nitrites has been researched along with Cerebral Ischemia in 49 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrites and BDNF may represent potential biomarkers for cortisol negative effects on the area of cerebral ischemia and penumbra, potentiating ischemic cell damage." | 7.85 | Potential Biomarkers with Plasma Cortisol, Brain-derived Neurotrophic Factor and Nitrites in Patients with Acute Ischemic Stroke. ( Casas, S; De Nicola, AF; Folgueira, A; Gargiulo-Monachelli, GM; Gonzalez Deniselle, MC; Lopez, J; Mattiazzi, M; Perez, AF, 2017) |
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 7.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia." | 7.79 | Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013) |
| "Treatment of Valsartan attenuated cerebral injury, potentiated the neuroprotective response of iPoCo in normal rats, and also restored the blunted neuroprotective effect of iPoCo in HFD-treated rats along with enhanced Nrf-2 levels." | 5.91 | Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury. ( Jaggi, AS; Kaur, S; Kumar, K; Singh, N, 2023) |
| "Valproic acid (VA) is an antiepileptic that is also used for the treatment of bipolar disorders." | 5.48 | Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions. ( Correia, AO; Costa, RO; da Silva Ribeiro, AE; de Barros Viana, GS; de Siqueira, KP; Dos Santos, GCA; Lima, DGS; Lucetti, DL; Lucetti, ECP; Moura, JA; Neves, KRT; Parente, LLT; Silva, MR, 2018) |
| "Nitrites and BDNF may represent potential biomarkers for cortisol negative effects on the area of cerebral ischemia and penumbra, potentiating ischemic cell damage." | 3.85 | Potential Biomarkers with Plasma Cortisol, Brain-derived Neurotrophic Factor and Nitrites in Patients with Acute Ischemic Stroke. ( Casas, S; De Nicola, AF; Folgueira, A; Gargiulo-Monachelli, GM; Gonzalez Deniselle, MC; Lopez, J; Mattiazzi, M; Perez, AF, 2017) |
| "Candesartan has been reported to have a protective effect on cerebral ischemia in vivo and in human ischemic stroke." | 3.81 | Candesartan improves ischemia-induced impairment of the blood-brain barrier in vitro. ( Deli, MA; Hayashi, K; Hiu, T; Matsuo, T; Morofuji, Y; Nagata, I; Nakagawa, S; Niwa, M; So, G; Suyama, K; Tanaka, K, 2015) |
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 3.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia." | 3.79 | Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013) |
| " Methylene blue exerted neuroprotective effects against the brain damage associated with the ischemia/reperfusion injury and ameliorated the blood-brain barrier disruption by decreasing nitric oxide metabolites." | 3.76 | Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions. ( Martijn, C; Miclescu, A; Sharma, HS; Wiklund, L, 2010) |
| "Daily intake of green tea catechins efficiently protects the penumbra from irreversible damage due to cerebral ischemia, and consequent neurologic deficits." | 3.72 | Protective effects of green tea catechins on cerebral ischemic damage. ( Ikeda, M; Suzuki, M; Tabuchi, M; Tomita, T; Umegaki, K, 2004) |
| "Treatment of Valsartan attenuated cerebral injury, potentiated the neuroprotective response of iPoCo in normal rats, and also restored the blunted neuroprotective effect of iPoCo in HFD-treated rats along with enhanced Nrf-2 levels." | 1.91 | Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury. ( Jaggi, AS; Kaur, S; Kumar, K; Singh, N, 2023) |
