Page last updated: 2024-10-19

nitrites and Cardiovascular Diseases

nitrites has been researched along with Cardiovascular Diseases in 119 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0."7.96The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020)
"Patients with essential hypertension (n = 24) were administered a low-salt diet (2 g NaCl/day), a high-salt diet (20-23 g) and then a low-salt diet for 7 days, and plasma levels of nitrate and nitrite (NOx) and asymmetric dimethylarginine (ADMA) were examined."5.10Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease. ( Fujiwara, N; Nakamura, M; Okumura, K; Osanai, T; Osawa, H; Saitoh, M; Sasaki, S; Tomita, H; Yamabe, H, 2002)
"Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0."3.96The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020)
"Aging is associated with a vasoconstrictive, pro-coagulant, and pro-inflammatory profile of arteries and a decline in the bioavailability of the endothelium-derived molecule nitric oxide."2.84Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study. ( Allen, JD; Briskey, D; Fassett, R; Hickey, D; Kerr, G; Leveritt, M; Neubauer, O; Ortiz de Zevallos Munoz, J; Parker, TJ; Peake, JM; Pecheniuk, NM; Raubenheimer, K, 2017)
"Dementia is a significant public health priority with approximately 55 million cases worldwide, and this number is predicted to quadruple by 2050."2.82Dietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention? ( Alharbi, M; Babateen, A; Shannon, O; Siervo, M; Stephan, B, 2022)
" We investigated the role of nitric oxide (NO) bioavailability in mediating these effects."2.78Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man. ( Barath, S; Blackwell, S; Blomberg, A; Bosson, J; Langrish, JP; Megson, IL; Mills, NL; Muala, A; Newby, DE; Pourazar, J; Sandström, T; Söderberg, S; Treweeke, A; Unosson, J, 2013)
" Our primary objective was to investigate the dose-response of nitrate intake on nitric oxide status and nitrate reduction in the mouth."2.77Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women. ( Bondonno, CP; Considine, MJ; Croft, KD; Hodgson, JM; Puddey, IB; Ward, NC; Yang, X, 2012)
" A decrease in the production and bioavailability of NO is a hallmark of many major chronic diseases including hypertension, ischaemia-reperfusion injury, atherosclerosis and diabetes."2.53Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases. ( Lundberg, JO; Omar, SA; Webb, AJ; Weitzberg, E, 2016)
" Dysfunction in the production and/or the bioavailability of NO characterizes endothelial dysfunction, which is associated with cardiovascular diseases such as hypertension and atherosclerosis."2.52Vascular nitric oxide: Beyond eNOS. ( Leung, SW; Vanhoutte, PM; Zhao, Y, 2015)
" Inorganic nitrite is a promising precursor molecule for augmenting circulating and tissue NO bioavailability because it requires only a one-step reduction to NO."2.50Inorganic nitrite supplementation for healthy arterial aging. ( Devan, AE; Fleenor, BS; Seals, DR; Sindler, AL, 2014)
" Impaired bioavailability of nitric oxide (NO), which is a critical regulator of vascular homeostasis, in the vasculature is thought to be a major problem in cardiovascular disease."2.48Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables? ( Machha, A; Schechter, AN, 2012)
" A role for nitrite and nitrate in nitric oxide biosynthesis and/or in improving nitric oxide bioavailability may eventually provide a rationale for using dietary nitrite and nitrate supplementation in the treatment and prevention of cardiovascular diseases."2.47Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits. ( Machha, A; Schechter, AN, 2011)
"The weak and inconclusive data on the cancer risk of nitrite, nitrate and processed meats are far outweighed by the health benefits of restoring NO homeostasis via dietary nitrite and nitrate."2.46Nutritional epidemiology in the context of nitric oxide biology: a risk-benefit evaluation for dietary nitrite and nitrate. ( Bryan, NS; Coughlin, JR; Garg, HK; Milkowski, A, 2010)
"To compare the circulating levels of adiponectin and nitric oxide (NO) bioavailability in eutrophic, eutrophic hypertensive, obese, and obese hypertensive children and adolescents, and to assess whether adiponectin is associated with increased NO bioavailability in these children and adolescents."1.39Adiponectin associates positively with nitrite levels in children and adolescents. ( Belo, VA; Carmo, VP; Lacchini, R; Lanna, CM; Sertório, JT; Souza-Costa, DC; Tanus-Santos, JE, 2013)
" Chronic and persistent depletion of plasma and salivary nitrite and nitrate probably reduces NO bioavailability and may explain in part the increased cardiovascular mortality in the dialysis patient."1.39Acute effects of hemodialysis on nitrite and nitrate: potential cardiovascular implications in dialysis patients. ( Berkson, DL; Bryan, NS; Mian, AI; Moncrief, JW; Torregrossa, AC; Westby, CM, 2013)
"Panic disorder (PD) and major depressive disorders (MDD) are serious mental disorders but the mechanisms underlying the pathophysiology are poorly understood."1.38Biological understanding of the cardiovascular risk associated with major depression and panic disorder is important. ( Aydogan, S; Ozüm, Ü; Yapislar, H, 2012)
" In conclusion, our study suggests that chronic administration of celecoxib may have a damaging effect on kidney, as evident through altered histopathology and renal functions."1.34Role of oxidative stress in celecoxib-induced renal damage in wistar rats. ( Aggarwal, R; Agnihotri, N; Dutta, N; Gupta, S; Sarotra, P, 2007)
" Plasma RXNOs may be diagnostically useful markers of NO bioavailability and a surrogate index of endothelial function."1.33Plasma nitroso compounds are decreased in patients with endothelial dysfunction. ( Dejam, A; Feelisch, M; Hamada, S; Heiss, C; Kelm, M; Kleinbongard, P; Lauer, T; Matern, S; Rassaf, T, 2006)

