nitrites has been researched along with Aging in 94 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report herein a novel mechanism, unraveled by proteomics and validated by in vitro and in vivo studies, of the aberrant aging-associated upregulation of ovarian transferrin and ferritin in rat ovaries." | 8.12 | Aberrant Transferrin and Ferritin Upregulation Elicits Iron Accumulation and Oxidative Inflammaging Causing Ferroptosis and Undermines Estradiol Biosynthesis in Aging Rat Ovaries by Upregulating NF-Κb-Activated Inducible Nitric Oxide Synthase: First Demon ( Lam, JKW; Lee, KF; Lin, K; Ng, ML; Ng, TB; Sze, SCW; Yung, KKL; Zhang, L; Zhang, S; Zhang, Z, 2022) |
| "Aging is associated with erectile dysfunction (ED), in which nitric oxide synthase (NOS) activity and NO bioavailability are reduced due to deficiencies of NOS cofactor (tetrahydrobiopterin, BH(4)) and substrate (L-arginine)." | 7.80 | L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats. ( Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D, 2014) |
| "The study was carried out on 37 patients (69-91 yrs) with primary hypertension, treated with perindopril for 6 weeks, and normotensive subjects who constituted the two control groups: 25 (65-96 yrs--K1) and 23 (22-41 yrs--K2)." | 7.73 | Production of nitric oxide, lipid peroxidation and oxidase activity of ceruloplasmin in blood of elderly patients with primary hypertension. Effects of perindopril treatment. ( Bartosz, G; Czuczejko, J; Kedziora, J; Kedziora-Kornatowska, K; Kornatowski, T; Pawluk, H; Szadujkis-Szadurski, L, 2006) |
| "The fact that both E and L delayed cardiac hypertrophy/hyperplasia and aortic growth and raised aortic endothelium NOS activity indicates a protective effect on cardiovascular damage due to aging, exerted through inhibition of angiotensin II." | 7.71 | Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging. ( Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA, 2001) |
| " In conclusion, (1) diminished EDHF availability accounts for the reduced Ach-relaxations produced by aging in MVB from SHR; (2) the enhancement of Ach-relaxations produced by losartan seems to be dependent on an increased NO availability; and (3) angiotensin II via angiotensin I type 1 receptor (AT1) plays an important role in the deleterious consequences of aging on endothelial function in SHR." | 7.70 | Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR. ( Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM, 1998) |
| "The present study was performed to test the hypothesis that excretion of nitric oxide metabolites, nitrate and nitrite, are decreased with progressive aging in rats and that a decrease in nitric oxide precursor, L-arginine, also decreases with aging." | 7.69 | Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging. ( Bacon, EE; Blanchard, EJ; Kellum, JA; Kruckeberg, WC; Reckelhoff, JF; Wesley, AJ, 1994) |
| "We report herein a novel mechanism, unraveled by proteomics and validated by in vitro and in vivo studies, of the aberrant aging-associated upregulation of ovarian transferrin and ferritin in rat ovaries." | 4.12 | Aberrant Transferrin and Ferritin Upregulation Elicits Iron Accumulation and Oxidative Inflammaging Causing Ferroptosis and Undermines Estradiol Biosynthesis in Aging Rat Ovaries by Upregulating NF-Κb-Activated Inducible Nitric Oxide Synthase: First Demon ( Lam, JKW; Lee, KF; Lin, K; Ng, ML; Ng, TB; Sze, SCW; Yung, KKL; Zhang, L; Zhang, S; Zhang, Z, 2022) |
| "Aging is associated with erectile dysfunction (ED), in which nitric oxide synthase (NOS) activity and NO bioavailability are reduced due to deficiencies of NOS cofactor (tetrahydrobiopterin, BH(4)) and substrate (L-arginine)." | 3.80 | L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats. ( Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D, 2014) |
| "The study was carried out on 37 patients (69-91 yrs) with primary hypertension, treated with perindopril for 6 weeks, and normotensive subjects who constituted the two control groups: 25 (65-96 yrs--K1) and 23 (22-41 yrs--K2)." | 3.73 | Production of nitric oxide, lipid peroxidation and oxidase activity of ceruloplasmin in blood of elderly patients with primary hypertension. Effects of perindopril treatment. ( Bartosz, G; Czuczejko, J; Kedziora, J; Kedziora-Kornatowska, K; Kornatowski, T; Pawluk, H; Szadujkis-Szadurski, L, 2006) |
