nitrites has been researched along with Brain Swelling in 16 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 7.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia." | 7.79 | Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013) |
| "Melatonin at 60 min post ischemia rendered neuroprotection as evident by reduction in cerebral infarct volume, improvement in motor and neurological deficit and reduction in brain edema." | 3.80 | Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S, 2014) |
| "Findings of the present study provide significant evidence that Piroxicam acts as a potent AQP4 regulator and renders neuroprotection in focal cerebral ischemia." | 3.79 | Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. ( Bhattacharya, P; Pandey, AK; Patnaik, R; Paul, S; Yavagal, DR, 2013) |
| "We investigated whether treatment with the nitric oxide synthase inhibitor N-nitro-L-arginine (L-NA) and the free radical scavenger superoxide dismutase influences cerebral blood flow changes, brain edema, and cerebrospinal fluid pleocytosis in early experimental pneumococcal meningitis." | 3.69 | Experimental pneumococcal meningitis: cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide. ( Bernatowicz, A; Fontana, A; Frei, K; Koedel, U; Paul, R; Pfister, HW, 1995) |
| "Brain edema was determined by means of the wet-dry weight method and assessed with light microscopy on H&E-stained preparations of tissues obtained 6 and 24 hours after glyceryl trinitrate treatment." | 1.42 | Effects of nitric oxide on blood-brain barrier permeability in common carp (Cyprinus carpio L.). ( Gjurcevic, E; Ivkic, G; Klaric, MŠ; Kovacić, S; Rumora, L, 2015) |
| " Among the causative factors of BBB disruption are accelerating peroxynitrite formation and the resultant decreased bioavailability of nitric oxide (NO)." | 1.38 | The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke. ( Dhammu, TS; Gilg, AG; Khan, M; Sakakima, H; Shunmugavel, A; Singh, AK; Singh, I, 2012) |
| "We concluded that curcumin ameliorates cerebral ischemia/reperfusion injury by preventing ONOO(-) mediated blood-brain barrier damage." | 1.34 | Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. ( Hu, M; Jiang, J; Li, F; Sun, YJ; Wang, W; Zhu, DY, 2007) |
| "LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier." | 1.34 | Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007) |
| "Melatonin treatment increased survival and reduced hyperactivity linked to neurodegeneration induced by cerebral ischemia and reperfusion." | 1.31 | Protective effects of melatonin in ischemic brain injury. ( Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharya, P | 2 |
| Pandey, AK | 2 |
| Paul, S | 2 |
| Patnaik, R | 2 |
| Yavagal, DR | 1 |
| Kovacić, S | 1 |
| Rumora, L | 1 |
| Gjurcevic, E | 1 |
| Klaric, MŠ | 1 |
| Ivkic, G | 1 |
| Dohare, P | 1 |
| Garg, P | 1 |
| Jain, V | 1 |
| Nath, C | 1 |
| Ray, M | 1 |
| Nagakannan, P | 1 |
| Shivasharan, BD | 1 |
| Thippeswamy, BS | 1 |
| Veerapur, VP | 1 |
| Bansal, P | 1 |
| Khan, M | 1 |
| Dhammu, TS | 1 |
| Sakakima, H | 1 |
| Shunmugavel, A | 1 |
| Gilg, AG | 1 |
| Singh, AK | 1 |
| Singh, I | 1 |
| Temiz, C | 1 |
| Tun, K | 1 |
| Ugur, HC | 1 |
| Dempsey, RJ | 1 |
| Egemen, N | 1 |
| Yatsushige, H | 1 |
| Calvert, JW | 1 |
| Cahill, J | 1 |
| Zhang, JH | 1 |
| Jiang, J | 1 |
| Wang, W | 1 |
| Sun, YJ | 1 |
| Hu, M | 1 |
| Li, F | 1 |
| Zhu, DY | 1 |
| Wright, G | 1 |
| Davies, NA | 1 |
| Shawcross, DL | 1 |
| Hodges, SJ | 1 |
| Zwingmann, C | 1 |
| Brooks, HF | 1 |
| Mani, AR | 1 |
| Harry, D | 1 |
| Stadlbauer, V | 1 |