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-199011 (9.24)18.7374
1990's7 (5.88)18.2507
2000's27 (22.69)29.6817
2010's63 (52.94)24.3611
2020's11 (9.24)2.80

Authors

AuthorsStudies
Kotopoulou, S1
Zampelas, A1
Magriplis, E1
Morou-Bermúdez, E1
Torres-Colón, JE1
Bermúdez, NS1
Patel, RP1
Joshipura, KJ1
Goh, CE2
Bohn, B2
Marotz, C1
Molinsky, R1
Roy, S1
Paster, BJ1
Chen, CY1
Rosenbaum, M1
Yuzefpolskaya, M1
Colombo, PC1
Desvarieux, M1
Papapanou, PN1
Jacobs, DR1
Knight, R1
Demmer, RT2
Liddle, L1
Monaghan, C1
Burleigh, MC1
Baczynska, KA1
Muggeridge, DJ1
Easton, C1
Lundberg, JO6
Weitzberg, E3
Srour, B1
Chazelas, E1
Fezeu, LK1
Javaux, G1
Pierre, F1
Huybrechts, I1
Hercberg, S1
Deschasaux-Tanguy, M1
Kesse-Guyot, E1
Touvier, M1
Siervo, M1
Babateen, A1
Alharbi, M1
Stephan, B1
Shannon, O1
Bryan, NS9
Ahmed, S1
Lefer, DJ5
Hord, N2
von Schwarz, ER1
Moretti, C1
Zhuge, Z1
Zhang, G2
Haworth, SM1
Paulo, LL1
Guimarães, DD1
Cruz, JC1
Montenegro, MF1
Cordero-Herrera, I1
Braga, VA1
Carlström, M1
Mayyas, FA1
Aljohmani, AI1
Alzoubi, KH1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y4
Wang, J6
Huang, L2
Hu, K1
Liu, H4
Wang, H3
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Wang, W2
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X4
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J4
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J2
Jiang, H2
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X4
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z3
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Zhang, X6
Xu, N1
Wang, R1
Liu, S1
He, H1
Dong, X2
Yang, M2
Yang, Q1
Duan, S1
Yu, Y2
Han, J2
Zhang, C3
Chen, L2
Yang, X3
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H4
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Yang, S1
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S1
Zhai, X1
Wang, C2
Gilson, E1
Ye, J1
Lu, Y1
Yan, R1
Zhang, Y7
Hu, Z1
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Zhao, X1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Wang, Y7
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L5
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X1
Huang, X2
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M2
An, Z1
Jiang, J2
Li, J7
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Liu, Y7
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A1
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L1
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X3
Wu, Y2
Zhang, H1
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Fan, Y2
Sun, YB1
Wang, AL1
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J2
Chu, S1
Pan, Q1
Li, D2
Zheng, S2
Ma, L1
Wang, L3
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X1
Dai, T1
Yang, Y3
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
Li, Y4
Du, Q1
Hao, P1
Cao, X1
Li, CX1
Zhao, S1
Luo, XM1
Feng, JX1
Gonzalez-Cotto, M1
Guo, L1
Karwan, M1
Sen, SK1
Barb, J1
Collado, CJ1
Elloumi, F1
Palmieri, EM1
Boelte, K1
Kolodgie, FD1
Finn, AV1
Biesecker, LG1
McVicar, DW1
Qu, F1
Deng, Z1
Xie, Y2
Tang, J3
Chen, Z2
Luo, W1
Xiong, D1
Zhao, D1
Fang, J1
Zhou, Z1
Niu, PP1
Song, B1
Xu, YM1
Zhang, Z2
Qiu, N1
Yin, J1
Zhang, J3
Guo, W1
Liu, M2
Liu, T2
Chen, D5
Luo, K1
He, Z2
Zheng, G1
Xu, F1
Sun, W1
Yin, F1
van Hest, JCM1
Du, L2
Shi, X1
Kang, S1
Duan, W1
Zhang, S2
Feng, J2
Qi, N1
Shen, G1
Ren, H1
Shang, Q1
Zhao, W2
Yang, Z2
Jiang, X2
Alame, M1
Cornillot, E1
Cacheux, V1
Tosato, G1
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De Oliveira, L1
Gofflot, S1
Delvenne, P1
Turtoi, E1
Cabello-Aguilar, S1
Nishiyama, M1
Turtoi, A1
Costes-Martineau, V1
Colinge, J1
Guo, Q1
Quan, M1
Dong, J1
Bai, J1
Han, R1
Cai, Y1
Lv, YQ1
Chen, Q1
Lyu, HD1
Deng, L1
Zhou, D1
Xiao, X1
De Langhe, S1
Billadeau, DD1
Lou, Z1
Zhang, JS1
Xue, Z1
Shen, XD1
Gao, F1
Busuttil, RW1
Kupiec-Weglinski, JW1
Ji, H1
Otano, I1
Alvarez, M1
Minute, L1
Ochoa, MC1
Migueliz, I1
Molina, C1
Azpilikueta, A1
de Andrea, CE1
Etxeberria, I1
Sanmamed, MF1
Teijeira, Á1
Berraondo, P1
Melero, I1
Zhong, Z1
Xie, X1
Yu, Q1
Zhou, C1
Liu, C2
Liu, W1
Chen, W1
Yin, Y1
Li, CW1
Hsu, JL1
Zhou, Q1
Hu, B1
Fu, P1
Atyah, M1
Ma, Q2
Xu, Y1