| "The fact that both E and L delayed cardiac hypertrophy/hyperplasia and aortic growth and raised aortic endothelium NOS activity indicates a protective effect on cardiovascular damage due to aging, exerted through inhibition of angiotensin II." | 3.71 | Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging. ( Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA, 2001) |
| " In conclusion, (1) diminished EDHF availability accounts for the reduced Ach-relaxations produced by aging in MVB from SHR; (2) the enhancement of Ach-relaxations produced by losartan seems to be dependent on an increased NO availability; and (3) angiotensin II via angiotensin I type 1 receptor (AT1) plays an important role in the deleterious consequences of aging on endothelial function in SHR." | 3.70 | Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR. ( Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM, 1998) |
| "The present study was performed to test the hypothesis that excretion of nitric oxide metabolites, nitrate and nitrite, are decreased with progressive aging in rats and that a decrease in nitric oxide precursor, L-arginine, also decreases with aging." | 3.69 | Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging. ( Bacon, EE; Blanchard, EJ; Kellum, JA; Kruckeberg, WC; Reckelhoff, JF; Wesley, AJ, 1994) |
| "Effects of aging and dietary protein on the L-arginine-nitric oxide (Arg-NO) pathway and the progress of chronic nephropathy were examined." | 3.69 | L-arginine-nitric oxide pathway and chronic nephropathy in aged rats. ( Futami, Y; Maki, T; Sonaka, I, 1994) |
| "Aging is associated with loss of nephron function and reductions in serum L-arginine and excretion of nitric oxide (NO) metabolites." | 3.69 | Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function. ( Hildebrandt, DA; Kellum, JA; Racusen, LC; Reckelhoff, JF, 1997) |
| " Lower plasma nitrite and FeNO concentrations were found in older subjects, confirming the impact of ageing on NO bioavailability across different systems." | 3.11 | Pharmacokinetic Profile of Incremental Oral Doses of Dietary Nitrate in Young and Older Adults: A Crossover Randomized Clinical Trial. ( Capper, TE; Clifford, T; Iqbal, W; Siervo, M; Stevenson, EJ; Taylor, G; West, D, 2022) |
| "Aging is associated with a vasoconstrictive, pro-coagulant, and pro-inflammatory profile of arteries and a decline in the bioavailability of the endothelium-derived molecule nitric oxide." | 2.84 | Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study. ( Allen, JD; Briskey, D; Fassett, R; Hickey, D; Kerr, G; Leveritt, M; Neubauer, O; Ortiz de Zevallos Munoz, J; Parker, TJ; Peake, JM; Pecheniuk, NM; Raubenheimer, K, 2017) |
| " In eight young sedentary (23 ± 1 years; Y), eight older lifelong sedentary (66 ± 2 years; OS) and eight older lifelong physically active subjects (62 ± 2 years; OA), we studied the effect of ROS on systemic and skeletal muscle NO bioavailability and leg blood flow by infusion of the antioxidant N-acetylcysteine (NAC)." | 2.77 | Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans. ( Blackwell, JR; Damsgaard, R; Hellsten, Y; Jones, AM; Mortensen, SP; Nyberg, M, 2012) |
| " Inorganic nitrite is a promising precursor molecule for augmenting circulating and tissue NO bioavailability because it requires only a one-step reduction to NO." | 2.50 | Inorganic nitrite supplementation for healthy arterial aging. ( Devan, AE; Fleenor, BS; Seals, DR; Sindler, AL, 2014) |
| "Melatonin has been suggested as an effective free radical scavenger that might have a role during the process of aging." | 1.39 | Improvement of oxidative stress and immunity by melatonin: an age dependent study in golden hamster. ( Dash, D; Haldar, C; Mukherjee, A; Nayak, MK; Vishwas, DK, 2013) |
| "Melatonin treatment counteracted these alterations in young and aged septic rats." | 1.33 | Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment. ( Acuña-Castroviejo, D; Escames, G; López, LC; Ortiz, F; Ros, E, 2006) |
| "L-kynurenine was also formed from the reaction of nitrite with free tryptophan." | 1.31 | The Nitrite/alpha crystallin reaction: a possible mechanism in lens matrix damage. ( Dillon, J; Paik, DC, 2000) |
| " NaNO2 produced a moderate degree of developmental toxicity, but no evidence was found to suggest that the central nervous system was the target organ for the toxic effects." | 1.27 | Developmental toxicity and psychotoxicity of sodium nitrite in rats. ( Brunner, RL; Butcher, RE; Vorhees, CV; Wootten, V, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (8.51) | 18.7374 |
