Page last updated: 2024-10-19

nitrites and Body Weight

nitrites has been researched along with Body Weight in 238 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0."7.96The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020)
"Chronic inflammation accompanied by arginine deficiency, immune dysfunction, and excess nitric oxide (NO) production is a clinical condition found in patients with peritonitis."7.78The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester in rats with sub-acute peritonitis. ( Hsiao, CC; Lee, CH; Lo, HC; Tsao, LY, 2012)
" In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice."7.74Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
"To assess the antioxidant effects of atorvastatin (atorva) on dexamethasone (dex)-induced hypertension, 60 male Sprague-Dawley rats were treated with atorva 30 mg/kg/day or tap water for 15 days."7.73Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat. ( Huang, TG; Mondo, CK; Su, JZ; Yang, WS, 2006)
"NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis."7.72NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."7.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
" Subsequently, the effects of L-arginine, D-arginine or L-arginine + N-nitro-L-arginine (NOLA) on corticosterone-induced hypertension (corticosterone 20 mg/kg per day) were examined."7.70The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. ( Fraser, TB; Mangos, GJ; Turner, SW; Whitworth, JA, 2000)
"Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid."5.42Orally administered allyl sulfides from garlic ameliorate murine colitis. ( Borrelli, F; Clavel, T; Fasolino, I; Haller, D; Izzo, AA; Romano, B, 2015)
"Currently, obesity is considered a systemic inflammation; however, the effects of obesity on the vulnerability of dopaminergic neurons to oxidative stress are not fully defined."5.33Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity. ( Choi, JY; Jang, EH; Kang, JH; Park, CS, 2005)
"Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0."3.96The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020)
"The present study was aimed to evaluate the antihypertensive effect of diosmin in deoxycorticosterone acetate (DOCA)-salt induced hypertension in male Wistar rats."3.78Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats. ( Raja, B; Silambarasan, T, 2012)
"Chronic inflammation accompanied by arginine deficiency, immune dysfunction, and excess nitric oxide (NO) production is a clinical condition found in patients with peritonitis."3.78The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester in rats with sub-acute peritonitis. ( Hsiao, CC; Lee, CH; Lo, HC; Tsao, LY, 2012)
"This study investigated the effects of indole-3-carbinol (I3C), a compound from cruciferous vegetables, on various parameters related to obesity, in particular, the parameters of infiltration by macrophages and of inflammatory cytokines expressed during the co-culture of adipocytes and macrophages."3.77Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes. ( Chan, MH; Chang, HP; Chen, YH; Hsu, CY; Liu, ME; Wang, ML, 2011)
" This study addressed whether rosiglitazone (ROSI), a PPARgamma agonist, attenuates salt-sensitive hypertension in intact (INT) and OVX DS rats, and if so, whether insulin resistance, nitric oxide (NO), oxidative stress, and/or renal inflammation were contributing mediators."3.76Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats. ( Jones, AV; Lamarca, BB; Racusen, LC; Reckelhoff, JF; Romero, DG; Ryan, MJ; Sartori-Valinotti, JC; Venegas-Pont, MR; Yanes, LL, 2010)
" In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice."3.74Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
" The evolution of systolic blood pressure was followed by weekly measurements, and morphological variables, proteinuria, plasma nitrates plus nitrites (NOx) and thiobarbituric acid reactive substances (TBARS), liver oxidative stress markers and endothelial function were determined at the end of the experimental period."3.73Effects of chronic quercetin treatment in experimental renovascular hypertension. ( Bermejo, A; Duarte, J; Galisteo, M; García-Saura, MF; Vargas, F; Villar, IC; Zarzuelo, A, 2005)
"To assess the antioxidant effects of atorvastatin (atorva) on dexamethasone (dex)-induced hypertension, 60 male Sprague-Dawley rats were treated with atorva 30 mg/kg/day or tap water for 15 days."3.73Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat. ( Huang, TG; Mondo, CK; Su, JZ; Yang, WS, 2006)
"Normal and streptozotocin-induced diabetic rats of two different strains (U and H) were given intraperitoneal (IP) injections of the angiogenesis inhibitor Suramin (Sigma Chemical Co, St Louis, MO) or saline in early pregnancy, and fed standard or vitamin E-enriched food."3.73Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment. ( Eriksson, UJ; Nash, P; Olovsson, M, 2005)
"NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis."3.72NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003)
" Body weight, urinary pyridinoline (Pyr), deoxypyridinoline (DPyr) corrected for urinary creatinine, serum nitrite/nitrate concentrations and whole body and femoral bone mineral density (BMD) were measured."3.72The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia. ( Istok, R; Rovenský, J; Stancíková, M; Svík, K; Velebný, V, 2004)
"Losartan, an angiotensin II type-1 receptor (AT1) antagonist, was used to investigate whether it can offer protection against the sustained hypertension, cardiac hypertrophy, and renal damage induced by chronic inhibition of nitric oxide (NO) by Nomega-nitro-L-arginine methyl ester (L-NAME)."3.72Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats. ( Ahmad, M; Al-Shabanah, OA; Khattab, M; Raza, M, 2004)
" This study analyses the contribution of the precursor L-arginine (L-arg) by oral administration in two kidney-two clip hypertension in the rat (2K-2C)."3.70Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats. ( Albornoz, LE; Damiano, PF; de la Riva, IJ; Ferrero, AJ; Palumbo, EL; Rosón, MI; Speziale, N; Vega, GW, 2000)
" Subsequently, the effects of L-arginine, D-arginine or L-arginine + N-nitro-L-arginine (NOLA) on corticosterone-induced hypertension (corticosterone 20 mg/kg per day) were examined."3.70The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. ( Fraser, TB; Mangos, GJ; Turner, SW; Whitworth, JA, 2000)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."3.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
" We examined the hypothesis that HC may inhibit ischemia-induced angiogenesis by inhibition of EDNO in a rat model of unilateral hindlimb ischemia and that oral L-arginine supplementation, a substrate for NO synthase, may prevent HC-related impairment of angiogenesis."3.70Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. ( Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N, 2000)
"The available data on the role of the L-arginine/nitric oxide (NO) pathway in the genesis of hypertension in spontaneously hypertensive rats (SHR) are limited and contradictory."3.70Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats. ( Ni, Z; Oveisi, F; Vaziri, ND, 1998)
"Aging is associated with loss of nephron function and reductions in serum L-arginine and excretion of nitric oxide (NO) metabolites."3.69Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function. ( Hildebrandt, DA; Kellum, JA; Racusen, LC; Reckelhoff, JF, 1997)
" The NB diet provoked body weight and feeding efficiency enhancement with a reduction in body density increasing serum lactic acid, uric acid and cholesterol levels."3.69Dietary nitrite and scavenger antioxidants trace elements. ( de Angelis, RC; Klemps, I; Scialfa, JH; Terra, IC, 1996)
"We have previously shown beneficial effects of dietary protein restriction on transforming growth factor beta (TGF-beta) expression and glomerular matrix accumulation in experimental glomerulonephritis."3.69L-arginine may mediate the therapeutic effects of low protein diets. ( Border, WA; Ketteler, M; Narita, I; Noble, NA; Ruoslahti, E, 1995)
"Sodium nitrite administered in the drinking water to Long-Evans rats during pregnancy and lactation severely affected erythropoietic development, growth, and mortality in their offspring."3.67Evaluation of the developmental toxicity of sodium nitrite in Long-Evans rats. ( Bercz, JP; Herkert, GE; Roth, AC; Smith, MK, 1987)
"The effects of subchronic inhalation exposure to isobutyl nitrite (IBN) on body weight, selected organ weights, hematology, and gross pathology and histopathology of BALB/c mice were evaluated."3.67Subchronic inhalation toxicity of isobutyl nitrite in BALB/c mice. I. Systemic toxicity. ( Burg, JR; Chandler, FW; Khan, A; Kimbrough, RD; Lewis, DM; Lewis, TR; Lynch, DW; Moorman, WJ; Phipps, FC; Spira, TJ, 1985)
"Parkinson's disease is a neurodegenerative disorder that affects the central nervous system and is mainly characterized by the loss of dopaminergic neurons and pro-oxidant mechanisms."1.56Eugenol and its association with levodopa in 6-hydroxydopamine-induced hemiparkinsonian rats: Behavioural and neurochemical alterations. ( Aragão Catunda Junior, FE; Basto Souza, R; da Cunha Ferreira, NM; de Sousa Dos Reis, TD; Hardy Lima Pontes, N; Maranguape Silva da Cunha, R; Moreira Vasconcelos, CF; Vasconcelos Aguiar, LM, 2020)
"Body weight was measured weekly."1.48Effect of long-term nitrite administration on browning of white adipose tissue in type 2 diabetic rats: A stereological study. ( Abdollahifar, MA; Ghasemi, A; Haeri Rohani, SA; Jeddi, S; Piryaei, A; Varzandi, T; Zadeh-Vakili, A, 2018)
"Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type 2 diabetes."1.46Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats. ( Bakhtiarzadeh, F; Farrokhfall, K; Ghasemi, A; Gheibi, S; Jeddi, S; Zardooz, H, 2017)
"Curcumin was better absorbed systemically in nanoparticulate form with increased Cmax (∼3 fold) and AUC (∼2."1.43Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. ( Avadhani, K; Kalthur, G; Kulkarni, RV; Managuli, RS; Mutalik, S; Shetty, PK; Suthar, NA; Thomas, R, 2016)
" Chronic administration of haloperidol significantly increased oxidative stress and neuro-inflammation in the striatum region of the rat's brain."1.42Beneficial effect of candesartan and lisinopril against haloperidol-induced tardive dyskinesia in rat. ( Bansal, PK; Bisht, R; Prakash, A; Thakur, KS, 2015)
"Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid."1.42Orally administered allyl sulfides from garlic ameliorate murine colitis. ( Borrelli, F; Clavel, T; Fasolino, I; Haller, D; Izzo, AA; Romano, B, 2015)
"The anticancer drug; doxorubicin (DOX), causes testicular toxicity as an adverse effect."1.40Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity. ( El-Sheikh, AA; Mahmoud, MM; Morsy, MA; Rifaai, RA, 2014)
"Chromatolysis and amyloid plaques were found along with higher ROS, nitrite and TNF-α levels in the hippocampus of colchicine-induced AD rats, and these changes were prevented by naproxen in a dose-dependent manner."1.40Effects of naproxen on immune responses in a colchicine-induced rat model of Alzheimer's disease. ( Dutta, G; Ghosh, T; Goswami, AR; Sil, S, 2014)
"Huntington's disease is a progressive neurodegenerative disorder that gradually reduces memory, cognitive skills and normal movements of affected individuals."1.38Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity. ( Kalonia, H; Kumar, A; Kumar, P, 2012)
"Fenofibrate treatment significantly attenuated oxidative damage, cytokines and improved mitochondrial complexes enzyme activity in brain."1.38Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms. ( Bhateja, DK; Dhull, DK; Gill, A; Padi, SS; Reddy, BV; Sharma, S; Sidhu, A, 2012)
"Treatment with sodium nitrite (NO donor), L: -arginine (NO precursor), daidzein (caveolin inhibitor), and combination of L: -arginine and daidzein for 2 weeks markedly attenuated these changes and increased serum nitrite/nitrate ratio."1.37Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats. ( Arya, A; Sharma, PL; Yadav, HN, 2011)
"Huntington disease is a neurodegenerative disease with complex pathophysiology."1.37Attenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats. ( Kalonia, H; Kumar, A; Kumar, P, 2011)
"Olprinone is a specific phosphodiesterase (PDE)-III inhibitor, which has been found to have anti-inflammatory effects in addition to its main inotropic and peripheral vasodilatory effects."1.37Olprinone, a specific phosphodiesterase (PDE)-III inhibitor, reduces the development of multiple organ dysfunction syndrome in mice. ( Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Impellizzeri, D; Mazzon, E, 2011)
"Hyperlipidemia, thrombosis and oxidative stress are the primary underlying concerns in the pathogenesis of atherosclerosis."1.37Investigation of the potential effects of metformin on atherothrombotic risk factors in hyperlipidemic rats. ( Bhadada, SV; Dhamecha, PS; Ghatak, SB; Panchal, SJ, 2011)
" When combined at a dosage either positively or negatively skewed from each optimal dosage, however, co-treatment caused synergistic neuroprotection."1.37Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response. ( Chen, HY; Chen, TY; Huang, SY; Hung, YC; Lee, AC; Lee, EJ; Lee, MY; Shen, CC; Tai, SH; Wu, TS, 2011)
"8 mg/kg, the adverse effect was not observed, and the target organ was liver."1.37[Study on acute and subchronic toxicity of ammonium dinitramide]. ( Chang, ZQ; Du, WX; Sun, YH; Wang, YL; Xie, F; Xing, YF; Zhang, YW, 2011)
"Quinolinic acid has been reported to induce excitotoxicity by stimulating the N-methyl-D-aspartate receptor, causing calcium overload which in turn leads to the neurodegeneration."1.36Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2010)
"Treatment with alprazolam (0."1.35Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
" Importantly, both exercise protocols improved endothelial-dependent vasodilatation and NO bioavailability without altering hyperglycaemic status in db/db mice."1.35Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice. ( Brownsey, RW; Elmi, S; Ghosh, S; Khazaei, M; Kieffer, TJ; Laher, I; Moien-Afshari, F; Rahman, MM; Sallam, N, 2008)
") injection of 55 mg/kg STZ and a nicotinamide group (1g/kg/day) which were dosed orally for 3 days followed by (i."1.35Effect of nicotinamide on experimental induced diabetes. ( Alenzi, FQ, 2009)
"Problems of sleep deprivation are increasing in modern society nowadays."1.35Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
"Captopril treatment reversed the increments in pressure back to normal values by the fourth week."1.33Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat. ( Al-Shabanah, O; Khattab, MM; Mostafa, A, 2005)
"Obesity has emerged as a major cause of diabetes, cardiovascular disease, and renal insufficiency worldwide."1.33Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin. ( Li, Z; Ni, Z; Rodríguez-Iturbe, B; Sepassi, L; Shahkarami, A; Vaziri, ND, 2005)
"Diabetic mice exhibited significant hyperalgesia along with increased plasma glucose and decreased body weights as compared with control mice."1.33Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain. ( Agrewala, JN; Chopra, K; Kulkarni, SK; Sharma, S, 2006)
"Currently, obesity is considered a systemic inflammation; however, the effects of obesity on the vulnerability of dopaminergic neurons to oxidative stress are not fully defined."1.33Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity. ( Choi, JY; Jang, EH; Kang, JH; Park, CS, 2005)
"Whether rHuEpo treatment in ESRD is accompanied by alterations in NO production was explored in patients undergoing hemodialysis."1.31Biphasic changes in nitric oxide generation in hemodialyzed patients with end-stage renal disease treated with recombinant human erythropoietin. ( Acchiardo, SR; Cardenas, R; Kang, ES; Mishra, S; Tevlin, MT; Wang, YB, 2000)
"Treatment with nicardipine (20 mg/kg/day, s."1.31Antioxidant enzyme activities and total nitrite/nitrate levels in the collar model. Effect of nicardipine. ( Kerry, Z; Onat, T; Sözmen, EY; Ustünes, L; Uysal, F; Yasa, M; Yetik, G, 2000)
"Using this model of cerebrovascular stroke, influence of stroke-onset on the autonomic nervous system was investigated."1.31Disturbance of circadian rhythm in heart rate, blood pressure and locomotive activity at the stroke-onset in malignant stroke-prone spontaneously hypertensive rats. ( Ikeda, M; Ito, T; Suzuki, M; Tabuchi, M; Tomita, T; Umegaki, K, 2001)
"The ozone treatment improved glycemic control and prevented oxidative stress, the increase of aldose reductase, fructolysine content and advanced oxidation protein products."1.31Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats. ( Al-Dalain, SM; Candelario-Jalil, E; Giuliani, A; León, OS; Martínez, G; Menéndez, S; Re, L, 2001)
" Chronic administration of L-NAME to rats induced reduced NO production and hypertension in both strains of rats."1.31Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats. ( Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E, 2002)
"Hemorrhage is a major pathological manifestation of E."1.30Nitric oxide production during Eimeria tenella infections in chickens. ( Allen, PC, 1997)
"Erythromycin (EM) is an antibiotic with potent antiinflammatory effects that is used for treating chronic lower respiratory tract infections."1.30Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice. ( Akaike, T; Ando, M; Doi, T; Fujii, S; Maeda, H; Muranaka, H; Sato, K; Suga, M, 1998)
"This study documents that trauma induces alterations in the inflammatory cytokine cascade that affect the immune response to subsequent septic challenges."1.29Polymicrobial sepsis following trauma inhibits interleukin-10 secretion and lymphocyte proliferation. ( Campbell, C; Napolitano, LM, 1995)
"Nitrates were found to originate mainly from vegetables (80%), nitrites from meat products (97%) and nitrosamines mostly from fish products and beer."1.28Nitrate, nitrite, and N-nitroso compounds in Finnish foods and the estimation of the dietary intakes. ( Kimppa, S; Penttilä, PL; Räsänen, L, 1990)
"It is known that sodium nitrite and dimethylamine are toxic compounds, which may react to form dimethylnitrosamine in the gastro-intestinal tract, a much more toxic compound and a powerful cancerogen."1.27The toxicity of the daily intake of nitrite and dimethylamine. ( Ballenilla, T; Cabrera, Y; Castillo, A; García Roché, M; Silva, V, 1983)
" Additional prior dosing with Opisthorchis viverrini metacercariae (100/animal) induced inflammatory and proliferative changes in the livers of infected hamsters and was associated with a significant increase in yields of hepatocellular and cholangiocellular preneoplastic and neoplastic lesions."1.27Generation of high yields of Syrian hamster cholangiocellular carcinomas and hepatocellular nodules by combined nitrite and aminopyrine administration and Opisthorchis viverrini infection. ( Hiasa, Y; Ito, N; Moore, MA; Thamavit, W, 1988)
" NaNO2 produced a moderate degree of developmental toxicity, but no evidence was found to suggest that the central nervous system was the target organ for the toxic effects."1.27Developmental toxicity and psychotoxicity of sodium nitrite in rats. ( Brunner, RL; Butcher, RE; Vorhees, CV; Wootten, V, 1984)

