nitrites has been researched along with Cerebral Malaria in 10 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether iron chelation modulates nitric oxide (NO) formation and cell-mediated immune effector function in children with cerebral malaria, serum concentrations were measured of the stable end products of NO, nitrite and nitrate (NO2-/NO3-), interleukin (IL)-4, -6, and -10, and neopterin in 39 Zambian children enrolled in a placebo-controlled trial of desferrioxamine B and quinine therapy." | 5.08 | Modulatory potential of iron chelation therapy on nitric oxide formation in cerebral malaria. ( Gordeuk, VR; Herold, M; Mabeza, G; Thuma, PE; Weiss, G; Werner, ER, 1997) |
| " Here we have tested this high NO bioavailability hypothesis in the setting of experimental cerebral malaria (ECM), but find instead that low NO bioavailability contributes to the genesis of ECM." | 1.33 | Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria. ( Contreras, R; Frangos, JA; Gramaglia, I; Intaglietta, M; Meays, D; Nolan, JP; Sobolewski, P; van der Heyde, HC, 2006) |
| "The pathogenesis of cerebral malaria is poorly understood." | 1.31 | Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism? ( Crawley, J; Dobbie, M; Marsh, K; Surtees, R; Waruiru, C, 2000) |
| "The main clinical presentations in cerebral malaria patients were fever (76." | 1.30 | Plasma levels of nitric oxide in association with severe Plasmodium falciparum in Yemen. ( Abd-Allah, SH; Agina, AA, 1999) |
| "Autoimmune disease is generally rare in tropical rural populations." | 1.29 | Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa? ( al-Yaman, FM; Clark, IA; Cowden, WB; Rockett, KA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhangadamajhi, G | 1 |
| Mohapatra, BN | 1 |
| Kar, SK | 1 |
| Ranjit, M | 1 |
| Agina, AA | 1 |
| Abd-Allah, SH | 1 |
| Cramer, JP | 1 |
| Nüssler, AK | 1 |
| Ehrhardt, S | 1 |
| Burkhardt, J | 1 |
| Otchwemah, RN | 1 |
| Zanger, P | 1 |
| Dietz, E | 1 |
| Gellert, S | 1 |
| Bienzle, U | 1 |
| Mockenhaupt, FP | 1 |
| Gramaglia, I | 1 |
| Sobolewski, P | 1 |
| Meays, D | 1 |
| Contreras, R | 1 |
| Nolan, JP | 1 |
| Frangos, JA | 1 |
| Intaglietta, M | 1 |
| van der Heyde, HC | 1 |
| Clark, IA | 2 |
| Cowden, WB | 2 |
| Rockett, KA | 2 |
| Asensio, VC | 1 |
| Oshima, H | 1 |
| Falanga, PB | 1 |
| al-Yaman, FM | 1 |
| Weiss, G | 1 |
| Thuma, PE | 1 |
| Mabeza, G | 1 |
| Werner, ER | 1 |
| Herold, M | 1 |
| Gordeuk, VR | 1 |
| Dobbie, M | 1 |
| Crawley, J | 1 |
| Waruiru, C | 1 |
| Marsh, K | 1 |
| Surtees, R | 1 |
| Haque, A | 1 |
| Echchannaoui, H | 1 |
| Seguin, R | 1 |
| Schwartzman, J | 1 |
| Kasper, LH | 1 |
| Haque, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819] | 256 participants (Anticipated) | Observational | 2021-01-02 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nitrites and Cerebral Malaria
| Article | Year |
|---|---|
Modulatory potential of iron chelation therapy on nitric oxide formation in cerebral malaria.
Topics: Biopterins; Chelation Therapy; Child; Child, Preschool; Deferoxamine; Double-Blind Method; Humans; I | 1997 |
9 other studies available for nitrites and Cerebral Malaria
| Article | Year |
|---|---|
Endothelial nitric oxide synthase gene polymorphisms and Plasmodium falciparum infection in Indian adults.
Topics: Adult; Animals; Gene Frequency; Haplotypes; Humans; Immunity, Innate; India; Malaria; Malaria, Cereb | 2009 |
Plasma levels of nitric oxide in association with severe Plasmodium falciparum in Yemen.
Topics: Adolescent; Adult; Animals; Child; Female; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Mid | 1999 |
Age-dependent effect of plasma nitric oxide on parasite density in Ghanaian children with severe malaria.
Topics: Age Factors; Anemia; Animals; Child; Child, Preschool; Female; Genotype; Ghana; Humans; Infant; Mala | 2005 |
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.
Topics: Alkenes; Animals; Arginine; Blood Pressure; Capillary Permeability; Cyclic GMP; Hemoglobins; Malaria | 2006 |
Nitric oxide in cerebral malaria.
Topics: Animals; Cameroon; Child; Coma; Diet; Humans; Malaria, Cerebral; Nitrates; Nitric Oxide; Nitrites | 1995 |
Plasmodium berghei: is nitric oxide involved in the pathogenesis of mouse cerebral malaria?
Topics: Animals; Arginine; Disease Susceptibility; Malaria, Cerebral; Mice; Mice, Inbred Strains; Nitrates; | 1993 |
Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa?
Topics: Africa; Autoimmune Diseases; Humans; Immune Tolerance; Immunosuppression Therapy; Macrophages; Malar | 1996 |
Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?
Topics: Antimalarials; Biopterins; Brain; Child; Child, Preschool; Chromatography, High Pressure Liquid; End | 2000 |
Cerebral malaria in mice: interleukin-2 treatment induces accumulation of gammadelta T cells in the brain and alters resistant mice to susceptible-like phenotype.
Topics: Animals; Antibodies, Monoclonal; Blood Vessels; Brain; Cytokines; Drug Resistance; Female; Genetic P | 2001 |