Page last updated: 2024-10-19

nitrites and Cardiovascular Stroke

nitrites has been researched along with Cardiovascular Stroke in 90 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"To assess the protective effects of lycopene on electrocardiographic, hemodynamic, biochemical and apoptotic changes in isoproterenol induced myocardial infarction."7.78Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study. ( Aman, U; Balaraman, R; Vaibhav, P, 2012)
"We examined the effects of chronic oral L-arginine treatment on endothelial and cardiovascular function in rats with heart failure induced by coronary artery ligation."7.70Effects of L-arginine on endothelial and cardiac function in rats with heart failure. ( Arnold, JM; Arnold, O; Feng, Q; Fortin, AJ; Lu, X, 1999)
"Treatment with hesperidin showed a significant increase in tissue nitrite, antioxidant level and reduction in inflammation, arrhythmias and apoptosis."5.35Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin. ( Balaraman, R; Gandhi, C; Upaganalawar, A, 2009)
" The inflammatory response expressed by PTX3 had a significant relationship with age, heart failure, infarct size, impaired flow in the infarct-related artery, and renal function and positively correlated with neopterin, TNF-α, 8-hydroxy-2'-deoxyguanosine, and nitrite/nitrate."3.81Prognostic value of pentraxin-3 level in patients with STEMI and its relationship with heart failure and markers of oxidative stress. ( Ganovska, E; Gottwaldova, J; Jarkovsky, J; Kala, P; Kubena, P; Kubkova, L; Littnerova, S; Mebazaa, A; Mueller, C; Parenica, J; Pavkova Goldbergova, M; Poloczek, M; Spinar, J; Tomandl, J; Tomandlova, M, 2015)
"To assess the protective effects of lycopene on electrocardiographic, hemodynamic, biochemical and apoptotic changes in isoproterenol induced myocardial infarction."3.78Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study. ( Aman, U; Balaraman, R; Vaibhav, P, 2012)
"This study was designed to evaluate the anti-inflammatory and anti-apoptotic effects of the alcoholic extract of the berries of Crataegus oxyacantha (AEC), a medicinal herb, on isoproterenol-induced myocardial infarction (MI) in a rat model."3.78Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage. ( Devaraj, SN; Thiruchenduran, M; Vijayan, NA, 2012)
"Inhibition of arginase protects from myocardial infarction by a mechanism that is dependent on NOS activity and bioavailability of NO by shifting arginine utilization from arginase towards NOS."3.76Arginase inhibition mediates cardioprotection during ischaemia-reperfusion. ( Gonon, AT; Jung, C; Lundberg, JO; Pernow, J; Sjöquist, PO, 2010)
"We examined the effects of chronic oral L-arginine treatment on endothelial and cardiovascular function in rats with heart failure induced by coronary artery ligation."3.70Effects of L-arginine on endothelial and cardiac function in rats with heart failure. ( Arnold, JM; Arnold, O; Feng, Q; Fortin, AJ; Lu, X, 1999)
" Under same haemodynamic conditions the treatment of angina pectoris consists of long acting nitrites in combination with a betablocking agent having some intrinsic activity."3.65[Ventricular aneurysm and coronary heart disease. Pathophysiology, differential therapy, and postoperative haemodynamics (author's transl)]. ( Bischoff, K; Johannes, E; Kugler, G, 1975)
" A decrease in the production and bioavailability of NO is a hallmark of many major chronic diseases including hypertension, ischaemia-reperfusion injury, atherosclerosis and diabetes."2.53Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases. ( Lundberg, JO; Omar, SA; Webb, AJ; Weitzberg, E, 2016)
"Hyperglycemia is known to inhibit ischemic and anesthetic preconditioning."1.36Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling. ( Gozal, Y; Navot, N; Raphael, J; Zuo, Z, 2010)
"Treatment with hesperidin showed a significant increase in tissue nitrite, antioxidant level and reduction in inflammation, arrhythmias and apoptosis."1.35Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin. ( Balaraman, R; Gandhi, C; Upaganalawar, A, 2009)
"Myocardial infarction was associated with lower whole blood nitrite levels (200+/-53 nmol/L for elevated serum CK MB levels vs 432+/-95 nmol/L in the normal CK MB range, p=0."1.35Serial measurements of whole blood nitrite in an intensive care setting. ( Balzer, J; Heusch, G; Kehmeier, ES; Kelm, M; Kleinbongard, P; Kropp, M; Lauer, T; Lepper, W; Merx, MW; Rassaf, T, 2008)
" Moreover, upregulation of NADH oxidase leads to increased presence of superoxide and peroxynitrite and thereby to a reduction of the bioavailability and compensatory effects of NO, as such influencing post-infarction remodelling."1.34Time-dependent expression pattern of nitric oxide and superoxide after myocardial infarction in rats. ( Berges, A; Timmermans, JP; Van Nassauw, L; Vrints, C, 2007)
" Long-term administration (2 mo) of the selective NOS II inhibitor S-methylisothiourea (SMT) to rats with MI significantly improved cardiac function."1.31Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure. ( Fahas, L; Giaid, A; Hu, F; Saito, T; Shennib, H; Tayara, L, 2002)
"Aspirin was administered intravenously (iv) as water-soluble Aspisol, d-lysinmono (acetylsalicylate) (Bayer, Leverkusen, Germany) into an ear vein."1.30Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin. ( Bing, RJ; Cho, YK; Cohen, AM; Johnson, PE; Kakar, NR; Yamamoto, M; Yamamoto, T, 1999)