| "Valproic acid (VA) is an antiepileptic that is also used for the treatment of bipolar disorders." | 1.48 | Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions. ( Correia, AO; Costa, RO; da Silva Ribeiro, AE; de Barros Viana, GS; de Siqueira, KP; Dos Santos, GCA; Lima, DGS; Lucetti, DL; Lucetti, ECP; Moura, JA; Neves, KRT; Parente, LLT; Silva, MR, 2018) |
| " In this clinical study, we investigated whether PD-mediated impairment of nitric oxide (NO) bioavailability and signaling, in patients with persistently low systolic blood pressure (SBP), can explain the occurrence of cerebral ischemia." | 1.43 | Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia. ( Bárány, P; Békássy, Z; Cananau, C; Carlström, M; Checa, A; Hansson, S; Krmar, RT; Lundberg, JO; Sartz, L; Svensson, A; Weitzberg, E; Westphal, S; Wheelock, CE; Wide, K, 2016) |
| "Ischaemic stroke has become one of the leading causes of death and disability worldwide." | 1.43 | Suppression of ischaemia-induced injuries in rat brain by protease-activated receptor-1 (PAR-1) activating peptide. ( Lam, FFY; Ng, ESK; Zhen, X, 2016) |
| " The present study aims to determine the effect of short term (seven-days) administration of high dosage grape seed and skin extract (GSSE 2." | 1.42 | Protective effect of grape seed and skin extract on cerebral ischemia in rat: implication of transition metals. ( Ezzedine, A; Ferid, L; Meherzia, M; Mohamed, A; Mohamed, E; Pascal, C; Safwen, K; Selima, S, 2015) |
| "The neuronal damage following cerebral ischemia is a serious risk to stroke patients." | 1.37 | Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats. ( Ji, A; Liang, H; Liu, P; Song, S; Wang, Y, 2011) |
| "Increased duration of cerebral ischemia resulted in a progressive induction of oxidative stress." | 1.36 | MK-801 effect on regional cerebral oxidative stress rate induced by different duration of global ischemia in gerbils. ( Janac, B; Radenovic, L; Selakovic, V, 2010) |
| "Focal cerebral ischemia was induced in two sets of animals by permanent middle cerebral artery occlusion." | 1.35 | The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. ( Aral, E; Arslan, OC; Durmaz, R; Kanbak, G; Kartkaya, K; Ozden, H; Uzuner, K, 2008) |
| "We concluded that curcumin ameliorates cerebral ischemia/reperfusion injury by preventing ONOO(-) mediated blood-brain barrier damage." | 1.34 | Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. ( Hu, M; Jiang, J; Li, F; Sun, YJ; Wang, W; Zhu, DY, 2007) |
| "Focal cerebral ischemia in rats was produced by permanent occlusion of right middle cerebral artery (MCAO)." | 1.33 | Effects of MK-801 on nitrite and cGMP levels during focal cerebral ischemia in rats. ( Balkan, E; Balkan, S; Gümüslü, S; Ozben, T; Serteser, M, 2005) |
| "Forebrain ischemia was induced for 30 min by occlusion of the bilateral common carotid arteries without hemorrhagic hypotension." | 1.31 | Severe cerebral blood flow reduction inhibits nitric oxide synthesis. ( Fujisawa, H; Shima, H; Suzuki, M; Uetsuka, S; Yasuda, H, 2002) |
| "Melatonin treatment increased survival and reduced hyperactivity linked to neurodegeneration induced by cerebral ischemia and reperfusion." | 1.31 | Protective effects of melatonin in ischemic brain injury. ( Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I, 2000) |
