nitrites has been researched along with Alloxan Diabetes in 155 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac fibrosis was evaluated by Masson trichrome stain." | 5.91 | Impact of atorvastatin on plasma and cardiac biomarkers of inflammation, oxidative stress, and fibrosis in a rat model of streptozotocin-induced diabetes. ( Al Gharram, T; Mayyas, F, 2023) |
| "Changes in vascular endothelial growth factor (VEGF), angiotensin-converting enzyme (ACE), matrix metalloproteinase (MMP)-9, and endothelial nitric oxide synthase (eNOS) mRNA expression profiles and oxidative stress in the eye tissue microenviroment may have important roles in ocular neovascularization and permeability in proliferative diabetic retinopathy." | 3.78 | Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment. ( Alp, E; Aricioglu, A; Cumaoglu, A; Dogan, I; Ekmekci, A; Ergin, V; Menevse, A; Menevse, S; Yar, AS, 2012) |
| "Malondialdehyde (MA) (indicator of LP) in plasma and brain tissue, total nitrite/nitrate (metabolites of nitric oxide) in plasma, nitrite in brain tissue, and SOD in red blood cells were detected and the results were compared before and after VE administration in hyperglycemic rats with cerebral ischemia-reperfusion injury induced by two common carotid artery occlusions." | 3.74 | The effects of vitamin E on lipid peroxidation, nitric oxide production and superoxide dismutase expression in hyperglycemic rats with cerebral ischemia-reperfusion injury. ( Atükeren, P; Gümüştaş, K; Kaynar, MY; Kemerdere, R; Meta Güzeyli, FM; Sanus, GZ; Tanriverdi, T, 2007) |
| "The study has been designed to investigate the effect of demethylasterroquinone B1 (DAQ B1), an activator of Akt, in diabetes mellitus (DM) and hyperhomocysteinemia (HHcy)-induced vascular endothelial dysfunction." | 3.74 | Possible role of Akt to improve vascular endothelial dysfunction in diabetic and hyperhomocysteinemic rats. ( Shah, DI; Singh, M, 2007) |
| "In both rat strains Suramin caused fetal growth retardation, decreased placental blood flow, and increased placental concentration of the isoprostane 8-iso-PGF(2alpha)." | 3.73 | Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment. ( Eriksson, UJ; Nash, P; Olovsson, M, 2005) |
| "Ticlopidine, a thienopyridine that prevents the progression of diabetic retinopathy in humans, was recently shown to increase nitric oxide (NO) production in human neutrophils." | 3.72 | Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. ( Arrebola, M; De La Cruz, P; de la Cuesta, FS; González-Correa, A; Martinez-Cerdán, E; Moreno, A, 2003) |
| "Cardiac fibrosis was evaluated by Masson trichrome stain." | 1.91 | Impact of atorvastatin on plasma and cardiac biomarkers of inflammation, oxidative stress, and fibrosis in a rat model of streptozotocin-induced diabetes. ( Al Gharram, T; Mayyas, F, 2023) |
| "Type 2 diabetes was induced using a low-dose of streptozotocin (25 mg/kg) combined with high-fat diet." | 1.72 | Effect of oral nitrite administration on gene expression of SNARE proteins involved in insulin secretion from pancreatic islets of male type 2 diabetic rats. ( Afzali, H; Ghasemi, A; Jeddi, S, 2022) |
| "Decreased nitric oxide bioavailability in skin contributes to impaired wound healing in type 2 diabetes (T2D)." | 1.56 | Acidified nitrite improves wound healing in type 2 diabetic rats: Role of oxidative stress and inflammation. ( Afzali, H; Ghasemi, A; Jeddi, S; Kashfi, K; Khaksari, M; Norouzirad, R, 2020) |
| "Body weight was measured weekly." | 1.48 | Effect of long-term nitrite administration on browning of white adipose tissue in type 2 diabetic rats: A stereological study. ( Abdollahifar, MA; Ghasemi, A; Haeri Rohani, SA; Jeddi, S; Piryaei, A; Varzandi, T; Zadeh-Vakili, A, 2018) |
| "Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type 2 diabetes." | 1.46 | Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats. ( Bakhtiarzadeh, F; Farrokhfall, K; Ghasemi, A; Gheibi, S; Jeddi, S; Zardooz, H, 2017) |
| "Thalidomide treatment prevented hyperglycemia and preserved pancreatic insulin secretion in the diabetic mice." | 1.38 | Thalidomide attenuates multiple low-dose streptozotocin-induced diabetes in mice by inhibition of proinflammatory cytokines. ( Amirshahrokhi, K; Ghazi-Khansari, M, 2012) |
| "Thermal hyperalgesia and mechanical allodynia were measured using planter test and dynamic aesthesiometer (Ugo-Basile, Italy), respectively." | 1.38 | Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats. ( Sharma, PL; Taliyan, R, 2012) |
