doses of cadmium and lipopolysaccharide causes liver damage in rats.
    Human & experimental toxicology, 2011, Volume: 30, Issue:7

    Topics: Animals; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Drug Synergism; Glutathione Perox

2011
Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Atorvastatin; Bac

2011
Protective effect of cornuside against carbon tetrachloride-induced acute hepatic injury.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:4

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase

2011
Southeastern plants toxic to ruminants.
    The Veterinary clinics of North America. Food animal practice, 2011, Volume: 27, Issue:2

    Topics: Anemia, Aplastic; Animal Diseases; Animal Feed; Animal Husbandry; Animals; Central Nervous System Di

2011
Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Alcohols; Animals; Antioxidants; Catechin; Cell Nucleus; Chemical and Drug Induced Liver Injury; Dis

2011
Effect of butylated hydroxytoluene (E321) pretreatment versus L-arginine on liver injury after sub-lethal dose of endotoxin administration.
    Environmental toxicology and pharmacology, 2011, Volume: 32, Issue:3

    Topics: Animals; Arginine; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Dose-Response R

2011
Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Alanine Transaminase; Animals; Apoptosis; Arginine; Argininosuccinate Synthase; Aspartate Aminotrans

2012
The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases;

2012
Therapeutic efficacy of silymarin from milk thistle in reducing manganese-induced hepatic damage and apoptosis in rats.
    Human & experimental toxicology, 2013, Volume: 32, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; DNA Damage; Lipid Peroxida

2013
Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice.
    Pharmacological research, 2003, Volume: 48, Issue:6

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspart

2003
Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat.
    Life sciences, 2003, Dec-26, Volume: 74, Issue:6

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amidines; Analgesics, Non-Narcotic; Anima

2003
Parenteral sesame oil attenuates oxidative stress after endotoxin intoxication in rats.
    Toxicology, 2004, Mar-01, Volume: 196, Issue:1-2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Cata

2004
Nitric oxide inhibits T cell adhesion and migration by down-regulation of beta1-integrin expression in immunologically liver-injured mice.
    International immunopharmacology, 2006, Volume: 6, Issue:4

    Topics: Animals; Cell Adhesion; Cell Movement; Chemical and Drug Induced Liver Injury; Coculture Techniques;

2006
Endothelially derived nitric oxide affects the severity of early acetaminophen-induced hepatic injury in mice.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2006, Volume: 13, Issue:5

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Disease Models

2006
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Dose-Response Rela

2006
(-)-Epigallocatechin-3-gallate protects mice from concanavalin A-induced hepatitis through suppressing immune-mediated liver injury.
    Clinical and experimental immunology, 2006, Volume: 145, Issue:3

    Topics: Alanine Transaminase; Animals; Apoptosis; Catechin; Chemical and Drug Induced Liver Injury; Chemokin

2006
Beneficial effect of hesperidin on lipopolysaccharide-induced hepatotoxicity.
    Toxicology, 2006, Sep-21, Volume: 226, Issue:2-3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Hesperidin; Lipopolysaccharides; Liver

2006
The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Alanine Transaminase; Animals; Apigenin; Aspartate Aminotransferases; Chemical and Drug Induced Live

2007
Carnitine deficiency provokes cisplatin-induced hepatotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:3

    Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti

2007
The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage.
    Toxicology, 2008, Jan-20, Volume: 243, Issue:3

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidan

2008
[Acute kidney failure caused by nitrite poisoning].
    Revista clinica espanola, 1981, Apr-25, Volume: 161, Issue:1

    Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Nitrites; N

1981
Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; DNA; Drug Tolerance; Galactosamine; Huma

1995
Protective effect of melatonin in a non-septic shock model induced by zymosan in the rat.
    Journal of pineal research, 1998, Volume: 25, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte;

1998
Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride.
    Biochemical pharmacology, 1998, Sep-15, Volume: 56, Issue:6

    Topics: Animals; Arginine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Drug Inte

1998
Nitric oxide increases hepatic arterial blood flow in rats with carbon tetrachloride-induced acute hepatic injury.
    Gastroenterology, 1999, Volume: 117, Issue:1

    Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzyme Inhibit

1999
A comparison of the effect of nitroparacetamol and paracetamol on liver injury.
    British journal of pharmacology, 2001, Volume: 132, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biomarkers; Chemical and Drug Induced Liver Injury

2001
1-Piperidinocyclohexanecarbonitrile, a toxic precursor of phencyclidine.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Kidney Diseases; Lethal Dose 50; Male; Mice; Nitril

1976
Enhanced hepatotoxicity of carbon tetrachloride following sodium nitrite pretreatment.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 234, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drug Synergism; Hyp

1978
Phenolic antioxidants and the inhibition of hepatotoxicity from N-dimethylnitrosamine formed in situ in the rat stomach.
    Food and cosmetics toxicology, 1977, Volume: 15, Issue:3

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Chemical an

1977
Inhibition of amine-nitrite hepatotoxicity by alpha-tocopherol.
    Toxicology and applied pharmacology, 1977, Volume: 41, Issue:3

    Topics: Alanine Transaminase; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Male; Nitrites;

1977
Effect of ascorbic acid on amine-nitrite toxicity.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; D

1975
[Complications and after effects of acute inhalation poisoning by substances with suffocating-irritating action].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:2

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Gastrointestinal Diseases; Humans; Mal

1976
Effect of methemoglobinemia on carbon tetrachloride heaptoxicity.
    Toxicology and applied pharmacology, 1976, Volume: 36, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Alanine Transaminase; Aniline Compounds; Animals; Carbon Tetrachlorid

1976
Brief communication: ascorbic acid blocking of aminopyrine nitrosation in NZO-B1 mice.
    Journal of the National Cancer Institute, 1973, Volume: 50, Issue:4

    Topics: Aminopyrine; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Liver; Male; Mice; Mice

1973
Nitrosation of d-N,N'-bis(1-hydroxymethylpropyl)ethylenediamine, an antitubercular drug.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:3

    Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Ethyle

1974
Acute synergistic toxicity and hepatic necrosis following oral administration of sodium nitrite and secondary amines to mice.
    Cancer research, 1971, Volume: 31, Issue:9

    Topics: Administration, Oral; Amines; Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Mice;

1971
Some implications of hepatic veno-occlusive disease.
    Pathologia et microbiologia, 1970, Volume: 35, Issue:1

    Topics: Alkaloids; Animal Feed; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Fish Products;

1970
Studies on conditions under which N-nitrosodimethylamine is formed in herring meal produced from nitrite-preserved herring. The risk of using nitrite uncritically as a preservative agent.
    Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde, 1967, Volume: 22, Issue:3

    Topics: Animal Feed; Animals; Chemical and Drug Induced Liver Injury; Fish Products; Food Preservation; Mink

1967
Dimethylnitrosamine; its hepatotoxic effect in sheep and its occurrence in toxic batches of herring meal.
    Nature, 1965, Jun-19, Volume: 206, Issue:990

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

1965