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-199023 (25.56)18.7374
1990's5 (5.56)18.2507
2000's32 (35.56)29.6817
2010's29 (32.22)24.3611
2020's1 (1.11)2.80

Authors

AuthorsStudies
Koka, S1
Xi, L1
Kukreja, RC1
Gopcevic, K1
Rovcanin, B1
Kekic, D1
Milasinovic, D1
Kocic, G1
Stojanovic, I1
Totzeck, M2
Korste, S1
Miinalainen, I1
Hendgen-Cotta, UB3
Rassaf, T5
Vishwakarma, VK1
Goyal, A3
Gupta, JK2
Upadhyay, PK1
Yadav, HN3
Wang, Y1
Song, X1
Yue, X1
Su, H1
Gu, Y1
Bowman, L1
Ding, M1
Zou, B1
Zhao, J1
Lin, X1
Yellon, DM1
He, Z1
Khambata, R1
Ahluwalia, A1
Davidson, SM1
Sharma, AK1
Kumar, A1
Taneja, G1
Nagaich, U1
Deep, A1
Datusalia, AK1
Rajput, SK1
Naryzhnaya, NV3
Maslov, LN3
Tsibulnikov, SY2
Ma, H1
Lishmanov, YB2
Oeltgen, PR1
Garlid, K1
Inserte, J1
Hernando, V1
Vilardosa, Ú1
Abad, E1
Poncelas-Nozal, M1
Garcia-Dorado, D1
Sobierajski, J1
Kelm, M3
Aman, U1
Vaibhav, P1
Balaraman, R2
Qipshidze-Kelm, N1
Piell, KM1
Solinger, JC1
Cole, MP1
Tomandlova, M1
Jarkovsky, J1
Tomandl, J1
Kubkova, L1
Kala, P1
Littnerova, S1
Gottwaldova, J1
Kubena, P1
Ganovska, E1
Poloczek, M1
Spinar, J1
Mueller, C1
Mebazaa, A1
Pavkova Goldbergova, M1
Parenica, J1
Semwal, BC1
Omar, SA1
Webb, AJ1
Lundberg, JO2
Weitzberg, E1
Prokudina, ES1
Charan, K1
Valle Raleigh, J1
Mauro, AG1
Devarakonda, T1
Marchetti, C1
He, J1
Kim, E1
Filippone, S1
Das, A1
Toldo, S1
Abbate, A1
Salloum, FN1
Gonzalez, FM1
Shiva, S4
Vincent, PS1
Ringwood, LA1
Hsu, LY1
Hon, YY1
Aletras, AH1
Cannon, RO1
Gladwin, MT4
Arai, AE1
Merx, MW2
Schmitz, J1
Becher, S1
Klare, JP1
Steinhoff, HJ1
Goedecke, A1
Schrader, J1
Sinha, SS1
Caimi, G1
Montana, M1
Calandrino, V1
Caruso, M1
Carollo, C1
Catania, A1
Lo Presti, R1
Calvert, JW2
Lefer, DJ2
Tsikas, D1
Rossi, R1
Gandhi, C1
Upaganalawar, A1
Jung, C1
Gonon, AT1
Sjöquist, PO1
Pernow, J1
Milano, G1
Corno, AF1
Samaja, M1
Morel, S1
Vassalli, G1
von Segesser, LK1
Raphael, J1
Gozal, Y1
Navot, N1
Zuo, Z1
Joseph, PM1
Di Filippo, C1
Monopoli, A1
Ongini, E1
Perretti, M1
D'Amico, M1
Kudriashova, MV1
Dovgaliuk, IuV1
Mishina, LE1
Berezin, MV1
Grineva, MR1
Pakhrova, OA1
Mazanko, OE1
Akinmoladun, AC1
Obuotor, EM1
Barthwal, MK1
Dikshit, M1
Farombi, EO1
Wang, E1
Feng, Y1
Zhang, M1
Zou, L1
Li, Y1
Buys, ES1
Huang, P1
Brouckaert, P1
Chao, W1
Vijayan, NA1
Thiruchenduran, M1
Devaraj, SN1
Neye, N1
Enigk, F1
Habazettl, H1
Plesnila, N1
Kuppe, H1
Kuebler, WM1
Ikeda, U1
Maeda, Y1
Yamamoto, K1
Shimada, K1
Agata, J1
Chao, L2
Chao, J2
Wood, SP1
STREIT, M1
TAESCHLER, M1
MOMOT, MD1
FRAU, G1
BERGAMASCO, G1
SELJESKOG, EL1
HITCHCOCK, CR1
GROOVER, ME1
HAGLIN, JJ1
STROBEL, CJ1
WISING, PJ1
CHAND, A1
GAWELLEK, F1
ECKERT, H1
SOMERVILLE, W1
NORDQVIST, P1
VARNAUSKAS, E1