| "These results suggest that KPE, acutely in vitro or after 4 weeks administration in vivo, reduces oxidant stress, increases NO bioavailability and preserves endothelium-dependent relaxation in aortae from diabetic rats." | 1.37 | Effects of Kaempferia parviflora Wall. Ex Baker on endothelial dysfunction in streptozotocin-induced diabetic rats. ( Ingkaninan, K; Malakul, W; Sawasdee, P; Thirawarapan, S, 2011) |
| "Vascular dementia is the second leading cause of dementia, which is strongly associated with diabetes." | 1.37 | Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats. ( Sharma, B; Singh, N, 2011) |
| "Diabetic neuropathic pain is amongst the most difficult types of pain to treat mainly due to the lack of understanding of its etiology and inadequate relief with available drug therapy." | 1.37 | Emblica officinalis corrects functional, biochemical and molecular deficits in experimental diabetic neuropathy by targeting the oxido-nitrosative stress mediated inflammatory cascade. ( Chopra, K; Kuhad, A; Tiwari, V, 2011) |
| "Treatment with sodium nitrite (NO donor), L: -arginine (NO precursor), daidzein (caveolin inhibitor), and combination of L: -arginine and daidzein for 2 weeks markedly attenuated these changes and increased serum nitrite/nitrate ratio." | 1.37 | Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats. ( Arya, A; Sharma, PL; Yadav, HN, 2011) |
| "Impaired wound healing in diabetes is associated with decreased nitric oxide (NO) bioavailability in wound tissue." | 1.37 | Azelnidipine, a new calcium channel blocker, promotes skin wound healing in diabetic rats. ( Amirghofran, Z; Bagheri, M; Jahromi, BM; Mirkhani, H; Noorafshan, A; Solhjou, Z; Zamani, A, 2011) |
| "Pravastatin sodium was gavaged at 0." | 1.36 | Effect of pravastatin on experimental diabetic wound healing. ( Bouchier-Hayes, D; Chan, F; Hanson, R; Laing, T, 2010) |
| "Oral treatment with losartan reduces iNOS expression and reestablishes the redox status, thus ameliorating the early markers of DR in a model of diabetes and hypertension." | 1.36 | Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats. ( de Faria, JB; de Faria, JM; Rosales, MA; Silva, KC, 2010) |
| ") injection of 55 mg/kg STZ and a nicotinamide group (1g/kg/day) which were dosed orally for 3 days followed by (i." | 1.35 | Effect of nicotinamide on experimental induced diabetes. ( Alenzi, FQ, 2009) |
| " In conclusion, while NO bioavailability in mTALs is reduced during diabetes, free radical scavenging with tempol unmasks increased NO production that involves PP2B-dependent activation of NOS1 and NOS2." | 1.35 | PP2B-dependent NO production in the medullary thick ascending limb during diabetes. ( Carmines, PK; Foster, JM; Pollock, JS, 2009) |
| "Captopril treatment reduced MBP without affecting either NOx level or NOS-3 expression in aortas of diabetic SHR." | 1.33 | Effect of diabetes on aortic nitric oxide synthesis in spontaneously hypertensive rats; does captopril modulate this effect? ( Ibrahim, MA; Kanzaki, T; Satoh, N; Ueda, S; Yamagata, S, 2005) |
| " The protective effects may be attributable to restoration of NO bioavailability in the circulation." | 1.33 | Antioxidant N-acetylcysteine restores systemic nitric oxide availability and corrects depressions in arterial blood pressure and heart rate in diabetic rats. ( Guo, Z; McNeill, JH; Nagareddy, PR; Xia, Z; Zhang, W, 2006) |
| "The degree of contraction of the open wounds was evaluated for 2 weeks duration." | 1.33 | Collagen ultrastructure and TGF-beta1 expression preserved with aminoguanidine during wound healing in diabetic rats. ( Akalin, S; Burçak, G; Cetinel, S; Civelek, S; Deyneli, O; Haklar, G; Kaya, H; San, T; Tuğtepe, H; Uyar, S; Yavuz, D, 2005) |
| "Atorvastatin has been employed in the present study as standard agent to improve vascular endothelial dysfunction." | 1.33 | Involvement of Rho-kinase in experimental vascular endothelial dysfunction. ( Shah, DI; Singh, M, 2006) |
| "Diabetic neuropathic pain, an important microvascular complication in diabetes mellitus is recognised as one of the most difficult types of pain to treat." | 1.33 | Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain. ( Agrewala, JN; Chopra, K; Kulkarni, SK; Sharma, S, 2006) |