| "Focal cerebral ischemia was produced by permanent occlusion of right MCA in urethane anesthetized rats." | 1.30 | The effects of nitric oxide synthase inhibitor, L-NAME on NO production during focal cerebral ischemia in rats: could L-NAME be the future treatment of sudden deafness? ( Balkan, E; Balkan, S; Gümüslü, S; Oguz, N; Ozben, T; Serteser, M, 1997) |
| "Compared to sham-operated controls, cerebral ischemia-reperfusion resulted in a significant increase in total and inducible NOS activity and a significant increase in the production of NO and superoxide in the cerebral hemispheres." | 1.30 | Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat. ( Forman, LJ; Liu, P; Nagele, RG; Wong, PY; Yin, K, 1998) |
| "Rats were subjected to global cerebral ischemia produced by occlusion of both common carotid arteries together with induced hypotension." | 1.29 | Brain nitrite production during global ischemia and reperfusion: an in vivo microdialysis study. ( Araki, N; Fukuuchi, Y; Hamada, J; Sasaki, T; Shibata, M; Shimazu, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (10.20) | 18.2507 |
| 2000's | 21 (42.86) | 29.6817 |
| 2010's | 21 (42.86) | 24.3611 |
| 2020's | 2 (4.08) | 2.80 |
| Authors | Studies |
|---|---|
| Kaur, S | 1 |
| Kumar, K | 1 |
| Singh, N | 1 |
| Jaggi, AS | 1 |
| Silver, JH | 1 |
| Jaffe, RA | 1 |
| López, JR | 1 |
| Casas, S | 1 |
| Perez, AF | 1 |
| Mattiazzi, M | 1 |
| Lopez, J | 1 |
| Folgueira, A | 1 |
| Gargiulo-Monachelli, GM | 1 |
| Gonzalez Deniselle, MC | 1 |
| De Nicola, AF | 1 |
| Silva, MR | 1 |
| Correia, AO | 1 |
| Dos Santos, GCA | 1 |
| Parente, LLT | 1 |
| de Siqueira, KP | 1 |
| Lima, DGS | 1 |
| Moura, JA | 1 |
| da Silva Ribeiro, AE | 1 |
| Costa, RO | 1 |
| Lucetti, DL | 1 |
| Lucetti, ECP | 1 |
| Neves, KRT | 1 |
| de Barros Viana, GS | 1 |
| Bhattacharya, P | 2 |
| Pandey, AK | 2 |
| Paul, S | 2 |
| Patnaik, R | 2 |
| Yavagal, DR | 1 |
| Safwen, K | 1 |
| Selima, S | 1 |
| Mohamed, E | 1 |
| Ferid, L | 1 |
| Pascal, C | 1 |
| Mohamed, A | 1 |
| Ezzedine, A | 1 |
| Meherzia, M | 1 |
| Gumanova, NG | 1 |
| Teplova, NV | 1 |
| Ryabchenko, AU | 1 |
| Denisov, EN | 1 |
| So, G | 1 |
| Nakagawa, S | 1 |
| Morofuji, Y | 1 |
| Hiu, T | 1 |
| Hayashi, K | 1 |
| Tanaka, K | 1 |
| Suyama, K | 1 |
| Deli, MA | 1 |
| Nagata, I | 1 |
| Matsuo, T | 1 |
| Niwa, M | 1 |
| Paspalj, D | 1 |
| Nikic, P | 1 |
| Savic, M | 1 |
| Djuric, D | 1 |
| Simanic, I | 1 |
| Zivkovic, V | 1 |
| Jeremic, N | 1 |
| Srejovic, I | 1 |
| Jakovljevic, V | 1 |
| Hess, DC | 1 |
| Hoda, MN | 1 |
| Khan, MB | 1 |
| Jin, YC | 1 |
| Lee, H | 1 |
| Kim, SW | 1 |
| Kim, ID | 1 |
| Lee, HK | 1 |
| Lee, Y | 1 |
| Han, PL | 1 |
| Lee, JK | 1 |
| Carlström, M | 1 |
| Cananau, C | 1 |
| Checa, A | 1 |
| Wide, K | 1 |
| Sartz, L | 1 |
| Svensson, A | 1 |
| Wheelock, CE | 1 |
| Westphal, S | 1 |
| Békássy, Z | 1 |
| Bárány, P | 1 |
| Lundberg, JO | 1 |
| Hansson, S | 1 |
| Weitzberg, E | 1 |
| Krmar, RT | 1 |
| Zhen, X | 1 |
| Ng, ESK | 1 |
| Lam, FFY | 1 |
| Kaur, J | 1 |
| Sharma, S | 2 |
| Sandhu, M | 1 |
| Fontes-Júnior, EA | 1 |
| Maia, CS | 1 |
| Fernandes, LM | 1 |
| Gomes-Leal, W | 1 |
| Costa-Malaquias, A | 1 |
| Lima, RR | 1 |
| Prediger, RD | 1 |
| Crespo-López, ME | 1 |
| Dohare, P | 1 |
| Garg, P | 1 |
| Jain, V | 1 |
| Nath, C | 1 |
| Ray, M | 1 |
| Moe, KT | 1 |
| Woon, FP | 1 |
| De Silva, DA | 1 |
| Wong, P | 1 |
| Koh, TH | 1 |
| Kingwell, B | 1 |
| Chin-Dusting, J | 1 |
| Wong, MC | 1 |
| Ito, Y | 1 |
| Ohkubo, T | 1 |
| Asano, Y | 1 |