| 1990's | 23 (24.47) | 18.2507 |
| 2000's | 37 (39.36) | 29.6817 |
| 2010's | 21 (22.34) | 24.3611 |
| 2020's | 5 (5.32) | 2.80 |
| Authors | Studies |
|---|---|
| Capper, TE | 1 |
| Siervo, M | 3 |
| Clifford, T | 2 |
| Taylor, G | 2 |
| Iqbal, W | 2 |
| West, D | 2 |
| Stevenson, EJ | 1 |
| Capper, T | 1 |
| Stevenson, E | 1 |
| Sze, SCW | 1 |
| Zhang, L | 4 |
| Zhang, S | 3 |
| Lin, K | 1 |
| Ng, TB | 1 |
| Ng, ML | 1 |
| Lee, KF | 1 |
| Lam, JKW | 1 |
| Zhang, Z | 3 |
| Yung, KKL | 1 |
| Piknova, B | 1 |
| Park, JW | 1 |
| Thomas, SM | 1 |
| Tunau-Spencer, KJ | 1 |
| Schechter, AN | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 2 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 3 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 9 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 2 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
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| Laukhtina, E | 1 |
| Glybochko, P | 1 |
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| Xiao, BH | 1 |
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| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 2 |
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| Li, D | 2 |
| Zheng, S | 2 |
| Ma, L | 1 |
| Wang, L | 3 |
| Hu, T | 1 |
| Wang, F | 1 |
| Han, Z | 1 |
| Yin, Z | 1 |
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| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Dietary Nitrate on Vascular Function, Blood Pressure, the Oral Microbiome, and Biomarkers of Systemic Inflammation in Hypertensive Older Adults: a Randomized, Placebo-controlled Crossover Study[NCT04584372] | 20 participants (Actual) | Interventional | 2021-01-01 | Completed | |||
| Preoperative Use of Tocotrienol Associated With Personalized Nutritional and Psychoeducational Support in Women With Primary Breast Cancer.[NCT04496492] | Phase 2 | 50 participants (Actual) | Interventional | 2016-02-09 | Completed | ||
| "A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SUPPLEMENTATION WITH KIOLIC® IN PATIENTS WITH DIAGNOSIS OF METABOLIC SYNDROME TO IMPROVE ENDOTHELIAL FUNCTION AND INFLAMMATORY STATE. KYMES"[NCT01168700] | Phase 4 | 46 participants (Anticipated) | Interventional | 2009-11-30 | Recruiting | ||
| Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome[NCT02633488] | 19 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Effect of Oral Supplementation With One Form of L-arginine on Vascular Endothelial Function in Healthy Subjects Featuring Risk Factors Related to the Metabolic Syndrome.[NCT02354794] | 36 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| Characterization of the Metabolic Fate of an Oral L-arginine Form in Healthy Subjects Featuring Risk Factors Related to the Metabolic Syndrome.[NCT02352740] | 32 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
brachial artery ultrasonography % flow-mediated dilatation (FMD) for assessing endothelial function before and after an insulin clamp to assess insulin's effect on the vasculature (NCT02633488)
Timeframe: before and after 12 weeks on placebo or metformin
| Intervention | percentage of artery dilation (Mean) |
|---|---|
| Pre and Post Placebo 12 Weeks | 6.1 |
| Pre and Post Metformin 12 Weeks | 6.2 |
5 reviews available for nitrites and Aging
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Inorganic nitrite supplementation for healthy arterial aging.
Topics: Aging; Animals; Arteries; Cardiotonic Agents; Cardiovascular Diseases; Dietary Supplements; Endothel | 2014 |
Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: An individual participant meta-analysis.
Topics: Aged; Aging; Beta vulgaris; Beverages; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dietar | 2015 |
Aging, lipid modifications and phospholipases--new concepts.
Topics: Aging; Animals; Free Radicals; Humans; Lipid Metabolism; Lipid Peroxidation; Nitrates; Nitrites; Oxi | 2003 |
Aging and the role of reactive nitrogen species.
Topics: Aging; Animals; Diet; Humans; Molecular Structure; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidat | 2002 |
8 trials available for nitrites and Aging
| Article | Year |
|---|---|
Pharmacokinetic Profile of Incremental Oral Doses of Dietary Nitrate in Young and Older Adults: A Crossover Randomized Clinical Trial.