Ralay Ranaivo, H1
Diebolt, M1
Andriantsitohaina, R1
Berges, A2
Van Nassauw, L2
Timmermans, JP2
Vrints, C2
Zhu, YZ1
Chong, CL1
Chuah, SC1
Huang, SH1
Nai, HS1
Tong, HT1
Whiteman, M1
Moore, PK1
Jones, SP1
Bolli, R1
Drapkina, OM1
Ivashkin, VT1
Wajima, T1
Shimizu, S1
Hiroi, T1
Ishii, M1
Kiuchi, Y1
Kuralay, F1
Altekin, E1
Yazlar, AS1
Onvural, B1
Goldeli, O1
Baker, JE1
Su, J1
Fu, X1
Hsu, A1
Gross, GJ1
Tweddell, JS1
Hogg, N1
Yao, YY1
Yin, H1
Shen, B1
Bryan, NS1
Elrod, JW1
Gundewar, S1
Ji, SY1
Kehmeier, ES1
Kropp, M1
Kleinbongard, P1
Lauer, T1
Balzer, J1
Heusch, G1
Lepper, W1
Cía Gómez, P1
Akiyama, K2
Suzuki, H2
Grant, P1
Bing, RJ4
Kimura, A2
Takeyama, Y1
Gluckman, TL1
Terhakopian, A1
Katagiri, T1
Suh, KY2
Roseto, J2
Cohen, AM2
Yamamoto, T1
Kakar, NR1
Yamamoto, M1
Johnson, PE1
Cho, YK1
Feng, Q2
Fortin, AJ1
Lu, X2
Arnold, JM2
Arnold, O1
Giroux, M1
Ruidavets, JB1
Ferrières, J1
Manukhina, EB1
Smirin, BV2
Lyamina, NP1
Senchikhin, VN1
Vanin, AF1
Buikema, H1
Monnink, SH1
Tio, RA1
Crijns, HJ1
de Zeeuw, D1
van Gilst, WH1
Yoon, Y1
Song, J1
Hong, SH1
Kim, JQ1
Miyamoto, Y1
Saito, Y1
Nakayama, M1
Shimasaki, Y1
Yoshimura, T1
Yoshimura, M1
Harada, M1
Kajiyama, N1
Kishimoto, I1
Kuwahara, K1
Hino, J1
Ogawa, E1
Hamanaka, I1
Kamitani, S1
Takahashi, N1
Kawakami, R1
Kangawa, K1
Yasue, H1
Nakao, K1
Jain, AP1
Mohan, A1
Gupta, OP1
Jajoo, UN1
Kalantri, SP1
Srivastava, LM1
Hung, LM1
Chen, JK1
Lee, RS1
Liang, HC1
Su, MJ1
Jones, DL1
Shen, J1
Pshennikova, MG1
Belkina, LM1
Bakhtina, LY1
Baida, LA1
Malyshev, IY1
Saito, T1
Hu, F1
Tayara, L1
Fahas, L1
Shennib, H1
Giaid, A1
Erbel, R1
Belz, GG1
Johannes, E1
Bischoff, K1
Kugler, G1
Riecker, G1
Borghi, E1
Roventini, L1
Vecce, R1
Schembri, S1
Maurini, V1
Giomi, N1
Cantini, R1
Rindi, M1
Lenzi, R1
Barzi, F1
Dupuis, B1
Vincent, A1
Lablanche, JM1
França, A1
Nogueira Pereira, J1
Laires, MJ1
Pereira, T1
Rabaçal, C1
Halpern, MJ1
Simões Fernandes, J1
Duck, HJ1
Trenckmann, H1
Fleischmann, HJ1
Neugebauer, A1
Schauer, J1
Popescu, P1
Gherasim, L1
Lacher, JW1
Nager, F1
Monroe, RG1
Gamble, WJ1
LaFarge, CG1
Kumar, AE1
Stark, J1
Sanders, GL1
Phornphutkul, C1
Davis, M1
Likoff, W1
Ammermann, EO1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Safety and Efficacy Evaluation of Sodium Nitrite Injection for the Prevention of Ischemia-Reperfusion Injury Associated With Acute Myocardial Infarction.[NCT00924118]Phase 230 participants (Actual)Interventional2009-07-31Completed
Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular Dysfunction[NCT05711719]Phase 245 participants (Anticipated)Interventional2023-06-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Left Ventricular Infarct Size

