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nitrendipine and Obesity

nitrendipine has been researched along with Obesity in 9 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Combination therapy of nitrendipine and atenolol may significantly increase BW and fasting BG in overweight or obese patients with hypertension."9.14Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients. ( Qin, YW; Qiu, JL; Zhang, JL; Zhao, XX; Zheng, X; Zou, DJ, 2009)
"Combination therapy of nitrendipine and atenolol may significantly increase BW and fasting BG in overweight or obese patients with hypertension."5.14Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients. ( Qin, YW; Qiu, JL; Zhang, JL; Zhao, XX; Zheng, X; Zou, DJ, 2009)
"Nitrendipine treatment 1) lowered fasting serum insulin from 265 +/- 24 to 194 +/- 22 pmol/L (P < 0."2.67Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men. ( Arocha, IR; Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (77.78)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, JL1
Zheng, X1
Zou, DJ1
Qiu, JL1
Zhao, XX1
Qin, YW1
Zawalich, WS1
Tesz, GJ1
Zawalich, KC1
Beer, NA1
Jakubowicz, DJ1
Beer, RM1
Arocha, IR1
Nestler, JE1
Draznin, B2
Jones, BH1
Kim, JH1
Zemel, MB1
Woychik, RP1
Michaud, EJ1
Wilkison, WO1
Moustaid, N1
Zhou, YP1
Cockburn, BN1
Pugh, W1
Polonsky, KS1
Byyny, RL1
LoVerde, M1
Lloyd, S1
Mitchell, W1
Valensi, P2
Uzzan, B2
Attali, JR2
Perret, G2
Vassy, R1

Reviews

1 review available for nitrendipine and Obesity

ArticleYear
Cytosolic calcium and insulin resistance.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:6 Suppl 3

    Topics: Animals; Calcium; Humans; Hypertension; Insulin Resistance; Nitrendipine; Obesity

1993

Trials

4 trials available for nitrendipine and Obesity

ArticleYear
Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients.
    American journal of hypertension, 2009, Volume: 22, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Body Mass Index

2009
Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1

    Topics: Adult; Analysis of Variance; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandros

1993
Effects of nifedipine and nitrendipine on insulin secretion in obese patients.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 1

    Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Double-Blind Method; Female; Humans; Hyperten

1991
Effect of nifedipine and nitrendipine on insulin release in non-diabetic obese patients: a double-blind, placebo-controlled study.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:8

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Glucose; Humans; Insulin; Insulin Secretion; M

1991

Other Studies

4 other studies available for nitrendipine and Obesity

ArticleYear
Inhibitors of phosphatidylinositol 3-kinase amplify insulin release from islets of lean but not obese mice.
    The Journal of endocrinology, 2002, Volume: 174, Issue:2

    Topics: Analysis of Variance; Androstadienes; Animals; Blotting, Western; Calcium Channel Blockers; Cells, C

2002
Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 1

    Topics: Adipocytes; Agouti Signaling Protein; Animals; Cell Line; Fatty Acid Synthases; Female; Gene Express

1996
Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:7

    Topics: Animals; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Diazoxide; Enzyme Inhibitors; G

1999
Cytosolic calcium and insulin resistance in elderly patients with essential hypertension.
    American journal of hypertension, 1992, Volume: 5, Issue:7

    Topics: Adipose Tissue; Aged; Aging; Blood Glucose; Calcium; Cytosol; Deoxyglucose; Glucose Tolerance Test;

1992