Research

Studies (238)

TimeframeStudies, this research(%)All Research%
pre-199042 (17.65)18.7374
1990's32 (13.45)18.2507
2000's86 (36.13)29.6817
2010's72 (30.25)24.3611
2020's6 (2.52)2.80

Authors

AuthorsStudies
Yang, F3
Shi, X2
Yang, W1
Gao, C2
Cui, Z1
Wang, W3
Moretti, C1
Zhuge, Z1
Zhang, G2
Haworth, SM1
Paulo, LL1
Guimarães, DD1
Cruz, JC1
Montenegro, MF1
Cordero-Herrera, I1
Braga, VA1
Weitzberg, E1
Carlström, M1
Lundberg, JO1
Mayyas, FA1
Aljohmani, AI1
Alzoubi, KH1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y3
Wang, J6
Huang, L2
Hu, K1
Liu, H4
Wang, H3
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X4
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J4
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J2
Jiang, H1
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X5
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z3
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Zhang, X6
Xu, N1
Wang, R1
Liu, S1
He, H1
Dong, X2
Yang, M2
Yang, Q2
Duan, S1
Yu, Y2
Han, J2
Zhang, C3
Chen, L2
Yang, X1
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H5
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ3
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
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Sakashita, T1
Tsuda, M1
Ohama, K1
Riveiro, A1
Mosquera, A1
Calvo, C1
Alonso, M1
Macía, M1
Cores, M1
Duplain, H1
Burcelin, R1
Sartori, C1
Cook, S1
Egli, M1
Lepori, M1
Vollenweider, P1
Pedrazzini, T1
Nicod, P1
Thorens, B1
Scherrer, U1
Mori, S1
Mitarai, G1
Takagi, S1
Takabayashi, A1
Usui, S1
Nakamura, T1
Sakakibara, M1
Nagatomo, M1
von Baumgarten, RJ1
Nagaoka, S1
Matsubara, S1
Kato, M1
Uchida, S1
Uemura, M1
Sakimura, T1
Ogawa, N1
Nakamura, HK1
Hosogai, N1
Seki, J1
Goto, T1
Eriksson, AS1
Järvinen, AK1
Eklund, KK1
Vuolteenaho, OJ1
Toivari, MH1
Nieminen, MS1
Al-Dalain, SM1
Martínez, G1
Candelario-Jalil, E1
Menéndez, S1
Re, L1
Giuliani, A1
León, OS1
Trachtman, H1
Futterweit, S1
Pine, E1
Mann, J1
Valderrama, E1
Goto, H1
Shimada, Y1
Kita, T1
Shibahara, N1
Terasawa, K1
Ishimura, N1
Takishita, E1
Takahashi, A1
Kuru, O1
Sentürk, UK1
Demir, N1
Yeşilkaya, A1
Ergüler, G1
Erkiliç, M1
Gerbeaux, J1
Tournier, G1
Labrune, B1
Berende, PL1
Terluin, RW1
van der Wal, P1
Lhuissier, M1
Vernevaut, MF1
Matthies, E1
Pankow, D1
Ponsold, W1
Anderson, LM2
Giner-Sorolla, A2
Ebeling, D1
Bilczuk, L1
Schweinsberg, F3
Schott-Kollat, P1
Majchrzak, D1
Gronowska-Senger, A1
Penttilä, PL1
Räsänen, L1
Kimppa, S1
Thamavit, W1
Moore, MA1
Hiasa, Y1
Ito, N1
Hilmy, AM1
el-Domiaty, NA1
Wershana, K1
McFadden, DP1
Maickel, RP1
Dvorák, M1
Lewis, DM2
Lynch, DW2
Til, HP1
Falke, HE1
Kuper, CF1
Willems, MI1
Roth, AC1
Herkert, GE1
Bercz, JP1
Smith, MK1
Haller, IM1
Budinger, JM1
Moorman, WJ1
Burg, JR1
Phipps, FC1
Lewis, TR1
Chandler, FW1
Kimbrough, RD1
Spira, TJ1
Musil, J1
Procházka, J1
Krofta, K1
Rakusan, K1
Poupa, O1
Sander, J3
Bürkle, G1
van Logten, MJ1
den Tonkelaar, EM1
Kroes, R1
Berkvens, JM1
van Esch, GJ1
Schneider, B1
Selenka, F1
Kamm, JJ1
Dashman, T1
Conney, AH1
Burns, JJ1
Stoewsand, GS1
Anderson, JL1
Lee, CY1
Bolyai, JZ1
Gray, CT1
Uzoukwu, M1
Sleight, SD1
Menz, HP1
Iunusova, KhK1
Fedorova, VI1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Production of Fortified Biscuit With Chickpea and Crushed Peanut and Evaluating Its Effectiveness in Terms of Its Acceptability and Cognitive Performance: a Pilot Study Among Egyptian Primary School-aged Children[NCT05281146]80 participants (Actual)Interventional2018-11-26Completed
The Health Effects of a Blueberry Enriched Diet on Obese Children: A Feasibility Study[NCT01809795]10 participants (Actual)Interventional2013-03-31Completed
The Effect of Nitrate Supplementation on Sport Performance: High Intensity Intermittent Performance in Recreational Athletes[NCT02436629]Phase 440 participants (Actual)Interventional2015-05-31Completed
Insulin Resistance in Nonalcoholic Fatty Liver Disease: A Case Control Study[NCT00637520]29 participants (Actual)Observational2007-07-31Terminated
Clinical Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention[NCT01192204]Phase 1/Phase 241 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Lesional Sizes

The remaining oral dysplasia lesion will be inspected at each follow up appointment (every 10-14 days). Biopsies will be immediately conducted on patients with any indication of malignant transformation including indurated, rolled borders, nonhealing ulcers, etc. Accordingly, these patients will withdraw from the trial. Participants will also be monitored for any changes consistent with contact mucositis e.g. soreness and erythema at application site. Clinical photographs were taken for the patients records. Pre treatment and post treatment photographs, with a ruler in place, were used for accurate pre and post treatment size measurement. NOTE: if treatment is beneficial, lesional size will decrease which will be reflected as a negative number. (NCT01192204)
Timeframe: pretreatment and posttreatment (3 months treatment duration)

Interventionmm^2 (Mean)
10% FBR Gel-26.12
Placebo Gel18.12

Treatment Changes in Loss of Heterozygosity Events

Laboratory experiments will be conducted to assess the effects of gel treatment on pre and post loss of heterozygosity (LOH) events at loci associated with tumor suppressor genes. (NCT01192204)
Timeframe: Before and after the 3 month treatment duration

InterventionLOH events (Mean)
10% FBR Gel0.9
Placebo Gel0.4

Light Microscopic Histologically Scored Diagnoses Pretreatment to Post Treatment

A hemisection of lesional tissue will be conducted before the 3 month treatment to establish a diagnosis and provide a pretreatment baseline for the experimental parameters. Anl excisional biopsy of the treatment site including any remaining residual lesional tissue (excision of oral dysplastic lesions is consistent with current standards of care) will be obtained after 3 months of treatment to provide a posttreatment diagnosis. The 0 to 8 histologic scale was:0=normal with or without hyperkeratosis BEST OUTCOME, 1=atypia, 2=mild dysplasia, 3=mild-moderate dysplasia, 4=moderate dysplasia,5=moderate-severe dysplasia,6=severe dysplasia, 7=carcinoma in situ, 8=invasive oral squamous cell carcinoma (WORST OUTCOME). (NCT01192204)
Timeframe: Before and after the 3 month treatment.

,
Interventionunit on histologic grade scale (Mean)
PretreatmentPosttreatment
10% FBR Gel2.361.9
Placebo Gel2.832.58

Reviews

2 reviews available for nitrites and Body Weight

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
[Pediatrics in 1976].
    La Revue du praticien, 1977, Jan-21, Volume: 27, Issue:5

    Topics: Adolescent; alpha 1-Antitrypsin Deficiency; Body Weight; Carcinoma, Hepatocellular; Catheterization;

1977

Trials

9 trials available for nitrites and Body Weight

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Simultaneous Pharmacokinetic Analysis of Nitrate and its Reduced Metabolite, Nitrite, Following Ingestion of Inorganic Nitrate in a Mixed Patient Population.
    Pharmaceutical research, 2020, Nov-02, Volume: 37, Issue:12

    Topics: Administration, Oral; Aged; Aging; Biological Availability; Body Weight; Cross-Over Studies; Dietary

2020
Beetroot Juice Supplementation Improves High-Intensity Intermittent Type Exercise Performance in Trained Soccer Players.
    Nutrients, 2017, Mar-22, Volume: 9, Issue:3

    Topics: Athletic Performance; Beta vulgaris; Body Height; Body Weight; Cross-Over Studies; Double-Blind Meth

2017
The role of sustained release isosorbide mononitrate on corticosteroid-induced hypertension in healthy human subjects.
    Journal of human hypertension, 2015, Volume: 29, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight;

2015
Beetroot juice increase nitric oxide metabolites in both men and women regardless of body mass.
    International journal of food sciences and nutrition, 2016, Volume: 67, Issue:1

    Topics: Adult; Beta vulgaris; Blood Pressure; Body Weight; Female; Fruit and Vegetable Juices; Humans; Male;

2016
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children.
    International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity, 2009, Volume: 4, Issue:4

    Topics: Arginine; Biomarkers; Blood Glucose; Blood Pressure; Body Height; Body Mass Index; Body Weight; Brac

2009
Dietary nitrate supplementation improves rowing performance in well-trained rowers.
    International journal of sport nutrition and exercise metabolism, 2012, Volume: 22, Issue:4

    Topics: Adolescent; Athletes; Beta vulgaris; Blood Pressure; Body Weight; Cross-Over Studies; Diet Records;

2012
Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women.
    The Journal of nutrition, 2006, Volume: 136, Issue:9

    Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind

2006
Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man.
    Journal of hypertension, 1999, Volume: 17, Issue:12 Pt 1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Blood Pressure; Body Weight; Cardiovascular P

1999

Other Studies

228 other studies available for nitrites and Body Weight

ArticleYear
Pueraria montana (Kudzu vine) Ameliorate the Inflammation and Oxidative Stress against Fe-NTA Induced Renal Cancer.
    Journal of oleo science, 2022, Sep-30, Volume: 71, Issue:10

    Topics: Animals; Antioxidants; Biomarkers, Tumor; Body Weight; Creatinine; Cyclooxygenase 2; Diethylnitrosam

2022
The obligatory role of host microbiota in bioactivation of dietary nitrate.
    Free radical biology & medicine, 2019, Volume: 145

    Topics: Animals; Blood Pressure; Body Weight; Cardiovascular Diseases; Cardiovascular System; Diet, Western;

2019
The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats.
    Current molecular pharmacology, 2020, Volume: 13, Issue:3

    Topics: Aldosterone; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Cardiovascular Diseases

2020
Eugenol and its association with levodopa in 6-hydroxydopamine-induced hemiparkinsonian rats: Behavioural and neurochemical alterations.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 127, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Disease Models, Animal; Eugenol; Glutathione; Levodop

2020
Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure.
    Clinical science (London, England : 1979), 2020, 10-30, Volume: 134, Issue:20

    Topics: Animals; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cationic Amino Acid Transporter 1; En

2020
AB569, a Novel, Topical Bactericidal Gel Formulation, Kills Pseudomonas aeruginosa and Promotes Wound Healing in a Murine Model of Burn Wound Infection.
    Infection and immunity, 2021, 10-15, Volume: 89, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Body Weight; Burns; Collagen; Disease Models, Animal; Edetic Acid; G