Topics: Aged; Aging; Beta vulgaris; Blood Pressure; Cross-Over Studies; Humans; Nitrates; Nitrites; Vegetabl | 2022 |
Ageing modifies acute resting blood pressure responses to incremental consumption of dietary nitrate: a randomised, cross-over clinical trial.
Topics: Adult; Aged; Aging; Beta vulgaris; Blood Pressure; Cross-Over Studies; Dietary Supplements; Humans; | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Simultaneous Pharmacokinetic Analysis of Nitrate and its Reduced Metabolite, Nitrite, Following Ingestion of Inorganic Nitrate in a Mixed Patient Population.
Topics: Administration, Oral; Aged; Aging; Biological Availability; Body Weight; Cross-Over Studies; Dietary | 2020 |
Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study.
Topics: Aged; Aging; Beta vulgaris; Biomarkers; Blood Platelets; Blood Pressure; Cardiovascular Diseases; CD | 2017 |
Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans.
Topics: Acetylcholine; Acetylcysteine; Adult; Aged; Aging; Antioxidants; Femoral Artery; Humans; Leg; Male; | 2012 |
Elevated urinary excretion of nitric oxide metabolites in young infants with Zellweger syndrome.
Topics: Aging; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Male; Nitrates; Nit | 2003 |
Estrogen therapy increases plasma concentrations of nitric oxide metabolites in postmenopausal women but increases flow-mediated vasodilation only in younger women.
Topics: Aged; Aging; Brachial Artery; Cross-Over Studies; Double-Blind Method; Estrogens, Conjugated (USP); | 2004 |
82 other studies available for nitrites and Aging
| Article | Year |
|---|---|
Aberrant Transferrin and Ferritin Upregulation Elicits Iron Accumulation and Oxidative Inflammaging Causing Ferroptosis and Undermines Estradiol Biosynthesis in Aging Rat Ovaries by Upregulating NF-Κb-Activated Inducible Nitric Oxide Synthase: First Demon
Topics: Aging; Animals; Apoferritins; Estradiol; Female; Ferritins; Ferroptosis; Iron; Iron Regulatory Prote | 2022 |
Nitrate and Nitrite Metabolism in Aging Rats: A Comparative Study.
Topics: Aging; Animals; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats | 2023 |
Oxidative stress and antioxidant responses in juvenile Brazilian flounder Paralichthys orbignyanus exposed to sublethal levels of nitrite.
Topics: Aging; Animals; Antioxidants; Dose-Response Relationship, Drug; Flounder; Nitrites; Oxidative Stress | 2018 |
Alteration in the availability of epoxyeicosatrienoic acids contributes with NO to the development of endothelial dysfunction in conduit arteries during aging.
Topics: Adult; Age Factors; Aged; Aging; Cytochrome P-450 Enzyme Inhibitors; Eicosanoids; Endothelium, Vascu | 2018 |
Influence of aging on ethanol-induced oxidative stress in digestive tract of rats.
Topics: Aging; Animals; Ethanol; Gastric Mucosa; Liver; Male; Malondialdehyde; Nitrates; Nitrites; Oxidative | 2013 |
L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats.
Topics: Aging; Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; | 2014 |
Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice.
Topics: Aging; Animals; Cytokines; Dietary Supplements; Drug Evaluation, Preclinical; Inflammation; Male; Mi | 2015 |
Pulmonary arterial hypertension in rats due to age-related arginase activation in intermittent hypoxia.
Topics: Aging; Animals; Arginase; Cell Hypoxia; Enzyme Activation; Hypertension; Lung; Male; Nitrates; Nitri | 2015 |
Effect of fetal hypothyroidism on tolerance to ischemia-reperfusion injury in aged male rats: Role of nitric oxide.
Topics: Aging; Animals; bcl-2-Associated X Protein; Congenital Hypothyroidism; Creatine Kinase; L-Lactate De | 2016 |
Metallothionein Prevents Age-Associated Cardiomyopathy via Inhibiting NF-κB Pathway Activation and Associated Nitrative Damage to 2-OGD.