| "To study the protective effects of green tea (-)-epicatechin (EC) against the toxic effects of streptozotocin (STZ), a selective beta cell toxin, on pancreatic islets in vivo and in vitro." | 1.32 | Protective effects of epicatechin against the toxic effects of streptozotocin on rat pancreatic islets: in vivo and in vitro. ( Chung, JS; Hahn, SJ; Jo, YH; Kim, MJ; Kim, MS; Min, DS; Rhie, DJ; Ryu, GR; Sim, SS; Yoon, SH, 2003) |
| "Gliclazide treatment, but not glibenclamide, significantly reduced the oxidative products and NAD(P)H oxidase." | 1.32 | Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. ( Fujita, T; Goto, A; Onozato, ML; Tojo, A, 2004) |
| " Gene therapy strategies aimed at restoring cutaneous NO bioavailability may provide an effective means to ameliorate delayed diabetic wound healing." | 1.32 | Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice. ( Chen, AF; Fu, WL; Luo, JD; Wang, YY; Wu, J, 2004) |
| " Both effects (decrease in NO(2-) and increase in NO(3-)) were ameliorated by chronic administration of insulin to diabetic rats but NOx (NO(2-) plus NO(3-)) was increased." | 1.31 | Effect of chronic insulin treatment on NO production and endothelium-dependent relaxation in aortae from established STZ-induced diabetic rats. ( Kamata, K; Kobayashi, T, 2001) |
| "Ozone has been used as a therapeutical agent and beneficial effects have been observed." | 1.31 | Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats. ( Al-Dalain, SM; Candelario-Jalil, E; Giuliani, A; León, OS; Martínez, G; Menéndez, S; Re, L, 2001) |
| "Nicotine has been previously shown to have immunosuppressive actions." | 1.31 | Nicotine reduces the incidence of type I diabetes in mice. ( Mabley, JG; Pacher, P; Salzman, AL; Southan, GJ; Szabó, C, 2002) |
| "Experiments were designed to investigate the effects of chronic administration of an NO donor, (+/-)-(E)-ethyl-2-[(E)-ethylhydroxyimino]-5-nitro-3-hexeneamide (FK409), on the impairment of the acetylcholine-induced endothelium-dependent relaxations of the aorta, perfused mesenteric arterial bed and perfused kidney that seen in streptozotocin-induced diabetic rats." | 1.30 | Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat. ( Hayashi, T; Kamata, K, 1999) |
| " The present study was performed to determine the relationship between diabetic glomerular hyperfiltration and nitric oxide as modulated by the chronic administration of L-arginine and/or N-omega-nitro-L-arginine, a known nitric oxide synthase inhibitor in streptozotocin-induced diabetic rats." | 1.29 | Nitric oxide in streptozotocin-induced diabetes mellitus in rats. ( Blum, M; Cabili, S; Csernihovsky, T; Iaina, A; Maree, A; Peer, G; Silverberg, DS; Wollman, Y, 1996) |
| "The rats with diabetic acute renal failure had a much lower creatinine clearance (90 +/- 22 microliters." | 1.29 | Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats. ( Blum, M; Cabili, S; Chernihovsky, T; Goor, Y; Iaina, A; Peer, G; Silverberg, D; Wollman, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.65) | 18.7374 |
| 1990's | 16 (10.32) | 18.2507 |
| 2000's | 82 (52.90) | 29.6817 |
| 2010's | 50 (32.26) | 24.3611 |
| 2020's | 6 (3.87) | 2.80 |
| Authors | Studies |
|---|---|
| Gajos-Draus, A | 1 |
| Duda, M | 1 |
| Beresewicz, A | 1 |
| Mayyas, F | 2 |
| Al Gharram, T | 1 |
| Gheibi, S | 2 |
| Jeddi, S | 5 |
| Carlström, M | 1 |
| Kashfi, K | 2 |
| Ghasemi, A | 5 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 7 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 2 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 1 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
| Tang, LF | 1 |
| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
| Wang, LF | 1 |
| Qiu, SW | 1 |
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| Adamis, AP | 1 |
| Mabley, JG | 1 |
| Pacher, P | 1 |
| Southan, GJ | 1 |
| Salzman, AL | 1 |
| Szabó, C | 1 |
| Peralta, C | 1 |
1 review available for nitrites and Alloxan Diabetes
1 trial available for nitrites and Alloxan Diabetes
154 other studies available for nitrites and Alloxan Diabetes
| Article | Year |
|---|---|
Exercise and nitrite prevent and Nω-nitrol-L-arginine methyl ester reproduces imbalance in the nuclear factor-κB/NADPH oxidase 2 and nuclear factor erythroid 2-related factor 2/NADPH oxidase 4/endothelial nitric oxide synthase systems in diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Hydrogen Peroxide; NADPH Oxidase 2; NADPH Oxidas | 2021 |
Impact of atorvastatin on plasma and cardiac biomarkers of inflammation, oxidative stress, and fibrosis in a rat model of streptozotocin-induced diabetes.
