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nitrendipine and Myocardial Ischemia

nitrendipine has been researched along with Myocardial Ischemia in 4 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"However, in the case of anoxia-induced MYO release, nitrendipine markedly and significantly reduced this in hearts from ethanol-treated rats but had only a very small effect on the same parameter in controls."5.30Increased sensitivity to damaging effects of hypoxia and anoxia of isolated hearts from rats after prolonged exposure to ethanol: apparent protection by nitrendipine. ( Guppy, LJ; Littleton, JM, 1999)
" Two of the patients could not be treated with 5-FU any more because they had developed a myocardial ischemia, which was most likely caused by fluorouracil."3.785-FU-induced cardiac toxicity--an underestimated problem in radiooncology? ( Hautmann, MG; Kölbl, O; Steger, F, 2012)
"NT reduced the duration of continuous arrhythmias at the beginning of reperfusion (to 59."1.31Comparison of effects of nitrendipine, lacidipine and mibefradil on postischaemic myocardial damage in isolated rat hearts. ( Arh, M; Budihna, MV, 2000)
"However, in the case of anoxia-induced MYO release, nitrendipine markedly and significantly reduced this in hearts from ethanol-treated rats but had only a very small effect on the same parameter in controls."1.30Increased sensitivity to damaging effects of hypoxia and anoxia of isolated hearts from rats after prolonged exposure to ethanol: apparent protection by nitrendipine. ( Guppy, LJ; Littleton, JM, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Steger, F1
Hautmann, MG1
Kölbl, O1
Bersohn, MM1
Morey, AK1
Weiss, RS1
Guppy, LJ1
Littleton, JM1
Arh, M1
Budihna, MV1

Other Studies

4 other studies available for nitrendipine and Myocardial Ischemia

ArticleYear
5-FU-induced cardiac toxicity--an underestimated problem in radiooncology?
    Radiation oncology (London, England), 2012, Dec-15, Volume: 7

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma; Cardiotoxins; Chemoradiotherapy; Electrocardiograp

2012
Sarcolemmal calcium transporters in myocardial ischemia.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:9

    Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium Ch

1997
Increased sensitivity to damaging effects of hypoxia and anoxia of isolated hearts from rats after prolonged exposure to ethanol: apparent protection by nitrendipine.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:5

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Hypoxia; Disease Models, Animal; E

1999
Comparison of effects of nitrendipine, lacidipine and mibefradil on postischaemic myocardial damage in isolated rat hearts.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:5 Suppl

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Fem

2000