Topics: Aging; Animals; Apoptosis; Cardiomyopathies; Cytokines; Energy Metabolism; Enzyme Activation; Gene E | 2016 |
Magnetic resonance imaging biomarkers of exercise-induced improvement of oxidative stress and inflammation in the brain of old high-fat-fed ApoE
Topics: Aging; Animals; Aorta; Apolipoproteins E; Biomarkers; Brain; Catalase; Cholesterol; Diet, High-Fat; | 2016 |
Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Arginine; Behavior, Animal; Catalase; Enzyme Inhibit | 2008 |
Relation of nitrite to structural and mechanical adaptation of arteries during postnatal development.
Topics: Aging; Animals; Animals, Newborn; Aorta; Arteries; Compliance; Elastic Modulus; Female; Homozygote; | 2008 |
The influence of orally administered docosahexaenoic acid on cognitive ability in aged mice.
Topics: Aging; Animals; Avoidance Learning; Basal Ganglia; Brain-Derived Neurotrophic Factor; Cognition; Die | 2009 |
Changes in the nitric oxide system contribute to effect of procyanidins extracted from the lotus seedpod ameliorating memory impairment in cognitively impaired aged rats.
Topics: Aging; Animals; Cognition; Female; Gene Expression Regulation, Enzymologic; Hippocampus; Isoenzymes; | 2011 |
Hypovolemic state: age-related influence of water restriction on cardiac nitric oxide synthase in rats.
Topics: Adaptation, Physiological; Aging; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; H | 2011 |
Oxidative stress in the kidney of reproductive male rats during aging.
Topics: Aging; Animals; Ascorbic Acid; Catalase; Estradiol; Glutathione; Glutathione Peroxidase; Glutathione | 2011 |
[Nitric oxide and human aging].
Topics: Adolescent; Aging; Blood Pressure; Female; Heart Rate; Humans; Male; Nitrates; Nitric Oxide; Nitrite | 2011 |
[Arginase-nitric oxide synthase system changes due to adaptation to swimming in adult and aged rat hearts].
Topics: Adaptation, Physiological; Aging; Animals; Arginase; Blood Pressure; Diastole; Heart; Hydrogen Perox | 2012 |
Potential hepato-protective effect of α-tocopherol or simvastatin in aged rats.
Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Antioxidants; Catalase; Lipids; Liver; Liver Diseases | 2012 |
Improvement of oxidative stress and immunity by melatonin: an age dependent study in golden hamster.
Topics: Age Factors; Aging; Animals; Bone Marrow; Catalase; Cell Cycle; Cell Proliferation; Cells, Cultured; | 2013 |
[Protective effect of Ginkgo biloba extract on acute lung injury induced by lipopolysaccharide in D-galactose aging rats].
Topics: Aging; Animals; Disease Models, Animal; Endothelin-1; Galactose; Ginkgo biloba; Lipopolysaccharides; | 2002 |
Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging.
Topics: Aging; Animals; Animals, Newborn; Astrocytoma; Heme; Hippocampus; Humans; Male; Mitochondria; Neurob | 2002 |
Age-related changes of the nitric oxide system in the rat brain.
Topics: Aging; Animals; Blotting, Western; Brain; Cerebral Decortication; Male; Nitrates; Nitric Oxide; Nitr | 2002 |
Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats.
Topics: Aging; Animals; Electron Transport Complex I; Electron Transport Complex IV; Enzyme Activation; Enzy | 2003 |
Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: antioxidant protection by gamma-tocotrienol.
Topics: Administration, Oral; Aging; Animals; Antioxidants; Blood Pressure; Blood Vessels; Chromans; Dose-Re | 2003 |
17beta-Oestradiol enhances aortic endothelium function and smooth muscle contraction in male spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Culture Techniques; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; | 2004 |
The effect of age and calorie restriction on HIF-1-responsive genes in aged liver.
Topics: Aging; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Caloric Restriction; DNA-Binding Pro | 2005 |
Assessment of the nitric oxide system in the heart, aorta and kidney of aged Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Ve | 2005 |
Production of nitric oxide, lipid peroxidation and oxidase activity of ceruloplasmin in blood of elderly patients with primary hypertension. Effects of perindopril treatment.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Ceruloplasmin; Humans; Hypertension; | 2006 |
Enhanced locomotor activity in adult rats with neonatal administration of N-omega-nitro-L-arginine.
Topics: Aging; Animals; Animals, Newborn; Environment; Enzyme Inhibitors; Female; Male; Motor Activity; Nitr | 2006 |
Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic-ischemic brain injury in neonatal rats.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Asphyxia Neonatorum; Brain; Brain Infarction; Cerebral | 2006 |
Age-dependent lipopolysaccharide-induced iNOS expression and multiorgan failure in rats: effects of melatonin treatment.