Topics: Animals; Atorvastatin; Biomarkers; Diabetes Mellitus, Experimental; Fibrosis; Inflammation; Male; Ni | 2023 |
Hydrogen sulfide potentiates the favorable metabolic effects of inorganic nitrite in type 2 diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, | 2019 |
Effects of renal ischemia injury on brain in diabetic and non-diabetic rats: Role of angiotensin II type 2 receptor and angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Animals; Brain; Diabetes Mellitus, Experimental; Diminazene; Hyperg | 2020 |
Acidified nitrite improves wound healing in type 2 diabetic rats: Role of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hydrogen-Ion Conc | 2020 |
Efonidipine Exerts Cerebroprotective Effect by Down-regulation of TGF-β/SMAD-2-Dependent Signaling Pathway in Diabetic Rats.
Topics: Acetylcholinesterase; Animals; Brain; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dih | 2021 |
Effect of oral nitrite administration on gene expression of SNARE proteins involved in insulin secretion from pancreatic islets of male type 2 diabetic rats.
Topics: Animals; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression; Glu | 2022 |
Losartan Preserves Erectile Function by Suppression of Apoptosis and Fibrosis of Corpus Cavernosum and Corporal Veno-Occlusive Dysfunction in Diabetic Rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Collagen; Cyclic GMP; Diabetes Mellitu | 2017 |
Linalyl acetate restores endothelial dysfunction and hemodynamic alterations in diabetic rats exposed to chronic immobilization stress.
Topics: Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hear | 2018 |
Quercetin in association with moderate exercise training attenuates injuries induced by experimental diabetes in sciatic nerves.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Male; Nitric Oxide Synthase Type I | 2017 |
Effect of long-term nitrite administration on browning of white adipose tissue in type 2 diabetic rats: A stereological study.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Cyclic GMP; Diabetes | 2018 |
Role of nitric oxide in the pathogenesis of alloxan diabetes.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Male; Nitrates; | 2013 |
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabet | 2013 |
Catechin averts experimental diabetes mellitus-induced vascular endothelial structural and functional abnormalities.
Topics: Animals; Aorta; Blood Glucose; Catechin; Cytoprotection; Diabetes Mellitus, Experimental; Diabetic A | 2014 |
Antidiabetic and antioxidant effects of Annona muricata (Annonaceae), aqueous extract on streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Annona; Antioxidants; Aspartate Aminotransferases; Blood Glucose; Cat | 2014 |
Anti-inflammatory activity of dried flower extracts of Aegle marmelos in Wistar rats.
Topics: Aegle; Animals; Anti-Inflammatory Agents; Carrageenan; Diabetes Mellitus, Experimental; Edema; Ethan | 2014 |
Efficacy of bosentan, a dual ETA and ETB endothelin receptor antagonist, in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
Topics: Acetylcholinesterase; Animals; Blood Glucose; Bosentan; Brain; Dementia; Diabetes Mellitus, Experime | 2014 |
Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms.
Topics: Adenosine Kinase; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cell Line; Dextran | 2014 |
Aqueous extract of unfermented honeybush (Cyclopia maculata) attenuates STZ-induced diabetes and β-cell cytotoxicity.
Topics: Animals; Antioxidants; Blood Glucose; Cell Survival; Cyclopia Plant; Diabetes Mellitus, Experimental | 2014 |
Increased on oxidative brain injury in the diabetic rats following sepsis.
Topics: Animals; Brain; Catalase; Diabetes Mellitus, Experimental; Male; Nitrates; Nitrites; Peroxidase; Pro | 2014 |
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimenta | 2014 |
Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKA(y) mice.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cytokines; Diabetes Mellitus, Experimental; Dia | 2015 |
Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytokines; Diabetes Mellitus, Experimental; Endoplasmi | 2015 |
Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epoprostenol; | 2015 |
Calcium Channel Blockade and Peroxisome Proliferator Activated Receptor γ Agonism Diminish Cognitive Loss and Preserve Endothelial Function During Diabetes Mellitus.
Topics: Animals; Attention; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Calcium Channels; Capillar | 2016 |
Pitavastatin Exhibits Protective Effects on Podocytes Accompanied by BMP-7 Up-Regulation and Rho Suppression.
Topics: Animals; Bone Morphogenetic Protein 7; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; | 2016 |
Role of atrial natriuretic peptide in ischemic preconditioning-induced cardioprotection in the diabetic rat heart.
Topics: Alloxan; Animals; Atrial Natriuretic Factor; Blood Glucose; Diabetes Mellitus, Experimental; Drug Ev | 2016 |
Effect of ruthenium red, a ryanodine receptor antagonist in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Brain; Calcium Channel Blockers; Dementia; Diabetes Mell | 2016 |
The role of spironolactone on myocardial oxidative stress in rat model of streptozotocin-induced diabetes.