Dong, Q1
Hung, MC1
Ren, N1
Huang, P1
Liao, R1
Chen, X3
Cao, Q1
Yuan, X1
Nie, W1
Yang, J2
Shao, B1
Ma, X1
Bi, Z1
Liang, X1
Tie, Y1
Mo, F1
Xie, D1
Wei, Y1
Wei, X2
Dokla, EME1
Fang, CS1
Chu, PC1
Chang, CS1
Abouzid, KAM1
Chen, CS1
Blaszczyk, R1
Brzezinska, J1
Dymek, B1
Stanczak, PS1
Mazurkiewicz, M1
Olczak, J1
Nowicka, J1
Dzwonek, K1
Zagozdzon, A1
Golab, J1
Golebiowski, A1
Xin, Z1
Himmelbauer, MK1
Jones, JH1
Enyedy, I1
Gilfillan, R1
Hesson, T1
King, K1
Marcotte, DJ1
Murugan, P1
Santoro, JC1
Gonzalez-Lopez de Turiso, F1
Pedron, J1
Boudot, C1
Brossas, JY1
Pinault, E1
Bourgeade-Delmas, S1
Sournia-Saquet, A1
Boutet-Robinet, E1
Destere, A1
Tronnet, A1
Bergé, J1
Bonduelle, C1
Deraeve, C1
Pratviel, G1
Stigliani, JL1
Paris, L1
Mazier, D1
Corvaisier, S1
Since, M1
Malzert-Fréon, A1
Wyllie, S1
Milne, R1
Fairlamb, AH1
Valentin, A1
Courtioux, B1
Verhaeghe, P1
Fang, X1
Gao, M1
Gao, H1
Bi, W1
Tang, H1
Cui, Y1
Zhang, L3
Fan, H1
Yu, H1
Mathison, CJN1
Chianelli, D1
Rucker, PV1
Nelson, J1
Roland, J1
Huang, Z2
Xie, YF1
Epple, R1
Bursulaya, B1
Lee, C1
Gao, MY1
Shaffer, J1
Briones, S1
Sarkisova, Y1
Galkin, A1
Li, N1
Li, C2
Hua, S1
Kasibhatla, S1
Kinyamu-Akunda, J1
Kikkawa, R1
Molteni, V1
Tellew, JE1
Jin, X1
Pang, B1
Liu, Q2
Liu, X3
Huang, Y2
Josephine Fauci, A1
Ma, Y1
Soo Lee, M1
Yuan, W1
Gao, R1
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Duchêne-Marullaz, P1
Lavarenne, J1
McDermott, JH1
Kabler, PW1
Wolf, HW1
Poletti, RA1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Testing the Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function in Older Adults Living With Overweight or Obesity: A 28-Day Pilot Randomised Trial[NCT06151015]20 participants (Anticipated)Interventional2024-01-01Not yet recruiting
Effects of Dietary Nitrate on Vascular Function, Blood Pressure, the Oral Microbiome, and Biomarkers of Systemic Inflammation in Hypertensive Older Adults: a Randomized, Placebo-controlled Crossover Study[NCT04584372]20 participants (Actual)Interventional2021-01-01Completed
The Cardiovascular Effects of Air Pollution: the Role of Nitric Oxide[NCT00845767]16 participants (Anticipated)Interventional2009-04-30Completed
Diesel Exhaust Inhalation, Systemic Nitric Oxide Inhibition and Cardiac Output[NCT01060930]14 participants (Actual)Interventional2010-03-31Completed
Dietary Nitrate on Salivary Flow for Nasopharyngeal Carcinoma Patients Pre and Post Concurrent Chemo-radiation Therapy[NCT02854410]30 participants (Anticipated)Interventional2016-08-31Not yet recruiting
Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With Unexplained Recurrent Pregnancy Loss[NCT05341856]Early Phase 160 participants (Anticipated)Interventional2022-05-01Not yet recruiting
Impact of Acute Exercise on Vascular Insulin Sensitivity in Metabolic Syndrome[NCT03894527]16 participants (Anticipated)Interventional2019-02-18Recruiting
'Oral Microbiome -Dietary Nitrate' Interactions and Cognitive Health in Older Age[NCT05518214]60 participants (Anticipated)Interventional2021-09-29Recruiting
Investigation of the Sex Differences in Oral Microbiota and Their Effect on Circulating Nitrite Levels[NCT01583803]24 participants (Anticipated)Observational2012-06-30Active, not recruiting
The Acute Effect of Beetroot Juice on Circulating Nitrate and Nitrite Levels and Blood Pressure in Normotensives and Hypertensives[NCT01236872]15 participants (Actual)Interventional2009-12-31Completed
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Meat Intake - Pilot Study of the Nitrate INFORMER Studies; Nitrate INFORMER Studies: Is Nitrosamine FORMation dEpenent on souRce[NCT05045807]6 participants (Actual)Interventional2021-10-11Completed
Randomised Controlled Trial to Investigate N-nitrosamine Formation After Meat Intake - Meat Study of the Nitrate INFORMER Studies; Nitrate INFORMER Studies: Is Nitrosamine FORMation dEpenent on souRce[NCT05075720]25 participants (Actual)Interventional2022-09-27Completed
Examination of the Distribution of Nitrate Reducing Bacteria in the Human Oral Cavity[NCT03068962]20 participants (Anticipated)Interventional2017-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