Left ventricular infarct size by Magnetic Resonance Imaging (MRI). Calculated percentage of the left ventricular mass by MRI that has undergone infarction. (NCT00924118)
Timeframe: 4-5 days following enrollment

Interventioninfarct percentage of left ventricle (Mean)
Sodium Nitrite15.5
Open Control24

Reviews

9 reviews available for nitrites and Cardiovascular Stroke

ArticleYear
Nitrite-Nitric Oxide Signaling and Cardioprotection.
    Advances in experimental medicine and biology, 2017, Volume: 982

    Topics: Animals; Cytoprotection; Humans; Ischemic Preconditioning, Myocardial; Mitochondria, Heart; Myocardi

2017
[INVOLVEMENT OF NITRIC OXIDE CYNTHASE IN THE EARLY PHASE OF THE HEART ISCHEMIC PRECONDITIONING].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:7

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Isc

2016
[New strategies in cardioprotection during acute myocardial infarction: Impact of hypoxic nitrate-nitrite-NO signaling].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:15

    Topics: Animals; Humans; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; Nitra

2013
Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases.
    Journal of internal medicine, 2016, Volume: 279, Issue:4

    Topics: Animals; Biological Availability; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Di

2016
Myocardial protection by nitrite: evidence that this reperfusion therapeutic will not be lost in translation.
    Trends in cardiovascular medicine, 2008, Volume: 18, Issue:5

    Topics: Animals; Clinical Trials as Topic; Cytoprotection; Hemoglobins; Humans; Myocardial Infarction; Myoca

2008
Myocardial protection by nitrite.
    Cardiovascular research, 2009, Jul-15, Volume: 83, Issue:2

    Topics: Animals; Cytoprotection; Homeostasis; Humans; Myocardial Infarction; Myocardial Reperfusion Injury;

2009
The ubiquitous role of nitric oxide in cardioprotection.
    Journal of molecular and cellular cardiology, 2006, Volume: 40, Issue:1

    Topics: Animals; Heart; Humans; Ischemic Preconditioning, Myocardial; Mitochondria, Heart; Myocardial Infarc

2006
[Beta blockers in ischemic cardiopathy].
    Revista espanola de cardiologia, 1984, Volume: 37 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Dose-Response Relationship, Drug; Follow-Up S

1984
[Recent aspects on basic drug therapy of acute myocardial infarct].
    Medizinische Klinik, 1977, Sep-02, Volume: 72, Issue:35

    Topics: Adrenergic beta-Antagonists; Allopurinol; Analgesics; Anticoagulants; Aprotinin; Cardiac Glycosides;

1977

Other Studies

81 other studies available for nitrites and Cardiovascular Stroke

ArticleYear
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
    Molecular and cellular biochemistry, 2020, Volume: 468, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dyslipidemias; Heart; Insulin Resistance; Male;

2020
Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction.
    Folia biologica, 2017, Volume: 63, Issue:1

    Topics: Aged; Antioxidants; Case-Control Studies; Catalase; Gelatinases; Glutathione Peroxidase; Glutathione

2017
S-nitrosation of calpains is associated with cardioprotection in myocardial I/R injury.
    Nitric oxide : biology and chemistry, 2017, Jul-01, Volume: 67

    Topics: Animals; Calpain; Cell Line; Male; Mice, Inbred C57BL; Mitochondria; Myocardial Infarction; Myocardi

2017
Involvement of atrial natriuretic peptide in abrogated cardioprotective effect of ischemic preconditioning in ovariectomized rat heart.
    Human & experimental toxicology, 2018, Volume: 37, Issue:7

    Topics: Animals; Atrial Natriuretic Factor; Cardiotonic Agents; Creatine Kinase, MB Form; Female; Ischemic P