Topics: Aldosterone; Animals; Blood Pressure; Catalase; Cytochrome P-450 CYP11B2; Diabetes Mellitus, Experim | 2017 |
Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Eating; Glucose; I | 2017 |
Modulation of neuro-inflammatory condition, acetylcholinesterase and antioxidant levels by genistein attenuates diabetes associated cognitive decline in mice.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Antioxidants; Cognition Disorders; Diabetes | 2017 |
Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin I; Animals; Cyclic GMP; Diabetes Mellitus, Experime | 2017 |
Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice.
Topics: Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Interfer | 2009 |
Distinct roles of estrogen receptor-alpha and beta in the modulation of vascular inducible nitric-oxide synthase in diabetes.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Enzyme Induction; Estrogen Receptor alpha; Estrogen | 2009 |
Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Topics: Animals; Brain; Curcuma; Curcumin; Diabetes Mellitus, Experimental; Flavonoids; Lipid Peroxidation; | 2008 |
Effect of nicotinamide on experimental induced diabetes.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Insulin; | 2009 |
Propranolol improves cutaneous wound healing in streptozotocin-induced diabetic rats.
Topics: Animals; Cell Proliferation; Collagen; Diabetes Mellitus, Experimental; Granulation Tissue; Inflamma | 2009 |
Effect of Bu-Zhong-Yi-Qi-Tang on deficiency of N-glycan/nitric oxide and islet damage induced by streptozotocin in diabetic rats.
Topics: alpha-Mannosidase; Amylases; Animals; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Humans | 2009 |
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.
Topics: Amidines; Animals; Benzylamines; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclic N-Oxides | 2009 |
Interleukin-1 receptor antagonist enhances islet engraftment without impacting serum levels of nitrite or osteopontin.
Topics: Adenoviridae; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA, Complementary; | 2009 |
AMT, an inducible nitric oxide synthase inhibitor, enhances islet engraftment.
Topics: Animals; Diabetes Mellitus, Experimental; DNA, Complementary; Insulin; Interleukin 1 Receptor Antago | 2009 |
Selenium restores defective beta-adrenergic receptor response of thoracic aorta in diabetic rats.
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Cyclic AMP; Diabete | 2010 |
Omega-3E treatment regulates matrix metalloproteinases and prevents vascular reactivity alterations in diabetic rat aorta.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetic A | 2009 |
Effect of pravastatin on experimental diabetic wound healing.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibit | 2010 |
Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; | 2010 |
Insulin treatment of diabetic rats reduces cardiac function in a lipopolysaccharide-induced systemic inflammation model.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Heart Diseases; Hea | 2011 |
Effects of Kaempferia parviflora Wall. Ex Baker on endothelial dysfunction in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Diabetes Mellitus, Experimenta | 2011 |
Beneficial effect of insulin in hyperhomocysteinemia and diabetes mellitus-induced vascular endothelium dysfunction: role of phosphoinositide dependent kinase and protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Atorvastatin; Blood Glucose; Diabetes Mellitu | 2011 |
Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats.
Topics: Animals; Aorta, Thoracic; Behavior, Animal; Blood Glucose; Brain; Butyrates; Cholinesterases; Dement | 2011 |
Effect of acute alloxan diabetes on ischemic and reperfusion arrhythmias in rats with different activity of nitric oxide system.
Topics: Animals; Arrhythmias, Cardiac; Blotting, Western; Diabetes Mellitus, Experimental; Heme Oxygenase (D | 2011 |
Emblica officinalis corrects functional, biochemical and molecular deficits in experimental diabetic neuropathy by targeting the oxido-nitrosative stress mediated inflammatory cascade.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Cytokines; Diabetes M | 2011 |
Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Body Weight; Caveolin 1; Cholesterol; Collage | 2011 |
Beneficial effects of angiotensin (1-7) in diabetic rats with cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Di | 2011 |
Azelnidipine, a new calcium channel blocker, promotes skin wound healing in diabetic rats.
Topics: Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dihydr | 2011 |
Oral administration of skin gelatin isolated from Chum salmon (Oncorhynchus keta) enhances wound healing in diabetic rats.
Topics: Administration, Oral; Animals; Collagen; Diabetes Mellitus, Experimental; Gelatin; Male; Nitrites; O | 2011 |
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; | 2011 |
Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Diabe | 2012 |
Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Eye | 2012 |
Effect of dipyrone and thalidomide alone and in combination on STZ-induced diabetic neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropat | 2012 |
Mesenteric endothelial dysfunction in a cardiopulmonary bypass rat model: the effect of diabetes.
Topics: Animals; Blotting, Western; Cardiopulmonary Bypass; Diabetes Mellitus, Experimental; Dose-Response R | 2012 |
Effects of Crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Crataegus; Diabetes Mellitus, Experimental; Endothelium, Vascular; Interleukin-6; Li | 2013 |
Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.