31 reviews available for nitrites and Cardiovascular Diseases

ArticleYear
Dietary nitrate and nitrite and human health: a narrative review by intake source.
    Nutrition reviews, 2022, 03-10, Volume: 80, Issue:4

    Topics: Animals; Cardiovascular Diseases; Diet; Humans; Neoplasms; Nitrates; Nitrites

2022
Nitric oxide signaling in health and disease.
    Cell, 2022, 08-04, Volume: 185, Issue:16

    Topics: Animals; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Humans; Mammals; Nitric Ox

2022
Dietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention?
    The British journal of nutrition, 2022, 09-28, Volume: 128, Issue:6

    Topics: Brain; Cardiovascular Diseases; Dementia; Diet; Humans; Nitrates; Nitric Oxide; Nitrites

2022
Dietary nitrate biochemistry and physiology. An update on clinical benefits and mechanisms of action.
    Nitric oxide : biology and chemistry, 2023, 03-01, Volume: 132

    Topics: Cardiovascular Diseases; Humans; Inflammation; Nitrates; Nitric Oxide; Nitrites

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
The role of inorganic nitrate and nitrite in CVD.
    Nutrition research reviews, 2017, Volume: 30, Issue:2

    Topics: Aged; Animals; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Diet; Fruit; Huma

2017
Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen.
    Pharmacological research, 2017, Volume: 122

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Diet; Humans; Nitrates; Nitric Oxide; Nitrites; Ni

2017
The role of inorganic nitrate and nitrite in cardiovascular disease risk factors: a systematic review and meta-analysis of human evidence.
    Nutrition reviews, 2018, 05-01, Volume: 76, Issue:5

    Topics: Adult; Aged; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Diet; Female; Humans; M

2018
Functional Nitric Oxide Nutrition to Combat Cardiovascular Disease.
    Current atherosclerosis reports, 2018, 03-17, Volume: 20, Issue:5

    Topics: Blood Pressure; Cardiovascular Diseases; Female; Humans; Male; Microbiota; Nitrates; Nitric Oxide; N

2018
Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Nutrients, 2018, Dec-20, Volume: 11, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Dietary Supplements; Endothelium,

2018
Inorganic nitrite supplementation for healthy arterial aging.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-01, Volume: 116, Issue:5

    Topics: Aging; Animals; Arteries; Cardiotonic Agents; Cardiovascular Diseases; Dietary Supplements; Endothel

2014
Inorganic nitrite and nitrate: evidence to support consideration as dietary nutrients.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:8

    Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Consumer Product Safety; Diet; Disease Mode

2015
A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer?
    Molecular nutrition & food research, 2016, Volume: 60, Issue:1

    Topics: Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Diet, Vegetarian; Fruit; Humans; Nit

2016
Vascular nitric oxide: Beyond eNOS.
    Journal of pharmacological sciences, 2015, Volume: 129, Issue:2

    Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, V

2015
Vascular nitric oxide: Beyond eNOS.
    Journal of pharmacological sciences, 2015, Volume: 129, Issue:2

    Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, V

2015
Vascular nitric oxide: Beyond eNOS.
    Journal of pharmacological sciences, 2015, Volume: 129, Issue:2

    Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, V

2015
Vascular nitric oxide: Beyond eNOS.
    Journal of pharmacological sciences, 2015, Volume: 129, Issue:2

    Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, V

2015
Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases.
    Journal of internal medicine, 2016, Volume: 279, Issue:4

    Topics: Animals; Biological Availability; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Di

2016
It is rocket science - why dietary nitrate is hard to 'beet'! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:1

    Topics: Animals; Cardiovascular Diseases; Diet, Mediterranean; Humans; Nitrates; Nitric Oxide; Nitrites

2017
Microbiota and the nitrogen cycle: Implications in the development and progression of CVD and CKD.
    Nitric oxide : biology and chemistry, 2016, 07-01, Volume: 57

    Topics: Ammonia; Animals; Cardiovascular Diseases; Disease Progression; Dysbiosis; Humans; Microbiota; Nitra

2016
Special Lecture.
    Nihon saikingaku zasshi. Japanese journal of bacteriology, 2017, Volume: 72, Issue:1

    Topics: Bacteria; Cardiovascular Diseases; Colorectal Neoplasms; Cytokines; Humans; Inflammasomes; Inflammat

2017
Emerging role of nitrite in myocardial protection.
    Archives of pharmacal research, 2009, Volume: 32, Issue:8

    Topics: Animals; Cardiovascular Diseases; Cytoprotection; Homeostasis; Humans; Myocardial Reperfusion Injury

2009
Nutritional epidemiology in the context of nitric oxide biology: a risk-benefit evaluation for dietary nitrite and nitrate.
    Nitric oxide : biology and chemistry, 2010, Feb-15, Volume: 22, Issue:2

    Topics: Animals; Cardiovascular Diseases; Diet; Humans; Neoplasms; Nitrates; Nitric Oxide; Nitrites; Nutriti

2010
Clinical translation of nitrite therapy for cardiovascular diseases.
    Nitric oxide : biology and chemistry, 2010, Feb-15, Volume: 22, Issue:2

    Topics: Animals; Cardiovascular Diseases; Humans; Nitrites; Translational Research, Biomedical

2010
The emerging role of nitrite as an endogenous modulator and therapeutic agent of cardiovascular function.
    Current medicinal chemistry, 2010, Volume: 17, Issue:18

    Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Humans; Nitric Oxide; N

2010
Nitrite as a physiological source of nitric oxide and a signalling molecule in the regulation of the cardiovascular system in both mammalian and non-mammalian vertebrates.
    Recent patents on cardiovascular drug discovery, 2010, Volume: 5, Issue:2

    Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Homeostasis; Humans; Mammals; Nitric Oxide;

2010
Cardioprotective effects of nitrite during exercise.
    Cardiovascular research, 2011, Feb-15, Volume: 89, Issue:3

    Topics: Cardiotonic Agents; Cardiovascular Diseases; Exercise; Humans; Nitric Oxide; Nitrites; Risk Factors

2011
Nitrite and nitrate: cardiovascular risk-benefit and metabolic effect.
    Current opinion in lipidology, 2011, Volume: 22, Issue:1

    Topics: Cardiovascular Diseases; Humans; Nitrates; Nitrites

2011
Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits.
    European journal of nutrition, 2011, Volume: 50, Issue:5

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Diet; Dietary Supplements; Endothelium; H

2011
Dietary nitrates, nitrites, and cardiovascular disease.
    Current atherosclerosis reports, 2011, Volume: 13, Issue:6

    Topics: Cardiovascular Diseases; Diet; Fertilizers; Humans; Nitrates; Nitrites; Skin; Soil Pollutants; Veget

2011
Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables?
    Nutrition reviews, 2012, Volume: 70, Issue:6