2018
Protection by nitrite against the ischemic effects induced by acute myocardial infarction in mice.
    Anatolian journal of cardiology, 2017, Volume: 18, Issue:5

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Disease Models, Animal; Male; Mice; Mice, Inbred

2017
The GTN patch: a simple and effective new approach to cardioprotection?
    Basic research in cardiology, 2018, 04-17, Volume: 113, Issue:3

    Topics: Administration, Cutaneous; Animals; Blood Pressure; Disease Models, Animal; Male; Mice, Inbred C57BL

2018
Combined and individual strategy of exercise generated preconditioning and low dose copper nanoparticles serve as superlative approach to ameliorate ISO-induced myocardial infarction in rats.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Androstadienes; Animals; Cardiotonic Agents; Copper; Creatine Kinase, MB Form; Glycogen Synthase Kin

2018
Role of protein kinase C, PI3 kinase, tyrosine kinases, NO-synthase, KATP channels and MPT pore in the signaling pathway of the cardioprotective effect of chronic continuous hypoxia.
    General physiology and biophysics, 2018, Volume: 37, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Cell Hypoxia; Hemodynamics; KATP Channels; Male; Mitochondrial Membra

2018
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
    Journal of the American Heart Association, 2013, Jan-02, Volume: 2, Issue:1

    Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, A

2013
Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study.
    Asian Pacific journal of tropical biomedicine, 2012, Volume: 2, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Carotenoids; Caspase 3; Disease Models, Animal

2012
Co-treatment with conjugated linoleic acid and nitrite protects against myocardial infarction.
    Redox biology, 2013, Volume: 2

    Topics: Animals; Dynamins; Echocardiography; Heart; Heme Oxygenase-1; Hemodynamics; Linoleic Acids, Conjugat

2013
Prognostic value of pentraxin-3 level in patients with STEMI and its relationship with heart failure and markers of oxidative stress.
    Disease markers, 2015, Volume: 2015

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Biomarkers; C-Reactive Protein; Deoxyguanosine; Female; Heart Fai

2015
Abrogated cardioprotective effect of ischemic preconditioning in ovariectomized rat heart.
    Human & experimental toxicology, 2016, Volume: 35, Issue:6

    Topics: Animals; Caveolin 1; Creatine Kinase, MB Form; Disease Models, Animal; Female; Heart; In Vitro Techn

2016
[INVOLVEMENT OF NO-SYNTHASE IN THE INFARCT REDUCING EFFECT OF CONTINUOUS CHRONIC NORMOBARTC HYPOXTA].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2015, Volume: 101, Issue:8

    Topics: Animals; Hypoxia; Ischemic Preconditioning, Myocardial; Isothiuronium; Male; Myocardial Infarction;

2015
Role of atrial natriuretic peptide in ischemic preconditioning-induced cardioprotection in the diabetic rat heart.
    The Journal of surgical research, 2016, Volume: 201, Issue:2

    Topics: Alloxan; Animals; Atrial Natriuretic Factor; Blood Glucose; Diabetes Mellitus, Experimental; Drug Ev

2016
Reperfusion therapy with recombinant human relaxin-2 (Serelaxin) attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury via eNOS-dependent mechanism.
    Cardiovascular research, 2017, May-01, Volume: 113, Issue:6

    Topics: Animals; Cardiovascular Agents; Caspase 1; Cells, Cultured; Disease Models, Animal; Inflammasomes; M

2017
Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction.
    Circulation, 2008, Jun-10, Volume: 117, Issue:23

    Topics: Animals; Anions; Apoptosis; Cardiotonic Agents; Cytoprotection; Disease Models, Animal; Dogs; Hemogl

2008
Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-22, Volume: 105, Issue:29

    Topics: Aconitate Hydratase; Animals; Cell Respiration; Cell Survival; Heme; In Vitro Techniques; Male; Mice

2008
Nitric oxide metabolites (nitrite and nitrate) in young patients with recent acute myocardial infarction.
    Clinical hemorheology and microcirculation, 2008, Volume: 40, Issue:2

    Topics: Adult; Female; Humans; Inflammation; Male; Myocardial Infarction; Nitrates; Nitric Oxide; Nitrites;

2008
Letter by Tsikas and Rossi regarding article, "Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction".
    Circulation, 2009, May-19, Volume: 119, Issue:19

    Topics: Animals; Apoptosis; Cardiotonic Agents; Combined Modality Therapy; Cytoprotection; Dogs; Erythrocyte

2009
Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin.
    Free radical research, 2009, Volume: 43, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arrhythmias, Car

2009
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.
    Cardiovascular research, 2010, Jan-01, Volume: 85, Issue:1

    Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Enzyme Inhibitors; Heart Rate; Male; Myoca

2010
Daily reoxygenation decreases myocardial injury and improves post-ischaemic recovery after chronic hypoxia.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2010, Volume: 37, Issue:4

    Topics: Animals; Body Weight; Chronic Disease; Hematocrit; Hemoglobins; Hypoxia; Male; Myocardial Infarction

2010
Hyperglycemia inhibits anesthetic-induced postconditioning in the rabbit heart via modulation of phosphatidylinositol-3-kinase/Akt and endothelial nitric oxide synthase signaling.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:4

    Topics: Anesthetics; Animals; Blood Glucose; Blood Pressure; Creatine Kinase, MB Form; Glucose; Heart; Heart

2010
Response to Bhaskaran et al's "Effects of air pollution on the incidence of myocardial infarction".
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:6

    Topics: Air Pollution; Humans; Myocardial Infarction; Nitrites; Ozone; Particulate Matter

2010
The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse.
    Microcirculation (New York, N.Y. : 1994), 2010, Volume: 17, Issue:6

    Topics: Animals; Cardiotonic Agents; Heme Oxygenase-1; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inh

2010
[Possibilities of correction of rheological properties of the blood and free radical processess in patients with acute myocardial infarction combined with type 2 diabetes mellitus].
    Kardiologiia, 2010, Volume: 50, Issue:5

    Topics: Arrhythmias, Cardiac; Blood Viscosity; Diabetes Mellitus, Type 2; Electrocardiography; Electrocardio

2010
Ramipril-like activity of Spondias mombin linn against no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:4

    Topics: Anacardiaceae; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Catalase; C

2010
Toll-like receptor 4 signaling confers cardiac protection against ischemic injury via inducible nitric oxide synthase- and soluble guanylate cyclase-dependent mechanisms.
    Anesthesiology, 2011, Volume: 114, Issue:3

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Echocardiography; Electrocardiography; Guanylate Cyc

2011
Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage.
    Molecular and cellular biochemistry, 2012, Volume: 367, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Catalase; Crataegus; Creatine Kinase; Cyclooxygenase 2

2012
Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function.
    Intensive care medicine, 2012, Volume: 38, Issue:8

    Topics: Administration, Inhalation; Animals; Cardiac Output; Cardiotonic Agents; Guanylate Cyclase; Male; Mo

2012
C-Reactive protein augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes.
    Cardiovascular research, 2002, Volume: 56, Issue:1

    Topics: Animals; C-Reactive Protein; Cardiomyopathy, Dilated; Cells, Cultured; Enzyme Inhibitors; Humans; In

2002
Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5

    Topics: Adenoviridae; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Dobutamine; Gene Transfer T

2002
Differentiating diagnoses.
    JEMS : a journal of emergency medical services, 2003, Volume: 28, Issue:1

    Topics: Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Chest Pain; Diagnosis, Dif

2003
[Pharmacodynamic studies on experimental cardiac infarcts in rats].
    Acta physiologica et pharmacologica Neerlandica, 1957, Volume: 6

    Topics: Animals; Electrocardiography; Myocardial Infarction; Nitrites; Papaverine; Rats

1957
[Characteristics of cardiovascular reactions to nitroglycerin in patients with myocardial infarct].
    "Laboratorio;" analisis clinicos, bacteriologia, inmunologia, parasitologia, hematologia, anatomia patologica, quimica clinica, 1960, Volume: 38

    Topics: Humans; Myocardial Infarction; Nitrites; Nitroglycerin

1960
[The use of intravenous nitroglycerin in the therapy of coronary disease. Preliminary results].
    Cardiologia, 1962, Volume: 40

    Topics: Administration, Intravenous; Angina Pectoris; Coronary Disease; Humans; Myocardial Infarction; Nitri

1962
Isosorbide dinitrate during acute coronary occlusion. Effects in the baboon.
    JAMA, 1963, Jan-19, Volume: 183

    Topics: Animals; Coronary Occlusion; Heart; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrites; P

1963
THE BECK-I OPERATION FOR ANGINA PECTORIS: MEDICAL ASPECTS.
    Acta medica Scandinavica, 1963, Volume: 174

    Topics: Angina Pectoris; Cardiac Surgical Procedures; Myocardial Infarction; Nitrites; Rehabilitation; Stati

1963
CORONARY ARTERY DISEASE AND MY DOUBTS.
    Journal of the Indian Medical Association, 1964, May-16, Volume: 42

    Topics: Anticoagulants; Arteriosclerosis; Cholesterol; Coronary Artery Disease; Coronary Disease; Dietary Fa