| Hattori, K | 1 |
| Shimazu, T | 1 |
| Yamazato, M | 1 |
| Nagoya, H | 1 |
| Kato, Y | 1 |
| Araki, N | 2 |
| Selakovic, V | 2 |
| Janac, B | 1 |
| Radenovic, L | 2 |
| Yuan, Z | 1 |
| Liu, W | 1 |
| Liu, B | 1 |
| Schnell, A | 1 |
| Liu, KJ | 1 |
| Miclescu, A | 1 |
| Sharma, HS | 1 |
| Martijn, C | 1 |
| Wiklund, L | 1 |
| Jung, KH | 1 |
| Chu, K | 1 |
| Lee, ST | 1 |
| Sunwoo, JS | 1 |
| Park, DK | 1 |
| Kim, JH | 1 |
| Kim, S | 1 |
| Lee, SK | 1 |
| Kim, M | 1 |
| Roh, JK | 1 |
| Liang, H | 1 |
| Liu, P | 2 |
| Wang, Y | 1 |
| Song, S | 1 |
| Ji, A | 1 |
| Korenic, A | 1 |
| Ding-Zhou, L | 1 |
| Marchand-Verrecchia, C | 1 |
| Croci, N | 1 |
| Plotkine, M | 1 |
| Margaill, I | 1 |
| Uetsuka, S | 1 |
| Fujisawa, H | 1 |
| Yasuda, H | 1 |
| Shima, H | 1 |
| Suzuki, M | 2 |
| Temiz, C | 1 |
| Tun, K | 1 |
| Ugur, HC | 1 |
| Dempsey, RJ | 1 |
| Egemen, N | 1 |
| Hassan, A | 1 |
| Gormley, K | 1 |
| O'Sullivan, M | 1 |
| Knight, J | 1 |
| Sham, P | 1 |
| Vallance, P | 1 |
| Bamford, J | 1 |
| Markus, H | 1 |
| Maia, FD | 1 |
| Pitombeira, BS | 1 |
| Aráujo, DT | 1 |
| Cunha, GM | 2 |
| Viana, GS | 2 |
| Tabuchi, M | 1 |
| Ikeda, M | 1 |
| Umegaki, K | 1 |
| Tomita, T | 1 |
| Suk, K | 1 |
| Park, JH | 1 |
| Lee, WH | 1 |
| Galvão, RI | 1 |
| Diógenes, JP | 1 |
| Maia, GC | 1 |
| Filho, EA | 1 |
| Vasconcelos, SM | 1 |
| de Menezes, DB | 1 |
| Ozben, T | 2 |
| Balkan, E | 2 |
| Balkan, S | 2 |
| Serteser, M | 2 |
| Gümüslü, S | 2 |
| Hou, RC | 1 |
| Chen, YS | 1 |
| Chen, CH | 1 |
| Chen, YH | 1 |
| Jeng, KC | 1 |
| Xia, CF | 2 |
| Yin, H | 1 |
| Borlongan, CV | 2 |
| Chao, J | 2 |
| Chao, L | 2 |
| Smith, RS | 1 |
| Shen, B | 1 |
| Yang, ZR | 1 |
| Jiang, J | 1 |
| Wang, W | 1 |
| Sun, YJ | 1 |
| Hu, M | 1 |
| Li, F | 1 |
| Zhu, DY | 1 |
| Durmaz, R | 1 |
| Ozden, H | 1 |
| Kanbak, G | 1 |
| Aral, E | 1 |
| Arslan, OC | 1 |
| Kartkaya, K | 1 |
| Uzuner, K | 1 |
| Kumura, E | 2 |
| Kosaka, H | 2 |
| Shiga, T | 2 |
| Yoshimine, T | 2 |
| Hayakawa, T | 2 |
| Shibata, M | 1 |
| Hamada, J | 1 |
| Sasaki, T | 1 |
| Shimazu, K | 1 |
| Fukuuchi, Y | 1 |
| Takaoka, M | 1 |
| Oguz, N | 1 |
| Forman, LJ | 1 |
| Nagele, RG | 1 |
| Yin, K | 1 |
| Wong, PY | 1 |
| LeBlanc, MH | 1 |
| Feng, Y | 1 |
| Fratkin, JD | 1 |
| Calapai, G | 1 |
| Marciano, MC | 1 |
| Corica, F | 1 |
| Allegra, A | 1 |
| Parisi, A | 1 |
| Frisina, N | 1 |
| Caputi, AP | 2 |
| Buemi, M | 1 |
| Fassbender, K | 1 |
| Fatar, M | 1 |
| Ragoschke, A | 1 |
| Picard, M | 1 |
| Bertsch, T | 1 |
| Kuehl, S | 1 |
| Hennerici, M | 1 |
| Cuzzocrea, S | 1 |
| Costantino, G | 1 |
| Gitto, E | 1 |
| Mazzon, E | 1 |
| Fulia, F | 1 |
| Serraino, I | 1 |
| Cordaro, S | 1 |
| Barberi, I | 1 |
| De Sarro, A | 1 |
| Sakowitz, OW | 1 |
| Wolfrum, S | 1 |
| Sarrafzadeh, AS | 1 |
| Stover, JF | 1 |
| Dreier, JP | 1 |
| Dendorfer, A | 1 |
| Benndorf, G | 1 |
| Lanksch, WR | 1 |
| Unterberg, AW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Metabolism Research of KLK Treating Acute Cerebral Ischemic Stroke: Focus on Drug Frequency-Efficacy Relationship[NCT02806128] | 100 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
49 other studies available for nitrites and Cerebral Ischemia
| Article | Year |
|---|---|
Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain Ischemia; | 2023 |
Plasma nitrite as an indicator of cerebral ischemia during extracranial/intracranial bypass surgery in moyamoya patients.