    Topics: Biological Availability; Cardiovascular Diseases; Humans; Nitrates; Nitric Oxide; Nitrites; Nutritio

2012
Nitric oxide: an ancestral immunocyte effector molecule.
    Advances in neuroimmunology, 1995, Volume: 5, Issue:4

    Topics: Animals; Cardiovascular Diseases; Cell Adhesion; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzy

1995
Dietary nitrate in man: friend or foe?
    The British journal of nutrition, 1999, Volume: 81, Issue:5

    Topics: Bacteria; Bacterial Infections; Cardiovascular Diseases; Diet; Humans; Intestines; Methemoglobinemia

1999
[Recent data on coronary dilators].
    Actualites pharmacologiques, 1968, Volume: 21

    Topics: Amino Alcohols; Aminophylline; Animals; Benzofurans; Cardiovascular Diseases; Cats; Coronary Disease

1968

Trials

19 trials available for nitrites and Cardiovascular Diseases

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Flavonoid-Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease: A Randomized Controlled Clinical Trial.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:3

    Topics: Aged; Blood Pressure; Cardiotonic Agents; Cardiovascular Diseases; Cholesterol, LDL; Endothelium, Va

2018
Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study.
    Nutrients, 2017, Nov-22, Volume: 9, Issue:11

    Topics: Aged; Aging; Beta vulgaris; Biomarkers; Blood Platelets; Blood Pressure; Cardiovascular Diseases; CD

2017
Effect of Acute Dietary Nitrate Supplementation on the Post-Exercise Ambulatory Blood Pressure in Obese Males: A Randomized, Controlled, Crossover Trial.
    Journal of sports science & medicine, 2019, Volume: 18, Issue:1

    Topics: Adult; Anthropometry; Beta vulgaris; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Di

2019
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
    Journal of the American Heart Association, 2013, Feb-19, Volume: 2, Issue:1

    Topics: Adult; Air Pollutants; Arginine; Biological Availability; Blood Pressure; Cardiac Output; Cardiovasc

2013
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
    Journal of the American Heart Association, 2013, Feb-19, Volume: 2, Issue:1

    Topics: Adult; Air Pollutants; Arginine; Biological Availability; Blood Pressure; Cardiac Output; Cardiovasc

2013
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
    Journal of the American Heart Association, 2013, Feb-19, Volume: 2, Issue:1

    Topics: Adult; Air Pollutants; Arginine; Biological Availability; Blood Pressure; Cardiac Output; Cardiovasc

2013
Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.
    Journal of the American Heart Association, 2013, Feb-19, Volume: 2, Issue:1

    Topics: Adult; Air Pollutants; Arginine; Biological Availability; Blood Pressure; Cardiac Output; Cardiovasc

2013
Effects of a dietary strawberry powder on parameters of vascular health in adolescent males.
    The British journal of nutrition, 2016, Volume: 116, Issue:4

    Topics: Adolescent; Beverages; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Diet; Double-Blind M

2016
High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans.
    Vascular medicine (London, England), 2016, Volume: 21, Issue:5

    Topics: Administration, Oral; Adult; Beverages; Biomarkers; Brachial Artery; Cardiovascular Diseases; Coconu

2016
Combined exercise reduces arterial stiffness, blood pressure, and blood markers for cardiovascular risk in postmenopausal women with hypertension.
    Menopause (New York, N.Y.), 2017, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Biomarkers; Blood Pressure; Body Composition; Cardiov

2017
Effect of exercise intensity on postprandial lipemia, markers of oxidative stress, and endothelial function after a high-fat meal.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:12

    Topics: Biomarkers; Brazil; Cardiovascular Diseases; Diet, High-Fat; Endothelium, Vascular; Exercise; Exerci

2016
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:2

    Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli

2010
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:2

    Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli

2010
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:2

    Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli

2010
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:2

    Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli

2010
Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: a randomized controlled trial.
    Free radical biology & medicine, 2012, Jan-01, Volume: 52, Issue:1

    Topics: Adult; Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Endothelium, Va

2012
Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women.
    Food & function, 2012, Volume: 3, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Female; Human

2012
Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women.
    Food & function, 2012, Volume: 3, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Female; Human

2012
Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women.
    Food & function, 2012, Volume: 3, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Female; Human

2012
Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women.
    Food & function, 2012, Volume: 3, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Female; Human

2012
Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Aged; Beta vulgaris; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dietary Sup

2013
Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease.
    Blood purification, 2002, Volume: 20, Issue:5

    Topics: Arginine; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Failure, Chr

2002
Effect of supplemental phytonutrients on impairment of the flow-mediated brachial artery vasoactivity after a single high-fat meal.
    Journal of the American College of Cardiology, 2003, May-21, Volume: 41, Issue:10

    Topics: Adult; Antioxidants; Brachial Artery; Cardiovascular Diseases; Cholesterol; Dietary Fats; Dietary Su

2003
Comparative vascular effects of hormone replacement therapy and raloxifene in women at increased cardiovascular risk.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 18, Issue:6

    Topics: Aged; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Endothelin-

2004
Different effect of hormone replacement therapy, DHEAS and tibolone on endothelial function in postmenopausal women with increased cardiovascular risk.
    Maturitas, 2005, Apr-11, Volume: 50, Issue:4

    Topics: Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind M

2005
Plasma nitrate plus nitrite changes during continuous intravenous infusion interleukin 2.
    British journal of cancer, 1996, Volume: 74, Issue:8

    Topics: Adult; Aged; Carcinoma, Renal Cell; Cardiovascular Diseases; Drug Administration Schedule; Female; H

1996
A comparison of the effects of two continuous HRT regimens on cardiovascular risk factors.
    Atherosclerosis, 2002, Volume: 160, Issue:1

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; E

2002

Other Studies

70 other studies available for nitrites and Cardiovascular Diseases

ArticleYear
Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health.
    Journal of dental research, 2022, Volume: 101, Issue:6

