nitrendipine has been researched along with Proteinuria in 11 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a 6-week treatment with the calcium channel blocker nitrendipine or the angiotensin converting enzyme inhibitor enalapril on blood pressure, albuminuria, renal hemodynamics, and morphology of the nonclipped kidney was studied in rats with two-kidney, one clip renovascular hypertension." | 7.68 | Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension. ( Helmchen, U; Schoeppe, W; Schwietzer, G; Troschau, G; Wenzel, UO, 1992) |
| "In older patients with isolated systolic hypertension, antihypertensive treatment starting with the dihydropyridine calcium-channel blocker, nitrendipine, did not decrease blood pressure at the expense of renal function and prevented the development of proteinuria, especially in diabetic patients." | 5.09 | Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. ( Birkenhäger, WH; de Leeuw, PW; Efstratopoulos, AD; Fagard, R; Leonetti, G; Nachev, C; Rodicio, JL; Staessen, JA; Thijs, L; Tuomilehto, J; Voyaki, SM; Wang, JG, 2001) |
| "The effect of a 6-week treatment with the calcium channel blocker nitrendipine or the angiotensin converting enzyme inhibitor enalapril on blood pressure, albuminuria, renal hemodynamics, and morphology of the nonclipped kidney was studied in rats with two-kidney, one clip renovascular hypertension." | 3.68 | Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension. ( Helmchen, U; Schoeppe, W; Schwietzer, G; Troschau, G; Wenzel, UO, 1992) |
| "Chronic administration of nitrendipine (N) prevented the development of serious renal damage in Wistar rats with experimental glomerulonephritis." | 3.67 | Comparison of BAY e 5009 (nitrendipine) with dihydralazine in Wistar rats with experimentally induced nephritis. ( Mohácsi, G; Sonkodi, S, 1988) |
| "Pretreatment with nitrendipine did not reduce enzyme excretion, although AAP levels were lower in general in the group assigned to the 20-mg dose." | 2.68 | Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration. ( Artero, M; Carraro, M; Cova, M; Faccini, L; Grotto, M; Mancini, W; Stacul, F, 1996) |
| "Enalapril treatment (5 mg/kg/day, n = 11) or felodipine (30 mg/kg/day, n = 11) reduced systolic blood pressure to a comparable degree." | 1.27 | Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat. ( Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 2 |
| Li, QX | 2 |
| Xie, XF | 1 |
| Ao, Y | 1 |
| Tie, CR | 1 |
| Song, RJ | 1 |
| Ishimitsu, T | 1 |
| Honda, T | 1 |
| Ohta, S | 1 |
| Akashiba, A | 1 |
| Takahashi, T | 1 |
| Kameda, T | 1 |
| Yoshii, M | 1 |
| Minami, J | 1 |
| Takahashi, M | 1 |
| Ono, H | 1 |
| Matsuoka, H | 1 |
| Liu, LL | 1 |
| Xia, L | 1 |
| Shao, L | 1 |
| Remuzzi, A | 1 |
| Imberti, O | 1 |
| Puntorieri, S | 1 |
| Malanchini, B | 1 |
| Macconi, D | 1 |
| Magrini, L | 1 |
| Bertani, T | 1 |
| Remuzzi, G | 1 |
| Carraro, M | 1 |
| Mancini, W | 1 |
| Artero, M | 1 |
| Stacul, F | 1 |
| Grotto, M | 1 |
| Cova, M | 1 |
| Faccini, L | 1 |
| Schwenger, V | 1 |
| Zeier, M | 1 |
| Ritz, E | 1 |
| Voyaki, SM | 1 |
| Staessen, JA | 1 |
| Thijs, L | 1 |
| Wang, JG | 1 |
| Efstratopoulos, AD | 1 |
| Birkenhäger, WH | 1 |
| de Leeuw, PW | 1 |
| Leonetti, G | 1 |
| Nachev, C | 1 |
| Rodicio, JL | 1 |
| Tuomilehto, J | 1 |
| Fagard, R | 1 |
| Kopf, D | 1 |
| Schmitz, H | 1 |
| Beyer, J | 1 |
| Frank, M | 1 |
| Bockisch, A | 1 |
| Lehnert, H | 1 |
| Wenzel, UO | 1 |
| Troschau, G | 1 |
| Schoeppe, W | 1 |
| Helmchen, U | 1 |
| Schwietzer, G | 1 |
| Jackson, B | 1 |
| Cubela, R | 1 |
| Debrevi, L | 1 |
| Whitty, M | 1 |
| Johnston, CI | 1 |
| Mohácsi, G | 1 |
| Sonkodi, S | 1 |
3 trials available for nitrendipine and Proteinuria
| Article | Year |
|---|---|
Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Albuminuria; Alpha-Globulins; Angiography, Digital | 1996 |
Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.
Topics: Aged; Antihypertensive Agents; Creatinine; Diabetes Complications; Double-Blind Method; Enalapril; E | 2001 |
A double-blind trial of perindopril and nitrendipine in incipient diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 2001 |
8 other studies available for nitrendipine and Proteinuria
| Article | Year |
|---|---|
Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.
Topics: Acetylglucosaminidase; Amlodipine; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrog | 2009 |
Cardiorenal protective effects of year-long antihypertensive therapy with an angiotensin-converting enzyme inhibitor or a calcium channel blocker in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; C | 2006 |
Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.
Topics: Amlodipine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calci | 2007 |
Dissociation between antiproteinuric and antihypertensive effect of angiotensin converting enzyme inhibitors in rats.
Topics: Alpha-Globulins; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Electrop | 1994 |
Antihypertensive therapy in renal patients - benefits and difficulties.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive A | 1999 |
Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension.
Topics: Albuminuria; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Enalapril; Hemodyn | 1992 |
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Expe | 1987 |
Comparison of BAY e 5009 (nitrendipine) with dihydralazine in Wistar rats with experimentally induced nephritis.
Topics: Animals; Antibodies; Basement Membrane; Blood Pressure; Dihydralazine; Glomerulonephritis; Hydralazi | 1988 |