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nitrites and Chagas Disease

nitrites has been researched along with Chagas Disease in 14 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.

Research Excerpts

ExcerptRelevanceReference
"Gastritis is a common ailment that can be caused by poor dietary habits, intake of alcohol or other gastric irritants, bacterial infection, or by the widespread use of non-steroidal anti-inflammatory drugs (NSAIDs)."1.43Aspirin treatment exacerbates oral infections by Trypanosoma cruzi. ( Cossentini, LA; Da Silva, RV; De Almeida Araújo, EJ; Pinge-Filho, P; Yamada-Ogatta, SF; Yamauchi, LM, 2016)
"In the megaesophagus of Chagas' disease, chronic esophagitis is caused by stasis of swallowed food and saliva."1.34Larger amounts of nitrite and nitrate-reducing bacteria in megaesophagus of Chagas' disease than in controls. ( Cecconello, I; Dos Santos, MA; Gama-Rodrigues, JJ; Pajecki, D; Yagi, OK; Zilberstein, B, 2007)
"In vehicle-treated rats, Trypanosoma cruzi infection increased the cardiac levels of TNF-alpha, IFN-gamma and IL-10, at day 9 post inoculation, and the TNF-alpha remained elevated until day 13."1.33Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats. ( Barcellos, L; Camargos, ER; Chiari, E; Huang, H; Machado, CR; Marques, CA; Rachid, MA; Tanowitz, HB; Teixeira, MM, 2006)
"Control of the acute phase of Trypanosoma cruzi infections is critically dependent on cytokine-mediated macrophage activation to intracellular killing."1.29Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection. ( Abrahamsohn, IA; Coffman, RL, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's5 (35.71)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Canavaci, AM1
Sorgi, CA1
Martins, VP1
Morais, FR1
de Sousa, ÉV1
Trindade, BC1
Cunha, FQ3
Rossi, MA1
Aronoff, DM1
Faccioli, LH1
Nomizo, A1
Cossentini, LA1
Da Silva, RV1
Yamada-Ogatta, SF1
Yamauchi, LM1
De Almeida Araújo, EJ1
Pinge-Filho, P1
Santos, CD1
Loria, RM1
Oliveira, LG1
Kuehn, CC1
Toldo, MP1
Albuquerque, S1
do Prado, JC1
Rezende-Oliveira, K1
Sarmento, RR1
Rodrigues, V1
Castro, DP1
Moraes, CS1
Gonzalez, MS1
Ratcliffe, NA1
Azambuja, P1
Garcia, ES1
Planelles, L1
Thomas, MC1
Marañón, C1
Morell, M1
López, MC1
Pascutti, MF1
Bottasso, OA1
Hourquescos, MC1
Wietzerbin, J2
Revelli, S2
Rachid, MA1
Camargos, ER1
Barcellos, L1
Marques, CA1
Chiari, E1
Huang, H1
Tanowitz, HB1
Teixeira, MM1
Machado, CR1
Pajecki, D1
Zilberstein, B1
Cecconello, I1
Dos Santos, MA1
Yagi, OK1
Gama-Rodrigues, JJ1
Gutierrez, FR1
Lalu, MM1
Mariano, FS1
Milanezi, CM1
Cena, J1
Gerlach, RF1
Santos, JE1
Torres-Dueñas, D1
Schulz, R1
Silva, JS2
Vespa, GN1
Abrahamsohn, IA1
Coffman, RL1
de Oliveira, L1
Borges, MM1
Leal, RC1
Assreuy, J1
Kloetzel, JK1
Le Page, C1
Piaggio, E1
Bottasso, O1

Other Studies

14 other studies available for nitrites and Chagas Disease

ArticleYear
The acute phase of Trypanosoma cruzi infection is attenuated in 5-lipoxygenase-deficient mice.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Arachidonate 5-Lipoxygenase; Chagas Disease; Enzyme-Linked Immunosorbent Assay; Flow Cytome

2014
Aspirin treatment exacerbates oral infections by Trypanosoma cruzi.
    Experimental parasitology, 2016, Volume: 164

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Beverages; Chagas Disease; Dietary Carboh

2016
Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains.
    Immunobiology, 2010, Volume: 215, Issue:12

    Topics: Acute Disease; Animals; Chagas Disease; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; I

2010
Production of cytokine and chemokines by human mononuclear cells and whole blood cells after infection with Trypanosoma cruzi.
    Revista da Sociedade Brasileira de Medicina Tropical, 2012, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Animals; Blood Cells; Chagas Disease; Chemokines; Chlorocebus aethiops; Cytokines

2012
Trypanosoma cruzi immune response modulation decreases microbiota in Rhodnius prolixus gut and is crucial for parasite survival and development.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Chagas Disease; Immunity, Humoral; Intestinal Mucosa; Intestines; Me

2012
Differential CD86 and CD40 co-stimulatory molecules and cytokine expression pattern induced by Trypanosoma cruzi in APCs from resistant or susceptible mice.
    Clinical and experimental immunology, 2003, Volume: 131, Issue:1

    Topics: Animals; Antigen-Presenting Cells; B7-1 Antigen; CD3 Complex; CD40 Antigens; Chagas Disease; Cytokin

2003
Age-related increase in resistance to acute Trypanosoma cruzi infection in rats is associated with an appropriate antibody response.
    Scandinavian journal of immunology, 2003, Volume: 58, Issue:2

    Topics: Age Factors; Animals; Antibodies, Protozoan; Chagas Disease; Hemolysis; Immunity, Innate; Interferon

2003
Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats.
    Microbes and infection, 2006, Volume: 8, Issue:8

    Topics: Animal Structures; Animals; Bosentan; Chagas Disease; Chemokines; Cytokines; Diaphragm; Disease Mode

2006
Larger amounts of nitrite and nitrate-reducing bacteria in megaesophagus of Chagas' disease than in controls.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2007, Volume: 11, Issue:2

    Topics: Adult; Aged; Bacteria; Chagas Disease; Esophageal Achalasia; Esophagus; Female; Humans; Male; Middle

2007
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.
    The Journal of infectious diseases, 2008, May-15, Volume: 197, Issue:10

    Topics: Animals; Chagas Disease; Cytokines; Female; Gene Expression Profiling; Matrix Metalloproteinase 2; M

2008
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro.
    Infection and immunity, 1994, Volume: 62, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chagas Disease; Mice; Mice, Inbred BALB C; Mice, Inbr

1994
Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection.
    Experimental parasitology, 1996, Volume: 84, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; Chagas Disease; Dendritic Cells; Female; Immunity,

1996
Nitric oxide involvement in experimental Trypanosoma cruzi infection in Calomys callosus and Swiss mice.
    Parasitology research, 1997, Volume: 83, Issue:8

    Topics: Animals; Arvicolinae; Cells, Cultured; Chagas Disease; Hydrogen Peroxide; Immunity, Innate; Macropha

1997
Benznidazole, a drug employed in the treatment of Chagas' disease, down-regulates the synthesis of nitrite and cytokines by murine stimulated macrophages.
    Clinical and experimental immunology, 1999, Volume: 118, Issue:2

    Topics: Animals; Cell Line; Chagas Disease; Cytokines; Down-Regulation; Gene Expression Regulation, Enzymolo

1999