| Zou, Z | 2 |
| Williams, R | 1 |
| Davies, C | 1 |
| Moore, KP | 1 |
| Jalan, R | 1 |
| Koedel, U | 1 |
| Bernatowicz, A | 1 |
| Paul, R | 1 |
| Frei, K | 1 |
| Fontana, A | 1 |
| Pfister, HW | 1 |
| Master, S | 1 |
| Gottstein, J | 1 |
| Blei, AT | 1 |
| Calapai, G | 2 |
| Marciano, MC | 2 |
| Corica, F | 1 |
| Allegra, A | 1 |
| Parisi, A | 2 |
| Frisina, N | 1 |
| Caputi, AP | 4 |
| Buemi, M | 1 |
| Cuzzocrea, S | 2 |
| McDonald, MC | 1 |
| Mazzon, E | 2 |
| Siriwardena, D | 1 |
| Costantino, G | 2 |
| Fulia, F | 2 |
| Cucinotta, G | 1 |
| Gitto, E | 2 |
| Cordaro, S | 2 |
| Barberi, I | 2 |
| De Sarro, A | 2 |
| Thiemermann, C | 1 |
| Serraino, I | 1 |
| Crupi, A | 1 |
| Firenzuoli, F | 1 |
| Squadrito, F | 1 |
| Inferrera, G | 1 |
| Rizzo, A | 1 |
| Crisafulli, C | 1 |
| Fiore, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Shuxuening Injection for the Prevention of Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage -- A Randomized, Double-blind, Placebo-parallel Controlled Clinical Trial[NCT06138353] | Phase 2/Phase 3 | 50 participants (Anticipated) | Interventional | 2023-11-13 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 other studies available for nitrites and Brain Swelling
| Article | Year |
|---|---|
Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents.
Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Calcium; Dose-Response R | 2013 |
Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia.
Topics: Animals; Antioxidants; Apoptosis; Aquaporin 4; Blotting, Western; Brain Edema; Brain Ischemia; Calci | 2014 |
Effects of nitric oxide on blood-brain barrier permeability in common carp (Cyprinus carpio L.).
Topics: Animals; Blood-Brain Barrier; Brain Edema; Carps; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; P | 2015 |
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea | 2008 |
Protective effect of hydroalcoholic extract of Mimusops elengi Linn. flowers against middle cerebral artery occlusion induced brain injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Blood-Brain Barrier; Brain Edema; | 2012 |
The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Carrier Proteins; Disease Models, Animal; E-Select | 2012 |
L-arginine in focal cerebral ischemia.
Topics: Animals; Arginine; Brain Edema; Brain Ischemia; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitr | 2003 |
Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Male; Nitrates | 2006 |
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Capillaries; Curcuma; Curcumi | 2007 |
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C | 2007 |
Experimental pneumococcal meningitis: cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Brain Edema; Cells, Cultured; Cerebral Ar | 1995 |
Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis.
Topics: Ammonia; Animals; Brain; Brain Edema; Cerebrovascular Circulation; Cranial Sinuses; Hemodynamics; In | 1999 |
Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation.
Topics: Aldehydes; Animals; Brain; Brain Edema; Brain Ischemia; Erythropoietin; Gerbillinae; Humans; Injecti | 2000 |
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Edema; Cerebral Arteries; Cyclic N-Oxides; Free R | 2000 |
Protective effects of melatonin in ischemic brain injury.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scaveng | 2000 |
Neuroprotective effects of Ginkgo biloba extract in brain ischemia are mediated by inhibition of nitric oxide synthesis.
Topics: Administration, Oral; Animals; Brain; Brain Edema; Cell Death; Dose-Response Relationship, Drug; Ger | 2000 |