Topics: Adult; Biomarkers; Brain Ischemia; Cerebral Revascularization; Cerebrovascular Circulation; Collater | 2020 |
Potential Biomarkers with Plasma Cortisol, Brain-derived Neurotrophic Factor and Nitrites in Patients with Acute Ischemic Stroke.
Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Brain-Derived Neurotrophic Factor; Female; Huma | 2017 |
Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Ischemia; Cyclooxygenase 2 Inhibitors; Dopamin | 2018 |
Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents.
Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Calcium; Dose-Response R | 2013 |
Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia.
Topics: Animals; Antioxidants; Apoptosis; Aquaporin 4; Blotting, Western; Brain Edema; Brain Ischemia; Calci | 2014 |
Protective effect of grape seed and skin extract on cerebral ischemia in rat: implication of transition metals.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Calcium; Calpain; Cerebral Infarction; Female; Malondi | 2015 |
Serum nitrate and nitrite levels in patients with hypertension and ischemic stroke depend on diet: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Diet; Female; Humans; Hypertension; Male; Middle Age | 2015 |
Candesartan improves ischemia-induced impairment of the blood-brain barrier in vitro.
Topics: Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain Ischemia; Cell Survival; Ele | 2015 |
Redox status in acute ischemic stroke: correlation with clinical outcome.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Catalase; Erythrocytes; Female; Humans; Hydrogen Peroxide; | 2015 |
Humoral Mediators of Remote Ischemic Conditioning: Important Role of eNOS/NO/Nitrite.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Chemokine CXCL12; Humans; Interleukin-10; Isch | 2016 |
Intranasal Delivery of RGD Motif-Containing Osteopontin Icosamer Confers Neuroprotection in the Postischemic Brain via αvβ3 Integrin Binding.
Topics: Administration, Intranasal; Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Brain; Brain Isc | 2016 |
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.
Topics: Arginine; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Female; Ho | 2016 |
Suppression of ischaemia-induced injuries in rat brain by protease-activated receptor-1 (PAR-1) activating peptide.
Topics: Amino Acid Sequence; Animals; Antioxidants; bcl-2-Associated X Protein; Brain; Brain Ischemia; Gene | 2016 |
Neurokinin-1 receptor inhibition reverses ischaemic brain injury and dementia in bilateral common carotid artery occluded rats: possible mechanisms.
Topics: Acetylcholinesterase; Animals; Aprepitant; Brain; Brain Ischemia; Carotid Stenosis; Dementia, Vascul | 2016 |
Chronic Alcohol Intoxication and Cortical Ischemia: Study of Their Comorbidity and the Protective Effects of Minocycline.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Brain Ischemia; Disease Models, Animal; Endotheli | 2016 |
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea | 2008 |
Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.
Topics: Acute Disease; Asian People; Brain Ischemia; DNA Mutational Analysis; Female; Gene Frequency; Geneti | 2008 |
Nitric oxide production during cerebral ischemia and reperfusion in eNOS- and nNOS-knockout mice.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pr | 2010 |
MK-801 effect on regional cerebral oxidative stress rate induced by different duration of global ischemia in gerbils.
Topics: Animals; Brain; Brain Ischemia; Carotid Artery, Common; Dizocilpine Maleate; Excitatory Amino Acid A | 2010 |
Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Hyperoxia; Ischemic Attack, Transient; Male; Middle Ce | 2010 |
Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Ischemia; Cardiopulmonary Resuscitation; Cere | 2010 |
Effects of long term nitrite therapy on functional recovery in experimental ischemia model.