    Topics: Ammonium Compounds; Bacteria; Cardiovascular Diseases; Humans; Microbiota; Nitrates; Nitric Oxide; N

2022
Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS.
    Journal of the American Heart Association, 2022, 05-17, Volume: 11, Issue:10

    Topics: Adult; Bacteria; Cardiovascular Diseases; Female; Humans; Male; Microbiota; Nitrates; Nitric Oxide;

2022
Reduced nitric oxide synthesis in winter: A potential contributing factor to increased cardiovascular risk.
    Nitric oxide : biology and chemistry, 2022, 10-01, Volume: 127

    Topics: Adult; Cardiovascular Diseases; Female; Heart Disease Risk Factors; Humans; Nitric Oxide; Nitrites;

2022
Nitrites, Nitrates, and Cardiovascular Outcomes: Are We Living "La Vie en Rose" With Pink Processed Meats?
    Journal of the American Heart Association, 2022, 12-20, Volume: 11, Issue:24

    Topics: Adult; Cardiovascular Diseases; Diet; Food Additives; Humans; Hypertension; Meat; Nitrates; Nitrites

2022
The obligatory role of host microbiota in bioactivation of dietary nitrate.
    Free radical biology & medicine, 2019, Volume: 145

    Topics: Animals; Blood Pressure; Body Weight; Cardiovascular Diseases; Cardiovascular System; Diet, Western;

2019
The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats.
    Current molecular pharmacology, 2020, Volume: 13, Issue:3

    Topics: Aldosterone; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Cardiovascular Diseases

2020
The impact of glucose exposure on bioenergetics and function in a cultured endothelial cell model and the implications for cardiovascular health in diabetes.
    Scientific reports, 2020, 11-11, Volume: 10, Issue:1

    Topics: Cardiovascular Diseases; Cell Death; Cell Line; Diabetes Mellitus; Endothelial Cells; Endothelium, V

2020
Assessing the Relationship Between Nitrate-Reducing Capacity of the Oral Microbiome and Systemic Outcomes.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2327

    Topics: Cardiovascular Diseases; Humans; Microbiota; Mouth; Nitrates; Nitric Oxide; Nitrites; RNA, Ribosomal

2021
Association of Ozone Exposure With Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults.
    JAMA internal medicine, 2017, 09-01, Volume: 177, Issue:9

    Topics: Adult; Air Pollution; Breath Tests; Cardiovascular Diseases; China; Environmental Exposure; Female;

2017
Inorganic Nitrate: Marker or Mediator of Mortality?
    Journal of the American Heart Association, 2017, 11-18, Volume: 6, Issue:11

    Topics: Cardiovascular Diseases; Humans; Incidence; Nitrates; Nitrites; Nitrogen Oxides

2017
Experience of correcting endothelial dysfunction in children-residents of radioactively contaminated areas by nitric oxide potential donator citrulline.
    Problemy radiatsiinoi medytsyny ta radiobiolohii, 2017, Volume: 22

    Topics: Arginine; Bronchial Spasm; Cardiovascular Diseases; Chernobyl Nuclear Accident; Child; Citrulline; E

2017
Millettia macrophylla (Fabaceae) phenolic fraction prevents differentiation of 3T3-L1 adipocytes and the increased risks of cardiovascular diseases in ovariectomized rats.
    Journal of ethnopharmacology, 2018, Aug-10, Volume: 222

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Aorta; Cardiovascular Diseases; Catalase; Cell Differentiation; C

2018
Optimization of Single-Step Assay for Circulating Nitrite and Nitrate Ions (NOx) as Risk Factors of Cardiovascular Mortality.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:2

    Topics: Biomarkers; Blood Chemical Analysis; Blood Proteins; Calibration; Cardiovascular Diseases; Chemical

2018
Increased Plasma Nitrite and von Willebrand Factor Indicates Early Diagnosis of Vascular Diseases in Chemotherapy Treated Cancer Patients.
    Cardiovascular toxicology, 2019, Volume: 19, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Biomarkers; Cardiotoxicity; Cardiovascular Diseases; Ca

2019
Elevated levels of serum nitrite and nitrate, NOx, are associated with increased total and cardiovascular mortality in an 8-year follow-up study.
    European journal of clinical investigation, 2019, Volume: 49, Issue:3

    Topics: Aged; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middl

2019
Dietary nitrates and nitrites-harmful? Helpful? Or paradox?
    Journal of the Academy of Nutrition and Dietetics, 2013, Volume: 113, Issue:9

    Topics: Animals; Carcinogens; Cardiovascular Diseases; Diet; Food Preservation; Humans; Infant; Meat; Methem

2013
Nitric oxide metabolites (nitrite and nitrate) in several clinical condition.
    Clinical hemorheology and microcirculation, 2014, Volume: 56, Issue:4

    Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Diabetes Mellitus; Female; Humans; Hypertensio

2014
Stress alone or associated with ethanol induces prostanoid release in rat aorta via alpha2-Adrenoceptor.
    Arquivos brasileiros de cardiologia, 2014, Volume: 102, Issue:3

    Topics: Alcohol Drinking; Animals; Aorta, Thoracic; Cardiovascular Diseases; Endothelium, Vascular; Ethanol;

2014
The potential use of salivary nitrite as a marker of NO status in humans.
    Nitric oxide : biology and chemistry, 2015, Feb-15, Volume: 45

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Metabolic Networks and Pathways; Nitric Oxide; Nitrites

2015
Genetic Effects of eNOS Polymorphisms on Biomarkers Related to Cardiovascular Status in a Population Coexposed to Methylmercury and Lead.
    Archives of environmental contamination and toxicology, 2015, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Brazil; Cardiovascular Disea

2015
It is rocket science - why dietary nitrate is hard to 'beet'! Part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:1