2021
Effects of supplementation with spray-dried porcine plasma on blood variables on piglets feed with diet contaminated by mycotoxins.
    Microbial pathogenesis, 2017, Volume: 110

    Topics: Aflatoxins; Animals; Blood Chemical Analysis; Body Weight; C-Reactive Protein; Dietary Supplements;

2017
Nitric oxide synthase inhibition impairs muscle regrowth following immobilization.
    Nitric oxide : biology and chemistry, 2017, Sep-30, Volume: 69

    Topics: Animals; Body Weight; Hindlimb Suspension; Imidazoles; Male; Muscle, Skeletal; Muscular Atrophy; NG-

2017
Oxidative Biochemistry Disbalance and Changes on Proteomic Profile in Salivary Glands of Rats Induced by Chronic Exposure to Methylmercury.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Antioxidants; Body Weight; Chromatography, High Pressure Liquid; Lipid Peroxidation; Male;

2017
Chronic Intermittent Hypobaric Hypoxia (4600 M) Attenuates Pulmonary Vasodilation Induced by Acetylcholine or Sodium Nitroprusside.
    High altitude medicine & biology, 2018, Volume: 19, Issue:2

    Topics: Acetylcholine; Altitude; Altitude Sickness; Animals; Blood Pressure; Body Weight; Chronic Disease; D

2018
Linalyl acetate prevents olmesartan-induced intestinal hypermotility mediated by interference of the sympathetic inhibitory pathway in hypertensive rat.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Animals; Blood Pressure; Body Weight; Cell Size; Epithelial Cells; Gastrointestinal Motility; Heart

2018
Effect of long-term nitrite administration on browning of white adipose tissue in type 2 diabetic rats: A stereological study.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Cyclic GMP; Diabetes

2018
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinkin

2013
Nitrite-induced alterations in sex steroids and thyroid hormones of Labeo rohita juveniles: effects of dietary vitamin E and L-tryptophan.
    Fish physiology and biochemistry, 2013, Volume: 39, Issue:5

    Topics: Analysis of Variance; Animals; Body Weight; Cyprinidae; Dietary Supplements; Gonadal Steroid Hormone

2013
Nitric oxide mediates the insulin sensitizing effects of β-sitosterol in high fat diet-fed rats.
    Nitric oxide : biology and chemistry, 2013, Aug-01, Volume: 32

    Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Guanidines; Hepatocytes;

2013
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabet

2013
Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:3

    Topics: Animals; Antioxidants; Benzodioxoles; Body Weight; Colon; Dinitrochlorobenzene; Granulocyte Colony-S

2013
Sex differences in protective effect of recombinant human erythropoietin against cisplatin-induced nephrotoxicity in rats.
    Iranian journal of kidney diseases, 2013, Volume: 7, Issue:5

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Body Weight; Cisplatin; Cr

2013
Beneficial effect of candesartan and lisinopril against haloperidol-induced tardive dyskinesia in rat.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:4

    Topics: Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Body Weight; Grooming; Haloperidol; Hand

2015
Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Memb

2014
Effects of naproxen on immune responses in a colchicine-induced rat model of Alzheimer's disease.
    Neuroimmunomodulation, 2014, Volume: 21, Issue:6

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Brain; Colchicine;

2014
Catalase influence in the regulation of coronary resistance by estrogen: joint action of nitric oxide and hydrogen peroxide.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Animals; Antioxidants; Body Weight; Catalase; Coronary Vessels; Estrogens; Female; Hydrogen Peroxide

2014
Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:8

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Cholesterol; Dementia; Diet, High-Fat; Disease Mo

2014
Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Astrocytes; Body Weight; Cell Count; Cerebral Cortex; Ethanol; Lipid Peroxidation; Male; Mi

2014
Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKA(y) mice.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cytokines; Diabetes Mellitus, Experimental; Dia

2015
Orally administered allyl sulfides from garlic ameliorate murine colitis.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:3

    Topics: Administration, Oral; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulf

2015
Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats.
    Neuroscience, 2015, Feb-26, Volume: 287

    Topics: Animals; Body Weight; Corpus Striatum; Encephalitis; Glycogen Synthase Kinase 3; Glycogen Synthase K

2015
Brain delivery of intranasal in situ gel of nanoparticulated polymeric carriers containing antidepressant drug: behavioral and biochemical assessment.
    Journal of drug targeting, 2015, Volume: 23, Issue:3

    Topics: Administration, Intranasal; Animals; Antidepressive Agents; Body Weight; Brain; Catalase; Drug Carri

2015
Protective effect of leaf essential oil from Cinnamomum osmophloeum Kanehira on endotoxin-induced intestinal injury in mice associated with suppressed local expression of molecules in the signaling pathways of TLR4 and NLRP3.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Carrier Proteins; Cinnamomum; Cytokines; Disease Mod

2015
Neuroprotective potential of antioxidant potent fractions from Convolvulus pluricaulis Chois. in 3-nitropropionic acid challenged rats.
    Nutritional neuroscience, 2016, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Convolvulus; Corpus Striatum; Glutathione; Hun

2016
Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.
    The Journal of physiology, 2015, Jul-15, Volume: 593, Issue:14

    Topics: Animals; Blood Pressure; Body Weight; Cell Respiration; Insulin Resistance; Male; Metabolic Syndrome

2015
Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin.
    International journal of biological macromolecules, 2016, Volume: 86

    Topics: Acrylic Resins; Aluminum Chloride; Aluminum Compounds; Animals; Body Weight; Cell Survival; Chloride

2016
The Nitric Oxide Synthase Inhibitor NG-Nitro-L-Arginine Methyl Ester Diminishes the Immunomodulatory Effects of Parental Arginine in Rats with Subacute Peritonitis.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Arginine; Body Weight; Cytokines; Immunophenotyping; Male; NG-Nitro

2016
Orchidectomy attenuates high-salt diet-induced increases in blood pressure, renovascular resistance, and hind limb vascular dysfunction: role of testosterone.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:9

    Topics: Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Drinking; Hindlimb; Kidney;

2016
Effect of ruthenium red, a ryanodine receptor antagonist in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
    Physiology & behavior, 2016, 10-01, Volume: 164, Issue:Pt A

    Topics: Animals; Aorta; Blood Glucose; Body Weight; Brain; Calcium Channel Blockers; Dementia; Diabetes Mell

2016
Alzheimer's disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior.
    Neurological research, 2016, Volume: 38, Issue:9

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Anxiety; Body

2016
Preoperative vitamin C supplementation improves colorectal anastomotic healing and biochemical parameters in malnourished rats.
    International journal of colorectal disease, 2016, Volume: 31, Issue:11

    Topics: Anastomosis, Surgical; Animals; Ascorbic Acid; Body Weight; Collagen; Colon; Dietary Supplements; Hy

2016
Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats.
    Nitric oxide : biology and chemistry, 2017, Apr-01, Volume: 64

    Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Eating; Glucose; I

2017
Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice.
    American journal of physiology. Endocrinology and metabolism, 2017, 04-01, Volume: 312, Issue:4

    Topics: Animals; Body Weight; Chemokine CCL2; Diet; Diet, High-Fat; Eating; Fatty Liver; Female; Insulin Res

2017
Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:8

    Topics: Animals; Anxiety; Arginine; Behavior, Animal; Body Weight; Catalase; Curcumin; Dose-Response Relatio

2008
Assessment of dietary exposure of nitrate and nitrite in France.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2008, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Body Weight; Cheese; Child; Child, Preschool; Diet; Diet Records; Diet Surveys; F

2008
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:9

    Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze

2008
The effect of diabetes mellitus on active avoidance learning in rats: the role of nitric oxide.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:3

    Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Diabetes Mellitus; Drinking Behavior; Feedi

2009
Effect of nicotinamide on experimental induced diabetes.
    Iranian journal of allergy, asthma, and immunology, 2009, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Insulin;

2009
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Lin

2009
The soluble nickel component of residual oil fly ash alters pulmonary host defense in rats.
    Journal of immunotoxicology, 2009, Volume: 6, Issue:1

    Topics: Air Pollutants; Alum Compounds; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Carbon; Chloride

2009
Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide.
    Behavioural brain research, 2010, Jan-05, Volume: 206, Issue:1

    Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Catalase; Corpus Striatum; Disease Models,

2010
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity.
    Life sciences, 2009, Nov-04, Volume: 85, Issue:19-20

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carotenoids; Catalase; Coloring Agents; Electron Tran

2009
Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats.
    Steroids, 2010, Volume: 75, Issue:11

    Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Chemokine CCL2; Choles

2010
Daily reoxygenation decreases myocardial injury and improves post-ischaemic recovery after chronic hypoxia.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2010, Volume: 37, Issue:4

    Topics: Animals; Body Weight; Chronic Disease; Hematocrit; Hemoglobins; Hypoxia; Male; Myocardial Infarction

2010
Genetic effects analysis of myeloid leukemia factor 2 and T cell receptor-beta on resistance to coccidiosis in chickens.
    Poultry science, 2010, Volume: 89, Issue:1

    Topics: Animals; Body Weight; Carotenoids; Chickens; Coccidiosis; Female; Genetic Markers; Genetic Predispos

2010
Upregulation of arginase expression and activity in hypertensive rats exposed to chronic intermittent hypobaric hypoxia.
    High altitude medicine & biology, 2009,Winter, Volume: 10, Issue:4

    Topics: Acclimatization; Altitude; Animals; Arginase; Atmospheric Pressure; Blood Pressure; Body Weight; Hea

2009
Anti-ulcer role of herbomineral Siddha drug - Thamira parpam on experimentally induced gastric mucosal damage in rats.
    Human & experimental toxicology, 2010, Volume: 29, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Body Weight; Cytoprotection; Disease Models, Anim

2010
Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:5

    Topics: Animals; Arginase; Blotting, Western; Body Weight; Chronic Disease; Dual Specificity Phosphatase 1;

2010
Gastroprotective effect of Saccharomyces boulardii in a rat model of ibuprofen-induced gastric ulcer.
    Pharmacology, 2010, Volume: 85, Issue:3

