Page last updated: 2024-10-19

nitrites and Angiospasm, Intracranial

nitrites has been researched along with Angiospasm, Intracranial in 7 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)."7.70Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000)
"Subacute sodium nitrite infusions prevented delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage."3.73Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. ( Dejam, A; Gladwin, MT; Grimes, G; Oldfield, EH; Pluta, RM, 2005)
"Calcium-elevating protein cross-reacted with anti-human transferrin (TF) was purified in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH)."3.70Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage. ( Kuroda, T; Murase, S; Okumura, A; Sakai, N; Sawada, M; Takenaka, KV, 2000)
"Delayed cerebral vasospasm after subarachnoid hemorrhage (SAH) may be evoked by the decreased availability of nitric oxide (NO)."1.34Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. ( Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M, 2007)
"The pathogenesis of cerebral vasospasm is likely to be multifactorial."1.32Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage. ( Böker, DK; Deinsberger, W; Woszczyk, A, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fathi, AR1
Pluta, RM3
Bakhtian, KD1
Qi, M1
Lonser, RR1
Woszczyk, A1
Deinsberger, W1
Böker, DK1
Dejam, A1
Grimes, G1
Gladwin, MT1
Oldfield, EH2
Jung, CS1
Harvey-White, J1
Espey, MG1
Zimmermann, M1
Seifert, V1
Suzuki, M1
Asahara, H1
Endo, S1
Inada, K1
Doi, M1
Kuroda, K1
Ogawa, A1
Takenaka, KV1
Sakai, N1
Murase, S1
Kuroda, T1
Okumura, A1
Sawada, M1
Sakowitz, OW1
Wolfrum, S1
Sarrafzadeh, AS1
Stover, JF1
Dreier, JP1
Dendorfer, A1
Benndorf, G1
Lanksch, WR1
Unterberg, AW1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2, Multi-Center, Open-label, Randomized, Parallel-Dose Study to Determine the Safety and Efficacy of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension (PAH)[NCT01725256]Phase 229 participants (Actual)Interventional2012-11-30Terminated (stopped due to Terminated early dt to acquisition of Sponsor and change in corporate priorities)
Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453]150 participants (Actual)Observational2021-08-18Active, not recruiting
Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage[NCT05686265]32 participants (Anticipated)Observational2023-05-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for nitrites and Angiospasm, Intracranial

ArticleYear
Reversal of cerebral vasospasm via intravenous sodium nitrite after subarachnoid hemorrhage in primates.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infusions, Intravenous; Macaca fascicularis;

2011
Nitric oxide metabolites in cisternal CSF correlate with cerebral vasospasm in patients with a subarachnoid haemorrhage.
    Acta neurochirurgica, 2003, Volume: 145, Issue:4

    Topics: Adult; Aged; Blood Flow Velocity; Cerebrovascular Circulation; Cisterna Magna; Female; Humans; Intra

2003
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.
    JAMA, 2005, Mar-23, Volume: 293, Issue:12

    Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infarction, Middle Cerebral Artery; Infusions

2005
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; In

2007
Increased levels of nitrite/nitrate in the cerebrospinal fluid of patients with subarachnoid hemorrhage.
    Neurosurgical review, 1999, Volume: 22, Issue:2-3

    Topics: Humans; Nitrates; Nitric Oxide; Nitrites; Reference Values; Subarachnoid Hemorrhage; Vasospasm, Intr

1999
Elevated transferrin concentration in cerebral spinal fluid after subarachnoid hemorrhage.
    Neurological research, 2000, Volume: 22, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Animals; Aorta, Thoracic; Cells, Cultured; Female; Gene Expression R

2000
Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:9

    Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Fe

2001