Page last updated: 2024-11-01

nitrendipine and Reperfusion Injury

nitrendipine has been researched along with Reperfusion Injury in 3 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"We investigated the relationships among N-methyl-D-aspartate, glycine, L-type voltage-dependent calcium channels, and [3H]dopamine release in a canine model of global cerebral ischemia/reperfusion."7.69Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion. ( Blanck, TJ; Fiskum, G; Fox, LG; Hoehner, PJ; Hurt, KJ; Rosenthal, RE; Werling, LL, 1994)
"We investigated the relationships among N-methyl-D-aspartate, glycine, L-type voltage-dependent calcium channels, and [3H]dopamine release in a canine model of global cerebral ischemia/reperfusion."3.69Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion. ( Blanck, TJ; Fiskum, G; Fox, LG; Hoehner, PJ; Hurt, KJ; Rosenthal, RE; Werling, LL, 1994)
"Pretreatment with verapamil (10 micrograms/kg/min delivered intravenously) prevented the fall in GFR (320 +/- 70 microliters/min 100 g), as did pretreatment with nitrendipine, 1 micrograms/kg/min (460 +/- 90 microliters/min/100 g)."1.28Evidence that calcium channel blockade prevents cyclosporine-induced exacerbation of renal ischemic injury. ( Bia, MJ; Tyler, K, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lepore, DA1
Knight, KR1
Bhattacharya, S1
Ritz, M1
Robbins, SP1
Sieg, P1
Morrison, WA1
O'Brien, BM1
Werling, LL1
Hoehner, PJ1
Hurt, KJ1
Fox, LG1
Blanck, TJ1
Rosenthal, RE1
Fiskum, G1
Bia, MJ1
Tyler, K1

Other Studies

3 other studies available for nitrendipine and Reperfusion Injury

ArticleYear
Drug mixture which improves survival of ischemic rabbit epigastric skin flaps.
    Microsurgery, 1994, Volume: 15, Issue:10

    Topics: Adenosine Triphosphate; Animals; Deferoxamine; Dextrans; Drug Combinations; Epoprostenol; Heparin; I

1994
Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion.
    Journal of neurochemistry, 1994, Volume: 63, Issue:1

    Topics: Animals; Brain Ischemia; Calcium Channels; Dogs; Dopamine; Female; Glycine; Isradipine; N-Methylaspa

1994
Evidence that calcium channel blockade prevents cyclosporine-induced exacerbation of renal ischemic injury.
    Transplantation, 1991, Volume: 51, Issue:2

    Topics: Animals; Blood Pressure; Calcium Channels; Cyclosporins; Diuresis; Glomerular Filtration Rate; Kidne

1991