    Topics: Animals; Body Weight; Cytoprotection; Disease Models, Animal; Gastric Mucosa; Ibuprofen; Male; Nitra

2010
Comparative neuroprotective profile of statins in quinolinic acid induced neurotoxicity in rats.
    Behavioural brain research, 2011, Jan-01, Volume: 216, Issue:1

    Topics: Analysis of Variance; Animals; Atorvastatin; Behavior, Animal; Body Weight; Corpus Striatum; Fatty A

2011
Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.
    Neuroscience, 2010, Nov-24, Volume: 171, Issue:1

    Topics: Acetates; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Cata

2010
Attenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats.
    Brain research, 2011, Feb-04, Volume: 1372

    Topics: Analysis of Variance; Animals; Apoptosis; Body Weight; Calcium Channel Blockers; Catalase; Cytokines

2011
Olprinone, a specific phosphodiesterase (PDE)-III inhibitor, reduces the development of multiple organ dysfunction syndrome in mice.
    Pharmacological research, 2011, Volume: 64, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Amylases; Animals; Apoptosis; Ascitic Fluid; Aspartate A

2011
Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response.
    Journal of pineal research, 2011, Volume: 50, Issue:3

    Topics: Animals; Animals, Newborn; Body Weight; Cell Line; Cells, Cultured; Estrogens; Female; Interleukin-6

2011
Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes.
    International journal of obesity (2005), 2011, Volume: 35, Issue:12

    Topics: Adipocytes; Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Coculture Techniques; Diet, H

2011
Investigation of the potential effects of metformin on atherothrombotic risk factors in hyperlipidemic rats.
    European journal of pharmacology, 2011, Jun-01, Volume: 659, Issue:2-3

    Topics: Animals; Antioxidants; Aorta; Atherosclerosis; Blood Coagulation; Body Weight; Carotid Arteries; Cho

2011
Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats.
    Molecular and cellular biochemistry, 2011, Volume: 354, Issue:1-2

    Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Body Weight; Caveolin 1; Cholesterol; Collage

2011
Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone.
    British journal of pharmacology, 2011, Volume: 164, Issue:2b

    Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Body Weight; Caspase 3; Corpus Striatum; Dinopro

2011
Involvement of nitric oxide in corticosterone release and glucose metabolism in food deprived rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2011, Volume: 43, Issue:6

    Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Food Deprivation; Glycogen; Glycogen Phosphoryl

2011
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
    Behavioural brain research, 2011, Oct-31, Volume: 224, Issue:2

    Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental;

2011
A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Antioxidants; Blueberry Plants; Body Weight; Catalase; Creatinine; Diet; Glutathione; Horme

2011
Oleanolic acid prevents glucocorticoid-induced hypertension in rats.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:10

    Topics: Animals; Blood Pressure; Body Weight; Dexamethasone; Glucocorticoids; Heart; Hypertension; Lipid Per

2011
Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms.
    European journal of pharmacology, 2012, Jan-05, Volume: 674, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Catalase; Cytokines; Extremities; Fenofibrate; Glutat

2012
Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity.
    European journal of pharmacology, 2012, Jan-15, Volume: 674, Issue:2-3

    Topics: Amines; Animals; Body Weight; Brain; Catalase; Cyclohexanecarboxylic Acids; GABAergic Neurons; Gabap

2012
Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats.
    European journal of pharmacology, 2012, Mar-15, Volume: 679, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Aorta; Ascorbic Acid; Blood Pressure; Body Weight; Desoxycorticost

2012
Targeting neuro-inflammatory cytokines and oxidative stress by minocycline attenuates quinolinic-acid-induced Huntington's disease-like symptoms in rats.
    Neurotoxicity research, 2012, Volume: 22, Issue:4

    Topics: Analysis of Variance; Animals; Body Weight; Catalase; Cytokines; Disease Models, Animal; Dose-Respon

2012
[Study on acute and subchronic toxicity of ammonium dinitramide].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:11

    Topics: Animals; Body Weight; Female; Liver; Male; Mice; Mice, Inbred Strains; Nitrites; Quaternary Ammonium

2011
Quercetin intake during lactation modulates the AMP-activated protein kinase pathway in the livers of adult male rat offspring programmed by maternal protein restriction.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Acetyl-CoA Carboxylase; Age Factors; AMP-Activated Protein Kinases; Animals; Body Weight; Diet, Prot

2013
Oxidative stress programming in a rat model of postnatal early overnutrition--role of insulin resistance.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Catalase; Eating; Female; Glutathione Peroxidase; Insulin; I

2013
Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium; Cyclic GMP; Disulfide

2012
The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester in rats with sub-acute peritonitis.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Acute Disease; Animals; Arginine; Body Weight; Cell Proliferation; Cytokines; Dose-Response Relation

2012
Iron increases liver injury through oxidative/nitrative stress in diabetic rats: Involvement of nitrotyrosination of glucokinase.
    Biochimie, 2012, Volume: 94, Issue:12

    Topics: Animals; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Glucokinase; Iron; Iron Overload

2012
Region-specific changes in activities of cell death-related proteases and nitric oxide metabolism in rat brain in a chronic unpredictable stress model.
    Metabolic brain disease, 2012, Volume: 27, Issue:4

    Topics: Animals; Body Weight; Brain Chemistry; Calpain; Caspase 3; Cathepsin B; Cell Count; Cell Death; Cort

2012
Protective effect of 2-hydroxy-4-methoxy benzoic acid on testosterone induced benign prostatic hyperplasia in Wister rats.
    European journal of pharmacology, 2013, Jan-05, Volume: 698, Issue:1-3

    Topics: Animals; Benzoates; Body Weight; Catalase; Epithelium; Glutathione; Lipid Peroxides; Male; Nitrites;

2013
The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain.
    European journal of pharmacology, 2013, Jan-30, Volume: 700, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Body Weight; Brain; Cytokines; Diabetes Mellitus, Typ

2013
Effects of Cudrania tricuspidata water extract on blood pressure and renal functions in NO-dependent hypertension.
    Life sciences, 2002, Apr-19, Volume: 70, Issue:22

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Blotting, Western; Body Weight; C

2002
Angiotensinogen gene knockout delays and attenuates cold-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:2

    Topics: Angiotensinogen; Animals; Blood Pressure; Body Weight; Brain; Cold Temperature; Female; Gene Express

2003
Inflammatory liver steatosis caused by IL-12 and IL-18.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2003, Volume: 23, Issue:3

    Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Body Weight; Dose-Response Relatio

2003
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.
    The American journal of pathology, 2003, Volume: 162, Issue:6

    Topics: Animals; Blood-Retinal Barrier; Body Weight; Diabetes Mellitus, Experimental; Endothelial Growth Fac

2003
NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis.
    Kidney international, 2003, Volume: 64, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Body Weight; Enzyme Inhibitors; Fibronectins; Fibrosis; Gene Expr

2003
Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:3

    Topics: 3-Hydroxybutyric Acid; Alloxan; Animals; Blood Glucose; Blood Pressure; Body Weight; Carbon Dioxide;

2003
Effects of dietary nitrite on the chick: growth, liver vitamin A stores and thyroid weight.
    The Journal of nutrition, 1963, Volume: 79, Issue:2

    Topics: Animals; Body Weight; Chickens; Diet; Humans; Liver; Nitrites; Thyroid Gland; Vitamin A

1963
THE INFLUENCE OF METHEMOGLOBINEMIA ON THE LETHALITY OF SOME TOXIC ANIONS. I. AZIDE.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Animals; Anions; Azides; Body Weight; Borates; Cyanates; Fluorides; Methemoglobinemia; Mice; Nitrite

1964
THE INFLUENCE OF METHEMOGLOBINEMIA ON THE LETHALITY OF SOME TOXIC ANIONS. II. SULFIDE.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Animals; Anions; Body Weight; Methemoglobinemia; Mice; Nitrites; Propiophenones; Propylene Glycols;

1964
Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation.
    The Journal of physiology, 2004, Jun-01, Volume: 557, Issue:Pt 2

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Body Weigh

2004
Effects of sesame oil on oxidative stress and hepatic injury after cecal ligation and puncture in rats.
    Shock (Augusta, Ga.), 2004, Volume: 21, Issue:5

    Topics: Animals; Anions; Body Weight; Cecum; Hydroxyl Radical; Lipid Peroxidation; Liver; Mineral Oil; Nitri

2004
TP receptors regulate renal hemodynamics during angiotensin II slow pressor response.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Rece

2004
Perinatal salt restriction: a new pathway to programming insulin resistance and dyslipidemia in adult wistar rats.
    Pediatric research, 2004, Volume: 56, Issue:6

    Topics: Age Factors; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Female; Hyperlipidemias;

2004
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experiment

2005
Orally administrated aluminum-maltolate complex enhances oxidative stress in the organs of mice.
    Journal of inorganic biochemistry, 2004, Volume: 98, Issue:12

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Body Weight; Brain; Immunohistochemistry; Kid

2004
The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia.
    International journal of tissue reactions, 2004, Volume: 26, Issue:1-2

    Topics: Amino Acids; Animals; Body Weight; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Disease

2004
Exercise improves biomarkers of health and stress in animals fed ad libitum.
    Physiology & behavior, 2005, Jan-31, Volume: 84, Issue:1

    Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Biomarkers; Blood Glucose; Body Mass I

2005
Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity.
    Free radical biology & medicine, 2005, Mar-15, Volume: 38, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animal Feed; Animals; Antioxidants; Astrocytes; Blotti

2005
Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment.
    Journal of the Society for Gynecologic Investigation, 2005, Volume: 12, Issue:3

    Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Electrolytes; E

2005
Effects of chronic quercetin treatment in experimental renovascular hypertension.
    Molecular and cellular biochemistry, 2005, Volume: 270, Issue:1-2

    Topics: Animals; Antioxidants; Aorta; Blood Pressure; Body Weight; Diet; Disease Models, Animal; Dose-Respon

2005
Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats.
    Free radical biology & medicine, 2005, Jul-01, Volume: 39, Issue:1