Topics: Aging; Animals; Antioxidants; Endotoxemia; Enzyme Induction; Injections; Kidney Diseases; Lipid Pero | 2006 |
Pro-inflammatory effects of early non-enzymatic glycated proteins in human mesothelial cells vary with cell donor's age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cells, Cultured; Cyclooxygenase 2; Cytokines; Epithelium; Gen | 2006 |
Serum nitric oxide metabolite (NO(x)) levels in hypertensive patients at rest: a comparison of age, gender, blood pressure and complications using normotensive controls.
Topics: Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Blood Pressure; Ca | 2007 |
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Amidines; Animals; Apoptosis; Benzylam | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Topics: Adult; Age Factors; Aging; Biomarkers; Body Mass Index; Brachial Artery; Cholesterol, LDL; Endotheli | 2008 |
Developmental toxicity and psychotoxicity of sodium nitrite in rats.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Female; Growth; Male; Nitrites; Rats; Rats, Inbred St | 1984 |
Age-dependent changes of NO synthase activity in the rat brain.
Topics: Aging; Animals; Brain; Brain Stem; Calcium; Cerebellum; Citrulline; Frontal Lobe; Hippocampus; In Vi | 1995 |
Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging.
Topics: Aging; Animals; Arginine; Fasting; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrite | 1994 |
L-arginine-nitric oxide pathway and chronic nephropathy in aged rats.
Topics: Aging; Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Chronic Disease; Creatinine; Dietary Pro | 1994 |
Decrease in free-radical production with age in rat peritoneal macrophages.
Topics: Aging; Animals; Biological Transport; Cells, Cultured; Female; Free Radicals; Glucose; Hydrogen Pero | 1995 |
Nitric oxide and endothelin 1 during postnatal life.
Topics: Aging; Endothelin-1; Fetal Blood; Humans; Infant, Newborn; Nitrates; Nitric Oxide; Nitrites; Referen | 1996 |
Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats.
Topics: Absorptiometry, Photon; Aging; Animals; Blood Pressure; Body Weight; Bone and Bones; Bone Density; E | 1996 |
Urinary nitrite/nitrate excretion in infancy: comparison between term and preterm infants.
Topics: Aging; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Nitrates; Nitric Oxide; Nitrites | 1997 |
Age-related changes of urinary nitrite/nitrate excretion in normal children.
Topics: Adolescent; Aging; Child; Child, Preschool; Female; Humans; Infant; Male; Nitrates; Nitric Oxide; Ni | 1997 |
Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.
Topics: Aging; Animals; Arginine; Body Weight; Cell Movement; Diet; Hemodynamics; Kidney; Kidney Glomerulus; | 1997 |
Age-dependent augmentation of cardiac endothelial NOS in a genetic rat model of heart failure.
Topics: Aging; Animals; Endothelium, Vascular; Heart; Heart Failure; Heart Ventricles; Male; Nitrates; Nitri | 1997 |
No changes in cerebrospinal fluid levels of nitrite, nitrate and cyclic GMP with aging. Short communication.
Topics: Adult; Aged; Aging; Cyclic GMP; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 1997 |
Alterations of nitric oxide synthase expression with aging and hypertension in rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Endothelium, Vascular; Enzyme Induc | 1998 |
Klotho protein protects against endothelial dysfunction.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Cardiovascular System; Disease Models, Animal; Endo | 1998 |
Effects of interleukin-12 in vitro on pancreatic islets isolated from normal rodents and from non-obese diabetic mice.
Topics: Aging; Animals; Culture Techniques; Depression, Chemical; DNA; Female; Glucose; Insulin; Insulin Sec | 1998 |
Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Respons | 1998 |
Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Topics: Aging; Animals; Cyclic GMP; Gene Expression Regulation, Developmental; Gene Expression Regulation, E | 1998 |
Hypotension induced by exercise is associated with enhanced release of adenyl purines from aged rat artery.
Topics: Adenine Nucleotides; Adenosine; Aging; Animals; Arteries; Blood Pressure; Cholesterol; Fatty Acids; | 1999 |
Cerebrospinal fluid nitric oxide metabolites in painful diseases.
