nitrendipine has been researched along with Pulmonary Hypertension in 9 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes." | 7.69 | [Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994) |
| "Pulmonary artery pressure (PAP), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), blood pressure (BP) were monitored before and after hypoxia, Captopril and Nitrendipine injected (7 mg/kg and 100 micrograms/kg) in group A(n = 9), and group B(n = 7) respectively results showed that during hypoxia PAP in all the pigs increased significantly (P < 0." | 7.68 | [Comparative studies between the effects of captopril and nitrendipine on the hemodynamics and angiotensin converting enzyme of pigs with acute hypoxic pulmonary hypertension]. ( Zhong, SQ, 1992) |
| "In 10 patients with precapillary pulmonary hypertension due to pulmonary fibrosis, the arterial blood pressure, right heart hemodynamics, cardiac output, and arterial oxygen partial pressure were measured to evaluate the benefits of acute sublingual (5 mg) nitrendipine." | 7.67 | Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis. ( Buhl, R; Burger, W; Jandl, M; Kober, G; Schultze-Werninghaus, G; Sievert, H, 1988) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 7.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| "To explore the effect of dimethyl 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DCDDP) on pulmonary hypertension (PH) induced by monocrotaline (MCT), the parameters of pulmonary hemodynamics, the contents of endothelin-like immunoreactivity, nitric oxide (NO), malondialdehyde, and superoxide dismutase in plasma and pulmonary homogenate were measured." | 3.71 | Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat. ( Li, ZC; Mei, QB; Song, JC; Zhang, FQ; Zhao, DH, 2002) |
| "Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes." | 3.69 | [Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994) |
| "Pulmonary artery pressure (PAP), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), blood pressure (BP) were monitored before and after hypoxia, Captopril and Nitrendipine injected (7 mg/kg and 100 micrograms/kg) in group A(n = 9), and group B(n = 7) respectively results showed that during hypoxia PAP in all the pigs increased significantly (P < 0." | 3.68 | [Comparative studies between the effects of captopril and nitrendipine on the hemodynamics and angiotensin converting enzyme of pigs with acute hypoxic pulmonary hypertension]. ( Zhong, SQ, 1992) |
| "In 10 patients with precapillary pulmonary hypertension due to pulmonary fibrosis, the arterial blood pressure, right heart hemodynamics, cardiac output, and arterial oxygen partial pressure were measured to evaluate the benefits of acute sublingual (5 mg) nitrendipine." | 3.67 | Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis. ( Buhl, R; Burger, W; Jandl, M; Kober, G; Schultze-Werninghaus, G; Sievert, H, 1988) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 3.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodat-Despoix, L | 1 |
| Aires, V | 1 |
| Ducret, T | 1 |
| Marthan, R | 1 |
| Savineau, JP | 1 |
| Rousseau, E | 1 |
| Guibert, C | 1 |
| Li, MR | 1 |
| Chen, SC | 1 |
| Ma, G | 1 |
| Wang, Y | 1 |
| Enzan, K | 1 |
| Schultz, E | 1 |
| Mitchell, MD | 1 |
| Stavros, F | 1 |
| Staub, NC | 1 |
| Xu, J | 1 |
| Hou, S | 1 |
| Chen, S | 1 |
| Li, ZC | 1 |
| Zhang, FQ | 1 |
| Song, JC | 1 |
| Mei, QB | 1 |
| Zhao, DH | 1 |
| Zhong, SQ | 1 |
| Burger, W | 2 |
| Jandl, M | 2 |
| Gellert, J | 1 |
| Schultze-Werninghaus, G | 2 |
| Kober, G | 2 |
| Buhl, R | 1 |
| Sievert, H | 1 |
| Michael, JR | 1 |
| Kennedy, TP | 1 |
| Buescher, P | 1 |
| Farrukh, I | 1 |
| Lodato, R | 1 |
| Rock, PC | 1 |
| Gottlieb, J | 1 |
| Gurtner, G | 1 |
| de la Monte, SM | 1 |
| Hutchins, GM | 1 |
1 trial available for nitrendipine and Pulmonary Hypertension
| Article | Year |
|---|---|
Acute and chronic effects of nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis.
Topics: Adult; Atrial Function, Right; Blood Pressure; Female; Heart Rate; Humans; Hypertension, Pulmonary; | 1991 |
8 other studies available for nitrendipine and Pulmonary Hypertension
| Article | Year |
|---|---|
Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.
Topics: Aged; Calcium; Escin; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Muscle Contraction | 2009 |
[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats].
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nifedipin | 1994 |
Pulmonary hypertensive response to rabbit blood components in goats: role of thromboxane.
Topics: Animals; Blood Physiological Phenomena; Chlorpheniramine; Female; Goats; Hemodynamics; Hypertension, | 1993 |
[The role of endothelin the development of hypoxic pulmonary hypertension].
Topics: Animals; Calcium Channel Blockers; Endothelins; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male | 1995 |
Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chronic Disease; Dicarbo | 2002 |
[Comparative studies between the effects of captopril and nitrendipine on the hemodynamics and angiotensin converting enzyme of pigs with acute hypoxic pulmonary hypertension].
Topics: Animals; Captopril; Female; Hypertension, Pulmonary; Hypoxia; Male; Nitrendipine; Peptidyl-Dipeptida | 1992 |
Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis.
Topics: Administration, Sublingual; Adult; Blood Pressure; Coronary Circulation; Exercise; Female; Humans; H | 1988 |
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle | 1986 |