    Topics: Animals; Aorta, Thoracic; Body Weight; Cyclic N-Oxides; Enzyme Induction; Estradiol; Female; Glutath

2005
Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats.
    Receptors & channels, 2004, Volume: 10, Issue:5-6

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Body Weight; C

2004
Modulatory role of green tea extract on antinociceptive effect of morphine in diabetic mice.
    Journal of medicinal food, 2005,Fall, Volume: 8, Issue:3

    Topics: Analgesics; Animals; Arginine; Blood Glucose; Body Weight; Camellia sinensis; Diabetes Mellitus, Exp

2005
Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat.
    Kidney & blood pressure research, 2005, Volume: 28, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartate Aminotransferases; Blood Pressure; Body

2005
Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin.
    Kidney international, 2005, Volume: 68, Issue:6

    Topics: Animals; Body Weight; Calmodulin; Caveolin 1; Down-Regulation; Guanylate Cyclase; Immunohistochemist

2005
Possible role of nitric oxide in the protective effect of resveratrol in 5/6th nephrectomized rats.
    The Journal of surgical research, 2006, Jun-15, Volume: 133, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Pressure; Body Weight; Disease Models, Animal; Eat

2006
Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun.
    Cancer research, 2006, Mar-01, Volume: 66, Issue:5

    Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; Diet; Dimethylnitrosa

2006
Inactivation of Kupffer cells by gadolinium administration prevents lipopolysaccharide-induced decrease in liver insulin-like growth factor-I and IGF-binding protein-3 gene expression.
    The Journal of endocrinology, 2006, Volume: 188, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Blotting, Northern; Blotting, Western; Body Weight; Cell Survi

2006
Repeated thermal therapy up-regulates endothelial nitric oxide synthase and augments angiogenesis in a mouse model of hindlimb ischemia.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:4

    Topics: Animals; Apolipoproteins E; Blood Pressure; Blotting, Western; Body Weight; Female; Heart Rate; Hind

2006
Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain.
    European journal of pharmacology, 2006, May-01, Volume: 536, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Brain; Cur

2006
Vasopressin and nitric oxide synthesis after three days of water or food deprivation.
    Acta biologica Hungarica, 2006, Volume: 57, Issue:1

    Topics: Animals; Body Weight; Enzyme Activation; Food Deprivation; Hematocrit; Homeostasis; Male; Nitrates;

2006
Stocking density and physiological adaptive responses of broilers.
    Poultry science, 2006, Volume: 85, Issue:5

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Chickens; Cholesterol; Corticosteron

2006
Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:5

    Topics: Analysis of Variance; Animals; Atorvastatin; Biomarkers; Blood Pressure; Body Weight; Dexamethasone;

2006
Increased extravasation of macromolecules in skeletal muscles of the Zucker rat model.
    Obesity (Silver Spring, Md.), 2006, Volume: 14, Issue:5

    Topics: Albumins; Animals; Blood Glucose; Body Weight; Capillary Permeability; Disease Models, Animal; Evans

2006
Influence of physical preconditioning on the responsiveness of rat pulmonary artery after pulmonary ischemia/reperfusion.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 147, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Lung; Nitrates; Nitrites; Ph

2007
Effect of sex hormones on non-esterified fatty acids, intra-abdominal fat accumulation, and hypertension induced by sucrose diet in male rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:8

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Dietary Sucrose; Disease Models, Animal; Estrad

2006
Reactivity of mesenteric and aortic rings from trained rats fed with high caloric diet.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 147, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Diet; Dose-Response Relat

2007
beta1 antagonist and beta2 agonist, celiprolol, restores the impaired endothelial dependent and independent responses and decreased TNFalpha in rat with type II diabetes.
    Life sciences, 2007, Jan-16, Volume: 80, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Animals; Aorta, Abdomin

2007
Nitric oxide modulates glutathione synthesis during endotoxemia.
    Free radical biology & medicine, 2006, Dec-15, Volume: 41, Issue:12

    Topics: Animals; Body Weight; Catalase; Cysteine; Disease Models, Animal; Eating; Endotoxemia; Glutamate-Cys

2006
Enhancing engraftment of islets using perioperative sodium 4-phenylbutyrate.
    International immunopharmacology, 2006, Dec-20, Volume: 6, Issue:13-14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Diabetes Mellitus, Exp

2006
Nitric oxide modulates gonadal and adrenal function in Japanese quail Coturnix coturnix japonica.
    General and comparative endocrinology, 2007, May-01, Volume: 151, Issue:3

    Topics: Adrenal Glands; Animals; Body Weight; Cloaca; Coturnix; Gonads; Hypothalamus; Male; NG-Nitroarginine

2007
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
    Experimental neurology, 2007, Volume: 205, Issue:2

    Topics: Anesthesia; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies;

2007
A moderately high fat diet promotes salt-sensitive hypertension in obese zucker rats by impairing nitric oxide production.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2007, Volume: 29, Issue:6

    Topics: Animals; Body Weight; Diet; Dietary Fats; Disease Models, Animal; Feedback, Physiological; Female; H

2007
Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Body Weight; Chemokine CCL2; Dinoprost; Disease Models, Animal; Eating; Free Radical Scaven

2008
Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2007, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Anaerobic Threshold; Antioxidants; Ascorbic Acid; Body Composition; Body Weight;

2007
Methotrexate-induced nitrosative stress may play a critical role in small intestinal damage in the rat.
    Archives of toxicology, 2008, Volume: 82, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Duodenum; Ileum; Immunohistochemistry; Inject

2008
Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy.
    Nitric oxide : biology and chemistry, 2008, Volume: 18, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Arginine; bcl-2-Associated X Protein; Body Weight; Caspase 3;

2008
Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice.
    Neuroscience research, 2008, Volume: 60, Issue:4

    Topics: Alprazolam; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Behavioral Symptoms; Body Weig

2008
Possible involvement of Akt activity in endothelial dysfunction in type 2 diabetic mice.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clonidine;

2008
Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice.
    Diabetologia, 2008, Volume: 51, Issue:7

    Topics: Adipose Tissue; Animals; Antioxidants; Aorta; Body Weight; Diabetes Mellitus, Type 2; Diabetic Angio

2008
Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats.
    The Chinese journal of physiology, 2007, Dec-31, Volume: 50, Issue:6

    Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Endothelin-1; Enzyme Inhibitors; Glomerul

2007
Effects of dietary nitrite and nitrate on experimentally-induced inflammation in the rat.
    International journal of tissue reactions, 1983, Volume: 5, Issue:2

    Topics: Animals; Body Weight; Collagen; Diet; Glycosaminoglycans; Granuloma; Inflammation; Nitrates; Nitrite

1983
Effects of biotin, with or without sodium nitrite, on weight, food and fluid intake, and on methemoglobin, lactate and lipids in the blood of rats.
    Artery, 1980, Volume: 7, Issue:3

    Topics: Animals; Biotin; Body Weight; Diet; Lactates; Linoleic Acids; Lipids; Male; Methemoglobinemia; Mice;

1980
Developmental toxicity and psychotoxicity of sodium nitrite in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Body Weight; Female; Growth; Male; Nitrites; Rats; Rats, Inbred St

1984
Nutrient intake and health status of lactovegetarians: chemical analyses of diets using the duplicate portion sampling technique.
    The American journal of clinical nutrition, 1984, Volume: 40, Issue:2

    Topics: Animals; Body Weight; Diet, Vegetarian; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energ

1984
The toxicity of the daily intake of nitrite and dimethylamine.
    Die Nahrung, 1983, Volume: 27, Issue:9

    Topics: Alanine Transaminase; Animals; Body Weight; Dimethylamines; Dose-Response Relationship, Drug; Kidney

1983
Nitrite toxicity to fathead minnows: effect of fish weight.
    Bulletin of environmental contamination and toxicology, 1984, Volume: 32, Issue:2

    Topics: Animals; Body Weight; Carps; Cyprinidae; Nitrites

1984
[Effect of simultaneous administration of sodium nitrate and sodium nitrite on carbaryl toxicity in long-term study].
    Roczniki Panstwowego Zakladu Higieny, 1982, Volume: 33, Issue:3

    Topics: Animals; Body Weight; Carbaryl; Male; Nitrates; Nitrites; Organ Size; Rats; Rats, Inbred Strains; So

1982
[Experience in pair-feeding of rats treated with nitrate or sodium nitrite].
    Annals of nutrition & metabolism, 1983, Volume: 27, Issue:1

    Topics: Animals; Body Weight; Diuresis; Drinking; Eating; Male; Nitrates; Nitrites; Proteins; Rats; Rats, In

1983
Study of the carcinogenicity of large doses of dimethylnitramine, N-nitroso-L-proline, and sodium nitrite administered in drinking water to rats.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:6

    Topics: Animals; Body Weight; Carcinogens; Dimethylamines; Dose-Response Relationship, Drug; Female; Lethal

1980
Effect of dietary ascorbic acid on the susceptibility of steelhead trout (Salmo gairdneri) to nitrite toxicity.
    Revista de biologia tropical, 1980, Volume: 28, Issue:1

    Topics: Animal Feed; Animals; Ascorbic Acid; Body Weight; Methemoglobin; Methemoglobinemia; Nitrites; Salmon

1980
[Nitrates and nitrates: nutritional impacts in the rat (author's transl)].
    Annals of nutrition & metabolism, 1981, Volume: 25, Issue:3

    Topics: Anemia; Animals; Blood Cell Count; Body Weight; Dose-Response Relationship, Drug; Hematocrit; Hemogl

1981
Polymicrobial sepsis following trauma inhibits interleukin-10 secretion and lymphocyte proliferation.
    The Journal of trauma, 1995, Volume: 39, Issue:1

    Topics: Animals; Body Weight; Cell Division; Concanavalin A; Immunity, Cellular; Interleukin-10; Lipopolysac

1995
Antihypertensive effect of oral nitrite uptake in the spontaneously hypertensive rat.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:3

    Topics: Adult; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Chromatography, High Pressure