Topics: Adult; Aged; Aged, 80 and over; Aging; Appendicitis; Female; Fractures, Bone; Humans; Lumbosacral Re | 1999 |
Analysis of urinary nitric oxide metabolites in healthy subjects.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Chromatography, High Press | 1999 |
Influence of circadian time, ageing, and hypertension on the urinary excretion of nitric oxide metabolites in rats.
Topics: Aging; Animals; Creatinine; Diuresis; Drinking; Enzyme Inhibitors; Hypertension; Male; NG-Nitroargin | 1999 |
Link between catecholamine and nitric oxide metabolism.
Topics: Aging; Animals; Catecholamines; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Rats; Selegilin | 1999 |
The Nitrite/alpha crystallin reaction: a possible mechanism in lens matrix damage.
Topics: Aging; Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis | 2000 |
Influence of age on nitric oxide modulatory action on Na(+), K(+)-ATPase activity through cyclic GMP pathway in proximal rat trachea.
Topics: Aging; Animals; Ca(2+) Mg(2+)-ATPase; Cyclic GMP; Enzyme Inhibitors; Indicators and Reagents; Male; | 2000 |
Deficits in nitric oxide production after tetanic stimulation are related to the reduction of long-term potentiation in Schaffer-CA1 synapses in aged Fischer 344 rats.
Topics: Action Potentials; Aging; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Long-Term P | 2000 |
Increase of reactive oxygen (ROS) and nitrogen (RNS) species generated by phagocyting granulocytes related to age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Granulocytes; Humans; Male; Middle Aged; Nitrites; Ph | 2000 |
Age-associated changes in nitric oxide metabolites nitrite and nitrate.
Topics: Adolescent; Adult; Aging; Arteriosclerosis; Child; Cholesterol; Creatinine; Endothelium, Vascular; H | 2000 |
Inverse regulation of endothelin-1 and nitric oxide metabolites in tissue with aging: implications for the age-dependent increase of cardiorenal disease.
Topics: Aging; Animals; Endothelin-1; Female; Heart Diseases; Kidney Diseases; Male; Mice; Mice, Inbred C57B | 2000 |
Age-related alterations of nitric oxide production in the brains of seizure-susceptible EL mice.
Topics: Aging; Animals; Body Weight; Brain; Cell Count; Cerebral Cortex; Corpus Striatum; Hippocampus; Mice; | 2000 |
Effects of aging and alterations in dietary sodium intake on total nitric oxide production.
Topics: Adult; Age Factors; Aged; Aging; Blood Pressure; Cyclic GMP; Female; Humans; Hypertension; Male; Mid | 2001 |
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Cells, | 2001 |
Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; A | 2001 |
High constitutional nitrate status in young cattle.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Animals, Suckling; Cat | 2001 |
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Kidney; Male; Nitri | 2001 |
Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis.
Topics: Aging; Angioplasty, Balloon, Coronary; Animals; Aspirin; Coronary Restenosis; Coronary Vessels; Dise | 2002 |
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aging; Animals; Arginine; Arterioles; Blotti | 2002 |
Alpha- and beta-adrenergic mechanisms in the aorta of newborn rabbits and guinea-pigs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Aorta; Female | 1979 |
The relationship between age and relaxation of vascular smooth muscle in the rabbit and rat.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Musc | 1976 |
Measurements of serum levels of nitrate ions in men and women: implications of endothelium-derived relaxing factor in blood pressure regulation and atherosclerosis.
Topics: Adult; Aging; Arteriosclerosis; Blood Glucose; Blood Pressure; Cholesterol; Female; Humans; Male; Ni | 1992 |
Influence of dietary nitrate on nitrite level of human saliva.
Topics: Adolescent; Adult; Aging; Child; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Paroti | 1992 |
[Effect of nitrates transferred from the mother on fetal hemoglobin and methemoglobin dynamics of lambs].
Topics: Aging; Animals; Animals, Newborn; Female; Fetal Hemoglobin; Lactation; Maternal-Fetal Exchange; Meth | 1987 |
[Structural and functional changes in reactivating cells of Nitrobacter winogradskyi Buch].
Topics: Adenosine Triphosphatases; Aging; Carbon; Carbon Dioxide; Cell Membrane; Cytochromes; Cytoplasmic Gr | 1971 |
Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.
Topics: Aging; Animals; Aorta, Thoracic; Benzyl Compounds; Bucladesine; Cyclic AMP; Cyclic GMP; Dose-Respons | 1974 |
Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Female; In Vitro Techniques; Isoproterenol; Male; Nitrites; Phentol | 1971 |
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical | 1968 |