1964
[CATECHOLAMINE EXCRETION AND THE CLINICAL PICTURE IN THE MANAGEMENT OF CARDIAC INFARCTION AND CORONARY INSUFFICIENCY WITH N 3-PHENYLPROPYL -(2) 1, 1-DIPHENYL-PROPYL-(3)-AMINE].
    Das Deutsche Gesundheitswesen, 1964, Jul-16, Volume: 19

    Topics: Biphenyl Compounds; Catecholamines; Coronary Disease; Drug Therapy; Epinephrine; Geriatrics; Infarct

1964
The diagnosis and man agement of coronary disease.
    Archives. Middlesex Hospital, 1955, Volume: 5, Issue:2

    Topics: Angina Pectoris; Anticoagulants; Coronary Disease; Humans; Myocardial Infarction; Nitrites

1955
[Ettriol trinitrate--a new nitrate compound].
    Svenska lakartidningen, 1960, Jul-22, Volume: 57

    Topics: Angina Pectoris; Myocardial Infarction; Nitrates; Nitrites; Nitrogen Oxides

1960
Wine polyphenols induce hypotension, and decrease cardiac reactivity and infarct size in rats: involvement of nitric oxide.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Administration, Oral; Aldehydes; Animals; Blood Pressure; Blotting, Western; Carbachol; Coronary Cir

2004
Role of nitric oxide during coronary endothelial dysfunction after myocardial infarction.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: Adenosine; Amidines; Animals; Benzylamines; Bradykinin; Coronary Circulation; Cytochrome P-450 Enzym

2005
Cardioprotective effects of nitroparacetamol and paracetamol in acute phase of myocardial infarction in experimental rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:2

    Topics: Acetaminophen; Animals; Capillaries; Cardiotonic Agents; Coronary Vessels; Hemodynamics; Liver; Male

2006
[Nitric oxide and cardiac failure].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:11

    Topics: Adult; Cardiac Output, Low; Case-Control Studies; Female; Humans; Leukocytes, Mononuclear; Male; Mid

2005
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Rel

2006
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidine.
    The Tohoku journal of experimental medicine, 2006, Volume: 208, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Huma

2006
Time-dependent expression pattern of nitric oxide and superoxide after myocardial infarction in rats.
    Pharmacological research, 2007, Volume: 55, Issue:1

    Topics: Animals; Enzyme Activation; Immunohistochemistry; Kinetics; Male; Myocardial Infarction; Myocardium;

2007
Nitrite confers protection against myocardial infarction: role of xanthine oxidoreductase, NADPH oxidase and K(ATP) channels.
    Journal of molecular and cellular cardiology, 2007, Volume: 43, Issue:4

    Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; KATP Channels; Male; Myocardial Infar

2007
Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction.
    Journal of cardiac failure, 2007, Volume: 13, Issue:7

    Topics: Animals; Capillaries; Cardiac Output, Low; Cardiomegaly; Cells, Cultured; Collagen; Coronary Vessels

2007
Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Administration, Oral; Animals; Dietary Supplements; Drug Evaluation, Preclinical; Heme; Mice; Myocar

2007
Serial measurements of whole blood nitrite in an intensive care setting.
    Free radical biology & medicine, 2008, Jun-01, Volume: 44, Issue:11

    Topics: Aged; Creatine Kinase, MB Form; Critical Illness; Female; Humans; Intensive Care Units; Kidney Funct

2008
Oxidation products of nitric oxide, NO2 and NO3, in plasma after experimental myocardial infarction.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:1

    Topics: Analysis of Variance; Animals; Enzyme Induction; Hemodynamics; Linear Models; Male; Myocardial Infar

1997
Production of oxidative products of nitric oxide in infarcted human heart.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Arteries; Coronary Angiography; Coronary Vessels; Diastole; Female; Follow-

1998
Effect of acetylsalicylic acid on nitric oxide production in infarcted heart in situ.
    Biochemical and biophysical research communications, 1998, Oct-29, Volume: 251, Issue:3

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Heart; Injections, In

1998
Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin.
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Vessels; Enzyme Activation; Epoprostenol; H

1999
Effects of L-arginine on endothelial and cardiac function in rats with heart failure.
    European journal of pharmacology, 1999, Jul-02, Volume: 376, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Heart; Heart Failure; Hemodynamics; Male;

1999
Atmospheric NO, temperature and ischaemic heart disease. Study in Toulouse and its conurbation.
    The Science of the total environment, 2000, Feb-10, Volume: 246, Issue:2-3

    Topics: Air; Ammonia; France; Humans; Humidity; Myocardial Infarction; Myocardial Ischemia; Nitric Oxide; Ni