1995
L-arginine may mediate the therapeutic effects of low protein diets.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, May-09, Volume: 92, Issue:10

    Topics: Animals; Arginine; Blood Pressure; Body Weight; Diet, Protein-Restricted; Dietary Proteins; Gene Exp

1995
Local versus systemic immunotoxicity of isobutyl nitrite following subchronic inhalation exposure of female B6C3F1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:2

    Topics: Administration, Inhalation; Animals; Antibody Formation; Blood Bactericidal Activity; Body Weight; F

1995
Bystander injury of host lymphoid tissue during murine graft-verus-host disease is mediated by nitric oxide.
    Transplantation, 1996, Feb-27, Volume: 61, Issue:4

    Topics: Animals; Body Weight; Cell Transplantation; Cytotoxicity, Immunologic; Enzyme Inhibitors; Female; Gr

1996
Dietary nitrite and scavenger antioxidants trace elements.
    International journal of food sciences and nutrition, 1996, Volume: 47, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Mass Index; Body Weight; Cholesterol; Diet

1996
Magnesium deficiency in rats induces a rise in plasma nitric oxide.
    Magnesium research, 1995, Volume: 8, Issue:3

    Topics: Animals; Body Weight; Brain; Diet; Enzyme Induction; In Vitro Techniques; Lipopolysaccharides; Lung;

1995
Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 1

    Topics: Absorptiometry, Photon; Aging; Animals; Blood Pressure; Body Weight; Bone and Bones; Bone Density; E

1996
Effects of cyclosporine or FK506 in chronic colitis.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Colitis; Colon; Cyclosporine; Female; Granulomatous Disease, C

1997
Nitric oxide production during Eimeria tenella infections in chickens.
    Poultry science, 1997, Volume: 76, Issue:6

    Topics: Animals; Body Weight; Cecum; Chickens; Coccidiosis; Eimeria tenella; Endothelium, Vascular; Enzyme I

1997
Enhancement of humoral and cellular immunity by vitamin E after embryonic exposure.
    Poultry science, 1997, Volume: 76, Issue:7

    Topics: Animals; Antibody Formation; Body Weight; Bursa of Fabricius; Cells, Cultured; Chick Embryo; Chicken

1997
Effects of estrogen on atherosclerosis formation and serum nitrite/nitrate concentrations in cholesterol-fed ovariectomized rabbits.
    Journal of atherosclerosis and thrombosis, 1996, Volume: 3, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol; Coronary Artery Disease;

1996
Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Aging; Animals; Arginine; Body Weight; Cell Movement; Diet; Hemodynamics; Kidney; Kidney Glomerulus;

1997
Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous NIDDM.
    Diabetes, 1998, Volume: 47, Issue:1

    Topics: Abdomen; Adipose Tissue; Animals; Blood Glucose; Body Composition; Body Weight; Cholesterol; Diabete

1998
Effects of nitric oxide synthase inhibition or sulfasalazine on the spontaneous colitis observed in HLA-B27 transgenic rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:2

    Topics: Animals; Animals, Genetically Modified; Body Weight; Colitis; Colon; Enzyme Inhibitors; HLA-B27 Anti

1998
Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:3 Pt 1

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Body Weight; Bronchoalveolar Lavage Fluid;

1998
Protective effects of Mu-Fang-Ji-Tang against myocardial injury in a murine model of congestive heart failure induced by viral myocarditis.
    Life sciences, 1998, Volume: 62, Issue:13

    Topics: Animals; Body Weight; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Heart Failure; Macro

1998
Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:6

    Topics: Age Factors; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Body Weight; Creatinine; Data In

1998
Aminoguanidine reduces glomerular inducible nitric oxide synthase (iNOS) and transforming growth factor-beta 1 (TGF-beta1) mRNA expression and diminishes glomerulosclerosis in NZB/W F1 mice.
    Clinical and experimental immunology, 1998, Volume: 113, Issue:2

    Topics: Animals; Body Weight; Cell Count; Creatine; Crosses, Genetic; Enzyme Inhibitors; Female; Guanidines;

1998
Impairment of nitric oxide-mediated relaxations in anaesthetized autoperfused streptozotocin-induced diabetic rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:5

    Topics: Acetylcholine; Anesthesia; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes M

1998
The cytochrome P450 suicide inhibitor, 1-aminobenzotriazole, sensitizes rats to zymosan-induced toxicity.
    Research communications in molecular pathology and pharmacology, 1998, Volume: 102, Issue:1

    Topics: Animals; Body Weight; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Inflamm

1998
Alteration of Kupffer cell function and morphology by low melt point paraffin wax in female Fischer-344 but not Sprague-Dawley rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 46, Issue:1

    Topics: Animals; Body Weight; Enzymes; Female; Kupffer Cells; Leukocyte Count; Leukotriene B4; Liver; Nitrit

1998
Long-term vascular effects of Nomega-nitro-L-arginine methyl ester are not soley mediated by inhibition of endothelial nitric oxide synthesis in the rat mesenteric artery.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:4

    Topics: Animals; Blood Pressure; Body Weight; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Male; Me

1999
A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA.
    Biochemical and biophysical research communications, 1999, Jun-07, Volume: 259, Issue:2

    Topics: Acyl Coenzyme A; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Endothelium, V

1999
Altered pressure-natriuresis in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Diuresis; Glomerular Filtration Rate; Insulin;

1999
Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli.
    Diabetologia, 1999, Volume: 42, Issue:7

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructosamin

1999
Low temperature hemodialysis prevents hypote nsive episodes by reducingnitric oxide synthesis.
    Nephron, 2000, Volume: 84, Issue:3

    Topics: Aged; Body Weight; Female; Humans; Hypotension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites;

2000
Biphasic changes in nitric oxide generation in hemodialyzed patients with end-stage renal disease treated with recombinant human erythropoietin.
    The American journal of the medical sciences, 2000, Volume: 319, Issue:3

    Topics: Blood Pressure; Body Weight; Erythropoietin; Female; Heart Rate; Humans; Kidney Failure, Chronic; Ma

2000
Effects of angiotensin II type 1 receptor antagonist on nitric oxide synthase expression and myocardial remodeling in Goldblatt hypertensive rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Bo

2000
Antioxidant enzyme activities and total nitrite/nitrate levels in the collar model. Effect of nicardipine.
    Clinical chemistry and laboratory medicine, 2000, Volume: 38, Issue:1

    Topics: Animals; Antioxidants; Body Weight; Calcium Channel Blockers; Carotid Arteries; Catalase; Cholestero

2000
Erythropoietin does not affect nitric oxide system in rats with chronic renal failure.
    Journal of Korean medical science, 2000, Volume: 15, Issue:2

    Topics: Acetylcholine; Anemia; Animals; Aorta, Thoracic; Body Weight; Erythropoietin; Hypertension, Renal; I

2000
Analysis of disease resistance-associated parameters in broiler chickens challenged with Eimeria maxima.
    Poultry science, 2000, Volume: 79, Issue:5

    Topics: Animals; Body Weight; Carotenoids; Chickens; Coccidiosis; Eimeria; Enzyme-Linked Immunosorbent Assay

2000
Aldehyde induced hypertension in rats: prevention by N-acetyl cysteine.
    Artery, 1998, Volume: 23, Issue:1

    Topics: Acetylcysteine; Aldehydes; Animals; Arterioles; Blood Platelets; Blood Pressure; Body Weight; Calciu

1998
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; B

2000
Preservation of the antioxidant status in chemically-induced diabetes mellitus by melatonin.
    Journal of pineal research, 2000, Volume: 29, Issue:2

    Topics: Administration, Oral; Alloxan; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes

2000
Endothelin regulates angiotensin-converting enzyme in the mouse kidney.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Animals; Body Weight; Dietary Fats; Endothelin-1; Kidney; Lipids; Male; Mice; Mice, Inbred C57BL; Ni

2000
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation;

2000
Age-related alterations of nitric oxide production in the brains of seizure-susceptible EL mice.
    Brain research bulletin, 2000, Volume: 53, Issue:3

    Topics: Aging; Animals; Body Weight; Brain; Cell Count; Cerebral Cortex; Corpus Striatum; Hippocampus; Mice;

2000
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:12

    Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Dis

2000
Altered endothelium-dependent responsiveness in the aortas and renal arteries of Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of non-insulin-dependent diabetes mellitus.
    General pharmacology, 2000, Volume: 34, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Biological Factors; Blood Glucose; Body Weight; Cardiovascular Agents

2000
The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat.
    Journal of hypertension, 2000, Volume: 18, Issue:12

    Topics: Adrenocorticotropic Hormone; Animals; Arginine; Blood Pressure; Body Weight; Corticosterone; Drinkin

2000
Increased nitric oxide is one of the causes of changes of iron metabolism in strenuously exercised rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: Animals; Body Weight; Bone Marrow; Enzyme Inhibitors; Female; Iron; Liver; NG-Nitroarginine Methyl E

2001
Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats.
    Archives of physiology and biochemistry, 2000, Volume: 108, Issue:5

    Topics: Acetylcholine; Administration, Oral; Animals; Arginine; Blood Pressure; Body Weight; Epoprostenol; H

2000
Disturbance of circadian rhythm in heart rate, blood pressure and locomotive activity at the stroke-onset in malignant stroke-prone spontaneously hypertensive rats.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Circadian Rhythm; Drinking Behavior; Heart Rate; Motor Activit

2001
Oral estrogen replacement therapy increases forearm reactive hyperemia accompanied by increases in serum levels of nitric oxide in postmenopausal women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2001, Volume: 15, Issue:2

    Topics: Body Weight; Endothelium, Vascular; Estrogen Replacement Therapy; Female; Forearm; Heart Rate; Human

2001
Long-term effect of bilateral ovariectomy on endothelial function in aortic rings of spontaneously hypertensive rats: role of nitric oxide.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2001, Volume: 15, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Body Weight; Endothelium, Vascular; Enzyme Inhibitors

2001
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Body Weight; Disease Models, Animal; Glucose;

