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nitrendipine and Pulmonary Fibrosis

nitrendipine has been researched along with Pulmonary Fibrosis in 2 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"In 10 patients with precapillary pulmonary hypertension due to pulmonary fibrosis, the arterial blood pressure, right heart hemodynamics, cardiac output, and arterial oxygen partial pressure were measured to evaluate the benefits of acute sublingual (5 mg) nitrendipine."7.67Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis. ( Buhl, R; Burger, W; Jandl, M; Kober, G; Schultze-Werninghaus, G; Sievert, H, 1988)
"In 10 patients with precapillary pulmonary hypertension due to pulmonary fibrosis, the arterial blood pressure, right heart hemodynamics, cardiac output, and arterial oxygen partial pressure were measured to evaluate the benefits of acute sublingual (5 mg) nitrendipine."3.67Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis. ( Buhl, R; Burger, W; Jandl, M; Kober, G; Schultze-Werninghaus, G; Sievert, H, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burger, W2
Jandl, M2
Gellert, J1
Schultze-Werninghaus, G2
Kober, G2
Buhl, R1
Sievert, H1

Trials

1 trial available for nitrendipine and Pulmonary Fibrosis

ArticleYear
Acute and chronic effects of nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis.
    Clinical cardiology, 1991, Volume: 14, Issue:3

    Topics: Adult; Atrial Function, Right; Blood Pressure; Female; Heart Rate; Humans; Hypertension, Pulmonary;

1991

Other Studies

1 other study available for nitrendipine and Pulmonary Fibrosis

ArticleYear
Effects of 5 mg sublingual nitrendipine in patients with precapillary pulmonary hypertension due to pulmonary fibrosis.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 4

    Topics: Administration, Sublingual; Adult; Blood Pressure; Coronary Circulation; Exercise; Female; Humans; H

1988