Topics: Animals; Brain Ischemia; Caspases; Cytokines; Disease Models, Animal; Female; Humans; Neovasculariza | 2010 |
Protective effects of alkaloid extract from Leonurus heterophyllus on cerebral ischemia reperfusion injury by middle cerebral ischemic injury (MCAO) in rats.
Topics: Alkaloids; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Leonurus; Male; M | 2011 |
Spatial and temporal patterns of oxidative stress in the brain of gerbils submitted to different duration of global cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Gerbillinae; Glutathione; Lipid Peroxidation; Male; Nitric Oxide; Ni | 2011 |
L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Ischemia; Disease Models, Animal; Enzyme | 2002 |
Severe cerebral blood flow reduction inhibits nitric oxide synthesis.
Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Enzyme Inhibitors; In | 2002 |
L-arginine in focal cerebral ischemia.
Topics: Animals; Arginine; Brain Edema; Brain Ischemia; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitr | 2003 |
Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease.
Topics: Aged; Alleles; Brain; Brain Infarction; Brain Ischemia; Female; Gene Frequency; Genotype; Haplotypes | 2004 |
l-Deprenyl prevents lipid peroxidation and memory deficits produced by cerebral ischemia in rats.
Topics: Animals; Antioxidants; Avoidance Learning; Brain Ischemia; Disease Models, Animal; Dose-Response Rel | 2004 |
Protective effects of green tea catechins on cerebral ischemic damage.
Topics: Animals; Brain Ischemia; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, | 2004 |
Neuropeptide PACAP inhibits hypoxic activation of brain microglia: a protective mechanism against microglial neurotoxicity in ischemia.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain Ischemia; Cell Survival; Cells, Cultured; Cocult | 2004 |
Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Male; Neuroprotective Agents; Nitr | 2005 |
Effects of MK-801 on nitrite and cGMP levels during focal cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Male; Nitri | 2005 |
Protective effect of 1,2,4-benzenetriol on LPS-induced NO production by BV2 microglial cells.
Topics: Animals; Brain Ischemia; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hyd | 2006 |
Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis.
Topics: Adrenomedullin; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; B | 2006 |
Postischemic brain injury is exacerbated in mice lacking the kinin B2 receptor.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cerebral Infarction; Female; Glycogen Synthase Kinase 3; | 2006 |
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Capillaries; Curcuma; Curcumi | 2007 |
The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cerebral Cortex; Cysteine | 2008 |
Elevation of plasma nitric oxide end products during focal cerebral ischemia and reperfusion in the rat.
Topics: Animals; Arginine; Blood Pressure; Brain Ischemia; Drug Combinations; Male; NG-Nitroarginine Methyl | 1994 |
Brain nitrite production during global ischemia and reperfusion: an in vivo microdialysis study.
Topics: Animals; Brain; Brain Ischemia; Enzyme Inhibitors; Male; Microdialysis; NG-Nitroarginine Methyl Este | 1996 |
Hypothermia suppresses nitric oxide elevation during reperfusion after focal cerebral ischemia in rats.
Topics: Animals; Body Temperature; Brain Ischemia; Hemoglobins; Hypothermia, Induced; Jugular Veins; Male; N | 1996 |
The effects of nitric oxide synthase inhibitor, L-NAME on NO production during focal cerebral ischemia in rats: could L-NAME be the future treatment of sudden deafness?
Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebral Arteries; Cyclic GMP; Enzyme Inhibitors; Hearing | 1997 |
Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat.
Topics: Animals; Brain Ischemia; Enzyme Induction; Immunohistochemistry; Leukocyte Count; Male; Nitrates; Ni | 1998 |
N-tosyl-L-phenylalanyl-chloromethylketone reduces hypoxic-ischemic brain injury in rat pups.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; DNA; DNA Fragmentation; Dose-Response Relationship | 2000 |
Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation.
Topics: Aldehydes; Animals; Brain; Brain Edema; Brain Ischemia; Erythropoietin; Gerbillinae; Humans; Injecti | 2000 |
Subacute but not acute generation of nitric oxide in focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Corpus Striatum; Enzyme Inhibitors; Guanidines; Microdialysis; Nerve Degene | 2000 |
Protective effects of melatonin in ischemic brain injury.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scaveng | 2000 |
Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Fe | 2001 |