2001
Space experiment using large-sized fish: in case of carp in Spacelab-J mission.
    Acta astronautica, 1994, Volume: 33

    Topics: Animals; Body Weight; Carps; Equipment Design; Housing, Animal; Life Support Systems; Light; Motor A

1994
Water quality management for low temperature marine fishes in space.
    Uchu Seibutsu Kagaku, 1999, Volume: 13, Issue:4

    Topics: Animals; Aquaculture; Body Weight; Filtration; Fishes; Hydrogen-Ion Concentration; Life Support Syst

1999
Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.
    British journal of pharmacology, 2001, Volume: 134, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Body Weight; Cyclic GMP; Cyclosporine; Dose-Response R

2001
Effect of age and body weight on neurohumoral variables in healthy Cavalier King Charles spaniels.
    American journal of veterinary research, 2001, Volume: 62, Issue:11

    Topics: Age Factors; Animals; Atrial Natriuretic Factor; Body Weight; Cardiac Output; Creatinine; Cyclic GMP

2001
Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats.
    Pharmacological research, 2001, Volume: 44, Issue:5

    Topics: Animals; Biomarkers; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glycosylat

2001
Chronic diabetic nephropathy: role of inducible nitric oxide synthase.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Chronic Disease; Diabetic Nephropathies; Growth; Immunoblotting

2002
Effects of Choto-san on hemorheological factors and vascular function in stroke-prone spontaneously hypertensive rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:2

    Topics: Acetylcholine; Animals; Blood Pressure; Blood Viscosity; Body Weight; Dose-Response Relationship, Dr

2002
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:6

    Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus,

2002
Effect of exercise on blood pressure in rats with chronic NOS inhibition.
    European journal of applied physiology, 2002, Volume: 87, Issue:2

    Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Body Weight; Chronic Disease; Heart; Hear

2002
High doses of nitrate in rations for milk-fed calves. 1. Effect on zootechnical characteristics, methemoglobin formation and nitrate and nitrite in some organs.
    Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde, 1979, Volume: 42, Issue:6

    Topics: Animal Feed; Animals; Body Weight; Cattle; Hemoglobins; Male; Methemoglobinemia; Milk; Nitrates; Nit

1979
[Effects of sodium nitrite on various vitamin concentrations in rat tissues].
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1978, Volume: 48, Issue:1

    Topics: Animals; Biotin; Body Weight; Male; Nicotinic Acids; Nitrites; Organ Size; Pantothenic Acid; Pyridox

1978
Effect of sodium nitrite, carbon monoxide, and reduced food supply on unilateral ovarian compensatory hypertrophy in the rat.
    Toxicology and applied pharmacology, 1978, Volume: 43, Issue:2

    Topics: Animals; Body Weight; Carbon Monoxide; Castration; Female; Food Deprivation; Hypertrophy; Nitrites;

1978
Effects of imipramine, nitrite, and dimethylnitrosamine on reproduction in mice.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 19, Issue:2

    Topics: Animals; Birth Weight; Body Weight; Dimethylnitrosamine; Drug Interactions; Female; Fertility; Imipr

1978
[Effects of prolonged administration of sodium nitrite on rat's body].
    Roczniki Panstwowego Zakladu Higieny, 1976, Volume: 27, Issue:3

    Topics: Adrenal Glands; Animals; Body Weight; Hemoglobins; Male; Nitrites; Organ Size; Rats; Spleen

1976
Effect of vitamin A on formation, toxicity and carcinogenicity of nitroso-n-methylbenzylamine.
    IARC scientific publications, 1976, Issue:14

    Topics: Amines; Animals; Benzylamines; Body Weight; Carcinogens; Chemical Phenomena; Chemistry; Neoplasms, E

1976
[Nitrates and nitrites and the utilization of beta-carotene. I. The effect of different amounts of dietary nitrates and nitrites on the utilization of beta-carotene in rats].
    Roczniki Panstwowego Zakladu Higieny, 1990, Volume: 41, Issue:3-4

    Topics: Animals; beta Carotene; Body Weight; Carotenoids; Liver; Male; Nitrates; Nitrites; Rats; Rats, Inbre

1990
Nitrate, nitrite, and N-nitroso compounds in Finnish foods and the estimation of the dietary intakes.
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1990, Volume: 190, Issue:4

    Topics: Adolescent; Adult; Beer; Body Weight; Child; Child, Preschool; Eating; Finland; Fish Products; Food

1990
Generation of high yields of Syrian hamster cholangiocellular carcinomas and hepatocellular nodules by combined nitrite and aminopyrine administration and Opisthorchis viverrini infection.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:8

    Topics: Adenoma, Bile Duct; Aminopyrine; Animals; Body Weight; Cricetinae; Liver; Liver Neoplasms; Liver Neo

1988
Acute and chronic toxicity of nitrite to Clarias lazera.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:2

    Topics: Animals; Blood Proteins; Body Weight; Erythrocyte Count; Fishes; Hematocrit; Methemoglobin; Nitrites

1987
Subchronic toxicology of butyl nitrites in mice by inhalation.
    Journal of applied toxicology : JAT, 1985, Volume: 5, Issue:3

    Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Glucose-6-Phosphatase; Isocitrate Dehydrogenas

1985
[Methemoglobinemia in pigs and the effect of nitrites on the health and growth of piglets].
    Veterinarni medicina, 1986, Volume: 31, Issue:3

    Topics: Age Factors; Animal Feed; Animals; Body Weight; Hemoglobins; Methemoglobinemia; Nitrites; Swine; Swi

1986
Toxicity of inhaled isobutyl nitrite in BALB/c mice: systemic and immunotoxic studies.
    NIDA research monograph, 1988, Volume: 83

    Topics: Administration, Inhalation; Animals; Antibody Formation; Antigens, Surface; Body Weight; Female; Imm

1988
Evaluation of the oral toxicity of potassium nitrite in a 13-week drinking-water study in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1988, Volume: 26, Issue:10

    Topics: Administration, Oral; Adrenal Glands; Animals; Blood; Body Weight; Drinking; Female; Kidney; Male; N

1988
Evaluation of the developmental toxicity of sodium nitrite in Long-Evans rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:4

    Topics: Animals; Animals, Newborn; Blood Chemical Analysis; Body Weight; Drinking; Erythrocyte Count; Female

1987
Effects of cimetidine, nitrite, cimetidine plus nitrite, and nitrosocimetidine on tumors in mice following transplacental plus chronic lifetime exposure.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Animals; Body Weight; Cimetidine; Dose-Response Relationship, Drug; Female; Fetus; Lung Neoplasms; M

1985
Subchronic inhalation toxicity of isobutyl nitrite in BALB/c mice. I. Systemic toxicity.
    Journal of toxicology and environmental health, 1985, Volume: 15, Issue:6

    Topics: Animals; Atmosphere Exposure Chambers; Blood; Body Weight; Female; Liver; Lung; Male; Mice; Mice, In

1985
[Rhodanide as a catalyst of nitrosamine synthesis in vivo].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1974, Volume: 227, Issue:1-4

    Topics: Amines; Animals; Benzyl Compounds; Body Weight; Catalysis; Chromatography, Gas; Diethylamines; Gastr

1974
Effect of chronic systemic hypoxia of the methaemoglobin type on the rat myocardium and its resistance to anoxia.
    Physiologia Bohemoslovaca, 1966, Volume: 15, Issue:4

    Topics: Adrenal Glands; Animals; Body Weight; Female; Heart; Hypoxia; In Vitro Techniques; Male; Methemoglob

1966
[Induction of malignant tumors in rats by simultaneous feeding of nitrite and secondary amines].
    Zeitschrift fur Krebsforschung, 1969, Sep-25, Volume: 73, Issue:1

    Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Cystaden

1969
[Formation of carcinogenic nitroso compounds in the stomach of laboratory animals and their significance for man. 2].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:11

    Topics: Acetamides; Amides; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Carcinogens; G

1971
Long-term experiment with canned meat treated with sodium nitrite and glucono-delta-lactone in rats.
    Food and cosmetics toxicology, 1972, Volume: 10, Issue:4

    Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Blood Cell Count; Body Weight; Cattle; Diet;

1972
[Behavior and effects of nitrate and nitrite in the organism. I. Changes of methemoglobine concentration in the organism depending on the way of administration of nitrite (author's transl)].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, praventive Medizin, 1974, Volume: 159, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Catheterization; Cats; Duodenum; Female; Hemoglobinometry; Hemo

1974
Protective effect of ascorbic acid on hepatotoxicity caused by sodium nitrite plus aminopyrine.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:3

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Body Weight; Drug Interactions; Liver; Ma

1973
Nitrite-induced methemoglobinemia in guinea pigs: influence of diets containing beets with varying amounts of nitrate, and the effect of ascorbic acid, and methionine.
    The Journal of nutrition, 1973, Volume: 103, Issue:3

    Topics: Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Body Weight; Dose-Response Relat

1973
Ascorbic acid and chemically induced methemoglobinemias.
    Toxicology and applied pharmacology, 1972, Volume: 21, Issue:2

    Topics: Animals; Ascorbic Acid; Body Weight; Carbon Isotopes; Drug Stability; Guinea Pigs; Hydroxylamines; M

1972
Lactic and succinic dehydrogenase activity in nitrite toxicosis in the guinea pig.
    American journal of veterinary research, 1970, Volume: 31, Issue:2

    Topics: Animals; Appetite Depressants; Body Weight; Guinea Pigs; Hemoglobins; Hyperemia; Hypoxia; Kidney; L-

1970
[Studies on the origin of carcinogenic nitrosamines in the stomach].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:12

    Topics: Aniline Compounds; Animals; Body Weight; Carcinogens; Female; Gastric Mucosa; Hydrogen-Ion Concentra

1968
[Toxicology of isoprophylnitrite--a nitrous acid ether].
    Gigiena truda i professional'nye zabolevaniia, 1966, Volume: 10, Issue:10

    Topics: Animals; Body Weight; Erythrocytes; Hemoglobinometry; Leukocytes; Mice; Nitrites; Rabbits

1966