    Topics: Cardiovascular Diseases; Diet, Mediterranean; Humans; Life Style; Nitrates; Nitric Oxide; Nitrites

2017
Added value of total serum nitrate/nitrite for prediction of cardiovascular disease in middle east caucasian residents in Tehran.
    Nitric oxide : biology and chemistry, 2016, Apr-01, Volume: 54

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Female; Humans; Iran; Middle Ag

2016
Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop.
    Journal of the American Heart Association, 2016, 07-06, Volume: 5, Issue:7

    Topics: Cardiovascular Diseases; Diet; Heart; Humans; National Heart, Lung, and Blood Institute (U.S.); Nitr

2016
Serum nitrite and nitrate levels, NOx, can predict cardiovascular mortality in the elderly in a 3-year follow-up study.
    BioFactors (Oxford, England), 2017, Jan-02, Volume: 43, Issue:1

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Male; Middle Ag

2017
Cardiovascular prevention by dietary nitrate and nitrite.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Diseases; Diet; Endothelium, Vascular; Humans; Hyp

2009
Nitric oxide bioactivity of traditional Chinese medicines used for cardiovascular indications.
    Free radical biology & medicine, 2009, Sep-15, Volume: 47, Issue:6

    Topics: Animals; Aorta, Thoracic; Cardiovascular Diseases; Drugs, Chinese Herbal; Magnoliopsida; Male; Medic

2009
Is sunlight good for our heart?
    European heart journal, 2010, Volume: 31, Issue:9

    Topics: Cardiovascular Diseases; Environmental Exposure; Heart; Humans; Nitric Oxide; Nitrites; Phototherapy

2010
Review focus on inorganic nitrite and nitrate in cardiovascular health and disease.
    Cardiovascular research, 2011, Feb-15, Volume: 89, Issue:3

    Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Humans; Nitrates; Nitrites

2011
Plasma nitrate levels and flow-mediated vasodilation in untreated major depression.
    Psychosomatic medicine, 2011, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Case-Control Studi

2011
Determination of the effects of eNOS gene polymorphisms (T-786C and Glu298Asp) on nitric oxide levels in a methylmercury-exposed population.
    Journal of toxicology and environmental health. Part A, 2011, Volume: 74, Issue:20

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiovascular Diseases; Female; Glutamic Acid; Humans; Male

2011
Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Antioxidants; Cardiovascular Diseases

2011
Biological understanding of the cardiovascular risk associated with major depression and panic disorder is important.
    International journal of psychiatry in clinical practice, 2012, Volume: 16, Issue:1

    Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Depressi

2012
Intron 4 polymorphism of the endothelial nitric oxide synthase (eNOS) gene is associated with decreased NO production in a mercury-exposed population.
    The Science of the total environment, 2012, Jan-01, Volume: 414

    Topics: Age Factors; Animals; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Female; Fishes; Gene

2012
Effects of lipoprotein-associated phospholipase A2 on arginase/nitric oxide pathway in hemodialysis patients.
    Renal failure, 2012, Volume: 34, Issue:6

    Topics: Arginase; Biomarkers; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Stu

2012
Adiponectin associates positively with nitrite levels in children and adolescents.
    International journal of obesity (2005), 2013, Volume: 37, Issue:5

    Topics: Adiponectin; Adolescent; Analysis of Variance; Biological Availability; Biomarkers; Body Mass Index;

2013
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:3

    Topics: Beta vulgaris; Blood Pressure; Blood Vessels; Cardiovascular Diseases; Cardiovascular System; Diet;

2013
Acute effects of hemodialysis on nitrite and nitrate: potential cardiovascular implications in dialysis patients.
    Free radical biology & medicine, 2013, Volume: 58

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Free Radicals; Humans; Male; Middle

2013
An increase in urinary nitrite/nitrate excretion is associated with the hyperdynamic state after cardiovascular surgery.
    Intensive care medicine, 2002, Volume: 28, Issue:8

    Topics: Aged; Aged, 80 and over; Cardiopulmonary Bypass; Cardiovascular Agents; Cardiovascular Diseases; Chr

2002
Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation.
    Journal of toxicology and environmental health. Part A, 2002, Oct-25, Volume: 65, Issue:20

    Topics: Air Pollutants; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Cardiovascular Diseases

2002
Concomitant presence of N-nitroso and S-nitroso proteins in human plasma.
    Free radical biology & medicine, 2002, Dec-01, Volume: 33, Issue:11

    Topics: Adult; Albumins; Cardiovascular Diseases; Female; Free Radicals; Humans; Male; Mercury; Middle Aged;

2002
Cyclooxygenase-2 inhibition attenuates lipopolysaccharide-induced cardiovascular failure.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2002
[Therapy of peripheral circulatory disorders with tetraethylammonium nitrite].
    Acta neurovegetativa, 1953, Volume: 8, Issue:1

    Topics: Cardiovascular Diseases; Nitrites; Peripheral Vascular Diseases; Tetraethylammonium; Vascular Diseas

1953
[The treatment of cardiovascular diseases].
    Medizinische Klinik, 1955, Oct-21, Volume: 50, Issue:42

    Topics: Anti-Arrhythmia Agents; Cardiovascular Diseases; Coronary Disease; Diuretics; Humans; Nitrites

1955
[Short wave diathermy and nitrite therapy].
    Therapie der Gegenwart, 1955, Volume: 94, Issue:11

    Topics: Cardiovascular Diseases; Diathermy; Humans; Hyperthermia, Induced; Nitrates; Nitrites; Pain Manageme

1955
[Findings and comments on the value of some semeiotico-instrumental tests for diagnosis of cardiovascular complications in diabetics].
    Minerva medica, 1958, Jan-06, Volume: 49, Issue:1-2

    Topics: Ballistocardiography; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Electrocar