Topics: Adamantane; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus, Experimental; Dipeptidyl-Pept | 2012 |
Thalidomide attenuates multiple low-dose streptozotocin-induced diabetes in mice by inhibition of proinflammatory cytokines.
Topics: Administration, Oral; Animals; Cytokines; Diabetes Mellitus, Experimental; Dose-Response Relationshi | 2012 |
[The changes of the activity of NO-synthases and oxidative processes under conditions of 5-HT receptors activation in the stomach and large intestine in streptozocin-induced diabetes mellitus].
Topics: Animals; Benzamides; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Gastric Mucosa; Human | 2012 |
The effects of taurine and thiotaurine on oxidative stress in the aorta and heart of diabetic rats.
Topics: Animals; Aorta; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Disease Model | 2013 |
Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis.
Topics: Acetates; Analysis of Variance; Animals; Cholesterol; Cholesterol Esters; Culture Techniques; Diabet | 2002 |
The development of insulitis and the kallikrein-kinin system.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Kal | 2002 |
[Determination of nitrite and nitrate in rat nervi ischiadicus by high performance liquid chromatography].
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Neuropathie | 2000 |
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Clopidogrel; Diabetes Mellitus, Experim | 2003 |
Protective effects of epicatechin against the toxic effects of streptozotocin on rat pancreatic islets: in vivo and in vitro.
Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Immunohistochemistry; In Situ Hyb | 2003 |
Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.
Topics: Animals; beta-Galactosidase; Diabetes Mellitus, Experimental; Erectile Dysfunction; Gene Transfer Te | 2003 |
In vitro and in vivo antioxidant effects of mustard leaf (Brassica juncea).
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Free Radical Scavengers; Inhi | 2003 |
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.
Topics: Animals; Blood-Retinal Barrier; Body Weight; Diabetes Mellitus, Experimental; Endothelial Growth Fac | 2003 |
Diabetes undermines estrogen control of inducible nitric oxide synthase function in rat aortic smooth muscle cells through overexpression of estrogen receptor-beta.
Topics: Animals; Aorta; Cells, Cultured; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; | 2003 |
Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes.
Topics: 3-Hydroxybutyric Acid; Alloxan; Animals; Blood Glucose; Blood Pressure; Body Weight; Carbon Dioxide; | 2003 |
Prevention of alloxan diabetes by sodium nitrite and paraminopropiophenone.
Topics: Animals; Diabetes Mellitus, Experimental; Nitrites; Propiophenones; Sodium Nitrite | 1954 |
[Changes in vasodilator responses of vascular smooth muscles and nitric oxide system in experimental diabetes mellitus].
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Male; Muscle, Smooth, Vascular; Myocardiu | 2003 |
Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats.
Topics: Animals; Antioxidants; Brain; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Kid | 2003 |
The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.
Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blotting, Northern; Cells, Cultured; Diabetes Mellitu | 2004 |
Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet.
Topics: Animals; Blood Pressure; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Diabetic Nephropathi | 2004 |
Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; DNA Pr | 2004 |
Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.
Topics: Acetophenones; Adenoviridae; Alkaloids; Animals; Benzophenanthridines; Biological Availability; Diab | 2004 |
Protective effects of the Chinese prescription Hachimi-jio-gan against diabetic oxidative stress.
Topics: Animals; Blood Glucose; Blood Proteins; Creatinine; Diabetes Mellitus, Experimental; Disease Models, | 2004 |
Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism.
Topics: Animals; Benzoquinones; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; I | 2005 |
Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Electrolytes; E | 2005 |
Increased matrix metalloproteinases 2 and 9 in placenta of diabetic rats at midgestation.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Gestational Age; Immunohistochemistry; Matrix Meta | 2005 |
Effects of NADPH oxidase inhibitor in diabetic nephropathy.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; | 2005 |
Effect of diabetes on aortic nitric oxide synthesis in spontaneously hypertensive rats; does captopril modulate this effect?
Topics: Animals; Aorta; Captopril; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Nitrates; N | 2005 |
15-Deoxy-Delta12,14-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism.
Topics: Acetates; Animals; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Experimental; Female; Ges | 2005 |
Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Insulin | 2005 |
Diltiazem attenuates oxidative stress in diabetic rats.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Blood Glucose; Calcium Channel Blockers; Catalase; | 2005 |
Modulatory role of green tea extract on antinociceptive effect of morphine in diabetic mice.
Topics: Analgesics; Animals; Arginine; Blood Glucose; Body Weight; Camellia sinensis; Diabetes Mellitus, Exp | 2005 |
Oxidative and nitrosative stress in brain mitochondria of diabetic rats.
Topics: Animals; Blotting, Western; Brain; Cytochromes c; Diabetes Mellitus, Experimental; Male; Mitochondri | 2005 |
Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis.
