Page last updated: 2024-10-19

nitrites and Argininosuccinic Aciduria

nitrites has been researched along with Argininosuccinic Aciduria in 1 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Argininosuccinic Aciduria: Rare autosomal recessive disorder of the urea cycle which leads to the accumulation of argininosuccinic acid in body fluids and severe HYPERAMMONEMIA. Clinical features of the neonatal onset of the disorder include poor feeding, vomiting, lethargy, seizures, tachypnea, coma, and death. Later onset results in milder set of clinical features including vomiting, failure to thrive, irritability, behavioral problems, or psychomotor retardation. Mutations in the ARGININOSUCCINATE LYASE gene cause the disorder.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erez, A1
Nagamani, SC1
Shchelochkov, OA1
Premkumar, MH1
Campeau, PM1
Chen, Y1
Garg, HK1
Li, L1
Mian, A1
Bertin, TK1
Black, JO1
Zeng, H1
Tang, Y1
Reddy, AK1
Summar, M1
O'Brien, WE1
Harrison, DG1
Mitch, WE1
Marini, JC1
Aschner, JL1
Bryan, NS1
Lee, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Nitric Oxide (NO) Supplementation on Neurocognitive Measures in Argininosuccinate Lyase Deficiency (ASLD)[NCT03064048]16 participants (Actual)Interventional2017-09-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for nitrites and Argininosuccinic Aciduria

ArticleYear
Requirement of argininosuccinate lyase for systemic nitric oxide production.
    Nature medicine, 2011, Nov-13, Volume: 17, Issue:12

    Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Aciduria; C

2011