2000
Role of nitric oxide in adaptation to hypoxia and adaptive defense.
    Physiological research, 2000, Volume: 49, Issue:1

    Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Hypo

2000
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; B

2000
Plasma nitric oxide concentrations and nitric oxide synthase gene polymorphisms in coronary artery disease.
    Clinical chemistry, 2000, Volume: 46, Issue:10

    Topics: Aged; Coronary Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitric O

2000
Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T-->C mutation associated with coronary spastic angina.
    Human molecular genetics, 2000, Nov-01, Volume: 9, Issue:18

    Topics: Alleles; Amino Acid Sequence; Angina Pectoris; Animals; Base Sequence; Cell Line; DNA-Binding Protei

2000
Role of oxygen free radicals in causing endothelial damage in acute myocardial infarction.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:5

    Topics: Adult; Aged; Coronary Artery Disease; Endothelium, Vascular; Female; Free Radicals; Humans; India; M

2000
Beneficial effects of astringinin, a resveratrol analogue, on the ischemia and reperfusion damage in rat heart.
    Free radical biology & medicine, 2001, Apr-15, Volume: 30, Issue:8

    Topics: Animals; Antioxidants; Free Radical Scavengers; Heart; Hemodynamics; L-Lactate Dehydrogenase; Male;

2001
Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice.
    Circulation, 2001, Aug-07, Volume: 104, Issue:6

    Topics: Animals; Female; Gene Expression Regulation, Enzymologic; Genotype; Heart Ventricles; Hemodynamics;

2001
HSP70 stress proteins, nitric oxide, and resistance of August and Wistar rats to myocardial infarction.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:2

    Topics: Animals; Genetic Predisposition to Disease; HSP70 Heat-Shock Proteins; Male; Myocardial Infarction;

2001
Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Animals; Blotting, Western; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Failu

2002
[Ventricular aneurysm and coronary heart disease. Pathophysiology, differential therapy, and postoperative haemodynamics (author's transl)].
    Medizinische Klinik, 1975, Oct-17, Volume: 70, Issue:42

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Coronary Disease; Digitalis Glycosides; D

1975
[Coronary disease. Introduction].
    Der Internist, 1977, Volume: 18, Issue:6

    Topics: Angiography; Coronary Angiography; Coronary Disease; Creatine Kinase; Glucose; Humans; Insulin; Myoc

1977
[Prolonged use of intravenous nitro derivatives in acute myocardial infarction (AMI)].
    Minerva cardioangiologica, 1989, Volume: 37, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Electrocardiography; Female; Humans; Injections, Intravenous; Male;

1989
[Evaluation of anti-ischemia treatment in man].
    Archives des maladies du coeur et des vaisseaux, 1987, Volume: 80 Spec No

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Agents; Coronary Disease; Drug

1987
Serum magnesium levels in patients after myocardial infarction or unstable angina treated with nitrites and calcium antagonists.
    Magnesium, 1985, Volume: 4, Issue:5-6

    Topics: Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Drug Therapy, Combination; Follow-Up St

1985
[Drug therapy of ischemic heart disease in ambulatory practice].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Nov-15, Volume: 29, Issue:22

    Topics: Adrenergic beta-Antagonists; Ambulatory Care; Analgesics; Angina Pectoris; Anticoagulants; Coronary

1974
[Current problems in diagnosis and treatment of angina pectoris].
    Medicina interna, 1972, Volume: 24, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angiography; Anticoagulants; Benzofurans; Coronary Ang

1972
Acquired methemoglobinemia. A case report.
    Rocky Mountain medical journal, 1973, Volume: 70, Issue:6

    Topics: Aged; Cyanosis; Food Additives; Humans; Male; Methemoglobinemia; Myocardial Infarction; Nitrites

1973
[Conservative therapy of angina pectoris].
    Schweizerische medizinische Wochenschrift, 1970, May-16, Volume: 100, Issue:20

    Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides

1970
The Anrep effect reconsidered.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:10

    Topics: Adenosine Triphosphate; Aminophylline; Animals; Blood Flow Velocity; Blood Pressure; Catheterization

1972
Coronary heart disease. New aspects of prevention and treatment.
    The Journal of the Medical Society of New Jersey, 1970, Volume: 67, Issue:8

    Topics: Adult; Angina Pectoris; Angiography; Animals; Coronary Disease; Digitalis Glycosides; Dogs; Electroc

1970
A contribution to treatment of angina pectoris with a long acting nitrate (dilcoran 80).
    Die Medizinische Welt, 1967, Jun-17, Volume: 24

    Topics: Angina Pectoris; Humans; Myocardial Infarction; Nitrites

1967