Topics: Animals; Diabetes Mellitus, Experimental; Embryo, Mammalian; Endothelin-1; Female; Immunohistochemis | 2005 |
Differences in the nitric oxide metabolism in streptozotocin-treated rats and children suffering from Type 1 diabetes.
Topics: Animals; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Humans; Leukocytes; Nitr | 2006 |
Antioxidant N-acetylcysteine restores systemic nitric oxide availability and corrects depressions in arterial blood pressure and heart rate in diabetic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Arteries; Blood Pressure; Diabetes Mellitus, Experimental; Di | 2006 |
Collagen ultrastructure and TGF-beta1 expression preserved with aminoguanidine during wound healing in diabetic rats.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Epithelium; Extrac | 2005 |
Inhibition of protein tyrosin phosphatase improves vascular endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; | 2006 |
Involvement of Rho-kinase in experimental vascular endothelial dysfunction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Antibiotics, Antineoplastic; | 2006 |
Chronic treatment with vascular endothelial growth factor preserves agonist-evoked vascular responses in the streptozotocin-induced diabetic rat.
Topics: Animals; Anions; Aorta; Diabetes Mellitus, Experimental; Nitrates; Nitric Oxide Synthase Type III; N | 2006 |
Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Brain; Cur | 2006 |
N-acetylcysteine prevents nitrosative stress-associated depression of blood pressure and heart rate in streptozotocin diabetic rats.
Topics: Acetylcysteine; Animals; Blood Glucose; Blood Pressure; Blotting, Western; Cholesterol; Diabetes Mel | 2006 |
High glucose increases B1-kinin receptor expression and signaling in endothelial cells.
Topics: Amidines; Animals; Benzylamines; Bradykinin; Diabetes Mellitus, Experimental; Endothelial Cells; Enz | 2006 |
The effects of topical treatment with acidified nitrite on wound healing in normal and diabetic mice.
Topics: Acids; Administration, Topical; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship | 2006 |
Relationship between protective effects of rosiglitazone on endothelium and endogenous nitric oxide synthase inhibitor in streptozotocin-induced diabetic rats and cultured endothelial cells.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Endotheli | 2007 |
Possible role of Akt to improve vascular endothelial dysfunction in diabetic and hyperhomocysteinemic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular | 2007 |
Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits.
Topics: Alloxan; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Female; Glucose; Homeosta | 2007 |
beta1 antagonist and beta2 agonist, celiprolol, restores the impaired endothelial dependent and independent responses and decreased TNFalpha in rat with type II diabetes.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Animals; Aorta, Abdomin | 2007 |
Enhancing engraftment of islets using perioperative sodium 4-phenylbutyrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Diabetes Mellitus, Exp | 2006 |
Diabetes and its effects on dental pulp.
Topics: Alkaline Phosphatase; Animals; Collagen; Dental Pulp; Diabetes Mellitus, Experimental; Extracellular | 2006 |
Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Blotting, Western; Cornus; Creatinine; Diabetes Mellit | 2007 |
Regulation of LPS stimulated ROS production in peritoneal macrophages from alloxan-induced diabetic rats: involvement of high glucose and PPARgamma.
Topics: Animals; Blood Glucose; Cells, Cultured; Cytosol; Diabetes Mellitus, Experimental; Lipopolysaccharid | 2007 |
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines; | 2007 |
Insulin-induced impairment via peroxynitrite production of endothelium-dependent relaxation and sarco/endoplasmic reticulum Ca(2+)-ATPase function in aortas from diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Immunohistoch | 2007 |
Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation.
Topics: Active Transport, Cell Nucleus; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B | 2007 |
Curcumin attenuates diabetic encephalopathy in rats: behavioral and biochemical evidences.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain Diseases, Metabolic; Catalase; Cerebral Corte | 2007 |
GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in
Topics: Amidohydrolases; Animals; Arginine; Catalysis; Diabetes Mellitus, Experimental; Dimethylamines; Enzy | 2007 |
Pretreatment effect of resveratrol on streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Catalase; Copper; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nit | 2007 |
The effects of vitamin E on lipid peroxidation, nitric oxide production and superoxide dismutase expression in hyperglycemic rats with cerebral ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Blood Pressure; Brain Diseases; Diabetes Mellitus, Experimental; Hyperglycemi | 2007 |
L-arginine uptake in normal and diabetic rat retina and retinal pigment epithelium.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Nitrates; Nitric Oxide; Ni | 2008 |
Possible involvement of Akt activity in endothelial dysfunction in type 2 diabetic mice.
Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clonidine; | 2008 |
Augmentation of vascular remodeling by uncoupled endothelial nitric oxide synthase in a mouse model of diabetes mellitus.
