nitrendipine has been researched along with Myocardial Infarction in 14 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of felodipine, a new calcium antagonist, in monotherapy for mild and moderate hypertension was investigated in a placebo-controlled double-blind study of 109 patients from 13 centres." | 9.06 | Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension. ( Barnes, PC; Bowles, RM; Comerford, MB; Ginks, SE; Ginks, WR; Goves, JR; Grabau, WJ; Hamilton, DV; Malcolm, JP; Rajaratnam, DV, 1987) |
| "Nisoldipine was more effective in preventing cardiac necrosis as compared to nitrendipine and nimodipine." | 5.29 | Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats. ( Kaur, AH; Mathur, SK; Singh, J; Srivastava, RK, 1995) |
| "The role of felodipine, a new calcium antagonist, in monotherapy for mild and moderate hypertension was investigated in a placebo-controlled double-blind study of 109 patients from 13 centres." | 5.06 | Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension. ( Barnes, PC; Bowles, RM; Comerford, MB; Ginks, SE; Ginks, WR; Goves, JR; Grabau, WJ; Hamilton, DV; Malcolm, JP; Rajaratnam, DV, 1987) |
| " Two of the patients could not be treated with 5-FU any more because they had developed a myocardial ischemia, which was most likely caused by fluorouracil." | 3.78 | 5-FU-induced cardiac toxicity--an underestimated problem in radiooncology? ( Hautmann, MG; Kölbl, O; Steger, F, 2012) |
| "T-type Ca(2+) channel blockade reduced arrhythmias in a mouse model of dilated cardiomyopathy by repolarizing the resting membrane potential and improving cardiac autonomic nervous system imbalance." | 1.35 | T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. ( Arai, Y; Fujiwara, M; Harada, M; Kinoshita, H; Kuwabara, Y; Kuwahara, K; Murakami, M; Nakagawa, Y; Nakanishi, M; Nakao, K; Takano, M; Ueshima, K; Yasuno, S, 2009) |
| "Nisoldipine was more effective in preventing cardiac necrosis as compared to nitrendipine and nimodipine." | 1.29 | Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats. ( Kaur, AH; Mathur, SK; Singh, J; Srivastava, RK, 1995) |
| "Pretreatment with oxodipine significantly reduced the infarct size in the apical and basal myocardium (P < 0." | 1.29 | Effects of oxodipine and nitrendipine on the size of experimental myocardial infarct in the rat. ( Gil-Loyzaga, P; Merchàn-Pérez, A; Pérez-Cao, A; Tamargo, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinoshita, H | 1 |
| Kuwahara, K | 1 |
| Takano, M | 1 |
| Arai, Y | 1 |
| Kuwabara, Y | 1 |
| Yasuno, S | 1 |
| Nakagawa, Y | 1 |
| Nakanishi, M | 1 |
| Harada, M | 1 |
| Fujiwara, M | 1 |
| Murakami, M | 1 |
| Ueshima, K | 1 |
| Nakao, K | 1 |
| Scholze, J | 1 |
| Steger, F | 1 |
| Hautmann, MG | 1 |
| Kölbl, O | 1 |
| Staessen, JA | 1 |
| Thijisq, L | 1 |
| Fagard, R | 1 |
| Celis, H | 1 |
| Birkenhäger, WH | 1 |
| Bulpitt, CJ | 1 |
| de Leeuw, PW | 1 |
| Fletcher, AE | 1 |
| Forette, F | 1 |
| Leonetti, G | 1 |
| McCormack, P | 1 |
| Nachev, C | 1 |
| O'Brien, E | 1 |
| Rodicio, JL | 1 |
| Rosenfeld, J | 1 |
| Sarti, C | 1 |
| Tuomilehto, J | 1 |
| Webster, J | 1 |
| Yodfat, Y | 1 |
| Zanchetti, A | 1 |
| Kaur, AH | 1 |
| Singh, J | 1 |
| Srivastava, RK | 1 |
| Mathur, SK | 1 |
| Pérez-Cao, A | 1 |
| Gil-Loyzaga, P | 1 |
| Merchàn-Pérez, A | 1 |
| Tamargo, J | 1 |
| Wang, M | 1 |
| Liu, WW | 1 |
| Wan, XP | 1 |
| Li, ZW | 1 |
| Fink, KS | 1 |
| Ellsworth, A | 1 |
| Dixon, IM | 1 |
| Lee, SL | 1 |
| Dhalla, NS | 1 |
| Hamilton, DV | 1 |
| Barnes, PC | 1 |
| Bowles, RM | 1 |
| Rajaratnam, DV | 1 |
| Comerford, MB | 1 |
| Ginks, WR | 1 |
| Ginks, SE | 1 |
| Goves, JR | 1 |
| Grabau, WJ | 1 |
| Malcolm, JP | 1 |
| Pham, NA | 1 |
| Suessmilch, R | 1 |
| Hasse, H | 1 |
| Becker, CH | 1 |
| Schmidt, J | 1 |
| Pham, TL | 1 |
| Ren, XL | 3 |
| Lin, CX | 3 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Stroke Prediction Study Using a Model Based on Internet Search Queries[NCT04755959] | 450 participants (Anticipated) | Observational | 2021-02-28 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitrendipine and Myocardial Infarction
| Article | Year |
|---|---|
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydrop | 2004 |
Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Fel | 1987 |
12 other studies available for nitrendipine and Myocardial Infarction
| Article | Year |
|---|---|
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Body Weight; Calcium Channe | 2009 |
[Isolated systolic hypertension].
Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Enalapril; Female; Human | 2009 |
5-FU-induced cardiac toxicity--an underestimated problem in radiooncology?
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma; Cardiotoxins; Chemoradiotherapy; Electrocardiograp | 2012 |
Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats.
Topics: Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Female; Heart; Isoproterenol; L-Lact | 1995 |
Effects of oxodipine and nitrendipine on the size of experimental myocardial infarct in the rat.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Isoprotere | 1994 |
[Protective effects of nitrendipine against myocardial infarction in rabbits].
Topics: Animals; Creatine Kinase; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; My | 1993 |
Antihypertensive treatment and CHD in the elderly.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; | 1999 |
Nitrendipine binding in congestive heart failure due to myocardial infarction.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Heart Fail | 1990 |
Characterization of the binding parameters of 3H-nitrendipine as a Ca2+-channel blocker in the myocardial membrane of the infarction region of mini-pigs.
Topics: Adenosine Triphosphatases; Affinity Labels; Animals; Calcium Channel Blockers; Calcium Channels; Mem | 1989 |
[The electrophysiologic effect of atenolol and nitrendipine on normal and ischemic rabbit myocardium in situ. II. Effects on effective refractory periods and its dispersion].
Topics: Action Potentials; Animals; Atenolol; Female; Heart; Male; Myocardial Infarction; Nitrendipine; Rabb | 1989 |
[The electrophysiologic effect of atenolol and nitrendipine on normal and ischemic rabbit myocardium in situ. I. Effects on transmembrane potential].
Topics: Action Potentials; Animals; Atenolol; Female; Heart; Male; Myocardial Infarction; Nitrendipine; Rabb | 1989 |
[The electrophysiologic effect of atenolol and nitrendipine on normal and ischemic rabbit myocardium in situ. III. Effects on ventricular fibrillation threshold].
Topics: Animals; Atenolol; Electric Stimulation; Electrophysiology; Female; Male; Myocardial Infarction; Nit | 1989 |