nitrites has been researched along with Black Fever in 17 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leishmaniasis is a parasitic disease caused by Leishmania protozoa, which presents a large spectrum of clinical manifestations." | 1.72 | Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection. ( Carvalho, AMRS; Coelho, EAF; da Silva, AD; Duarte, MC; Freitas, CS; Glanzmann, N; Lage, DP; Martins, VT; Mendonça, DVC; Menezes-Souza, D; Oliveira-da-Silva, JA; Ribeiro Antinarelli, LM; Soares Coimbra, E; Tavares, GSV, 2022) |
| " The only orally bioavailable drug miltefosine is toxic, whereas liposomal amphotericin B (AmpB) is expensive." | 1.62 | Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice. ( Bhattacharjee, S; Das, A; Das, MC; Ghosh, C; Jawed, JJ; Majumdar, S; Parveen, S; Saha, B, 2021) |
| "Amphotericin B is a well-established pharmacologically approved drug; however, mainly toxicity is a foremost issue with that drug." | 1.62 | Synergic effect of eugenol oleate with amphotericin B augments anti-leishmanial immune response in experimental visceral leishmaniasis in vitro and in vivo. ( Charan Raja, MR; Debnath, J; Jayaraman, A; Kar, A; Mahapatra, SK; Srinivasan, S, 2021) |
| "Visceral leishmaniasis is a life-threatening disease characterized by intense parasitism of the spleen, liver, and bone marrow." | 1.43 | Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages. ( Aragão, MT; Braz, JM; da Silva, ÂM; de Almeida, RP; de Jesus, AR; de Moura, TR; de Oliveira, FA; Santos, LF; Santos, ML; Santos, PL, 2016) |
| "Human visceral leishmaniasis is caused by Leishmania donovani." | 1.35 | Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote. ( Basu, R; Bhaumik, S; Bhaumik, SK; De, T; Naskar, K; Roy, S; Roychoudhury, K; Singh, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Ribeiro Antinarelli, LM | 1 |
| Glanzmann, N | 1 |
| Mendonça, DVC | 1 |
| Lage, DP | 2 |
| Oliveira-da-Silva, JA | 1 |
| Tavares, GSV | 1 |
| Carvalho, AMRS | 1 |
| Freitas, CS | 1 |
| Martins, VT | 2 |
| Duarte, MC | 2 |
| Menezes-Souza, D | 1 |
| da Silva, AD | 1 |
| Coelho, EAF | 1 |
| Soares Coimbra, E | 1 |
| Das, A | 1 |
| Jawed, JJ | 1 |
| Das, MC | 1 |
| Parveen, S | 1 |
| Ghosh, C | 1 |
| Majumdar, S | 2 |
| Saha, B | 1 |
| Bhattacharjee, S | 2 |
| Kar, A | 1 |
| Jayaraman, A | 1 |
| Charan Raja, MR | 1 |
| Srinivasan, S | 1 |
| Debnath, J | 1 |
| Mahapatra, SK | 1 |
| Ibraim, IC | 1 |
| de Assis, RR | 1 |
| Pessoa, NL | 1 |
| Campos, MA | 1 |
| Melo, MN | 1 |
| Turco, SJ | 1 |
| Soares, RP | 1 |
| Chávez-Fumagalli, MA | 1 |
| Garde, E | 1 |
| Costa, LE | 1 |
| da Silva, VG | 1 |
| Silva, VG | 1 |
| Oliveira, JS | 1 |
| Magalhães-Soares, DF | 1 |
| Teixeira, SM | 1 |
| Fernandes, AP | 1 |
| Soto, M | 1 |
| Tavares, CA | 1 |
| Coelho, EA | 1 |
| Leal, JM | 1 |
| Mosquini, M | 1 |
| Covre, LP | 1 |
| Stagmiller, NP | 1 |
| Rodrigues, RR | 1 |
| Christensen, D | 1 |
| de Matos Guedes, HL | 1 |
| Guedes, HL | 1 |
| Rossi-Bergmann, B | 1 |
| Gomes, DC | 1 |
| de Moura, TR | 1 |
| Santos, ML | 1 |
| Braz, JM | 1 |
| Santos, LF | 1 |
| Aragão, MT | 1 |
| de Oliveira, FA | 1 |
| Santos, PL | 1 |
| da Silva, ÂM | 1 |
| de Jesus, AR | 1 |
| de Almeida, RP | 1 |
| Bhardwaj, S | 1 |
| Vasishta, RK | 1 |
| Arora, SK | 1 |
| Datta, S | 1 |
| Adak, R | 1 |
| Chakraborty, P | 1 |
| Haldar, AK | 1 |
| Chakraborty, A | 1 |
| Roy, S | 2 |
| Manna, M | 1 |
| Peruhype-Magalhães, V | 1 |
| Martins-Filho, OA | 1 |
| Prata, A | 1 |
| Silva, Lde A | 1 |
| Rabello, A | 1 |
| Teixeira-Carvalho, A | 1 |
| Figueiredo, RM | 1 |
| Guimarães-Carvalho, SF | 1 |
| Ferrari, TC | 1 |
| Van Weyenbergh, J | 1 |
| Correa-Oliveira, R | 1 |
| Khambu, B | 1 |
| Mehta, KD | 1 |
| Rijal, S | 1 |
| Lamsal, M | 1 |
| Majhi, S | 1 |
| Baral, N | 1 |
| Bhaumik, SK | 1 |
| Singh, M | 1 |
| Basu, R | 1 |
| Bhaumik, S | 1 |
| Roychoudhury, K | 1 |
| Naskar, K | 1 |
| De, T | 1 |
| Jones, LA | 1 |
| Anthony, JP | 1 |
| Henriquez, FL | 1 |
| Lyons, RE | 1 |
| Nickdel, MB | 1 |
| Carter, KC | 1 |
| Alexander, J | 1 |
| Roberts, CW | 1 |
| Bhattacharyya, S | 1 |
| Ghosh, S | 1 |