Topics: Animals; Aorta; Biopterins; Carotid Arteries; Cholesterol; Diabetes Mellitus, Experimental; Disease | 2008 |
Role of EDRF (nitric oxide) in diabetic renal hyperfiltration.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Male | 1993 |
Nitric oxide in streptozotocin-induced diabetes mellitus in rats.
Topics: Alloxan; Animals; Arginine; Creatine; Diabetes Mellitus, Experimental; Metabolic Clearance Rate; Nit | 1996 |
Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Creatinine; Diabetes Mellitus, Experim | 1996 |
Regulation of growth of cultured smooth muscle cells from diabetic rats by interleukin-1 beta: role of nitric oxide.
Topics: Animals; Cell Division; Cyclic GMP; Diabetes Mellitus, Experimental; DNA; Interleukin-1; L-Lactate D | 1996 |
Light-dependent corneal toxicity in streptozocin-treated rats.
Topics: Animals; Aqueous Humor; Cataract; Cornea; Corneal Edema; Corneal Opacity; Diabetes Mellitus, Experim | 1997 |
Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; C | 1997 |
Relative contributions of advanced glycation and nitric oxide synthase inhibition to aminoguanidine-mediated renoprotection in diabetic rats.
Topics: Administration, Oral; Albuminuria; Animals; Cohort Studies; Diabetes Mellitus, Experimental; Enzyme | 1997 |
Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA Damage; Guanidines; Insulin | 1998 |
Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation.
Topics: Animals; Clodronic Acid; Cohort Studies; Diabetes Mellitus, Experimental; Gadolinium; Graft Survival | 1998 |
Activation of peritoneal macrophages during the prediabetic phase in low-dose streptozotocin-treated mice.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Kinetics; Lact | 1997 |
Effects of diabetes mellitus on the contractile activity of carbachol and galanin in isolated gastric fundus strips of rats.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Galanin; Gastric Fundus; Hyp | 1998 |
Impairment of nitric oxide-mediated relaxations in anaesthetized autoperfused streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Anesthesia; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes M | 1998 |
Increased expression of endothelial cell nitric oxide synthase (ecNOS) in afferent and glomerular endothelial cells is involved in glomerular hyperfiltration of diabetic nephropathy.
Topics: Animals; Arterioles; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelium, Vascular; | 1998 |
Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Susceptibility; Dose-Response Relationship, Drug; | 1999 |
Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructosamin | 1999 |
Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In | 1999 |
Neuronal and endothelial nitric oxide synthase expression in outer medulla of streptozotocin-induced diabetic rat kidney.
Topics: Animals; Blotting, Southern; Diabetes Mellitus, Experimental; Gene Expression; Immunohistochemistry; | 2000 |
Role of nitric oxide in diabetes-induced attenuation of antinociceptive effect of morphine in mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Female; Guanidines; Male; Mice; Morphi | 2000 |
Preservation of the antioxidant status in chemically-induced diabetes mellitus by melatonin.
Topics: Administration, Oral; Alloxan; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes | 2000 |
Sodium fusidate ameliorates the course of diabetes induced in mice by multiple low doses of streptozotocin.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Fusidic Acid; Immunosuppressive Agents; Interfe | 2000 |
An analysis of renal nitric oxide contribution to hyperfiltration in diabetic rats.
Topics: Animals; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glomerular Filtr | 2001 |
Effect of chronic insulin treatment on NO production and endothelium-dependent relaxation in aortae from established STZ-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular | 2001 |
Diabetes-induced microvascular dysfunction in the hydronephrotic kidney: role of nitric oxide.
Topics: Animals; Blood Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathi | 2001 |
Inhibition of neuronal nitric oxide synthase ameliorates renal hyperfiltration in streptozotocin-induced diabetic rat.
Topics: Animals; Cyclic GMP; Diabetes Mellitus, Experimental; Drug Synergism; Enzyme Inhibitors; Glomerular | 2001 |
Mechanisms underlying attenuated contractile response of aortic rings to noradrenaline in fructose-fed mice.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, | 2001 |
Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats.
Topics: Animals; Biomarkers; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glycosylat | 2001 |
Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathy.
Topics: Administration, Oral; Animals; Aorta; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy | 2002 |
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo.
Topics: Animals; Cell Adhesion; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Growth Fa | 2002 |
Nicotine reduces the incidence of type I diabetes in mice.
Topics: Age of Onset; Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2002 |
Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Islets of Langerhans; Nitr | 2002 |
Modulation by hydrogen peroxide of noradrenaline-induced contraction in aorta from streptozotocin-induced diabetic rat.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; D | 2002 |
Levels of endothelin-1 in embryos from control and neonatal streptozotocin-induced diabetic rats, and their relationship with nitric oxide generation.
Topics: Abnormalities, Multiple; Animals; Animals, Newborn; Case-Control Studies; Diabetes Mellitus, Experim | 2002 |