1958
The role of venous constriction in circulatory disorders.
    British heart journal, 1958, Volume: 20, Issue:3

    Topics: Cardiovascular Diseases; Constriction; Constriction, Pathologic; Heart Failure; Nitrites; Vascular D

1958
Use of a PETN-ataractic combination (cartrax) in the long term management of the cardiovascular geriatric patient.
    The Journal of the Florida Medical Association. Florida Medical Association, 1960, Volume: 47

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cardiovascular System; Disease Management; Hydroxy

1960
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
    Circulation, 2004, Feb-03, Volume: 109, Issue:4

    Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Cells, Cultured; Coronary Angiography; Coronary

2004
[Effect of sodium nitrite in acute cardiac insufficiency].
    Magyar belorvosi archivum es ideggyogyaszati szemle, 1951, Volume: 4, Issue:2

    Topics: Cardiovascular Diseases; Heart; Heart Failure; Humans; Nitrites; Sodium Nitrite

1951
A study of the therapeutic action and toxicity of pentaerythritol tetranitrate.
    Angiology, 1952, Volume: 3, Issue:1

    Topics: Cardiovascular Diseases; Nitrites; Pentaerythritol Tetranitrate

1952
Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.
    Blood, 2004, Oct-01, Volume: 104, Issue:7

    Topics: Cardiovascular Diseases; Cell Differentiation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; E

2004
Endothelial nitric oxide synthase polymorphism, nitric oxide production, salt sensitivity and cardiovascular risk factors in Hispanics.
    Journal of human hypertension, 2005, Volume: 19, Issue:3

    Topics: Adult; Alleles; Blood Pressure; Cardiovascular Diseases; DNA; Female; Genetic Markers; Genotype; His

2005
Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans.
    Free radical biology & medicine, 2006, Jan-15, Volume: 40, Issue:2

    Topics: Adult; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male

2006
Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake.
    Free radical biology & medicine, 2006, Feb-01, Volume: 40, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blotting, Western; Cardiovascular Diseases; Case-Control Studies

2006
Plasma nitroso compounds are decreased in patients with endothelial dysfunction.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Endoth

2006
Nitric oxide metabolites and cardiovascular disease markers, mediators, or both?
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Nitrites; Nitroso

2006
17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide synthase and GTP cyclohydrolase I by high glucose: relevance to postmenopausal diabetic cardiovascular disease.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: Animals; Biopterins; Cardiovascular Diseases; Cattle; Cells, Cultured; Diabetes Complications; Down-

2007
Role of oxidative stress in celecoxib-induced renal damage in wistar rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:11

    Topics: Animals; Biomarkers; Cardiovascular Diseases; Catalase; Celecoxib; Creatinine; Cyclooxygenase Inhibi

2007
Therapeutic uses of inorganic nitrite and nitrate: from the past to the future.
    Circulation, 2008, Apr-22, Volume: 117, Issue:16

    Topics: Cardiovascular Diseases; History, 15th Century; History, 16th Century; History, 17th Century; Histor

2008
Role of nitric oxide in a nonseptic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:5

    Topics: Acute Disease; Animals; Ascitic Fluid; Blood Pressure; Cardiovascular Diseases; Enzyme Inhibitors; M

1997
Prevalence of positive urinary dipstick analysis (leucocyte esterase, nitrite, haemoglobin, or glucose) in a population of 3645 adult subjects--consequence for measurement of urinary albumin excretion rate.
    Scandinavian journal of urology and nephrology, 1998, Volume: 32, Issue:6

    Topics: Adult; Aged; Albuminuria; Carboxylic Ester Hydrolases; Cardiovascular Diseases; Cross-Sectional Stud

1998
Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:5

    Topics: Animals; Blood Circulation; Cardiovascular Diseases; Glutathione; Hemodynamics; Lipid Peroxides; Liv

1999
Pentoxifylline improves circulatory failure and survival in murine models of endotoxaemia.
    European journal of pharmacology, 1999, May-28, Volume: 373, Issue:1

    Topics: Anesthesia; Animals; Aorta, Thoracic; Blood Circulation; Blood Pressure; Cardiovascular Diseases; Di

1999
[Influence of the presence of hot flashes during menopause on the metabolism of nitric oxide. Effects of hormonal replacement treatment].
    Medicina clinica, 2000, Jan-22, Volume: 114, Issue:2

    Topics: Adult; Analysis of Variance; Antioxidants; Bilirubin; Blood Glucose; Cardiovascular Diseases; Choles

2000
[Hot flashes, menopause, nitric oxide and hormone replacement therapy: "one for all and all for one"].
    Medicina clinica, 2000, Jan-22, Volume: 114, Issue:2

    Topics: Adult; Animals; Antioxidants; Cardiovascular Diseases; Estradiol; Estrogen Replacement Therapy; Estr

2000
Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury.
    Thrombosis and haemostasis, 2000, Volume: 84, Issue:1

    Topics: Adult; Arm; Arteriosclerosis; Calcium; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL;

2000
Alteration in plasma antioxidant capacities in chronic renal failure and hemodialysis patients: a possible explanation for the increased cardiovascular risk in these patients.
    Cardiovascular research, 2000, Aug-18, Volume: 47, Issue:3

    Topics: Aged; Analysis of Variance; Antioxidants; Ascorbic Acid; Cardiovascular Diseases; Case-Control Studi

2000
Possible role of nitric oxide and mast cells in endotoxin-induced cardioprotection.
    Pharmacological research, 2001, Volume: 43, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Canavanine; Cardiovascular Diseases; Cell

2001
Health aspects of toxic materials in drinking water.
    American journal of public health, 1971, Volume: 61, Issue:11

    Topics: Arsenic Poisoning; Attitude to Health; Cardiovascular Diseases; Communicable Disease Control; Englan

1971
[Nitrite therapy].
    Prensa medica argentina, 1971, Volume: 58, Issue:23

    Topics: Adult; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Male; M

1971