| Jhonson, PL | 1 |
| Bhattacharya, SK | 1 |
| Das, L | 1 |
| Datta, N | 1 |
| Bandyopadhyay, S | 1 |
| Das, PK | 1 |
| Kumar, R | 1 |
| Pai, K | 1 |
| Sundar, S | 1 |
| Gantt, KR | 1 |
| Goldman, TL | 1 |
| McCormick, ML | 1 |
| Miller, MA | 1 |
| Jeronimo, SM | 1 |
| Nascimento, ET | 1 |
| Britigan, BE | 1 |
| Wilson, ME | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Center, Randomized, Controlled Trial of the Safety and Efficacy of Progesterone for the Treatment of COVID-19 in Hospitalized Men[NCT04365127] | Phase 1 | 40 participants (Actual) | Interventional | 2020-04-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 other studies available for nitrites and Black Fever
| Article | Year |
|---|---|
Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection.
Topics: Animals; Antiprotozoal Agents; Leishmania infantum; Leishmaniasis; Leishmaniasis, Visceral; Mice; Mi | 2022 |
Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cells, Cultured; Cytokines; Drug Synergism; Gene Expr | 2021 |
Synergic effect of eugenol oleate with amphotericin B augments anti-leishmanial immune response in experimental visceral leishmaniasis in vitro and in vivo.
Topics: Amphotericin B; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Synergism; Drug Th | 2021 |
Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cytokines; Female; Gene Expression Regulation; Glycosphi | 2013 |
Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis.
Topics: Animals; Antigens, Protozoan; Cytokines; Dogs; Female; Immunity, Humoral; Leishmania infantum; Leish | 2015 |
Intranasal vaccination with killed Leishmania amazonensis promastigotes antigen (LaAg) associated with CAF01 adjuvant induces partial protection in BALB/c mice challenged with Leishmania (infantum) chagasi.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Protozoan; Antigens, Protoz | 2015 |
Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.
Topics: Adult; Amphotericin B; Animals; Antimony; Cytokines; Drug Resistance; Drug Tolerance; Humans; Immune | 2016 |
Vaccination with a novel recombinant Leishmania antigen plus MPL provides partial protection against L. donovani challenge in experimental model of visceral leishmaniasis.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Antigens, Protozoan; Cricetinae; Cytokines; | 2009 |
Radio-attenuated leishmanial parasites as immunoprophylactic agent against experimental murine visceral leishmaniasis.
Topics: Animals; Cricetinae; Cytokines; Female; Gamma Rays; Humans; Leishmania donovani; Leishmaniasis, Visc | 2012 |
Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-gamma and interleukin-10 and low frequency of tumour necrosis factor-alpha(+) monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania chagas
Topics: Adolescent; Adult; Aged; Cells, Cultured; Child; Child, Preschool; Cytokines; Female; Humans; Immuni | 2006 |
Serum nitrite level and adenosine deaminase activity is altered in visceral leishmaniasis.
Topics: Adenosine Deaminase; Adult; Analysis of Variance; Antimony Sodium Gluconate; Antiprotozoal Agents; F | 2007 |
Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote.
Topics: Agglutination; Animals; Chromatography, Affinity; Clone Cells; Galactosidases; Galactosyltransferase | 2008 |
Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors.
Topics: Animals; Cell Survival; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Down-Regul | 2008 |
Immunomodulatory role of interleukin-10 in visceral leishmaniasis: defective activation of protein kinase C-mediated signal transduction events.
Topics: Adjuvants, Immunologic; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme | 2001 |
Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response.
Topics: Animals; Cells, Cultured; Cystatins; Cysteine Proteinase Inhibitors; Cytokines; Disease Progression; | 2001 |
Reactive oxygen intermediates, nitrite and IFN-gamma in Indian visceral leishmaniasis.
Topics: Adolescent; Adult; Amphotericin B; Female; Follow-Up Studies; Humans; Interferon-gamma; Leishmaniasi | 2001 |
Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; | 2001 |